RAG Represents a Widespread Threat to the Lymphocyte Genome

Cell

Volumn 162, Issue 4, 2015, Pages 751-765

  Teng, Grace ^a   Maman, Yaakov ^a   Resch, Wolfgang ^b   Kim, Min ^c   Yamane, Arito ^b   Qian, Jason ^b   Kieffer Kwon, Kyong Rim ^b   Mandal, Malay ^d   Ji, Yanhong ^e   Meffre, Eric ^a   Clark, Marcus R ^d   Cowell, Lindsay G ^c   Casellas, Rafael ^b   Schatz, David G ^a,f  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^d UNIVERSITY OF CHICAGO   (United States)

^e XI'AN JIAOTONG UNIVERSITY   (China)

^f HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; RAG1 PROTEIN; RAG2 PROTEIN; DNA BINDING PROTEIN; HOMEODOMAIN PROTEIN; RAG-1 PROTEIN; V(D)J RECOMBINATION ACTIVATING PROTEIN 2;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL MATURATION; CHROMATIN; CHROMATIN IMMUNOPRECIPITATION; CHROMOSOME TRANSLOCATION; CONTROLLED STUDY; DNA BINDING; DNA DAMAGE; ENHANCER REGION; EVOLUTIONARY ADAPTATION; GENE REARRANGEMENT; GENOMIC INSTABILITY; HUMAN; HUMAN CELL; LYMPHOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN CLEAVAGE; PROTEIN DEPLETION; REGULATORY MECHANISM; VDJ RECOMBINATION; ANIMAL; CELL LINE; CYTOLOGY; GENE TRANSLOCATION; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE;

ANIMALS; ATAXIA TELANGIECTASIA MUTATED PROTEINS; BASE SEQUENCE; BINDING SITES; CELL LINE; DNA-BINDING PROTEINS; GENOMIC INSTABILITY; HOMEODOMAIN PROTEINS; HUMANS; LYMPHOCYTES; MICE; MOLECULAR SEQUENCE DATA; TRANSLOCATION, GENETIC; V(D)J RECOMBINATION;

EID: 84939167512     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2015.07.009     Document Type: Article

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