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Volumn 36, Issue 6, 2015, Pages 4453-4459

MiR-511 inhibits growth and metastasis of human hepatocellular carcinoma cells by targeting PIK3R3

Author keywords

Hepatocellular carcinoma; Invasion; miR 511; PIK3R3; Proliferation

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; MICRORNA; MICRORNA 511; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOINOSITIDE 3 KINASE REGULATORY SUBUNIT 3; PROTEIN KINASE B; UNCLASSIFIED DRUG; MIRN511 MICRORNA, HUMAN; MTOR PROTEIN, HUMAN; PIK3R3 PROTEIN, HUMAN; TARGET OF RAPAMYCIN KINASE;

EID: 84938954708     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-015-3085-z     Document Type: Article
Times cited : (38)

References (31)
  • 2
    • 58749107000 scopus 로고    scopus 로고
    • Solitary large hepatocellular carcinoma: a specific subtype of hepatocellular carcinoma with good outcome after hepatic resection
    • PID: 19106686
    • Yang LY, Fang F, Ou DP, Wu W, Zeng ZJ, Wu F. Solitary large hepatocellular carcinoma: a specific subtype of hepatocellular carcinoma with good outcome after hepatic resection. Ann Surg. 2009;249:118–23.
    • (2009) Ann Surg , vol.249 , pp. 118-123
    • Yang, L.Y.1    Fang, F.2    Ou, D.P.3    Wu, W.4    Zeng, Z.J.5    Wu, F.6
  • 3
    • 0347444723 scopus 로고    scopus 로고
    • Micrornas: genomics, biogenesis, mechanism, and function
    • COI: 1:CAS:528:DC%2BD2cXhtVals7o%3D, PID: 14744438
    • Bartel DP. Micrornas: genomics, biogenesis, mechanism, and function. Cell. 2004;116:281–97.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 4
    • 58849112575 scopus 로고    scopus 로고
    • Biogenesis of small RNAs in animals
    • COI: 1:CAS:528:DC%2BD1MXpsVCitA%3D%3D, PID: 19165215
    • Kim VN, Han J, Siomi MC. Biogenesis of small RNAs in animals. Nat Rev Mol Cell Biol. 2009;10:126–39.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 126-139
    • Kim, V.N.1    Han, J.2    Siomi, M.C.3
  • 5
    • 80052451056 scopus 로고    scopus 로고
    • Experimental strategies for microRNA target identification
    • COI: 1:CAS:528:DC%2BC3MXhtFehtr3M, PID: 21652644
    • Thomson DW, Bracken CP, Goodall GJ. Experimental strategies for microRNA target identification. Nucleic Acids Res. 2011;39:6845–53.
    • (2011) Nucleic Acids Res , vol.39 , pp. 6845-6853
    • Thomson, D.W.1    Bracken, C.P.2    Goodall, G.J.3
  • 6
    • 34250201468 scopus 로고    scopus 로고
    • The role of microRNAs in cancer: no small matter
    • COI: 1:CAS:528:DC%2BD2sXmsFKnsr0%3D, PID: 17531469
    • Wiemer EA. The role of microRNAs in cancer: no small matter. Eur J Cancer. 2007;43:1529–44.
    • (2007) Eur J Cancer , vol.43 , pp. 1529-1544
    • Wiemer, E.A.1
  • 10
    • 84907917653 scopus 로고    scopus 로고
    • Hepatitis b virus × protein promotes hepatocellular carcinoma transformation through interleukin-6 activation of microRNA-21 expression
    • COI: 1:CAS:528:DC%2BC2cXhs1Wjs7%2FE, PID: 25087183
    • Li CH, Xu F, Chow S, Feng L, Yin D, Ng TB, et al. Hepatitis b virus × protein promotes hepatocellular carcinoma transformation through interleukin-6 activation of microRNA-21 expression. Eur J Cancer. 2014;50:2560–9.
