-
2
-
-
28844448182
-
Oncogenic PI3K deregulates transcription and translation
-
DOI 10.1038/nrc1753
-
Oncogenic PI3K deregulates transcription and translation. Bader AG, Kang S, Zhao L, Vogt PK, Nat Rev Cancer 2005 5 12 921 929 10.1038/nrc1753 16341083 (Pubitemid 41766781)
-
(2005)
Nature Reviews Cancer
, vol.5
, Issue.12
, pp. 921-929
-
-
Bader, A.G.1
Kang, S.2
Zhao, L.3
Vogt, P.K.4
-
3
-
-
11144358645
-
High Frequency of Mutations of the PIK3CA Gene in Human Cancers
-
DOI 10.1126/science.1096502
-
High frequency of mutations of the PIK3CA gene in human cancers. Samuels Y, Wang Z, Bardelli A, Silliman N, Ptak J, Szabo S, Yan H, Gazdar A, Powell SM, Riggins GJ, et al. Science 2004 304 5670 554 10.1126/science.1096502 15016963 (Pubitemid 38541907)
-
(2004)
Science
, vol.304
, Issue.5670
, pp. 554
-
-
Samuels, Y.1
Wang, Z.2
Bardelli, A.3
Silliman, N.4
Ptak, J.5
Szabo, S.6
Yan, H.7
Gazdar, A.8
Powell, S.M.9
Riggins, G.J.10
Willson, J.K.V.11
Markowitz, S.12
Kinzler, K.W.13
Vogelstein, B.14
Velculescu, V.E.15
-
4
-
-
51349148948
-
PTEN-deficient cancers depend on PIK3CB
-
10.1073/pnas.0802655105 18755892
-
PTEN-deficient cancers depend on PIK3CB. Wee S, Wiederschain D, Maira SM, Loo A, Miller C, deBeaumont R, Stegmeier F, Yao YM, Lengauer C, Proc Natl Acad Sci USA 2008 105 35 13057 13062 10.1073/pnas.0802655105 18755892
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, Issue.35
, pp. 13057-13062
-
-
Wee, S.1
Wiederschain, D.2
Maira, S.M.3
Loo, A.4
Miller, C.5
Debeaumont, R.6
Stegmeier, F.7
Yao, Y.M.8
Lengauer, C.9
-
5
-
-
33750459743
-
A selective inhibitor of the p110δ isoform of PI 3-kinase inhibits AML cell proliferation and survival and increases the cytotoxic effects of VP16
-
DOI 10.1038/sj.onc.1209670, PII 1209670
-
A selective inhibitor of the p110delta isoform of PI 3-kinase inhibits AML cell proliferation and survival and increases the cytotoxic effects of VP16. Billottet C, Grandage VL, Gale RE, Quattropani A, Rommel C, Vanhaesebroeck B, Khwaja A, Oncogene 2006 25 50 6648 6659 10.1038/sj.onc.1209670 16702948 (Pubitemid 44646192)
-
(2006)
Oncogene
, vol.25
, Issue.50
, pp. 6648-6659
-
-
Billottet, C.1
Grandage, V.L.2
Gale, R.E.3
Quattropani, A.4
Rommel, C.5
Vanhaesebroeck, B.6
Khwaja, A.7
-
6
-
-
33746257209
-
The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism
-
DOI 10.1038/nrg1879, PII NRG1879
-
The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism. Engelman JA, Luo J, Cantley LC, Nat Rev Genet 2006 7 8 606 619 10.1038/nrg1879 16847462 (Pubitemid 44100518)
-
(2006)
Nature Reviews Genetics
, vol.7
, Issue.8
, pp. 606-619
-
-
Engelman, J.A.1
Luo, J.2
Cantley, L.C.3
-
7
-
-
70749140937
-
Somatic mutations in p85alpha promote tumorigenesis through class IA PI3K activation
-
10.1016/j.ccr.2009.10.016 19962665
-
Somatic mutations in p85alpha promote tumorigenesis through class IA PI3K activation. Jaiswal BS, Janakiraman V, Kljavin NM, Chaudhuri S, Stern HM, Wang W, Kan Z, Dbouk HA, Peters BA, Waring P, et al. Cancer Cell 2009 16 6 463 474 10.1016/j.ccr.2009.10.016 19962665
-
(2009)
Cancer Cell
, vol.16
, Issue.6
, pp. 463-474
-
-
Jaiswal, B.S.1
Janakiraman, V.2
Kljavin, N.M.3
Chaudhuri, S.4
Stern, H.M.5
Wang, W.6
Kan, Z.7
Dbouk, H.A.8
