A small molecule species specifically inhibits Fusarium myosin I

Environmental Microbiology

Volumn 17, Issue 8, 2015, Pages 2735-2746

  Zhang, Chengqi ^a   Chen, Yun ^a   Yin, Yanni ^a   Ji, Huan Hong ^b   Shim, Won Bo ^c   Hou, Yiping ^d   Zhou, Mingguo ^d   Li, Xiang dong ^b   Ma, Zhonghua ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b INSTITUTE OF ZOOLOGY   (China)

^c TEXAS A AND M UNIVERSITY   (United States)

^d NANJING AGRICULTURAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

FUNGI; FUSARIUM; GIBBERELLA ZEAE; MAGNAPORTHE GRISEA;

2-CYANO-3-AMINO-3-PHENYLACRYLIC ACID; ADENOSINE TRIPHOSPHATASE; AMINO ACID; ANTIFUNGAL AGENT; FUNGICIDE; MYOSIN I; PHENYLPROPIONIC ACID DERIVATIVE;

ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; FOOD GRAIN; FUSARIUM; GENE EXPRESSION PROFILING; GENETICS; MAGNAPORTHE; MICROBIOLOGY; PATHOGENICITY; PLANT DISEASE;

ADENOSINE TRIPHOSPHATASES; AMINO ACIDS; ANTIFUNGAL AGENTS; EDIBLE GRAIN; FUNGICIDES, INDUSTRIAL; FUSARIUM; GENE EXPRESSION PROFILING; MAGNAPORTHE; MYOSIN TYPE I; PHENYLPROPIONATES; PLANT DISEASES;

EID: 84939261209     PISSN: 14622912     EISSN: 14622920     Source Type: Journal    
DOI: 10.1111/1462-2920.12711     Document Type: Article

References (48)

