Antibody conjugation via one and two C-terminal selenocysteines

Methods

Volumn 65, Issue 1, 2014, Pages 133-138

  Li, Xiuling ^a   Yang, Jiahui ^b   Rader, Christoph ^a,b  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Antibody conjugation; Antibody engineering; Selenocysteine

Indexed keywords

ANTIBODY CONJUGATE; IODOACETAMIDE; SELENOCYSTEINE;

ANTIBODY CONJUGATION; ANTIBODY ENGINEERING; ANTIGEN BINDING; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONJUGATION; GENETIC ENGINEERING; HUMAN; HUMAN CELL; PRIORITY JOURNAL; STOICHIOMETRY;

ANTIBODY CONJUGATION; ANTIBODY ENGINEERING; SELENOCYSTEINE;

ANIMALS; ANTIBODIES, MONOCLONAL; CLONING, MOLECULAR; DRUG CARRIERS; HEK293 CELLS; HUMANS; PROTEIN BINDING; PROTEIN ENGINEERING; SELENOCYSTEINE;

EID: 84891626541     PISSN: 10462023     EISSN: 10959130     Source Type: Journal    
DOI: 10.1016/j.ymeth.2013.05.023     Document Type: Article

References (17)

1. Scott A.M., Wolchok J.D., Old L.J. Nat. Rev. Cancer 2012, 12:278-287.
2. Hamblett K.J., Senter P.D., Chace D.F., Sun M.M., Lenox J., Cerveny C.G., Kissler K.M., Bernhardt S.X., Kopcha A.K., Zabinski R.F., Meyer D.L., Francisco J.A. Clin. Cancer Res. 2004, 10:7063-7070.
3. Wang L., Amphlett G., Blattler W.A., Lambert J.M., Zhang W. Protein Sci. 2005, 14:2436-2446.
4. Junutula J.R., Raab H., Clark S., Bhakta S., Leipold D.D., Weir S., Chen Y., Simpson M., Tsai S.P., Dennis M.S., Lu Y., Meng Y.G., Ng C., Yang J., Lee C.C., Duenas E., Gorrell J., Katta V., Kim A., McDorman K., Flagella K., Venook R., Ross S., Spencer S.D., Lee Wong W., Lowman H.B., Vandlen R., Sliwkowski M.X., Scheller R.H., Polakis P., Mallet W. Nat. Biotechnol. 2008, 26:925-932.
5. Hofer T., Thomas J.D., Burke T.R., Rader C. Proc. Natl. Acad. Sci. USA 2008, 105:12451-12456.
6. Hofer T., Skeffington L.R., Chapman C.M., Rader C. Biochemistry 2009, 48:12047-12057.
7. Cui H., Thomas J.D., Burke T.R., Rader C. J. Biol. Chem. 2012, 287:28206-28214.
8. Thomas J.D., Cui H., North P.J., Hofer T., Rader C., Burke T.R. Bioconjugate Chem. 2012, 23:2007-2013.
9. Thomas J.D., Hofer T., Rader C., Burke T.R. Bioorg. Med. Chem. Lett. 2008, 18:5785-5788.
10. Hatfield D.L., Gladyshev V.N. Mol. Cell. Biol. 2002, 22:3565-3576.
11. Lobanov A.V., Turanov A.A., Hatfield D.L., Gladyshev V.N. Crit. Rev. Biochem. Mol. Biol. 2010, 45:257-265.
12. Yang J., Baskar S., Kwong K.Y., Kennedy M.G., Wiestner A., Rader C. PloS One 2011, 6:e21018.
13. Yang J., Rader C. Methods Mol. Biol. 2012, 901:209-232.
14. Lee B.C., Lobanov A.V., Marino S.M., Kaya A., Seravalli J., Hatfield D.L., Gladyshev V.N. J. Biol. Chem. 2011, 286:18747-18755.
15. Hill K.E., Lloyd R.S., Burk R.F. Proc. Natl. Acad. Sci. USA 1993, 90:537-541.
16. Shchedrina V.A., Novoselov S.V., Malinouski M.Y., Gladyshev V.N. Proc. Natl. Acad. Sci. USA 2007, 104:13919-13924.
17. Besse D., Siedler F., Diercks T., Kessler H., Moroder L. Angew. Chem. Int. Ed. Engl. 1997, 36:883-885.