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Volumn 68, Issue 5, 2016, Pages 634-645

Mesoporous silica-based dosage forms improve release characteristics of poorly soluble drugs: Case example fenofibrate

Author keywords

biorelevant media; dissolution; fenofibrate; mesoporous silica; poorly soluble drugs

Indexed keywords

BIMODAL POROUS SILICA; FENOFIBRATE; HYDROXYPROPYLMETHYLCELLULOSE ACETATE SUCCINATE; MONOMODAL POROUS SILICA; POVIDONE; SILICON DIOXIDE; UNCLASSIFIED DRUG; ANTILIPEMIC AGENT; DELAYED RELEASE FORMULATION; HYDROXYPROPYLMETHYLCELLULOSE; METHYLCELLULOSE; NANOPARTICLE; POLY(VINYLPYRROLIDONE-CO-VINYL-ACETATE); PYRROLIDINE DERIVATIVE; VINYL DERIVATIVE;

EID: 84938843860     PISSN: 00223573     EISSN: 20427158     Source Type: Journal    
DOI: 10.1111/jphp.12465     Document Type: Article
Times cited : (13)

References (15)
  • 1
    • 84855874314 scopus 로고    scopus 로고
    • Use of ordered mesoporous silica to enhance the oral bioavailability of ezetimibe in dogs
    • Kiekens F, et al. Use of ordered mesoporous silica to enhance the oral bioavailability of ezetimibe in dogs. J Pharm Sci 2012; 101: 1136-1144.
    • (2012) J Pharm Sci , vol.101 , pp. 1136-1144
    • Kiekens, F.1
  • 2
    • 84455200656 scopus 로고    scopus 로고
    • Application of mesoporous silicon dioxide and silicate in oral amorphous drug delivery systems
    • Qian K, Bogner R,. Application of mesoporous silicon dioxide and silicate in oral amorphous drug delivery systems. J Pharm Sci 2012; 101: 444-463.
    • (2012) J Pharm Sci , vol.101 , pp. 444-463
    • Qian, K.1    Bogner, R.2
  • 3
    • 84971201206 scopus 로고    scopus 로고
    • Evaluation of the dissolution behaviour of novel fenofibrate silica formulations in preprandial biorelevant media AAPS Poster M1189
    • Fei Y, et al. Evaluation of the dissolution behaviour of novel fenofibrate silica formulations in preprandial biorelevant media AAPS Poster M1189, AAPS Annual Meeting, San Antonio, Texas 2013.
    • (2013) AAPS Annual Meeting, San Antonio, Texas
    • Fei, Y.1
  • 4
    • 44749087279 scopus 로고    scopus 로고
    • Dissolution media simulating conditions in the proximal human gastrointestinal tract: An update
    • Jantratid E, et al. Dissolution media simulating conditions in the proximal human gastrointestinal tract: an update. Pharm Res 2008; 25: 1663-1676.
    • (2008) Pharm Res , vol.25 , pp. 1663-1676
    • Jantratid, E.1
  • 5
    • 82255162687 scopus 로고    scopus 로고
    • Supersaturating drug delivery systems: Fast is not necessarily good
    • Brewster M, Augustijns P,. Supersaturating drug delivery systems: fast is not necessarily good. J Pharm Sci 2012; 101: 7-9.
    • (2012) J Pharm Sci , vol.101 , pp. 7-9
    • Brewster, M.1    Augustijns, P.2
  • 6
    • 84866037370 scopus 로고    scopus 로고
    • Predicting the oral absorption of a poorly soluble, poorly permeable weak base using biorelevant dissolution and transfer models coupled with a physiologically based pharmacokinetic model
    • Wagner C, et al. Predicting the oral absorption of a poorly soluble, poorly permeable weak base using biorelevant dissolution and transfer models coupled with a physiologically based pharmacokinetic model. EJPB 2012; 82: 127-138.
    • (2012) EJPB , vol.82 , pp. 127-138
    • Wagner, C.1
  • 7
    • 80054989486 scopus 로고    scopus 로고
    • Precipitation in the small intestine may play a more important role in the absorption of poorly soluble weak bases: Case example nelfinavir
    • Shono Y, et al. Precipitation in the small intestine may play a more important role in the absorption of poorly soluble weak bases: case example nelfinavir. EJPB 2011; 79: 349-356.
    • (2011) EJPB , vol.79 , pp. 349-356
    • Shono, Y.1
  • 8
    • 1042269559 scopus 로고    scopus 로고
    • Predicting the precipitation of poorly soluble weak bases upon entry into the small intestine
    • Kostewicz E, et al. Predicting the precipitation of poorly soluble weak bases upon entry into the small intestine. J Pharm Pharmacol 2004; 56: 43-51.
    • (2004) J Pharm Pharmacol , vol.56 , pp. 43-51
    • Kostewicz, E.1
  • 9
    • 84912520944 scopus 로고    scopus 로고
    • Prediction of oral absorption of cinnarizine - A highly supersaturating poorly soluble weak base with borderline permeability
    • Berlin M, et al. Prediction of oral absorption of cinnarizine-a highly supersaturating poorly soluble weak base with borderline permeability. Eur J Pharm Biopharm 2014; 88: 795-806.
    • (2014) Eur J Pharm Biopharm , vol.88 , pp. 795-806
    • Berlin, M.1
  • 10
    • 33748210840 scopus 로고    scopus 로고
    • Synthesis based on the wet impregnation method and characterization of iron and iron oxide-silica nanocomposites
    • Alcalá M, Real M,. Synthesis based on the wet impregnation method and characterization of iron and iron oxide-silica nanocomposites. Solid State Ionics 2006; 177: 955-960.
    • (2006) Solid State Ionics , vol.177 , pp. 955-960
    • Alcalá, M.1    Real, M.2
  • 11
    • 79551516513 scopus 로고    scopus 로고
    • Biorelevant in vitro dissolution testing of micronized or nanosized products of fenofibrate with a view to predicting plasma profiles
    • Jünemann D, et al. Biorelevant in vitro dissolution testing of micronized or nanosized products of fenofibrate with a view to predicting plasma profiles. Eur J Pharm Biopharm 2011; 77: 257-264.
    • (2011) Eur J Pharm Biopharm , vol.77 , pp. 257-264
    • Jünemann, D.1
  • 12
    • 21544447265 scopus 로고    scopus 로고
    • Simulation of fasting gastric conditions and its importance for the in vivo dissolution of lipophilic compounds
    • Vertzoni M, et al. Simulation of fasting gastric conditions and its importance for the in vivo dissolution of lipophilic compounds. Eur J Pharm Biopharm 2005; 60: 413-417.
    • (2005) Eur J Pharm Biopharm , vol.60 , pp. 413-417
    • Vertzoni, M.1
  • 13
    • 84898803134 scopus 로고    scopus 로고
    • A simplified method to screen for in-vivo performance of oral lipid formulations
    • Kilic M, Dressman J,. A simplified method to screen for in-vivo performance of oral lipid formulations. J Pharm Pharmacol 2014; 66: 615-623.
    • (2014) J Pharm Pharmacol , vol.66 , pp. 615-623
    • Kilic, M.1    Dressman, J.2
  • 14
    • 84971221383 scopus 로고    scopus 로고
    • (accessed 18 February, 2015)
    • List of generally regarded as safe ingredients, US-HHS FDA. (accessed 18 February, 2015) http://www.accessdata.fda.gov/scripts/fdcc/index.cfm?set=SCOGS&sort=Sortsubstance&order=ASC&startrow=251&type=basic&search=.
    • List of Generally Regarded As Safe Ingredients, US-HHS FDA


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.