Inhibition of colorectal cancer stem cell survival and invasive potential by hsa-miR-140-5p mediated suppression of Smad2 and autophagy

Oncotarget

Volumn 6, Issue 23, 2015, Pages 19735-19746

  Zhai, Haiyan ^a   Fesler, Andrew ^a   Ba, Yufeng ^b   Wu, Song ^c   Ju, Jingfang ^a  

^a STONY BROOK UNIVERSITY   (United States)

^b Henan Cancer Hospital   (China)

^c Stony Brook University   (United States)

Author keywords

Autophagy; Colon cancer stem cell; hsa miR 140 5p; Metastasis; Smad2

Indexed keywords

MICRORNA; MICRORNA 140 5P; SMAD2 PROTEIN; UNCLASSIFIED DRUG; MIRN140 MICRORNA, HUMAN; SMAD2 PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; CANCER GROWTH; CANCER PROGNOSIS; CANCER STAGING; CANCER STEM CELL; CANCER SURVIVAL; CELL CYCLE ARREST; CELL PROLIFERATION; CELL SURVIVAL; COLORECTAL CANCER CELL LINE; CONTROLLED STUDY; DOWN REGULATION; GENE OVEREXPRESSION; IN VITRO STUDY; IN VIVO STUDY; LIVER METASTASIS; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN TARGETING; TUMOR INVASION; ANIMAL; CELL CYCLE CHECKPOINT; CELL MOTION; COLORECTAL NEOPLASMS; DRUG SCREENING; GENE EXPRESSION REGULATION; GENE THERAPY; GENETIC TRANSFECTION; GENETICS; HCT 116 CELL LINE; HUMAN; LIVER TUMOR; METABOLISM; MORTALITY; NONOBESE DIABETIC MOUSE; PATHOLOGY; PHENOTYPE; PROCEDURES; RNA INTERFERENCE; SCID MOUSE; SECONDARY; SIGNAL TRANSDUCTION; TIME FACTOR;

ANIMALS; AUTOPHAGY; CELL CYCLE CHECKPOINTS; CELL MOVEMENT; CELL PROLIFERATION; CELL SURVIVAL; COLORECTAL NEOPLASMS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC THERAPY; HCT116 CELLS; HUMANS; LIVER NEOPLASMS; MICE, INBRED NOD; MICE, SCID; MICRORNAS; NEOPLASM INVASIVENESS; NEOPLASM STAGING; NEOPLASTIC STEM CELLS; PHENOTYPE; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SMAD2 PROTEIN; TIME FACTORS; TRANSFECTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84939243033     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.3771     Document Type: Article

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