The 68kDa subunit of mammalian cleavage factor I interacts with the U7 small nuclear ribonucleoprotein and participates in 3′-end processing of animal histone mRNAs

Nucleic Acids Research

Volumn 38, Issue 21, 2010, Pages 7637-7650

  Ruepp, Marc David ^a   Vivarelli, Silvia ^b   Pillai, Ramesh S ^a   Kleinschmidt, Nicole ^a   Azzouz, Teldja N ^a   Barabino, Silvia M L ^b   Schümperli, Daniel ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b UNIVERSITY OF MILANO BICOCCA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CLEAVAGE STIMULATION FACTOR; HISTONE; MAMMALIAN CLEAVAGE FACTOR 1; MESSENGER RNA; SMALL NUCLEAR RIBONUCLEOPROTEIN; SMALL NUCLEAR RIBONUCLEOPROTEIN LSM11; SMALL NUCLEAR RIBONUCLEOPROTEIN U7; UNCLASSIFIED DRUG; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR; LSM11 PROTEIN, MOUSE; RNA PRECURSOR;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; CONTROLLED STUDY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IN VITRO STUDY; NUCLEOTIDE SEQUENCE; POLYADENYLATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEPLETION; PROTEIN DETERMINATION; PROTEIN PROTEIN INTERACTION; RNA CLEAVAGE; RNA PROCESSING; ANIMAL; BINDING SITE; CELL LINE; CHEMISTRY; GENETICS; METABOLISM; MOUSE; MUTATION; PROTEIN SUBUNIT;

ANIMALIA; MAMMALIA; METAZOA;

ANIMALS; BINDING SITES; CELL LINE; HISTONES; HUMANS; MICE; MRNA CLEAVAGE AND POLYADENYLATION FACTORS; MUTATION; PROTEIN SUBUNITS; RIBONUCLEOPROTEIN, U7 SMALL NUCLEAR; RIBONUCLEOPROTEINS, SMALL NUCLEAR; RNA 3' END PROCESSING; RNA PRECURSORS; RNA, MESSENGER;

EID: 78649859222     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkq613     Document Type: Article

References (42)

