Carboxylated nanodiamonds are neither cytotoxic nor genotoxic on liver, kidney, intestine and lung human cell lines

Nanotoxicology

Volumn 8, Issue SUPPL. 1, 2014, Pages 46-56

  Paget, V ^a   Sergent, J A ^a   Grall, R ^a   Altmeyer Morel, S ^a   Girard, H A ^b   Petit, T ^b   Gesset, C ^b   Mermoux, M ^c   Bergonzo, P ^b   Arnault, J C ^b   Chevillard, S ^a,d  

^a INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE   (France)

^b DIF   (France)

^c LEPMI   (France)

^d CEA GRENOBLE   (France)

Author keywords

Confocal and Raman microscopy; Cytotoxicity; Flow cytometry; Genotoxicity; Impedancemetry; Nanodiamonds

Indexed keywords

CARBON; GAMMA HISTONE H2AX; HISTONE H2AX; NANODIAMOND; NANOMATERIAL; POLYSTYRENE; UNCLASSIFIED DRUG; CARBOXYLIC ACID;

ARTICLE; CELL DEATH; CELL LINE; CELL SURVIVAL; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; FLOW CYTOMETRY; GENOTOXICITY; HEALTH HAZARD; HEK293 CELL LINE; HEPG2 CELL LINE; HT 29 CELL LINE; HUMAN; HUMAN CELL; LIVER; LUNG; PHOTOLUMINESCENCE; PRIORITY JOURNAL; RAMAN SPECTROMETRY; CHEMISTRY; DRUG EFFECTS; INTESTINE; KIDNEY;

CARBOXYLIC ACIDS; CELL LINE; FLOW CYTOMETRY; HUMANS; INTESTINES; KIDNEY; LIVER; LUNG; MICROSCOPY, CONFOCAL; NANODIAMONDS;

EID: 84905991509     PISSN: 17435390     EISSN: 17435404     Source Type: Journal    
DOI: 10.3109/17435390.2013.855828     Document Type: Article

References (49)

