An Umpolung Approach for the Chemoselective Arylation of Selenocysteine in Unprotected Peptides

Journal of the American Chemical Society

Volumn 137, Issue 31, 2015, Pages 9784-9787

  Cohen, Daniel T ^a   Zhang, Chi ^a   Pentelute, Bradley L ^a   Buchwald, Stephen L ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ORGANIC COMPOUNDS; PEPTIDES;

ARYLBORONIC ACIDS; BIO-CONJUGATION; CHEMOSELECTIVE; ELECTROPHILIC CHARACTER; EXPERIMENTAL EVIDENCE; OXIDATIVE CONDITIONS; SELENOCYSTEINE; SIMPLE APPROACH;

AROMATIC COMPOUNDS;

ARYLBORONIC ACID; BORONIC ACID DERIVATIVE; PEPTIDE; SELENOCYSTEINE; UNCLASSIFIED DRUG; AROMATIC HYDROCARBON;

ARTICLE; ARYLATION; CHEMICAL BOND; CONJUGATION; ELECTROPHILICITY; ION CURRENT; NUCLEOPHILICITY; OXIDATION;

BORONIC ACIDS; HYDROCARBONS, AROMATIC; PEPTIDES; SELENOCYSTEINE;

EID: 84938945424     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/jacs.5b05447     Document Type: Article

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