In vivo function of class I myosins

Cell Motility and the Cytoskeleton

Volumn 47, Issue 3, 2000, Pages 163-173

  Osherov, Nir ^a   May, Gregory S ^a  

^a UNIVERSITY OF TEXAS   (United States)

Author keywords

Acan125; Apr2 3; Class I myosin; PAK; WASP family proteins

Indexed keywords

ACTIN; CLASS 1 MYOSIN; MYOSIN; UNCLASSIFIED DRUG;

ACANTHAMOEBA CASTELLANII; AMINO ACID SEQUENCE; ASPERGILLUS NIDULANS; BINDING SITE; CYTOSKELETON; DICTYOSTELIUM DISCOIDEUM; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME BINDING; ENZYME STRUCTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; REVIEW; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY; VERTEBRATE;

ANIMALS; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; KINETICS; MODELS, BIOLOGICAL; MYOSINS; PROTEIN STRUCTURE, TERTIARY;

ACANTHAMOEBA CASTELLANII; ASPERGILLUS; DICTYOSTELIUM DISCOIDEUM; EMERICELLA NIDULANS; SACCHAROMYCES CEREVISIAE; VERTEBRATA;

EID: 0033732904     PISSN: 08861544     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-0169(200011)47:3<163::AID-CM1>3.0.CO;2-U     Document Type: Review

References (65)

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2. The Src homology domain 3 (SH3) of a yeast type I myosin, Myo5p, binds to verprolin and is required for targeting to sites of action polarization
3. Differential localization of Acanthamoeba myosin I isoforms
4. Quantification and Localization of phosphorylated myosin I isoforms in Acanthamoeba castellanii
5. Regulations of the enzymatic and motor activities of myosin I
6. The localization and sequence of the phosphorylation sites of Acanthamoeba myosin I. An improved method for locating the phosphorylated amino acid
7. The catalytic domain of Acanthamoeba myosin I heavy chain kinase: Identification and characterization following tryptic cleavage of the native enzyme
8. 2+ ATPase activity
9. Calmodulin dissociation regulates brush border myosin I (110-kD-calmodulin) mechanochemical activity in-vitro
10. Myosin I
11. Transient kinetic analysis of the 130-kDa Myosin I (MYR-1 gene product) from rat liver
12. The 110-kD protein-calmodulin complex of the intestinal microvillus is an actin-activated MgATPase
13. Myosin I contributes to the generation of resting cortical tension
14. p21-activated protein kinase: A crucial component of morphological signaling?
15. Localization and specificity of the phospholipid and actin binding sites on the tail of Acanthamoeba myosin IC
16. Inhibition of contractile vacuole function in vivo by antibodies against myosin I
17. Brush border myosin I truncated in the motor domain impairs the distribution and the function of endocytic compartments in a hepatoma cell line
18. Truncated Brush Border Myosin I affects membrane traffic in polarized epithelial cells
19. A role for myosin I in actin assembly through interactions with Vrp1p, Bee1p and the Arp 2/3 complex
20. Myosin I is located at the leading edges of locomoting Dictyostelium amoebae
21. Role of type I myosins in receptor mediated endocytosis in yeast
22. Synthetic lethality screen identifies a novel yeast myosin I gene (myo5): Myosin I proteins are required for polarization of the actin cytoskeleton
23. Rho GTPases and the actin cytoskeleton
24. Unconventional myosins in inner-ear sensory epithelia
25. Brush border myosin-I structure and ADP-dependent conformational changes revealed by cryoelectron microscopy and image analysis
26. Kinetic characterization of brush border myosin-I ATPase
27. Three-dimensional structure of Acanthamoeba castellanii myosin IB determined by cryoelectron microscopy of decorated actin filaments
28. Generation and characterization of Dictyostelium cell deficient in a myosin I heavy chain isoform
29. Sequence, expression pattern, intracellular localization and targeted disruption of the Dictyostelium myosin ID heavy chain isoform
30. Dictyostelium mutants lacking multiple classic myosin I isoforms reveal combinations of shared and distinct functions
31. Myosin I, Arp 2/3, CapZ and a 116 kDa leucine rich repeat (LLR) protein are present in a complex critical for the formation of actin rich extensions
32. Direct involvement of yeast type I myosins in Cdc42-dependent actin polymerization
33. Isolation and characterization of three Dictyostelium myosin I isozymes
34. Cloning and characterization of a Dictyostelium myosin I heavy chain kinase activated by CdC42 and Rac
35. Organization and ligand binding properties of the tail of Acanthamoeba myosin-IA. Identification of an actin-binding site in the basic (tail homology-1) domain
36. Purification and characterization of a third isoform of myosin I from A. castellanii
37. 2+-ATPase activity of Acanthamoeba myosin I
38. Identification and organization of the components in the isolated microvillus cytoskeleton
39. MyoA of Aspergillus nidulans encodes an essential myosin I required for secretion and polarized growth
40. Localization of Dictyostelium myoB and myoD to filopodia and cell-cell contact sites using isoform specific antibodies
41. Myosin I overexpression impairs cell migration
42. The myosin I SH3 domain and TEDS rule phosphorylation site are required for in vivo function
43. Dictyostelium myosin I double mutants exhibit conditional defects in pinocytosis
44. Structural requirements for in vivo myosin I function in Aspergillus nidulans
45. Biochemical kinetic characterization of the Acanthamoeba myosin I ATPase
46. Overlapping functions of myosin I isoforms?
47. Acanthamoeba myosin I. Isolation from Acanthamoeba castellanii of an enzyme similar to muscle myosin
48. Localization of the rat myosin I molecules myr1 and myr2 and in vivo targeting of their tail domains
49. Dictyostelium myosin IK is involved in the maintenance of cortical tension and affects motility and phagocytosis
50. 2+ binding to its light chain calmodulin
51. Targeting of the myosin-I myr3 to intercellular adherens type junctions induced by dominant active Cdc42 in HeLa Cells
52. Progress in protrusion: The tell-tale scar
53. The unconventional myosin encoded by the myoA gene plays a role in Dictyostelium motility
54. Molecular genetic analysis of myoF, a new Dictyostelium myosin I gene
55. The motor protein of myosin-I produces its working stroke in two steps
56. Function of myosin-V in filopodial extension of neuronal growth cones
57. Analysis of the regulatory phosphorylation site in Acanthamoeba myosin IC by using site-directed mutagenesis
58. Myosin IB null mutants of Dictyostelium exhibit abnormalities in motility
59. The phosphorylation site for Ste20p like protein kinases is essential for the function of myosin I in yeast
60. Functions of unconventional myosins
61. Identification of Acan 125 as a myosin-I-binding protein present with myosin-I on cellular organelles of Acanthamoeba
62. The myosin I binding protein Acan 125 binds the SH3 domain and belongs to the superfamily of leucine-rich repeat proteins
63. Constitutive activation of endocytosis by mutation of myoA, the myosin I gene of Aspergillus nidulans
64. Localization of wild type and mutant class I myosin proteins in Aspergillus nidulans using GFP-fusion proteins
65. Myosin I moves actin filaments on a phospholipid substrate: Implications for membrane targeting