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Volumn 66, Issue 5, 2014, Pages 615-623

A simplified method to screen for in-vivo performance of oral lipid formulations

Author keywords

biorelevant media; drug precipitation; in vitro lipolysis; lipid formulations; poorly soluble drugs

Indexed keywords

CALCIUM; DANAZOL; DRUG CARRIER; LIPID; PANCREATIN;

EID: 84898803134     PISSN: 00223573     EISSN: 20427158     Source Type: Journal    
DOI: 10.1111/jphp.12182     Document Type: Article
Times cited : (18)

References (25)
  • 1
    • 34548049221 scopus 로고    scopus 로고
    • Oral lipid-based formulations
    • Hauss DJ,. Oral lipid-based formulations. Adv Drug Deliv Rev 2007; 59: 667-676.
    • (2007) Adv Drug Deliv Rev , vol.59 , pp. 667-676
    • Hauss, D.J.1
  • 2
    • 33751014029 scopus 로고    scopus 로고
    • Formulation of poorly water-soluble drugs for oral administration: Physicochemical and physiological issues and the lipid formulation classification system
    • Pouton CW,. Formulation of poorly water-soluble drugs for oral administration: physicochemical and physiological issues and the lipid formulation classification system. Eur J Pharm Sci 2006; 29: 278-287.
    • (2006) Eur J Pharm Sci , vol.29 , pp. 278-287
    • Pouton, C.W.1
  • 3
    • 39149092022 scopus 로고    scopus 로고
    • Enhancing intestinal drug solubilisation using lipid-based delivery systems
    • Porter CJ, et al. Enhancing intestinal drug solubilisation using lipid-based delivery systems. Adv Drug Deliv Rev 2008; 60: 673-691.
    • (2008) Adv Drug Deliv Rev , vol.60 , pp. 673-691
    • Porter, C.J.1
  • 4
    • 0033805858 scopus 로고    scopus 로고
    • Lipid formulations for oral administration of drugs: Non-emulsifying, self-emulsifying and 'self-microemulsifying' drug delivery systems
    • Pouton CW,. Lipid formulations for oral administration of drugs: non-emulsifying, self-emulsifying and 'self-microemulsifying' drug delivery systems. Eur J Pharm Sci 2000; 11: 93-98.
    • (2000) Eur J Pharm Sci , vol.11 , pp. 93-98
    • Pouton, C.W.1
  • 5
    • 33847394968 scopus 로고    scopus 로고
    • Lipids and lipid-based formulations: Optimizing the oral delivery of lipophilic drugs
    • Porter CJ, et al. Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs. Nat Rev Drug Discov 2007; 6: 231-248.
    • (2007) Nat Rev Drug Discov , vol.6 , pp. 231-248
    • Porter, C.J.1
  • 6
    • 0342617694 scopus 로고    scopus 로고
    • Lipid-based vehicles for the oral delivery of poorly water soluble drugs
    • Humberstone AJ, Charman WN,. Lipid-based vehicles for the oral delivery of poorly water soluble drugs. Adv Drug Deliv Rev 1997; 25: 103-128.
    • (1997) Adv Drug Deliv Rev , vol.25 , pp. 103-128
    • Humberstone, A.J.1    Charman, W.N.2
  • 7
    • 0343051926 scopus 로고    scopus 로고
    • Influence of lipolysis on drug absorption from the gastro-intestinal tract
    • MacGregor KJ, et al. Influence of lipolysis on drug absorption from the gastro-intestinal tract. Adv Drug Deliv Rev 1997; 25: 33-46.
    • (1997) Adv Drug Deliv Rev , vol.25 , pp. 33-46
    • MacGregor, K.J.1
  • 8
    • 33847364354 scopus 로고    scopus 로고
    • Increasing the proportional content of surfactant (Cremophor EL) relative to lipid in self-emulsifying lipid-based formulations of danazol reduces oral bioavailability in beagle dogs
    • Cuine JF, et al. Increasing the proportional content of surfactant (Cremophor EL) relative to lipid in self-emulsifying lipid-based formulations of danazol reduces oral bioavailability in beagle dogs. Pharm Res 2007; 24: 748-757.
    • (2007) Pharm Res , vol.24 , pp. 748-757
    • Cuine, J.F.1
  • 9
    • 39149091886 scopus 로고    scopus 로고
    • Evaluation of the impact of surfactant digestion on the bioavailability of danazol after oral administration of lipidic self-emulsifying formulations to dogs
    • Cuine JF, et al. Evaluation of the impact of surfactant digestion on the bioavailability of danazol after oral administration of lipidic self-emulsifying formulations to dogs. J Pharm Sci 2008; 97: 995-1012.
    • (2008) J Pharm Sci , vol.97 , pp. 995-1012
    • Cuine, J.F.1
  • 10
    • 0034898463 scopus 로고    scopus 로고
    • A dynamic in vitro lipolysis model. I. Controlling the rate of lipolysis by continuous addition of calcium
    • Zangenberg NH, et al. A dynamic in vitro lipolysis model. I. Controlling the rate of lipolysis by continuous addition of calcium. Eur J Pharm Sci 2001; 14: 115-122.
    • (2001) Eur J Pharm Sci , vol.14 , pp. 115-122
    • Zangenberg, N.H.1
  • 11
    • 0035016152 scopus 로고    scopus 로고
    • Characterisation and quantification of medium chain and long chain triglycerides and their in vitro digestion products, by HPTLC coupled with in situ densitometric analysis
    • Sek L, et al. Characterisation and quantification of medium chain and long chain triglycerides and their in vitro digestion products, by HPTLC coupled with in situ densitometric analysis. J Pharm Biomed Anal 2001; 25: 651-661.
    • (2001) J Pharm Biomed Anal , vol.25 , pp. 651-661
