Use of ordered mesoporous silica to enhance the oral bioavailability of ezetimibe in dogs

Journal of Pharmaceutical Sciences

Volumn 101, Issue 3, 2012, Pages 1136-1144

  Kiekens, Filip ^a   Eelen, Siemon ^a   Verheyden, Loes ^a   Daems, Tinne ^a   Martens, Johan ^b   van den Mooter, Guy ^b  

^a Formac Pharmaceuticals   (Belgium)

^b UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Ezetimibe; In vivo; Oral bioavailability; Ordered mesoporous silica; Poor solubility

Indexed keywords

DODECYL SULFATE SODIUM; EZETIMIBE; GLUCURONIDE; NITROGEN; ORDERED MESOPOROUS SILICA; POLYSORBATE 80; SILICON DIOXIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DOG; DRUG ABSORPTION; DRUG ADSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CAPSULE; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM COMPARISON; DRUG METABOLISM; DRUG RELEASE; DRUG SOLUBILITY; DRUG STABILITY; HYDROPHILICITY; IN VITRO STUDY; IN VIVO STUDY; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PHYSICAL CHEMISTRY; POROSITY; SINGLE DRUG DOSE; STOMACH JUICE; TABLET FORMULATION; TIME TO MAXIMUM PLASMA CONCENTRATION;

EID: 84855874314     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.23016     Document Type: Article

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