Impairing the radioresistance of cancer cells by hydrogenated nanodiamonds

Biomaterials

Volumn 61, Issue , 2015, Pages 290-298

  Grall, Romain ^a   Girard, Hugues ^b   Saad, Lina ^a   Petit, Tristan ^b   Gesset, Céline ^b   Combis Schlumberger, Mathilde ^b   Paget, Vincent ^a   Delic, Jozo ^a   Arnault, Jean Charles ^b   Chevillard, Sylvie ^a  

^a INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE   (France)

^b DIF   (France)

Author keywords

Hydrogenated nanodiamonds (H NDs); Oxidative stress; Radiation sensitization; Senescence; H2AX

Indexed keywords

CELL CULTURE; CELL DEATH; DISEASES; ELECTRON AFFINITY; ELECTRON EMISSION; HYDROGENATION; IRRADIATION; OXIDATIVE STRESS; OXYGEN; RADIATION EFFECTS; RADIOTHERAPY;

CANCER CELL LINES; HIGH REACTIVITY; HYDROGENATED NANODIAMONDS; NEGATIVE ELECTRON AFFINITY; OXYGEN SPECIES; POSITIVE CHARGES; RADIORESISTANCE; SENESCENCE;

NANODIAMONDS;

BETA GALACTOSIDASE; GAMMA H2AX; HISTONE H2AX; NANODIAMOND; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; ZINOSTATIN; HYDROGEN; RADIOSENSITIZING AGENT;

ARTICLE; BREAST CANCER CELL LINE; CANCER CELL; CANCER CELL LINE; CELL ADHESION; CELL CYCLE CHECKPOINT; CELL CYCLE REGULATION; CELL DEATH; CELL FUNCTION; CELL GROWTH; CELL MEMBRANE POTENTIAL; CELL PROLIFERATION; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; DNA DAMAGE; DNA END JOINING REPAIR; DNA STRAND BREAKAGE; DRUG CYTOTOXICITY; ENZYME ACTIVITY; EXTRACELLULAR MATRIX; FLOW CYTOMETRY; GAMMA IRRADIATION; HUMAN; HUMAN CELL; HYDROGENATION; OXIDATIVE STRESS; PRIORITY JOURNAL; RADIATION EXPOSURE; RADIOSENSITIVITY; RENAL CANCER CELL LINE; SENESCENCE; ZETA POTENTIAL; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; MATERIALS TESTING; NEOPLASMS, EXPERIMENTAL; PATHOLOGY; RADIATION RESPONSE; RADIATION TOLERANCE; SYNTHESIS; TREATMENT OUTCOME; TUMOR CELL LINE; ULTRASTRUCTURE;

CELL LINE, TUMOR; CELL SURVIVAL; HUMANS; HYDROGEN; MATERIALS TESTING; NANODIAMONDS; NEOPLASMS, EXPERIMENTAL; RADIATION TOLERANCE; RADIATION-SENSITIZING AGENTS; TREATMENT OUTCOME;

EID: 84939172203     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2015.05.034     Document Type: Article

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