-
2
-
-
4043131841
-
Radioligand-binding methods for membrane preparations and intact cells
-
Bylund DB, Deupree JD, Toews ML (2004) Radioligand-binding methods for membrane preparations and intact cells. Methods Mol Biol 259:1–28
-
(2004)
Methods Mol Biol
, vol.259
, pp. 1-28
-
-
Bylund, D.B.1
Deupree, J.D.2
Toews, M.L.3
-
3
-
-
78651175536
-
The uptake of atropine and related drugs by intestinal smooth muscle of the guinea-pig in relation to acetylcholine receptors
-
Paton WDM, Rang HP (1965) The uptake of atropine and related drugs by intestinal smooth muscle of the guinea-pig in relation to acetylcholine receptors. Proc R Soc Lond B Biol Sci 163:1–44
-
(1965)
Proc R Soc Lond B Biol Sci
, vol.163
, pp. 1-44
-
-
Paton, W.1
Rang, H.P.2
-
4
-
-
72149097863
-
Guide to Receptors and Channels (GRAC), 4th edition
-
Alexander SPH, Mathie A, Peters JA (2009) Guide to Receptors and Channels (GRAC), 4th edition. Br J Pharmacol 158(suppl):S1–S254
-
(2009)
Br J Pharmacol
, vol.158
, pp. SS1-S254
-
-
Alexander, S.1
Mathie, A.2
Peters, J.A.3
-
5
-
-
0029048987
-
On the importance of the “antagonist assumption” to how receptors express themselves
-
Kenakin T (1995) On the importance of the “antagonist assumption” to how receptors express themselves. Biochem Pharmacol 55:17–26
-
(1995)
Biochem Pharmacol
, vol.55
, pp. 17-26
-
-
Kenakin, T.1
-
6
-
-
77952354490
-
Seven transmembrane receptors as shape shifting proteins: The impact of allosteric modulation and functional selectivity on new drug discovery
-
Kenakin T, Miller LJ (2010) Seven transmembrane receptors as shape shifting proteins: the impact of allosteric modulation and functional selectivity on new drug discovery. Pharmacol Rev 62:265–304
-
(2010)
Pharmacol Rev
, vol.62
, pp. 265-304
-
-
Kenakin, T.1
Miller, L.J.2
-
7
-
-
24744443181
-
Quantifying receptor properties: The tissue segment binding method—a powerful tool for the pharmacome analysis of native receptors
-
Muramatsu I, Tanaka T, Suzuki F, Li Z, Hiraizumi-Hiraoka Y, Anisuzzaman ASM, Yamamoto H, Horinouchi T, Morishima S (2005) Quantifying receptor properties: the tissue segment binding method—a powerful tool for the pharmacome analysis of native receptors. J Pharmacol Sci 98:331–339
-
(2005)
J Pharmacol Sci
, vol.98
, pp. 331-339
-
-
Muramatsu, I.1
Tanaka, T.2
Suzuki, F.3
Li, Z.4
Hiraizumi-Hiraoka, Y.5
Anisuzzaman, A.6
Yamamoto, H.7
Horinouchi, T.8
Morishima, S.9
-
8
-
-
34447625738
-
Multiple GPCR conformations and signaling pathways: Implications for antagonist affi nity estimates
-
Baker JG, Hill SJ (2007) Multiple GPCR conformations and signaling pathways: implications for antagonist affi nity estimates. Trends Pharmacol Sci 28:374–381
-
(2007)
Trends Pharmacol Sci
, vol.28
, pp. 374-381
-
-
Baker, J.G.1
Hill, S.J.2
-
9
-
-
33846909764
-
Phenotypic pharmacology: The infl uence of cellular environment on G protein-coupled receptor antagonist and inverse agonist pharmacology
-