1. Azad, M.A., and Wright, G.D. (2012) Determining the mode of action of bioactive compounds. Bioorg Med Chem 20: 1929-1939.
2. Becher, R., Hettwer, U., Karlovsky, P., Deising, H.B., and Wirsel, S.G. (2010) Adaptation of Fusarium graminearum to tebuconazole yielded descendants diverging for levels of fitness, fungicide resistance, virulence, and mycotoxin production. Phytopathology 100: 444-453.
3. Becher, R., Weihmann, F., Deising, H.B., and Wirsel, S.G. (2011) Development of a novel multiplex DNA microarray for Fusarium graminearum and analysis of azole fungicide responses. BMC Genomics 12: 52.
4. Bond, L.M., Tumbarello, D.A., Kendrick-Jones, J., and Buss, F. (2013) Small-molecule inhibitors of myosin proteins. Future Med Chem 5: 41-52.
5. Bruno, K.S., Tenjo, F., Li, L., Hamer, J.E., and Xu, J.R. (2004) Cellular localization and role of kinase activity of PMK1 in Magnaporthe grisea. Eukaryot Cell 3: 1525-1532.
6. Chen, Y., and Zhou, M.G. (2009) Characterization of Fusarium graminearum isolates resistant to both carbendazim and a new fungicide JS399-19. Phytopathology 99: 441-446.
7. Chen, Y., Chen, C., Zhou, M., Wang, J., and Zhang, W. (2009) Monogenic resistance to a new fungicide, JS399-19, in Gibberella zeae. Plant Pathol 58: 565-570.
8. Chinthalapudi, K., Taft, M.H., Martin, R., Heissler, S.M., Preller, M., Hartmann, F.K., etal. (2011) Mechanism and specificity of pentachloropseudilin-mediated inhibition of myosin motor activity. J Biol Chem 286: 29700-29708.
9. Crawley, S.W., Marc, A., Lee, S.-F., Li, Z., Chitayat, S., Smith, S.P., and Côté, G.P. (2006) Identification and characterization of an 8kDa light chain associated with Dictyostelium discoideum MyoB, a class I myosin. J Biol Chem 281: 6307-6315.
10. Dean, R., Van Kan, J.A., Pretorius, Z.A., Hammond-Kosack, K.E., Di Pietro, A., Spanu, P.D., etal. (2012) The Top 10 fungal pathogens in molecular plant pathology. Mol Plant Pathol 13: 414-430.
11. Durrbach, A., Collins, K., Matsudaira, P., Louvard, D., and Coudrier, E. (1996) Brush border myosin I truncated in the motor domain impairs the distribution and the function of endocytic compartments in an hepatoma cell line. Proc Natl Acad Sci USA 93: 7053-7058.
12. Geli, M.I., and Riezman, H. (1996) Role of type I myosins in receptor-mediated endocytosis in yeast. Science 272: 533-535.
13. Goodson, H.V., Anderson, B.L., Warrick, H.M., Pon, L.A., and Spudich, J.A. (1996) Synthetic lethality screen identifies a novel yeast myosin I gene (MYO5): myosin I proteins are required for polarization of the actin cytoskeleton. J Cell Biol 133: 1277-1291.
14. Jiang, J.H., Liu, X., Yin, Y.N., and Ma, Z.H. (2011) Involvement of a velvet protein FgVeA in the regulation of asexual development, lipid and secondary metabolisms and virulence in Fusarium graminearum. PLoS ONE 6: e28291.
15. Jongeneel, C.V., Iseli, C., Stevenson, B.J., Riggins, G.J., Lal, A., Mackay, A., etal. (2003) Comprehensive sampling of gene expression in human cell lines with massively parallel signature sequencing. Proc Natl Acad Sci USA 100: 4702-4705.
16. Kornt, E., and Pollard, T. (1993) Inhibition of contractile vacuole function in vivo by antibodies against myosin I. Nature 365: 841-843.
17. Laakso, J.M., Lewis, J.H., Shuman, H., and Ostap, E.M. (2008) Myosin I can act as a molecular force sensor. Science 321: 133-136.
18. Lee, W.L., Bezanilla, M., and Pollard, T.D. (2000) Fission yeast myosin I, Myo1p, stimulates actin assembly by Arp2/3 complex and shares functions with WASp. J Cell Biol 151: 789-800.
19. Li, H., Diao, Y., Wang, J., Chen, C., Ni, J., and Zhou, M. (2008) JS399-19, a new fungicide against wheat scab. Crop Prot 27: 90-95.
20. 2+-induced activation of ATPase activity of myosin Va is accompanied with a large conformational change. Biochem Biophys Res Commun 315: 538-545.
21. Liu, X., Osherov, N., Yamashita, R., Brzeska, H., Korn, E.D., and May, G.S. (2001) Myosin I mutants with only 1% of wild-type actin-activated MgATPase activity retain essential in vivo function(s). Proc Natl Acad Sci USA 98: 9122-9127.
22. Liu, X., Yin, Y.N., Wu, J.B., Jiang, J.H., and Ma, Z.H. (2010) Identification and characterization of carbendazim-resistant isolates of Gibberella zeae. Plant Dis 94: 1137-1142.
23. Liu, X., Yu, F., Schnabel, G., Wu, J., Wang, Z., and Ma, Z. (2011) Paralogous cyp51 genes in Fusarium graminearum mediate differential sensitivity to sterol demethylation inhibitors. Fungal Genet Biol 48: 113-123.
24. Lu, Z.K., Shen, M., Cao, Y., Zhang, H.M., Yao, L.L., and Li, X.D. (2012) Calmodulin bound to the first IQ motif is responsible for calcium-dependent regulation of myosin 5a. J Biol Chem 287: 16530-16540.
