Effects of microRNA-30a on migration, invasion and prognosis of hepatocellular carcinoma

FEBS Letters

Volumn 588, Issue 17, 2014, Pages 3089-3097

  Liu, Zhaoyang ^a   Tu, Kangsheng ^a   Liu, Qingguang ^a  

^a THE FIRST AFFILIATED HOSPITAL OF XI AN JIAOTONG UNIVERSITY   (China)

Author keywords

EMT; HCC; MicroRNA 30a; SNAI1

Indexed keywords

MICRORNA; MICRORNA 30A; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SNAI1; UNCLASSIFIED DRUG;

ARTICLE; CANCER GROWTH; CANCER PROGNOSIS; CELL INVASION; CELL MIGRATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DISEASE FREE SURVIVAL; DOWN REGULATION; EPITHELIAL MESENCHYMAL TRANSITION; GAIN OF FUNCTION MUTATION; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE INTERACTION; GENE LOCATION; GENE TARGETING; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER CELL CARCINOMA; LOSS OF FUNCTION MUTATION; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROTEIN RNA BINDING; RNA ANALYSIS; RNA GENE; TISSUE DISTRIBUTION; TRANSCRIPTION REGULATION; TUMOR CELL;

EMT; HCC; MICRORNA-30A; SNAI1;

ADULT; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL MOVEMENT; DISEASE-FREE SURVIVAL; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LIVER NEOPLASMS; MALE; MICRORNAS; NEOPLASM INVASIVENESS; TRANSCRIPTION FACTORS;

EID: 84906262781     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2014.06.037     Document Type: Article

References (28)

1. D.M. Parkin, F. Bray, J. Ferlay, and P. Pisani Global cancer statistics CA Cancer J. Clin. 55 2005 2002 74 108
2. L.R. Roberts, and G.J. Gores Hepatocellular carcinoma: molecular pathways and new therapeutic targets Semin. Liver Dis. 25 2005 212 225
3. R.N. Aravalli, C.J. Steer, and E.N. Cressman Molecular mechanisms of hepatocellular carcinoma Hepatology 48 2008 2047 2063
4. J. Jiang, Y. Gusev, L. Aderca, T.A. Mettler, D.M. Nagorney, and D.J. Brackett et al. Association of microRNA expression in hepatocellular carcinomas with hepatitis infection, cirrhosis, and patient survival Clin. Cancer Res. 14 2008 419 427
5. Y. Murakami, T. Yasuda, K. Saigo, T. Urashima, H. Toyoda, and T. Okanoue et al. Comprehensive analysis of microRNA expression patterns in hepatocellular carcinoma and non-tumorous tissues Oncogene 25 2006 2537 2545
6. Y. Ladeiro, G. Couchy, C. Balabaud, P. Bioulac-Sage, L. Pelletier, and S. Rebouissou et al. MicroRNA profiling in hepatocellular tumors is associated with clinical features and oncogene/tumor suppressor gene mutations Hepatology 47 2008 1955 1963
7. A. Budhu, H.L. Jia, M. Forgues, C.G. Liu, D. Goldstein, and A. Lam et al. Identification of metastasis-related microRNAs in hepatocellular carcinoma Hepatology 47 2008 897 907
8. H. Su, J.R. Yang, T. Xu, J. Huang, L. Xu, and Y. Yuan et al. MicroRNA-101, down-regulated in hepatocellular carcinoma, promotes apoptosis and suppresses tumorigenicity Cancer Res. 69 2009 1135 1142
9. A. Budhu, H.L. Jia, and M. Forgues et al. Identification of metastasis-related microRNAs in hepatocellular carcinoma Hepatology 47 2008 897 907
10. J. Braun, C. Hoang, and H. Dralle et al. Downregulation of microRNAs directs the EMT and invasive potential of anaplastic thyroid carcinomas Oncogene 29 2010 4237 4244
11. C.W. Cheng, H.W. Wang, and C.W. Chang et al. MicroRNA-30a inhibits cell migration and invasion by downregulating vimentin expression and is a potential prognostic marker in breast cancer Breast Cancer Res. Treat. 134 2012 1081 1093
12. M. Ksiazkiewicz, A. Markiewicz, and A.J. Zaczek Epithelial-mesenchymal transition: a hallmark in metastasis formation linking circulating tumor cells and cancer stem cells Pathobiology 79 2012 195 208
13. M. Zeisberg, and E.G. Neilson Biomarkers for epithelial-mesenchymal transitions J. Clin. Invest. 119 2009 1429 1437
14. T. Brabletz To differentiate or not - routes towards metastasis Nat. Rev. Cancer 12 2012 425 436
15. J.M. Lee, S. Dedhar, and R. Kalluri The epithelial-mesenchymal transition: new insights in signaling, development, and disease J. Cell Biol. 172 2006 973 981
16. H. Peinado et al. Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? Nat. Rev. Cancer 7 2007 415 428
17. H. Peinado, D. Olmeda, and A. Cano Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? Nat. Rev. Cancer 7 2007 415 428
18. W. Ma, C.C. Wong, E.K. Tung, C.M. Wong, and I.O. Ng RhoE is frequently downregulated in HCC and suppresses HCC invasion through antagonizing the Rho/ROCK/MYPT pathway Hepatology 57 2012 152 161
19. S.K. Pavelic, M. Sedic, and S. Bosnjak Metastasis: new perspectives on an old problem Mol. Cancer 10 2011 22
20. M. Garofalo, and C.M. Croce microRNAs: master regulators as potential therapeutics in cancer Annu. Rev. Pharmacol. Toxicol. 51 2011 25 43
21. M.V. Iorio, and C.M. Croce microRNA involvement in human cancer Carcinogenesis 33 2012 1126 1133
22. J. Lu, G. Getz, E.A. Miska, E. Alvarez-Saavedra, J. Lamb, and D. Peck et al. MicroRNA expression profiles classify human cancers Nature 435 2005 834 838
23. F. Meng, R. Henson, H. Wehbe-Janek, K. Ghoshal, S.T. Jacob, and T. Patel MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer Gastroenterology 133 2007 647 658
24. S. Volinia, G.A. Calin, C.G. Liu, S. Ambs, A. Cimmino, and F. Petrocca et al. A microRNA expression signature of human solid tumors defines cancer gene targets Proc. Natl. Acad. Sci. U.S.A. 103 2006 2257 2261
25. M.D. Bullock et al. MicroRNAs: critical regulators of epithelial to mesenchymal (EMT) and mesenchymal to epithelial transition (MET) in cancer progression Biol. Cell 104 2012 3 12
26. Q. Xu, Q. Sun, J.J. Zhang, and J.S. Yu et al. Downregulation of miR-153 contributes to epithelial-mesenchymal transition and tumor metastasis in human epithelial cancer Carcinogenesis 34 2013 539 549
27. E. Batlle, E. Sancho, and C. Franci et al. The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells Nat. Cell Biol. 2 2000 84 89
28. L. Larue et al. Epithelial-mesenchymal transition in development and cancer: role of phosphatidylinositol 3′ kinase/AKT pathways Oncogene 24 2005 7443 7454