Nelson CP, Challiss RAJ (2007) “Phenotypic” pharmacology: the infl uence of cellular environment on G protein-coupled receptor antagonist and inverse agonist pharmacology. Biochem Pharmacol 73:737–751
-
(2007)
Biochem Pharmacol
, vol.73
, pp. 737-751
-
-
Nelson, C.P.1
Challiss, R.2
-
11
-
-
0019217066
-
Pharmacological specifi city of brain histamine H2-receptors differs in intact cells and cell-free preparations
-
Toung MDT, Garbarg M, Schwartz JC (1980) Pharmacological specifi city of brain histamine H2-receptors differs in intact cells and cell-free preparations. Nature 287:548–551
-
(1980)
Nature
, vol.287
, pp. 548-551
-
-
Toung, M.1
Garbarg, M.2
Schwartz, J.C.3
-
12
-
-
84857090716
-
Phenotype Pharmacology of lower urinary tract α 1 -adrenoceptors
-
Nishimune A, Yoshiki H, Uwada J, Anisuzzaman AS, Umada H, Muramatsu I (2012) Phenotype Pharmacology of lower urinary tract α 1 -adrenoceptors. Br J Pharmacol 165:1226–1234
-
(2012)
Br J Pharmacol
, vol.165
, pp. 1226-1234
-
-
Nishimune, A.1
Yoshiki, H.2
Uwada, J.3
Anisuzzaman, A.S.4
Umada, H.5
Muramatsu, I.6
-
13
-
-
84918822206
-
Pharmacologically distinct phenotypes of α 1B - adrenoceptors: Variation in binding and functional affi nities for antagonists
-
Yoshiki H, Uwada J, Anisuzzaman ASM, Umada H, Hayashi R, Kainoh M, Masuoka T, Nishio M, Muramatsu I (2014) Pharmacologically distinct phenotypes of α 1B - adrenoceptors: variation in binding and functional affi nities for antagonists. Br J Pharmacol 171:4890–4901
-
(2014)
Br J Pharmacol
, vol.171
, pp. 4890-4901
-
-
Yoshiki, H.1
Uwada, J.2
Anisuzzaman, A.3
Umada, H.4
Hayashi, R.5
Kainoh, M.6
Masuoka, T.7
Nishio, M.8
Muramatsu, I.9
-
14
-
-
80053163064
-
Infl uence of tissue integrity of pharmacological phenotypes of muscarinic acetylcholine receptors in the rat cerebral cortex
-
Anisuzzaman ASM, Nishimune A, Yoshiki H, Uwada J, Muramatsu I (2011) Infl uence of tissue integrity of pharmacological phenotypes of muscarinic acetylcholine receptors in the rat cerebral cortex. J Pharmacol Exp Ther 339: 186–193
-
(2011)
J Pharmacol Exp Ther
, vol.339
, pp. 186-193
-
-
Anisuzzaman, A.1
Nishimune, A.2
Yoshiki, H.3
Uwada, J.4
Muramatsu, I.5
-
15
-
-
0031843494
-
Characterization of an atypical muscarinic cholinoceptor mediating contraction of the guinea-pig isolated uterus
-
Boxall DK, Ford AP, Choppin A, Nahorski SR, Challis RA, Eglen RM (1998) Characterization of an atypical muscarinic cholinoceptor mediating contraction of the guinea-pig isolated uterus. Br J Pharmacol 124:1615–1622
-
(1998)
Br J Pharmacol
, vol.124
, pp. 1615-1622
-
-
Boxall, D.K.1
Ford, A.P.2
Choppin, A.3
Nahorski, S.R.4
Challis, R.A.5
Eglen, R.M.6
-
16
-
-
0031939148
-
Pharmacological characterization of muscarinic receptors in the uterus of oestrogen-primed and pregnant rats
-
Munns M, Pennefather JN (1998) Pharmacological characterization of muscarinic receptors in the uterus of oestrogen-primed and pregnant rats. Br J Pharmacol 123:1639–1644
-
(1998)
Br J Pharmacol
, vol.123
, pp. 1639-1644
-
-
Munns, M.1
Pennefather, J.N.2
-
17
-
-
80052348922
-
Intracellular distribution of functional M1-muscarinic acetylcholine receptors in N1E-115 neuroblastoma cells
