Low Dopamine D2 Receptor Increases Vulnerability to Obesity Via Reduced Physical Activity, Not Increased Appetitive Motivation

Biological Psychiatry

Volumn 79, Issue 11, 2016, Pages 887-897

  Beeler, Jeff A ^a,b   Faust, Rudolf P ^c   Turkson, Susie ^b   Ye, Honggang ^d   Zhuang, Xiaoxi ^b  

^a CITY UNIVERSITY OF NEW YORK   (United States)

^b XZ) ^*  (United States)

^c Interdisciplinary Scientist Training Program   (United States)

^d UNIVERSITY OF CHICAGO   (United States)

Author keywords

Behavioral thrift; D2R; Dietary induced obesity; Reward deficiency; Running wheels; Voluntary exercise

Indexed keywords

DOPAMINE 2 RECEPTOR; DRD2 PROTEIN, MOUSE; GLUCOSE BLOOD LEVEL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIET INDUCED OBESITY; ENERGY EXPENDITURE; EXERCISE; EXPLORATORY BEHAVIOR; FEMALE; GENE LOCUS; GENE TARGETING; HETEROZYGOTE; HOMOZYGOTE; INCREASED APPETITE; INDIRECT CALORIMETRY; LIPID DIET; MALE; MOTIVATION; MOUSE; NONHUMAN; OBESITY; PHYSICAL ACTIVITY; PRIORITY JOURNAL; RUNNING; TREADMILL EXERCISE; WEIGHT GAIN; 129 MOUSE; ANIMAL; ANIMAL HOUSING; BODY WEIGHT; C57BL MOUSE; DECISION MAKING; DISEASE MODEL; ENERGY METABOLISM; FEEDING BEHAVIOR; GENETIC PREDISPOSITION; GENETICS; GLUCOSE BLOOD LEVEL; INSTRUMENTAL CONDITIONING; METABOLISM; MOTOR ACTIVITY; PHYSIOLOGY; PSYCHOLOGY; TRANSGENIC MOUSE;

ANIMALS; BLOOD GLUCOSE; BODY WEIGHT; CALORIMETRY, INDIRECT; CHOICE BEHAVIOR; CONDITIONING, OPERANT; DISEASE MODELS, ANIMAL; ENERGY METABOLISM; FEEDING BEHAVIOR; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HOUSING, ANIMAL; MALE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, TRANSGENIC; MOTIVATION; MOTOR ACTIVITY; OBESITY; RECEPTORS, DOPAMINE D2;

EID: 84939179520     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2015.07.009     Document Type: Article

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