    • Sek, L.1
  • 12
    • 34247536339 scopus 로고    scopus 로고
    • Morphological observations on a lipid-based drug delivery system during in vitro digestion
    • Fatouros DG, et al. Morphological observations on a lipid-based drug delivery system during in vitro digestion. Eur J Pharm Sci 2007; 31: 85-94.
    • (2007) Eur J Pharm Sci , vol.31 , pp. 85-94
    • Fatouros, D.G.1
  • 13
    • 44749087279 scopus 로고    scopus 로고
    • Dissolution media simulating conditions in the proximal human gastrointestinal tract: An update
    • Jantratid E, et al. Dissolution media simulating conditions in the proximal human gastrointestinal tract: an update. Pharm Res 2008; 25: 1663-1676.
    • (2008) Pharm Res , vol.25 , pp. 1663-1676
    • Jantratid, E.1
  • 14
    • 12244263506 scopus 로고    scopus 로고
    • Comparison of a miniaturized shake-flask solubility method with automated potentiometric acid/base titrations and calculated solubilities
    • Glomme A, et al. Comparison of a miniaturized shake-flask solubility method with automated potentiometric acid/base titrations and calculated solubilities. J Pharm Sci 2005; 94: 1-16.
    • (2005) J Pharm Sci , vol.94 , pp. 1-16
    • Glomme, A.1
  • 16
    • 0030900392 scopus 로고    scopus 로고
    • Duodenal and ileal nutrient deliveries regulate human intestinal motor and pancreatic responses to a meal
    • Keller J, et al. Duodenal and ileal nutrient deliveries regulate human intestinal motor and pancreatic responses to a meal. Am J Physiol 1997; 272: 632-637.
    • (1997) Am J Physiol , vol.272 , pp. 632-637
    • Keller, J.1
  • 17
    • 20944443596 scopus 로고    scopus 로고
    • Human pancreatic exocrine response to nutrients in health and disease
    • Keller J, Layer P,. Human pancreatic exocrine response to nutrients in health and disease. Gut 2005; 54: 1-28.
    • (2005) Gut , vol.54 , pp. 1-28
    • Keller, J.1    Layer, P.2
  • 18
    • 0024264002 scopus 로고
    • Effect of atropine on intestinal phase of pancreatic secretion in man
    • Bozkurt T, et al. Effect of atropine on intestinal phase of pancreatic secretion in man. Digestion 1988; 41: 108-115.
    • (1988) Digestion , vol.41 , pp. 108-115
    • Bozkurt, T.1
  • 19
    • 0029737561 scopus 로고    scopus 로고
    • Physicochemical characteristics of emulsions during fat digestion in human stomach and duodenum
    • Armand M, et al. Physicochemical characteristics of emulsions during fat digestion in human stomach and duodenum. Am J Physiol 1996; 271: 172-183.
    • (1996) Am J Physiol , vol.271 , pp. 172-183
    • Armand, M.1
  • 20
    • 0030996647 scopus 로고    scopus 로고
    • Combined effect of a lecithin and a bile salt on pancreatic lipase activity
    • Lykidis A, et al. Combined effect of a lecithin and a bile salt on pancreatic lipase activity. Comp Biochem Physiol B Biochem Mol Biol 1997; 116: 51-55.
    • (1997) Comp Biochem Physiol B Biochem Mol Biol , vol.116 , pp. 51-55
    • Lykidis, A.1
  • 21
    • 33747049558 scopus 로고    scopus 로고
    • Characterization of fasted-state human intestinal fluids collected from duodenum and jejunum
    • Perez de la Cruz Moreno M, et al. Characterization of fasted-state human intestinal fluids collected from duodenum and jejunum. J Pharm Pharmacol 2006; 58: 1079-1089.
    • (2006) J Pharm Pharmacol , vol.58 , pp. 1079-1089
    • Perez De La Cruz Moreno, M.1
  • 22
    • 0002231361 scopus 로고
    • The light microscopy of triglyceride digestion
    • Patton JS, et al. The light microscopy of triglyceride digestion. Food Microstruct 1985; 4: 29-41.
    • (1985) Food Microstruct , vol.4 , pp. 29-41
    • Patton, J.S.1
  • 23
    • 62849112101 scopus 로고    scopus 로고
    • Postprandial evolution in composition and characteristics of human duodenal fluids in different nutritional states
    • Clarysse S, et al. Postprandial evolution in composition and characteristics of human duodenal fluids in different nutritional states. J Pharm Sci 2009; 98: 1177-1192.
    • (2009) J Pharm Sci , vol.98 , pp. 1177-1192
    • Clarysse, S.1
  • 24
    • 84860781171 scopus 로고    scopus 로고
    • Luminal lipid phases after administration of a triglyceride solution of danazol in the fed state and their contribution to the flux of danazol across Caco-2 cell monolayers
    • Vertzoni M, et al. Luminal lipid phases after administration of a triglyceride solution of danazol in the fed state and their contribution to the flux of danazol across Caco-2 cell monolayers. Mol Pharm 2012; 9: 1189-1198.
    • (2012) Mol Pharm , vol.9 , pp. 1189-1198
    • Vertzoni, M.1
  • 25
    • 27744515754 scopus 로고    scopus 로고
    • Intestinal fluid volumes and transit of dosage forms as assessed by magnetic resonance imaging
    • Schiller C, et al. Intestinal fluid volumes and transit of dosage forms as assessed by magnetic resonance imaging. Aliment Pharmacol Ther 2005; 22: 971-979.
    • (2005) Aliment Pharmacol Ther , vol.22 , pp. 971-979
    • Schiller, C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.