1. Mandel, C. R., Bai, Y. and Tong, L. (2008) Protein factors in pre-mRNA 3′-end processing. Cell Mol. Life Sci., 65, 1099-1122.
2. Keller, W., Bienroth, S., Lang, K. M. and Christofori, G. (1991) Cleavage and polyadenylation factor CPF specifically interacts with the pre-mRNA 3′ processing signal AAUAAA. EMBO J., 10, 4241-4249.
3. MacDonald, C. C., Wilusz, J. and Shenk, T. (1994) The 64-kilodalton subunit of the CstF polyadenylation factor binds to pre-mRNAs downstream of the cleavage site and influences cleavage site location. Mol. Cell. Biol., 14, 6647-6654.
4. Dominski, Z. and Marzluff, W. F. (2007) Formation of the 3′ end of histone mRNA: getting closer to the end. Gene, 396, 373-390.
5. Pillai, R. S., Will, C. L., Luhrmann, R., Schumperli, D. and Muller, B. (2001) Purified U7 snRNPs lack the Sm proteins D1 and D2 but contain Lsm10, a new 14kDa Sm D1-like protein. EMBO J., 20, 5470-5479.
6. Pillai, R. S., Grimmler, M., Meister, G., Will, C. L., Luhrmann, R., Fischer, U. and Schumperli, D. (2003) Unique Sm core structure of U7 snRNPs: assembly by a specialized SMN complex and the role of a new component, Lsm11, in histone RNA processing. Genes Dev., 17, 2321-2333.
7. Wang, Z. F., Whitfield, M. L., Ingledue, T. C., Dominski, Z. and Marzluff, W. F. (1996) The protein that binds the 3′ end of histone mRNA: a novel RNA-binding protein required for histone pre-mRNA processing. Genes Dev., 10, 3028-3040.
8. Martin, F., Schaller, A., Eglite, S., Schumperli, D. and Muller, B. (1997) The gene for histone RNA hairpin binding protein is located on human chromosome 4 and encodes a novel type of RNA binding protein. EMBO J., 15, 769-778.
9. Dominski, Z., Erkmann, J. A., Yang, X., Sanchez, R. and Marzluff, W. F. (2002) A novel zinc finger protein is associated with U7 snRNP and interacts with the stem-loop binding protein in the histone pre-mRNP to stimulate 3′-end processing. Genes Dev., 16, 58-71.
10. Gick, O., Kramer, A., Vasserot, A. and Birnstiel, M. L. (1987) Heat-labile regulatory factor is required for 3′ processing of histone precursor mRNAs. Proc. Natl Acad. Sci. USA, 84, 8937-8940.
11. Luscher, B. and Schumperli, D. (1987) RNA 3′ processing regulates histone mRNA levels in a mammalian cell cycle mutant. A processing factor becomes limiting in G1-arrested cells. EMBO J., 6, 1721-1726.
12. Chen, F., MacDonald, C. C. and Wilusz, J. (1995) Cleavage site determinants in the mammalian polyadenylation signal. Nucleic Acids Res., 23, 2614-2620.
13. Muller, B. and Schumperli, D. (1997) The U7 snRNP and the hairpin binding protein: key players in histone mRNA metabolism. Semin. Cell Dev. Biol., 8, 567-576.
14. Furger, A., Schaller, A. and Schumperli, D. (1998) Functional importance of conserved nucleotides at the histone RNA 3′ processing site. RNA, 4, 246-256.
15. Dominski, Z., Yang, X. C. and Marzluff, W. F. (2005) The polyadenylation factor CPSF-73 is involved in histone-pre-mRNA processing. Cell, 123, 37-48.
16. Kolev, N. G. and Steitz, J. A. (2005) Symplekin and multiple other polyadenylation factors participate in 3′-end maturation of histone mRNAs. Genes Dev., 19, 2583-2592.
17. Friend, K., Lovejoy, A. F. and Steitz, J. A. (2007) U2 snRNP binds intronless histone pre-mRNAs to facilitate U7-snRNP-dependent 3′ end formation. Mol. Cell, 28, 240-252.
18. Kyburz, A., Friedlein, A., Langen, H. and Keller, W. (2006) Direct interactions between subunits of CPSF and the U2 snRNP contribute to the coupling of pre-mRNA 3′ end processing and splicing. Mol. Cell, 23, 195-205.
19. R̈uegsegger, U., Blank, D. and Keller, W. (1998) Human pre-mRNA cleavage factor Im is related to spliceosomal SR proteins and can be reconstituted in vitro from recombinant subunits. Mol. Cell, 1, 243-253.
20. Rüegsegger, U., Beyer, K. and Keller, W. (1996) Purification and characterization of human cleavage factor I(m) involved in the 3′ end processing of messenger RNA precursors. J. Biol. Chem., 271, 6107-6113.
21. Dettwiler, S., Aringhieri, C., Cardinale, S., Keller, W. and Barabino, S. M. L. (2004) Distinct sequence motifs within the 68-kDa subunit of cleavage factor im mediate RNA binding, protein-protein interactions, and Subcellular Localization. J. Biol. Chem., 279, 35788-35797.