Peters, B.A.9
Waring, P.10
-
8
-
-
79958820962
-
PIK3R1 (p85alpha) is somatically mutated at high frequency in primary endometrial cancer
-
10.1158/0008-5472.CAN-11-0549 21478295
-
PIK3R1 (p85alpha) is somatically mutated at high frequency in primary endometrial cancer. Urick ME, Rudd ML, Godwin AK, Sgroi D, Merino M, Bell DW, Cancer Res 2011 71 12 4061 4067 10.1158/0008-5472.CAN-11-0549 21478295
-
(2011)
Cancer Res
, vol.71
, Issue.12
, pp. 4061-4067
-
-
Urick, M.E.1
Rudd, M.L.2
Godwin, A.K.3
Sgroi, D.4
Merino, M.5
Bell, D.W.6
-
9
-
-
33847647117
-
Identification of IGF2 signaling through phosphoinositide-3-kinase regulatory subunit 3 as a growth-promoting axis in glioblastoma
-
DOI 10.1073/pnas.0611271104
-
Identification of IGF2 signaling through phosphoinositide-3-kinase regulatory subunit 3 as a growth-promoting axis in glioblastoma. Soroceanu L, Kharbanda S, Chen R, Soriano RH, Aldape K, Misra A, Zha J, Forrest WF, Nigro JM, Modrusan Z, et al. Proc Natl Acad Sci USA 2007 104 9 3466 3471 10.1073/pnas.0611271104 17360667 (Pubitemid 46364182)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.9
, pp. 3466-3471
-
-
Soroceanu, L.1
Kharbanda, S.2
Chen, R.3
Soriano, R.H.4
Aldape, K.5
Misra, A.6
Zha, J.7
Forrest, W.F.8
Nigro, J.M.9
Modrusan, Z.10
Feuerstein, B.G.11
Phillips, H.S.12
-
10
-
-
34848891922
-
Integrative genomic analysis of phosphatidylinositol 3′-kinase family identifies PIK3R3 as a potential therapeutic target in epithelial ovarian cancer
-
DOI 10.1158/1078-0432.CCR-06-2660
-
Integrative genomic analysis of phosphatidylinositol 3'-kinase family identifies PIK3R3 as a potential therapeutic target in epithelial ovarian cancer. Zhang L, Huang J, Yang N, Greshock J, Liang S, Hasegawa K, Giannakakis A, Poulos N, O'Brien-Jenkins A, Katsaros D, et al. Clin Cancer Res 2007 13 18 Pt 1 5314 5321 17875760 (Pubitemid 47510355)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.18
, pp. 5314-5321
-
-
Zhang, L.1
Huang, J.2
Yang, N.3
Greshock, J.4
Liang, S.5
Hasegawa, K.6
Giannakakis, A.7
Poulos, N.8
O'Brien-Jenkins, A.9
Katsaros, D.10
Butzow, R.11
Weber, B.L.12
Coukos, G.13
-
11
-
-
25644461068
-
International lung cancer trends by histologic type: Male:female differences diminishing and adenocarcinoma rates rising
-
DOI 10.1002/ijc.21183
-
International lung cancer trends by histologic type: male:female differences diminishing and adenocarcinoma rates rising. Devesa SS, Bray F, Vizcaino AP, Parkin DM, Int J Cancer 2005 117 2 294 299 10.1002/ijc.21183 15900604 (Pubitemid 41379403)
-
(2005)
International Journal of Cancer
, vol.117
, Issue.2
, pp. 294-299
-
-
Devesa, S.S.1
Bray, F.2
Vizcaino, A.P.3
Parkin, D.M.4
-
12
-
-
0034811794
-
Recent advances in the treatment of gastric cancer
-
Recent advances in the treatment of gastric cancer. Sun W, Haller DG, Drugs 2001 61 11 1545 1551 10.2165/00003495-200161110-00002 11577792 (Pubitemid 32905276)
-
(2001)
Drugs
, vol.61
, Issue.11
, pp. 1545-1551
-
-
Sun, W.1
Haller, D.G.2
-
13
-
-
0033981397
-
Recurrence following curative resection for gastric carcinoma
-
DOI 10.1046/j.1365-2168.2000.01360.x
-
Recurrence following curative resection for gastric carcinoma. Yoo CH, Noh SH, Shin DW, Choi SH, Min JS, Br J Surg 2000 87 2 236 242 10.1046/j.1365-2168.2000.01360.x 10671934 (Pubitemid 30088655)
