Splicing changes in SMA mouse motoneurons and SMN-depleted neuroblastoma cells: Evidence for involvement of splicing regulatory proteins

RNA Biology

Volumn 11, Issue 11, 2014, Pages 1430-1446

  Huo, Qing ^a   Kayikci, Melis ^b   Odermatt, Philipp ^a   Meyer, Kathrin ^a,d   Michels, Olivia ^a   Saxena, Smita ^a,c   Ule, Jernej ^b,e   Schümperli, Daniel ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^c FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

^d NATIONWIDE CHILDREN S HOSPITAL   (United States)

^e UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Exon junction microarray; Laser capture microdissection; Major spliceosome; Minor spliceosome; Motoneurons; Neurodegerative disease; SnRNP assembly; Spinal muscular atrophy; Splicing; Splicing regulators

Indexed keywords

REGULATOR PROTEIN; SMALL NUCLEAR RIBONUCLEOPROTEIN; SMALL NUCLEAR RNA; SURVIVAL MOTOR NEURON PROTEIN; SURVIVAL MOTOR NEURON PROTEIN 1; SURVIVAL MOTOR NEURON PROTEIN 2; T LYMPHOCYTE RECEPTOR BETA CHAIN; MEMBRANE PROTEIN; RBFOX1 PROTEIN, MOUSE; RNA BINDING PROTEIN; SEPTIN; SEPTIN 9, MOUSE; TMEM41B PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; EXON; INTRON RETENTION; LASER CAPTURE MICRODISSECTION; MICROARRAY ANALYSIS; MOTONEURON; MOUSE; NEUROBLASTOMA CELL; NONHUMAN; RNA SPLICING; SPINAL MUSCULAR ATROPHY; SPLICEOSOME; SPLICING DEFECT; ANIMAL; CELL CULTURE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; INTRON; KNOCKOUT MOUSE; METABOLISM; NEUROBLASTOMA; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TRANSGENIC MOUSE; TUMOR CELL LINE; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CELL LINE, TUMOR; CELLS, CULTURED; GENE EXPRESSION REGULATION; HUMANS; INTRONS; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MOTOR NEURONS; MUSCULAR ATROPHY, SPINAL; NEUROBLASTOMA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA SPLICING; RNA-BINDING PROTEINS; SEPTINS; SMN COMPLEX PROTEINS;

EID: 84939253358     PISSN: 15476286     EISSN: 15558584     Source Type: Journal    
DOI: 10.1080/15476286.2014.996494     Document Type: Article

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