Testosterone replacement attenuates cognitive decline in testosterone-deprived lean rats, but not in obese rats, by mitigating brain oxidative stress

Age

Volumn 37, Issue 5, 2015, Pages

  Pintana, Hiranya ^a   Pongkan, Wanpitak ^a   Pratchayasakul, Wasana ^a   Chattipakorn, Nipon ^a   Chattipakorn, Siriporn C ^a  

^a CHIANG MAI UNIVERSITY   (Thailand)

Author keywords

Brain mitochondrial function; Cognitive function; Hippocampal synaptic plasticity; Obese insulin resistance; Testosterone deprivation; Testosterone replacement

Indexed keywords

CASTOR OIL; REACTIVE OXYGEN METABOLITE; TESTOSTERONE; ANDROGEN;

ANDROGEN DEPRIVATION THERAPY; ANDROGEN THERAPY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN MITOCHONDRION; COGNITION; COGNITIVE DECLINE; COGNITIVE DEFECT; CONTROLLED STUDY; HIPPOCAMPUS; HYPOGONADISM; INSULIN SENSITIVITY; LIPID DIET; MALE; METABOLIC PARAMETERS; MOUSE STRAIN; NERVE CELL PLASTICITY; NONHUMAN; ORCHIECTOMY; OXIDATIVE STRESS; RAT; SHAM PROCEDURE; WISTAR RAT; AGING; ANIMAL; BODY WEIGHT; BRAIN; COGNITION DISORDERS; COMPLICATION; DISEASE MODEL; DRUG EFFECTS; METABOLISM; MITOCHONDRION; OBESITY;

AGING; ANDROGENS; ANIMALS; BRAIN; COGNITION; COGNITION DISORDERS; DISEASE MODELS, ANIMAL; MALE; MITOCHONDRIA; NEURONAL PLASTICITY; OBESITY; OXIDATIVE STRESS; RATS; RATS, WISTAR; TESTOSTERONE; THINNESS;

EID: 84939201764     PISSN: 01619152     EISSN: 15744647     Source Type: Journal    
DOI: 10.1007/s11357-015-9827-4     Document Type: Article

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