    • (2014) Eur J Cancer , vol.50 , pp. 2560-2569
    • Li, C.H.1    Xu, F.2    Chow, S.3    Feng, L.4    Yin, D.5    Ng, T.B.6
  • 11
    • 84906267952 scopus 로고    scopus 로고
    • MicroRNA-100 promotes the autophagy of hepatocellular carcinoma cells by inhibiting the expression of mtor and igf-1r
    • PID: 25026290
    • Ge YY, Shi Q, Zheng ZY, Gong J, Zeng C, Yang J, et al. MicroRNA-100 promotes the autophagy of hepatocellular carcinoma cells by inhibiting the expression of mtor and igf-1r. Oncotarget. 2014;5:6218–28.
    • (2014) Oncotarget , vol.5 , pp. 6218-6228
    • Ge, Y.Y.1    Shi, Q.2    Zheng, Z.Y.3    Gong, J.4    Zeng, C.5    Yang, J.6
  • 12
    • 84906262781 scopus 로고    scopus 로고
    • Effects of microRNA-30a on migration, invasion and prognosis of hepatocellular carcinoma
    • COI: 1:CAS:528:DC%2BC2cXhtVOnsbjF, PID: 24954667
    • Liu Z, Tu K, Liu Q. Effects of microRNA-30a on migration, invasion and prognosis of hepatocellular carcinoma. FEBS Lett. 2014;588:3089–97.
    • (2014) FEBS Lett , vol.588 , pp. 3089-3097
    • Liu, Z.1    Tu, K.2    Liu, Q.3
  • 13
    • 84861935924 scopus 로고    scopus 로고
    • MicroRNA-182 downregulates metastasis suppressor 1 and contributes to metastasis of hepatocellular carcinoma
    • COI: 1:CAS:528:DC%2BC3sXitVWgug%3D%3D, PID: 22681717
    • Wang J, Li J, Shen J, Wang C, Yang L, Zhang X. MicroRNA-182 downregulates metastasis suppressor 1 and contributes to metastasis of hepatocellular carcinoma. BMC Cancer. 2012;12:227.
    • (2012) BMC Cancer , vol.12 , pp. 227
    • Wang, J.1    Li, J.2    Shen, J.3    Wang, C.4    Yang, L.5    Zhang, X.6
  • 14
    • 84872150912 scopus 로고    scopus 로고
    • MicroRNA-221 overexpression accelerates hepatocyte proliferation during liver regeneration
    • COI: 1:CAS:528:DC%2BC3sXms12gsQ%3D%3D, PID: 22821679
    • Yuan Q, Loya K, Rani B, Mobus S, Balakrishnan A, Lamle J, et al. MicroRNA-221 overexpression accelerates hepatocyte proliferation during liver regeneration. Hepatology. 2013;57:299–310.
    • (2013) Hepatology , vol.57 , pp. 299-310
    • Yuan, Q.1    Loya, K.2    Rani, B.3    Mobus, S.4    Balakrishnan, A.5    Lamle, J.6
  • 15
    • 84864773072 scopus 로고    scopus 로고
    • MicroRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesis
    • COI: 1:CAS:528:DC%2BC38Xht1SisrjK, PID: 22820290
    • Tsai WC, Hsu SD, Hsu CS, Lai TC, Chen SJ, Shen R, et al. MicroRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesis. J Clin Invest. 2012;122:2884–97.
    • (2012) J Clin Invest , vol.122 , pp. 2884-2897
    • Tsai, W.C.1    Hsu, S.D.2    Hsu, C.S.3    Lai, T.C.4    Chen, S.J.5    Shen, R.6
  • 16
    • 84867163639 scopus 로고    scopus 로고
    • Mir-511 and mir-1297 inhibit human lung adenocarcinoma cell proliferation by targeting oncogene trib2
    • COI: 1:CAS:528:DC%2BC38XhsFaks7rM, PID: 23071539
    • Zhang C, Chi YL, Wang PY, Wang YQ, Zhang YX, Deng J, et al. Mir-511 and mir-1297 inhibit human lung adenocarcinoma cell proliferation by targeting oncogene trib2. PLoS ONE. 2012;7:e46090.
