The Contribution of Missense Mutations in Core and Rim Residues of Protein-Protein Interfaces to Human Disease

Journal of Molecular Biology

Volumn 427, Issue 17, 2015, Pages 2886-2898

  David, Alessia ^a   Sternberg, Michael J E ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

core and rim interface; human disease; nsSNPs; protein protein interaction; SAVs

Indexed keywords

AMINO ACID; HRAS PROTEIN, HUMAN; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE PHOSPHODIESTERASE; PHOSPHOLIPASE C EPSILON; PROTEIN BINDING; PROTEIN P21;

AMINO ACID SUBSTITUTION; ARTICLE; COMPLEX FORMATION; GENETIC CONSERVATION; GENETIC POLYMORPHISM; MISSENSE MUTATION; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; BINDING SITE; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; PROTEIN ANALYSIS; PROTEIN CONFORMATION; SINGLE NUCLEOTIDE POLYMORPHISM;

AMINO ACID SUBSTITUTION; BINDING SITES; HUMANS; MOLECULAR SEQUENCE DATA; MUTATION, MISSENSE; PHOSPHOINOSITIDE PHOSPHOLIPASE C; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN INTERACTION MAPPING; PROTO-ONCOGENE PROTEINS P21(RAS);

EID: 84939260732     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2015.07.004     Document Type: Article

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