-
(2000)
British Journal of Surgery
, vol.87
, Issue.2
, pp. 236-242
-
-
Yoo, C.H.1
Noh, S.H.2
Shin, D.W.3
Choi, S.H.4
Min, J.S.5
-
14
-
-
33846457870
-
Cancer statistics, 2007
-
Cancer statistics, 2007. Jemal A, Siegel R, Ward E, Murray T, Xu J, Thun MJ, CA Cancer J Clin 2007 57 1 43 66 10.3322/canjclin.57.1.43 17237035 (Pubitemid 46148091)
-
(2007)
Ca-A Cancer Journal for Clinicians
, vol.57
, Issue.1
, pp. 43-66
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Murray, T.4
Xu, J.5
Thun, M.J.6
-
15
-
-
0032932080
-
Expression of the E2F family in human gastrointestinal carcinomas
-
DOI 10.1002/(SICI)1097-0215(19990517)81:4<535::AID-IJC5>3.0.CO;2-4
-
Expression of the E2F family in human gastrointestinal carcinomas. Suzuki T, Yasui W, Yokozaki H, Naka K, Ishikawa T, Tahara E, Int J Cancer 1999 81 4 535 538 10.1002/(SICI)1097-0215(19990517)81:4<535::AID-IJC5>3.0.CO;2-4 10225440 (Pubitemid 29203048)
-
(1999)
International Journal of Cancer
, vol.81
, Issue.4
, pp. 535-538
-
-
Suzuki, T.1
Yasui, W.2
Yokozaki, H.3
Naka, K.4
Ishikawa, T.5
Tahara, E.6
-
16
-
-
0037050745
-
K-ras mutation in Helicobacter pylori-associated chronic gastritis in patients with and without gastric cancer
-
DOI 10.1002/ijc.1644
-
K-ras mutation in helicobacter pylori-associated chronic gastritis in patients with and without gastric cancer. Hiyama T, Haruma K, Kitadai Y, Masuda H, Miyamoto M, Tanaka S, Yoshihara M, Shimamoto F, Chayama K, Int J Cancer 2002 97 5 562 566 10.1002/ijc.1644 11807778 (Pubitemid 34087791)
-
(2002)
International Journal of Cancer
, vol.97
, Issue.5
, pp. 562-566
-
-
Hiyama, T.1
Haruma, K.2
Kitadai, Y.3
Masuda, H.4
Miyamoto, M.5
Tanaka, S.6
Yoshihara, M.7
Shimamoto, F.8
Chayama, K.9
-
17
-
-
27944468211
-
Nuclear translocations of β-catenin and TCF4 in gastric cancers correlate with lymph node metastasis but probably not with CD44 expression
-
DOI 10.1016/j.humpath.2005.09.003, PII S0046817705004661
-
Nuclear translocations of beta-catenin and TCF4 in gastric cancers correlate with lymph node metastasis but probably not with CD44 expression. Chen XY, Wang ZC, Li H, Cheng XX, Sun Y, Wang XW, Wu ML, Liu J, Hum Pathol 2005 36 12 1294 1301 16311123 (Pubitemid 41682285)
-
(2005)
Human Pathology
, vol.36
, Issue.12
, pp. 1294-1301
-
-
Chen, X.-Y.1
Wang, Z.-C.2
Li, H.3
Cheng, X.-X.4
Sun, Y.5
Wang, X.-W.6
Wu, M.-L.7
Liu, J.8
-
18
-
-
3543105225
-
Circular binary segmentation for the analysis of array-based DNA copy number data
-
DOI 10.1093/biostatistics/kxh008
-
Circular binary segmentation for the analysis of array-based DNA copy number data. Olshen AB, Venkatraman ES, Lucito R, Wigler M, Biostatistics 2004 5 4 557 572 10.1093/biostatistics/kxh008 15475419 (Pubitemid 41180205)
-
(2004)
Biostatistics
, vol.5
, Issue.4
, pp. 557-572
-
-
Olshen, A.B.1
Venkatraman, E.S.2
Lucito, R.3
Wigler, M.4
-
19
-
-
38049100456
-
Assessing the significance of chromosomal aberrations in cancer: Methodology and application to glioma
-
10.1073/pnas.0710052104 18077431
-
Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma. Beroukhim R, Getz G, Nghiemphu L, Barretina J, Hsueh T, Linhart D, Vivanco I, Lee JC, Huang JH, Alexander S, et al. Proc Natl Acad Sci USA 2007 104 50 20007 20012 10.1073/pnas.0710052104 18077431
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.50
, pp. 20007-20012
-
-
Beroukhim, R.1
Getz, G.2
Nghiemphu, L.3
Barretina, J.4
Hsueh, T.5
Linhart, D.6
Vivanco, I.7
Lee, J.C.8
Huang, J.H.9
Alexander, S.10
-
20
-
-
59049096397
-
Strain-induced proliferation requires the phosphatidylinositol 3-kinase/AKT/glycogen synthase kinase pathway
-
19047055
-
Strain-induced proliferation requires the phosphatidylinositol 3-kinase/AKT/glycogen synthase kinase pathway. Gayer CP, Chaturvedi LS, Wang S, Craig DH, Flanigan T, Basson MD, J Biol Chem 2009 284 4 2001 2011 19047055
-
(2009)
J Biol Chem
, vol.284
, Issue.4
, pp. 2001-2011
-
-
Gayer, C.P.1
Chaturvedi, L.S.2
Wang, S.3
Craig, D.H.4
Flanigan, T.5
Basson, M.D.6
-
21
-
-
40349094835
-
1 integrin and inhibits adhesion of MDA-MB-435 cells to fibronectin via reactive oxygen species signaling
-
DOI 10.1158/1541-7786.MCR-07-0197
-
Salvicine inactivates beta 1 integrin and inhibits adhesion of MDA-MB-435 cells to fibronectin via reactive oxygen species signaling. Zhou J, Chen Y, Lang JY, Lu JJ, Ding J, Mol Cancer Res 2008 6 2 194 204 10.1158/1541-7786.MCR- 07-0197 18314480 (Pubitemid 351342407)
-
(2008)
Molecular Cancer Research
, vol.6
, Issue.2
, pp. 194-204
-
-
Zhou, J.1
Chen, Y.2
Lang, J.-Y.3
Lu, J.-J.4
Ding, J.5
-
22
-
-
42249098858
-
Genes involved in cell adhesion, cell motility and mitogenic signaling are altered due to HPV 16 E5 protein expression
-
DOI 10.1038/sj.onc.1210916, PII 1210916
-
Genes involved in cell adhesion, cell motility and mitogenic signaling are altered due to HPV 16 E5 protein expression. Kivi N, Greco D, Auvinen P, Auvinen E, Oncogene 2008 27 18 2532 2541 10.1038/sj.onc.1210916 17982485 (Pubitemid 351550881)
-
(2008)
Oncogene
, vol.27
, Issue.18
, pp. 2532-2541
-
-
Kivi, N.1
Greco, D.2
Auvinen, P.3
Auvinen, E.4
-
23
-
-
4143050198
-
Platelet-derived growth factor stimulates membrane lipid synthesis through activation of phosphatidylinositol 3-kinase and sterol regulatory element-binding proteins
-
DOI 10.1074/jbc.M405924200
-
Platelet-derived growth factor stimulates membrane lipid synthesis through activation of phosphatidylinositol 3-kinase and sterol regulatory element-binding proteins. Demoulin JB, Ericsson J, Kallin A, Rorsman C, Ronnstrand L, Heldin CH, J Biol Chem 2004 279 34 35392 35402 10.1074/jbc.M405924200 15213220 (Pubitemid 39100539)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.34
, pp. 35392-35402
-
-
Demoulin, J.-B.1
Ericsson, J.2
Kallin, A.3
Rorsman, C.4
Ronnstrand, L.5
Heldin, C.-H.6
-
24
-
-
34548181395
-
SREBP-1 regulates the expression of heme oxygenase 1 and the phosphatidylinositol-3 kinase regulatory subunit p55γ
-
DOI 10.1194/jlr.M700136-JLR200
-
SREBP-1 regulates the expression of heme oxygenase 1 and the phosphatidylinositol-3 kinase regulatory subunit p55 gamma. Kallin A, Johannessen LE, Cani PD, Marbehant CY, Essaghir A, Foufelle F, Ferre P, Heldin CH, Delzenne NM, Demoulin JB, J Lipid Res 2007 48 7 1628 1636 10.1194/jlr.M700136-JLR200 17452746 (Pubitemid 47312024)
-
(2007)
Journal of Lipid Research
, vol.48
, Issue.7