1. Abramoff MD, Magalhaes PJ, Ram SJ. 2004. Image processing with ImageJ. Biophoton Int 11: 36-42.
2. Alhaddad A, Adam MP, Botsoa J, Dantelle G, Perruchas S, Gacoin T, et al. 2011. Nanodiamond as a vector for siRNA delivery to Ewing sarcoma cells. Small 7: 3087-95.
3. Arnault JC, Petit T, Girard H, Chavanne A, Gesset C, Sennour M, Chaigneau M. 2011. Surface chemical modifications and surface reactivity of nanodiamonds hydrogenated by CVD plasma. Phys Chem Chem Phys 13: 11481-7.
4. Bassan P, Kohler A, Martens H, Lee J, Byrne HJ, Dumas P, et al. 2010. Resonant Mie scattering (RMieS) correction of infrared spectra from highly scattering biological samples. Analyst 135: 268-77.
5. Carpenter AE, Jones TR, Lamprecht MR, Clarke C, Kang IH, Friman O, et al. 2006. CellProfiler: image analysis software for identifying and quantifying cell phenotypes. Genome Biol 7: R100: 1-11.
6. Chang YR, Lee HY, Chen K, Chang CC, Tsai DS, Fu CC, et al. 2008. Mass production and dynamic imaging of fluorescent nanodiamonds. Nat Nanotechnol 3: 284-8.
7. Cheng CY, Perevedentseva E, Tu JS, Chung PH, Cheng CL, Liu KK, et al. 2007. Direct and in vitro observation of growth hormone receptor molecules in A549 human lung epithelial cells by nanodiamond labeling. Appl Phys Lett 90: 163903: 1-3.
8. Girard HA, Arnault JC, Perruchas S, Saada S, Gacoin T, Boilot JP, Bergonzo P. 2010. Hydrogenation of nanodiamonds using MPCVD: a new route toward organic functionalization. Diamond Relat Mater 19: 1117-23.
9. Girard HA, Petit T, Perruchas S, Gacoin T, Gesset C, Arnault JC, Bergonzo P. 2011. Surface properties of hydrogenated nanodiamonds: a chemical investigation. Phys Chem Chem Phys 13: 11517-23.
10. Holder AL, Goth-Goldstein R, Lucas D, Koshland CP. 2010. Particleinduced artifacts in the MTT and LDH viability assays. Chem Res Toxicol 25: 1885-92.
11. Huang H, Pierstorff E, Osawa E, Ho D. 2007. Active nanodiamond hydrogels for chemotherapeutic delivery. Nano Lett 7: 3305-14.
12. Huang LC, Chang HC. 2004. Adsorption and immobilization of cytochrome c on nanodiamonds. Langmuir 20: 5879-84.
13. Jakob B, Durante M. 2012. Radiation dose detection by imaging response in biological targets. Radiat Res 177: 524-32.
14. Jelezko F, Wrachtrup J. 2006. Single defect centres in diamond: a review. Phys. Status Solidi 203: 3207-25.
15. Ke N,Wang X, Xu X, Abassi YA. 2011. The xCELLigence system for real-time and label-free monitoring of cell viability. Methods Mol Biol 740: 33-43.
16. Kroll A, Pillukat MH, Hahn D, Schnekenburger J. 2012. Interference of engineered nanoparticles with in vitro toxicity assays. Arch Toxicol 86: 1123-36.
17. Krueger A. 2011. Beyond the shine: recent progress in applications of nanodiamond. J Mater Chem 21: 12571-8.
18. Krueger A, Stegk J, Liang Y, Lu L, Jarre G. 2008. Biotinylated nanodiamond: simple and efficient functionalization of detonation diamond. Langmuir 24: 4200-4.
19. Kruger A. 2006. Hard and soft: biofunctionalized diamond. Angew Chem Int Ed Engl 45: 6426-7.
20. Lin YC, Perevedentseva E, Tsai LW, Wu KT, Cheng CL. 2012. Nanodiamond for intracellular imaging in the microorganisms in vivo. J Biophoton 5: 838-47.
21. Liu KK, Wang CC, Cheng CL, Chao JI. 2009. Endocytic carboxylated nanodiamond for the labeling and tracking of cell division and differentiation in cancer and stem cells. Biomaterials 30: 4249-59.
22. Liu KK, Zheng WW, Wang CC, Chiu YC, Cheng CL, Lo YS, et al. 2010. Covalent linkage of nanodiamond-paclitaxel for drug delivery and cancer therapy. Nanotechnology 21: 315106: 1-14.
23. Lunov O, Syrovets T, Loos C, Nienhaus GU, Mailander V, Landfester K, et al. 2011. Amino-functionalized polystyrene nanoparticles activate the NLRP3 inflammasome in human macrophages. ACS Nano 5: 9648-57.
24. Mah LJ, El-Osta A, Karagiannis TC. 2010. GammaH2AX: a sensitive molecular marker of DNA damage and repair. Leukemia 24: 679-86.
25. Mohan N, Chen CS, Hsieh HH, Wu YC, Chang HC. 2010. In vivo imaging and toxicity assessments of fluorescent nanodiamonds in Caenorhabditis elegans. Nano Lett 10: 3692-9.
