Poly(I:C) induced microRNA-146a regulates epithelial barrier and secretion of proinflammatory cytokines in human nasal epithelial cells

European Journal of Pharmacology

Volumn 761, Issue , 2015, Pages 375-382

  Miyata, Ryo ^a   Kakuki, Takuya ^a   Nomura, Kazuaki ^a   Ohkuni, Tsuyoshi ^a   Ogasawara, Noriko ^a   Takano, Ken Ichi ^a   Konno, Takumi ^a   Kohno, Takayuki ^a   Sawada, Norimasa ^a   Himi, Tetsuo ^a   Kojima, Takashi ^a  

^a SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Epithelial barrier; Human nasal epithelial cells; MicroRNA 146a; Poly(I:C); Proinflammatory cytokines; Tight junctions; TLR3; TRAF6

Indexed keywords

CLAUDIN 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; JUNCTIONAL ADHESION MOLECULE A; MICRORNA; MICRORNA 146A; MICRORNA 187; MICRORNA 4274; MICRORNA 4433; MICRORNA 4455; MICRORNA 4750; MICRORNA 4785; MICRORNA 574; OCCLUDIN; PHOSPHATIDYLINOSITOL 3 KINASE; POLYINOSINIC POLYCYTIDYLIC ACID; STRESS ACTIVATED PROTEIN KINASE; TELOMERASE REVERSE TRANSCRIPTASE; TOLL LIKE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; AUTACOID; CYTOKINE; MIRN146 MICRORNA, HUMAN; TELOMERASE; TERT PROTEIN, HUMAN; TIGHT JUNCTION PROTEIN; TLR3 PROTEIN, HUMAN; TOLL LIKE RECEPTOR 3; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6;

ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DOWN REGULATION; EPITHELIUM CELL; HUMAN; HUMAN CELL; HUMAN NASAL EPITHELIAL CELL; HUMAN TISSUE; INFLAMMATION; INNATE IMMUNITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA ANALYSIS; SIGNAL TRANSDUCTION; TIGHT JUNCTION; UPREGULATION; AGONISTS; CELL CULTURE; DRUG EFFECTS; GENETIC TRANSFECTION; GENETICS; IMMUNOLOGY; IMPEDANCE; METABOLISM; NOSE MUCOSA; PERMEABILITY; SECRETION (PROCESS); TIME FACTOR;

CELLS, CULTURED; CYTOKINES; ELECTRIC IMPEDANCE; EPITHELIAL CELLS; HUMANS; IMMUNITY, INNATE; INFLAMMATION MEDIATORS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MICRORNAS; NASAL MUCOSA; NF-KAPPA B; PERMEABILITY; PHOSPHATIDYLINOSITOL 3-KINASE; POLY I-C; SIGNAL TRANSDUCTION; TELOMERASE; TIGHT JUNCTION PROTEINS; TIGHT JUNCTIONS; TIME FACTORS; TNF RECEPTOR-ASSOCIATED FACTOR 6; TOLL-LIKE RECEPTOR 3; TRANSFECTION; UP-REGULATION;

EID: 84938995470     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2015.04.031     Document Type: Article

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