22. Cardinale, S., Cisterna, B., Bonetti, P., Aringhieri, C., Biggiogera, M. and Barabino, S. M. L. (2007) Subnuclear localization and dynamics of the pre-mRNA 3′ end processing factor mammalian cleavage factor I 68-kDa subunit. Mol. Biol. Cell, 18, 1282-1292.
23. Azzouz, T. N., Gruber, A. and Schumperli, D. (2005) U7 snRNP-specific Lsm11 protein: dual binding contacts with the 100 kDa zinc finger processing factor (ZFP100) and a ZFP100-independent function in histone RNA 3′ end processing. Nucleic Acids. Res., 33, 2106-2117.
24. Ruepp, M. D., Aringhieri, C., Vivarelli, S., Cardinale, S., Paro, S., Schumperli, D. and Barabino, S. M. L. (2009) Mammalian pre-mRNA 3′ end processing factor CF Im68 functions in mRNA export. Mol. Biol. Cell, 20, 5211-5223.
25. Shyu, Y. J., Liu, H., Deng, X. and Hu, C. D. (2006) Identification of new fluorescent protein fragments for bimolecular fluorescence complementation analysis under physiological conditions. Biotechniques, 40, 61-66.
26. Brummelkamp, T. R., Bernards, R. and Agami, R. (2002) A system for stable expression of short interfering RNAs in mammalian cells. Science, 296, 550-553.
27. Paillusson, A., Hirschi, N., Vallan, C., Azzalin, C. M. and Muhlemann, O. (2005) A GFP-based reporter system to monitor nonsense-mediated mRNA decay. Nucleic Acids Res., 33, e54.
28. Will, C. L., Kastner, B. and Luhrmann, R. (1994) Analysis of ribonucleoprotein interactions. In Higgins, S. J. and Hames, B. D. (eds), RNA Processing, Vol. 1. Oxford University Press, Oxford, pp. 141-177.
29. Hu, C. D. and Kerppola, T. K. (2003) Simultaneous visualization of multiple protein interactions in living cells using multicolor fluorescence complementation analysis. Nat. Biotech., 21, 539-545.
30. Spycher, C., Streit, A., Stefanovic, B., Albrecht, D., Wittop Koning, T. H. and Schumperli, D. (1994) 3′ end processing of mouse histone pre-mRNA: evidence for additional base-pairing between U7 snRNA and pre-mRNA. Nucleic Acids Res., 22, 4023-4030.
31. Gilbert, C., Kristjuhan, A., Winkler, G. S. and Svejstrup, J. Q. (2004) Elongator interactions with nascent mRNA revealed by RNA immunoprecipitation. Mol. Cell, 14, 457-464.
32. Chittum, H. S., Lane, W. S., Carlson, B. A., Roller, P. P., Lung, F. D., Lee, B. J. and Hatfield, D. L. (1998) Rabbit beta-globin is extended beyond its UGA stop codon by multiple suppressions and translational reading gaps. Biochemistry, 37, 10866-10870.
33. Azzouz, T. N. and Schumperli, D. (2003) Evolutionary conservation of the U7 small nuclear ribonucleoprotein in Drosophila melanogaster. RNA, 9, 1532-1541.
34. Hu, C. D., Chinenov, Y. and Kerppola, T. K. (2002) Visualization of interactions among bZIP and Rel family proteins in living cells using bimolecular fluorescence complementation. Mol. Cell, 9, 789-798.
35. Frey, M. R. and Matera, A. G. (1995) Coiled bodies contain U7 small nuclear RNA and associate with specific DNA sequences in interphase human cells [published erratum appears in Proc. Natl Acad. Sci. USA, 1995, 92:8532].
36. Proc. Natl Acad. Sci. USA, 92, 5915-5919.
37. Wagner, E. J. and Marzluff, W. F. (2006) ZFP100, a component of the active U7 snRNP limiting for histone pre-mRNA processing, is required for entry into S phase. Mol. Cell. Biol., 26, 6702-6712.
38. Farber, L. J., Kort, E. J., Wang, P., Chen, J. and Teh, B. T. (2010) The tumor suppressor parafibromin is required for posttranscriptional processing of histone mRNA. Mol. Carcinog., 49, 215-223.
39. Brown, K. M. and Gilmartin, G. M. (2003) A mechanism for the regulation of pre-mRNA 3′ processing by human cleavage factor Im. Mol. Cell, 12, 1467-1476.
40. Kubo, T., Wada, T., Yamaguchi, Y., Shimizu, A. and Handa, H. (2006) Knock-down of 25 kDa subunit of cleavage factor Im in Hela cells alters alternative polyadenylation within 3′-UTRs. Nucleic Acids Res., 34, 6264-6271.
41. Marzluff, W. F. (2005) Metazoan replication-dependent histone mRNAs: a distinct set of RNA polymerase II transcripts. Curr. Opin. Cell Biol., 17, 274-280.
42. Huang, Y. and Steitz, J. A. (2001) Splicing factors SRp20 and 9G8 promote the nucleocytoplasmic export of mRNA. Mol. Cell, 7, 899-905.