26. Neugart F, Zappe A, Jelezko F, Tietz C, Boudou JP, Krueger A, Wrachtrup J. 2007. Dynamics of diamond nanoparticles in solution and cells. Nano Lett 7: 3588-91.
27. Otero-Gonzalez L, Sierra-Alvarez R, Boitano S, Field JA. 2012. Application and validation of an impedance-based real time cell analyzer to measure the toxicity of nanoparticles impacting human bronchial epithelial cells. Environ Sci Technol 46: 10271-8.
28. Paget V, Sergent J, Chevillard S. 2011. Nano-silicon dioxide toxicological characterization on two human kidney cell lines. J Phys Conf Ser 304: 012080: 1-11.
29. Perevedentseva E, Cheng CY, Chung PH, Tu JS, Hsieh YH, Cheng CL. 2007. The interaction of the protein lysozyme with bacteria E. coli observed using nanodiamond labelling. Nanotechnology 18: 315102: 1-7.
30. Redon CE, Nakamura AJ, Martin OA, Parekh PR, Weyemi US, Bonner WM. 2011. Recent developments in the use of gamma-H2AX as a quantitative DNA double-strand break biomarker. Aging (Albany NY) 3: 168-74.
31. Ruenraroengsak P, Novak P, Berhanu D, Thorley AJ, Valsami-Jones E, Gorelik J, et al. 2012. Respiratory epithelial cytotoxicity and membrane damage (holes) caused by amine-modified nanoparticles. Nanotoxicology 6: 94-108.
32. Schrand AM, Dai L, Schlager JJ, Hussain SM, Osawa E. 2007a. Differential biocompatibility of carbon nanotubes and nanodiamonds. Diamond Relat Mater 16: 2118-23.
33. Schrand AM, Huang H, Carlson C, Schlager JJ, Omacr Sawa E, Hussain SM, Dai L. 2007b. Are diamond nanoparticles cytotoxic? J Phys Chem B 111: 2-7.
34. 2 on human epithelial intestinal HT-29 cell line. Ann Occup Hyg 56: 622-30.
35. Smart DJ, Ahmedi KP, Harvey JS, Lynch AM. 2011. Genotoxicity screening via the gammaH2AX by flow assay. Mutat Res 715: 25-31.
36. Stone V, Johnston H, Schins RP. 2009. Development of in vitro systems for nanotoxicology: methodological considerations. Crit Rev Toxicol 39: 613-26.
37. Vaijayanthimala V, Chang HC. 2009. Functionalized fluorescent nanodiamonds for biomedical applications. Nanomedicine (Lond) 4: 47-55.
38. Vaijayanthimala V, Cheng PY, Yeh SH, Liu KK, Hsiao CH, Chao JI, Chang HC. 2012. The long-term stability and biocompatibility of fluorescent nanodiamond as an in vivo contrast agent. Biomaterials 33: 7794-802.
39. Vaijayanthimala V, Tzeng YK, Chang HC, Li CL. 2009. The biocompatibility of fluorescent nanodiamonds and their mechanism of cellular uptake. Nanotechnology 20: 425103: 1-9.
40. Van Hooijdonk CA, Glade CP, Van Erp PE. 1994. TO-PRO-3 iodide: a novel HeNe laser-excitable DNA stain as an alternative for propidium iodide in multiparameter flow cytometry. Cytometry 17: 185-9.
41. Vial S, Mansuy C, Sagan S, Irinopoulou T, Burlina F, Boudou JP, et al. 2008. Peptide-grafted nanodiamonds: preparation, cytotoxicity and uptake in cells. Chembiochem 9: 2113-9.
42. Wang XZ, Yang Y, Li RF, McGuinnes C, Adamson J, Megson IL, Donaldson K. 2013. Principal component and causal analysis of structural and acute in vitro toxicity data for nanoparticles. Nanotoxicology. doi: 10.3109/17435390.2013. 796534.
43. Xing Y, Xiong W, Zhu L, Osawa E, Hussin S, Dai L. 2011. DNA damage in embryonic stem cells caused by nanodiamonds. ACS Nano 5: 2376-84.
44. Yu SJ, Kang MW, Chang HC, Chen KM, Yu YC. 2005. Bright fluorescent nanodiamonds: no photobleaching and low cytotoxicity. J Am Chem Soc 127: 17604-5.
45. Yuan Y, Wang X, Jia G, Liu J-H, Wang T, Gu Y, et al. 2009. Pulmonary toxicity and translocation of nanodiamonds in mice. Diamond Relat Mater 19: 291-9.
46. Zhang B, Li Y, Fang CY, Chang CC, Chen CS, Chen YY, Chang HC. 2009. Receptor-mediated cellular uptake of folate-conjugated fluorescent nanodiamonds: a combined ensemble and single-particle study. Small 5: 2716-21.
47. Zhang X, Hu W, Li J, Tao L, Wei Y. 2012. A comparative study of cellular uptake and cytotoxicity of multi-walled carbon nanotubes, graphene oxide, and nanodiamond. Toxicol Res 1: 62-8.
48. 2 nanoparticles in cells by flow cytometry. Methods Mol Biol 906: 497-509.
49. 2 nanoparticles in cells by flow cytometry. Cytometry A 77: 677-85.