    • (2012) PLoS ONE , vol.7 , pp. 46090
    • Zhang, C.1    Chi, Y.L.2    Wang, P.Y.3    Wang, Y.Q.4    Zhang, Y.X.5    Deng, J.6
  • 17
    • 78449302631 scopus 로고    scopus 로고
    • Deregulation of mir-519a, 153, and 485-5p and its clinicopathological relevance in ovarian epithelial tumours
    • PID: 21083603
    • Kim TH, Kim YK, Kwon Y, Heo JH, Kang H, Kim G, et al. Deregulation of mir-519a, 153, and 485-5p and its clinicopathological relevance in ovarian epithelial tumours. Histopathology. 2010;57:734–43.
    • (2010) Histopathology , vol.57 , pp. 734-743
    • Kim, T.H.1    Kim, Y.K.2    Kwon, Y.3    Heo, J.H.4    Kang, H.5    Kim, G.6
  • 18
    • 72749126286 scopus 로고    scopus 로고
    • Integrative molecular bioinformatics study of human adrenocortical tumors: microRNA, tissue-specific target prediction, and pathway analysis
    • COI: 1:CAS:528:DC%2BD1MXht1GnurbN, PID: 19546168
    • Tombol Z, Szabo PM, Molnar V, Wiener Z, Tolgyesi G, Horanyi J, et al. Integrative molecular bioinformatics study of human adrenocortical tumors: microRNA, tissue-specific target prediction, and pathway analysis. Endocr Relat Cancer. 2009;16:895–906.
    • (2009) Endocr Relat Cancer , vol.16 , pp. 895-906
    • Tombol, Z.1    Szabo, P.M.2    Molnar, V.3    Wiener, Z.4    Tolgyesi, G.5    Horanyi, J.6
  • 19
    • 84860485917 scopus 로고    scopus 로고
    • Mir-138 induces cell cycle arrest by targeting cyclin d3 in hepatocellular carcinoma
    • COI: 1:CAS:528:DC%2BC38Xmt1yisLc%3D, PID: 22362728
    • Wang W, Zhao LJ, Tan YX, Ren H, Qi ZT. Mir-138 induces cell cycle arrest by targeting cyclin d3 in hepatocellular carcinoma. Carcinogenesis. 2012;33:1113–20.
    • (2012) Carcinogenesis , vol.33 , pp. 1113-1120
    • Wang, W.1    Zhao, L.J.2    Tan, Y.X.3    Ren, H.4    Qi, Z.T.5
  • 20
    • 84888005518 scopus 로고    scopus 로고
    • Mir-133a represses tumour growth and metastasis in colorectal cancer by targeting lim and sh3 protein 1 and inhibiting the mapk pathway
    • COI: 1:CAS:528:DC%2BC3sXhtlSiu7jI, PID: 23968734
    • Wang H, An H, Wang B, Liao Q, Li W, Jin X, et al. Mir-133a represses tumour growth and metastasis in colorectal cancer by targeting lim and sh3 protein 1 and inhibiting the mapk pathway. Eur J Cancer. 2013;49:3924–35.
    • (2013) Eur J Cancer , vol.49 , pp. 3924-3935
    • Wang, H.1    An, H.2    Wang, B.3    Liao, Q.4    Li, W.5    Jin, X.6
  • 21
    • 84921508145 scopus 로고    scopus 로고
    • Microrna-331-3p promotes proliferation and metastasis of hepatocellular carcinoma by targeting ph domain and leucine-rich repeat protein phosphatase
    • COI: 1:CAS:528:DC%2BC2cXhs1Wlu77K, PID: 24825302
    • Chang RM, Yang H, Fang F, Xu JF, Yang LY. Microrna-331-3p promotes proliferation and metastasis of hepatocellular carcinoma by targeting ph domain and leucine-rich repeat protein phosphatase. Hepatology. 2014;60:1251–63.