25. Ma, Z., and Michailides, T.J. (2005) Advances in understanding molecular mechanisms of fungicide resistance and molecular detection of resistant genotypes in phytopathogenic fungi. Crop Prot 24: 853-863.
26. McGoldrick, C.A., Gruver, C., and May, G.S. (1995) myoA of Aspergillus nidulans encodes an essential myosin I required for secretion and polarized growth. J Cell Biol 128: 577-587.
27. McMullen, M., Bergstrom, G., De Wolf, E., Dill-Macky, R., Hershman, D., Shaner, G., and Van Sanford, D. (2012) A unified effort to fight an enemy of wheat and barley: Fusarium head blight. Plant Dis 96: 1712-1728.
28. Mermall, V., Post, P.L., and Mooseker, M.S. (1998) Unconventional myosins in cell movement, membrane traffic, and signal transduction. Science 279: 527-533.
29. Müllenborn, C., Steiner, U., Ludwig, M., and Oerke, E.C. (2008) Effect of fungicides on the complex of Fusarium species and saprophytic fungi colonizing wheat kernels. Eur J Plant Pathol 120: 157-166.
30. Neuhaus, E.M., and Soldati, T. (2000) A myosin I is involved in membrane recycling from early endosomes. J Cell Biol 150: 1013-1026.
31. Oberholzer, U., Marcil, A., Leberer, E., Thomas, D.Y., and Whiteway, M. (2002) Myosin I is required for hypha formation in Candida albicans. Eukaryot Cell 1: 213-228.
32. Osherov, N., and May, G.S. (2000) In vivo function of class I myosins. Cell Motil Cytoskeleton 47: 163-173.
33. Palchaudhuri, R., and Hergenrother, P.J. (2011) Transcript profiling and RNA interference as tools to identify small molecule mechanisms and therapeutic potential. ACS Chem Biol 6: 21-33.
34. Pestka, J.J., and Smolinski, A.T. (2005) Deoxynivalenol: toxicology and potential effects on humans. J Toxicol Environ Health B Crit Rev 8: 39-69.
35. Proctor, R.H., Hohn, T.M., and McCormick, S.P. (1995) Reduced virulence of Gibberella zeae caused by disruption of a trichothecene toxin biosynthetic gene. Mol Plant Microbe Interact 8: 593-601.
36. Ramirez, M.L., Chulze, S., and Magan, N. (2004) Impact of environmental factors and fungicides on growth and deoxynivalenol production by Fusarium graminearum isolates from Argentinian wheat. Crop Prot 23: 117-125.
37. Raposo, G., Cordonnier, M.N., Tenza, D., Menichi, B., Dürrbach, A., Louvard, D., and Coudrier, E. (1999) Association of myosin I alpha with endosomes and lysosomes in mammalian cells. Mol Biol Cell 10: 1477-1494.
38. Sato, S.I., Murata, A., Shirakawa, T., and Uesugi, M. (2010) Biochemical target isolation for novices: affinity-based strategies. Chem Biol 17: 616-623.
39. Son, H., Seo, Y.S., Min, K., Park, A.R., Lee, J., Jin, J.M., etal. (2011) A phenome-based functional analysis of transcription factors in the cereal head blight fungus, Fusarium graminearum. PLoS Pathog 7: e1002310.
40. Steiner, B., Kurz, H., Lemmens, M., and Buerstmayr, H. (2009) Differential gene expression of related wheat lines with contrasting levels of head blight resistance after Fusarium graminearum inoculation. Theor Appl Genet 118: 753-764.
41. Temesvari, L.A., Bush, J.M., Peterson, M.D., Novak, K.D., Titus, M.A., and Cardelli, J.A. (1996) Examination of the endosomal and lysosomal pathways in Dictyostelium discoideum myosin I mutants. J Cell Sci 109: 663-673.
42. Wang, C., Zhang, S., Hou, R., Zhao, Z., Zheng, Q., Xu, Q., etal. (2011) Functional analysis of the kinome of the wheat scab fungus Fusarium graminearum. PLoS Pathog 7: e1002460.
43. Wang, L.G., Ni, J.P., Wang, F.Y., Diao, Y.M., and Wei, P. (2004) The research on biological activities of new fungicide JS399-19. Chin J Pestic 43: 380-383.
44. Xu, X., and Nicholson, P. (2009) Community ecology of fungal pathogens causing wheat head blight. Annu Rev Phytopathol 47: 83-103.
45. Yamashita, R.A., and May, G.S. (1998) Constitutive activation of endocytosis by mutation of myoA, the myosin I gene of Aspergillus nidulans. J Biol Chem 273: 14644-14648.
46. Yin, Y., Liu, X., Li, B., and Ma, Z. (2009) Characterization of sterol demethylation inhibitor-resistant isolates of Fusarium asiaticum and F.graminearum collected from wheat in China. Phytopathology 99: 487-497.
47. Yu, J.H., Hamari, Z., Han, K.H., Seo, J.A., Reyes-Dominguez, Y., and Scazzocchio, C. (2004) Double-joint PCR: a PCR-based molecular tool for gene manipulations in filamentous fungi. Fungal Genet Biol 41: 973-981.
48. Zhang, Y.J., Zhang, X., Chen, C.J., Zhou, M.G., and Wang, H.C. (2010) Effects of fungicides JS399-19, azoxystrobin, tebuconazloe, and carbendazim on the physiological and biochemical indices and grain yield of winter wheat. Pestic Biochem Phys 98: 151-157.