, pp. 1628-1636
-
-
Kallin, A.1
Johannessen, L.E.2
Cani, P.D.3
Marbehant, C.Y.4
Essaghir, A.5
Foufelle, F.6
Ferre, P.7
Heldin, C.-H.8
Delzenne, N.M.9
Demoulin, J.-B.10
-
25
-
-
33644820339
-
Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis
-
DOI 10.1016/j.ccr.2006.02.019, PII S1535610806000560
-
Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis. Phillips HS, Kharbanda S, Chen R, Forrest WF, Soriano RH, Wu TD, Misra A, Nigro JM, Colman H, Soroceanu L, et al. Cancer Cell 2006 9 3 157 173 10.1016/j.ccr.2006. 02.019 16530701 (Pubitemid 43357943)
-
(2006)
Cancer Cell
, vol.9
, Issue.3
, pp. 157-173
-
-
Phillips, H.S.1
Kharbanda, S.2
Chen, R.3
Forrest, W.F.4
Soriano, R.H.5
Wu, T.D.6
Misra, A.7
Nigro, J.M.8
Colman, H.9
Soroceanu, L.10
Williams, P.M.11
Modrusan, Z.12
Feuerstein, B.G.13
Aldape, K.14
-
26
-
-
0028982198
-
The structure and function of p55PIK reveal a new regulatory subunit for phosphatidylinositol 3-kinase
-
7542745
-
The structure and function of p55PIK reveal a new regulatory subunit for phosphatidylinositol 3-kinase. Pons S, Asano T, Glasheen E, Miralpeix M, Zhang Y, Fisher TL, Myers MG, Sun XJ, White MF, Mol Cell Biol 1995 15 8 4453 4465 7542745
-
(1995)
Mol Cell Biol
, vol.15
, Issue.8
, pp. 4453-4465
-
-
Pons, S.1
Asano, T.2
Glasheen, E.3
Miralpeix, M.4
Zhang, Y.5
Fisher, T.L.6
Myers, M.G.7
Sun, X.J.8
White, M.F.9
-
27
-
-
0037369896
-
The N-terminal 24 amino acids of the p55 gamma regulatory subunit of phosphoinositide 3-kinase binds Rb and induces cell cycle arrest
-
DOI 10.1128/MCB.23.5.1717-1725.2003
-
The N-terminal 24 amino acids of the p55 gamma regulatory subunit of phosphoinositide 3-kinase binds Rb and induces cell cycle arrest. Xia X, Cheng A, Akinmade D, Hamburger AW, Mol Cell Biol 2003 23 5 1717 1725 10.1128/MCB.23.5.1717-1725.2003 12588990 (Pubitemid 36246052)
-
(2003)
Molecular and Cellular Biology
, vol.23
, Issue.5
, pp. 1717-1725
-
-
Xia, X.1
Cheng, A.2
Akinmade, D.3
Hamburger, A.W.4
-
28
-
-
21444444602
-
Overexpression of the N-terminal end of the p55gamma regulatory subunit of phosphatidylinositol 3-kinase blocks cell cycle progression in gastric carcinoma cells
-
15809724
-
Overexpression of the N-terminal end of the p55gamma regulatory subunit of phosphatidylinositol 3-kinase blocks cell cycle progression in gastric carcinoma cells. Hu J, Liu S, Wang J, Luo X, Gao X, Xia X, Feng Y, Tao D, Wang G, Li X, et al. Int J Oncol 2005 26 5 1321 1327 15809724
-
(2005)
Int J Oncol
, vol.26
, Issue.5
, pp. 1321-1327
-
-
Hu, J.1
Liu, S.2
Wang, J.3
Luo, X.4
Gao, X.5
Xia, X.6
Feng, Y.7
Tao, D.8
Wang, G.9
Li, X.10
-
29
-
-
57749095656
-
A peptide inhibitor derived from p55PIK phosphatidylinositol 3-kinase regulatory subunit: A novel cancer therapy
-
10.1158/1535-7163.MCT-08-0499 19074847
-
A peptide inhibitor derived from p55PIK phosphatidylinositol 3-kinase regulatory subunit: a novel cancer therapy. Hu J, Xia X, Cheng A, Wang G, Luo X, Reed MF, Fojo T, Oetting A, Gong J, Yen PM, Mol Cancer Ther 2008 7 12 3719 3728 10.1158/1535-7163.MCT-08-0499 19074847
-
(2008)
Mol Cancer Ther
, vol.7
, Issue.12
, pp. 3719-3728
-
-
Hu, J.1
Xia, X.2
Cheng, A.3
Wang, G.4
Luo, X.5
Reed, M.F.6
Fojo, T.7
Oetting, A.8
Gong, J.9
Yen, P.M.10
|