    • (2014) Hepatology , vol.60 , pp. 1251-1263
    • Chang, R.M.1    Yang, H.2    Fang, F.3    Xu, J.F.4    Yang, L.Y.5
  • 22
    • 84871903166 scopus 로고    scopus 로고
    • Microrna-7-regulated tlr9 signaling-enhanced growth and metastatic potential of human lung cancer cells by altering the phosphoinositide-3-kinase, regulatory subunit 3/akt pathway
    • PID: 23135998
    • Xu L, Wen Z, Zhou Y, Liu Z, Li Q, Fei G, et al. Microrna-7-regulated tlr9 signaling-enhanced growth and metastatic potential of human lung cancer cells by altering the phosphoinositide-3-kinase, regulatory subunit 3/akt pathway. Mol Biol Cell. 2013;24:42–55.
    • (2013) Mol Biol Cell , vol.24 , pp. 42-55
    • Xu, L.1    Wen, Z.2    Zhou, Y.3    Liu, Z.4    Li, Q.5    Fei, G.6
  • 23
    • 84905095831 scopus 로고    scopus 로고
    • Microrna as potential biomarker in hcv-associated diffuse large B-cell lymphoma
    • COI: 1:CAS:528:DC%2BC2cXhslOqu77F, PID: 24914240
    • Augello C, Gianelli U, Savi F, Moro A, Bonoldi E, Gambacorta M, et al. Microrna as potential biomarker in hcv-associated diffuse large B-cell lymphoma. J Clin Pathol. 2014;67:697–701.
    • (2014) J Clin Pathol , vol.67 , pp. 697-701
    • Augello, C.1    Gianelli, U.2    Savi, F.3    Moro, A.4    Bonoldi, E.5    Gambacorta, M.6
  • 24
    • 79960691435 scopus 로고    scopus 로고
    • MicroRNA expression profiles of human blood monocyte-derived dendritic cells and macrophages reveal mir-511 as putative positive regulator of toll-like receptor 4
    • COI: 1:CAS:528:DC%2BC3MXpt1Kktbg%3D, PID: 21646346
    • Tserel L, Runnel T, Kisand K, Pihlap M, Bakhoff L, Kolde R, et al. MicroRNA expression profiles of human blood monocyte-derived dendritic cells and macrophages reveal mir-511 as putative positive regulator of toll-like receptor 4. J Biol Chem. 2011;286:26487–95.
    • (2011) J Biol Chem , vol.286 , pp. 26487-26495
    • Tserel, L.1    Runnel, T.2    Kisand, K.3    Pihlap, M.4    Bakhoff, L.5    Kolde, R.6
  • 25
    • 34848891922 scopus 로고    scopus 로고
    • Integrative genomic analysis of phosphatidylinositol 3′-kinase family identifies PIK3R3 as a potential therapeutic target in epithelial ovarian cancer
    • COI: 1:CAS:528:DC%2BD2sXhtVCitL%2FO, PID: 17875760
    • Zhang L, Huang J, Yang N, Greshock J, Liang S, Hasegawa K, et al. Integrative genomic analysis of phosphatidylinositol 3′-kinase family identifies PIK3R3 as a potential therapeutic target in epithelial ovarian cancer. Clin Cancer Res. 2007;13:5314–21.
    • (2007) Clin Cancer Res , vol.13 , pp. 5314-5321
    • Zhang, L.1    Huang, J.2    Yang, N.3    Greshock, J.4    Liang, S.5    Hasegawa, K.6
  • 26
    • 33847647117 scopus 로고    scopus 로고
    • Identification of igf2 signaling through phosphoinositide-3-kinase regulatory subunit 3 as a growth-promoting axis in glioblastoma
    • COI: 1:CAS:528:DC%2BD2sXjtVWltb4%3D, PID: 17360667
    • Soroceanu L, Kharbanda S, Chen R, Soriano RH, Aldape K, Misra A, et al. Identification of igf2 signaling through phosphoinositide-3-kinase regulatory subunit 3 as a growth-promoting axis in glioblastoma. Proc Natl Acad Sci U S A. 2007;104:3466–71.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 3466-3471
    • Soroceanu, L.1    Kharbanda, S.2    Chen, R.3    Soriano, R.H.4    Aldape, K.5    Misra, A.6
  • 27
    • 84864665199 scopus 로고    scopus 로고
    • Genetic and bioinformatic analyses of the expression and function of PI3K regulatory subunit PIK3R3 in an Asian patient gastric cancer library
    • COI: 1:CAS:528:DC%2BC38XhslWjsbbE
    • Zhou J, Chen GB, Tang YC, Sinha RA, Wu Y, Yap CS, et al. Genetic and bioinformatic analyses of the expression and function of PI3K regulatory subunit PIK3R3 in an Asian patient gastric cancer library. BMC Med Genom. 2012;5:34.
    • (2012) BMC Med Genom , vol.5 , pp. 34
    • Zhou, J.1    Chen, G.B.2    Tang, Y.C.3    Sinha, R.A.4    Wu, Y.5    Yap, C.S.6
  • 28
    • 84904204581 scopus 로고    scopus 로고
    • PIK3R3 induces epithelial-to-mesenchymal transition and promotes metastasis in colorectal cancer
    • COI: 1:CAS:528:DC%2BC2cXhtFSmtr7J, PID: 24837077
    • Wang G, Yang X, Li C, Cao X, Luo X, Hu J. PIK3R3 induces epithelial-to-mesenchymal transition and promotes metastasis in colorectal cancer. Mol Cancer Ther. 2014;13:1837–47.
    • (2014) Mol Cancer Ther , vol.13 , pp. 1837-1847
    • Wang, G.1    Yang, X.2    Li, C.3    Cao, X.4    Luo, X.5    Hu, J.6
  • 29
    • 84901801903 scopus 로고    scopus 로고
    • Computational analysis of mRNA expression profiles identifies the ITG family and PIK3R3 as crucial genes for regulating triple negative breast cancer cell migration
    • PID: 24982892
    • Klahan S, Wu MS, Hsi E, Huang CC, Hou MF, Chang WC. Computational analysis of mRNA expression profiles identifies the ITG family and PIK3R3 as crucial genes for regulating triple negative breast cancer cell migration. Biomed Res Int. 2014;2014:536591.
    • (2014) Biomed Res Int , vol.2014 , pp. 536591
    • Klahan, S.1    Wu, M.S.2    Hsi, E.3    Huang, C.C.4    Hou, M.F.5    Chang, W.C.6
  • 30
    • 84900448031 scopus 로고    scopus 로고
    • Phosphorylation and changes in the distribution of nucleolin promote tumor metastasis via the PI3K/AKT pathway in colorectal carcinoma
    • COI: 1:CAS:528:DC%2BC2cXmsVClsro%3D, PID: 24713430
    • Wu DM, Zhang P, Liu RY, Sang YX, Zhou C, Xu GC, et al. Phosphorylation and changes in the distribution of nucleolin promote tumor metastasis via the PI3K/AKT pathway in colorectal carcinoma. FEBS Lett. 2014;588:1921–9.
    • (2014) FEBS Lett , vol.588 , pp. 1921-1929
    • Wu, D.M.1    Zhang, P.2    Liu, R.Y.3    Sang, Y.X.4    Zhou, C.5    Xu, G.C.6
  • 31
    • 85027906125 scopus 로고    scopus 로고
    • MicroRNA-193a-3p and -5p suppress the metastasis of human non-small-cell lung cancer by downregulating the ERBB4/PIK3R3/mTOR/S6K2 signaling pathway
    • Yu T, Li J, Yan M, Liu L, Lin H, Zhao F, Sun L, Zhang Y, Cui Y, Zhang F, He X, Yao M. MicroRNA-193a-3p and -5p suppress the metastasis of human non-small-cell lung cancer by downregulating the ERBB4/PIK3R3/mTOR/S6K2 signaling pathway. Oncogene 2014.
    • (2014) Oncogene
    • Yu, T.1    Li, J.2    Yan, M.3    Liu, L.4    Lin, H.5    Zhao, F.6    Sun, L.7    Zhang, Y.8    Cui, Y.9    Zhang, F.10    He, X.11    Yao, M.12


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