-
Uwada J, Anisuzzaman AMS, Yoshiki H, Nishimune A, Muramatsu I (2011) Intracellular distribution of functional M1-muscarinic acetylcholine receptors in N1E-115 neuroblastoma cells. J Neurochem 118:958–967
-
(2011)
J Neurochem
, vol.118
, pp. 958-967
-
-
Uwada, J.1
Anisuzzaman, A.2
Yoshiki, H.3
Nishimune, A.4
Muramatsu, I.5
-
18
-
-
84880570656
-
Novel contribution of cell surface and intracellular M1-muscarinic acetylcholine receptors to synaptic plasticity in hippocampus
-
Anisuzzaman AMS, Uwada J, Masuoka T, Yoshiki H, Nishio M, Ikegaya Y, Takahashi N, Matsuki N, Fujibayashi Y, Yonekura Y, Momiyama T, Muramatsu I (2013) Novel contribution of cell surface and intracellular M1-muscarinic acetylcholine receptors to synaptic plasticity in hippocampus. J Neurochem 126:360–371
-
(2013)
J Neurochem
, vol.126
, pp. 360-371
-
-
Anisuzzaman, A.1
Uwada, J.2
Masuoka, T.3
Yoshiki, H.4
Nishio, M.5
Ikegaya, Y.6
Takahashi, N.7
Matsuki, N.8
Fujibayashi, Y.9
Yonekura, Y.10
Momiyama, T.11
Muramatsu, I.12
-
19
-
-
1542329722
-
Alpha-1 adrenoceptors: Evaluation of receptor subtype-binding kinetics in intact arterial tissues and comparison with membrane binding
-
Tanaka T, Zhang L, Suzuki F, Muramatsu I (2004) Alpha-1 adrenoceptors: evaluation of receptor subtype-binding kinetics in intact arterial tissues and comparison with membrane binding. Br J Pharmacol 141:468–476
-
(2004)
Br J Pharmacol
, vol.141
, pp. 468-476
-
-
Tanaka, T.1
Zhang, L.2
Suzuki, F.3
Muramatsu, I.4
-
20
-
-
0020375867
-
The biphasic response of muscarinic receptors in cultured heart cells to agonists. Effects on receptor number and affi nity in intact cells and homogenates
-
Galper JB, Dziekan LC, O’Hara DS, Smith TW (1982) The biphasic response of muscarinic receptors in cultured heart cells to agonists. Effects on receptor number and affi nity in intact cells and homogenates. J Biol Chem 257:10344–10356
-
(1982)
J Biol Chem
, vol.257
, pp. 10344-10356
-
-
Galper, J.B.1
Dziekan, L.C.2
O’Hara, D.S.3
Smith, T.W.4
-
21
-
-
0030064567
-
Intracellular traffi cking of the muscarinic acetylcholine receptor: Importance of subtype and cell type
-
Koenig JA, Edwardson JM (1996) Intracellular traffi cking of the muscarinic acetylcholine receptor: importance of subtype and cell type. Mol Pharmacol 49:351–359
-
(1996)
Mol Pharmacol
, vol.49
, pp. 351-359
-
-
Koenig, J.A.1
Edwardson, J.M.2
-
22
-
-
0034663763
-
Dynamic mediates caveolar sequestration of muscarinic cholinergic receptors and alteration in NO signaling
-
Dessy C, Kelly RA, Balligand JL, Feron O (2000) Dynamic mediates caveolar sequestration of muscarinic cholinergic receptors and alteration in NO signaling. EMBO J 19:4272–4280
-
(2000)
EMBO J
, vol.19
, pp. 4272-4280
-
-
Dessy, C.1
Kelly, R.A.2
Balligand, J.L.3
Feron, O.4
-
23
-
-
40549112321
-
Assessment of muscarinic receptor subtypes in human and rat lower urinary tract by tissue segment binding assay
-
Anisuzzaman ASM, Morishima S, Suzuki F, Tanaka T, Yoshiki H, Sathi ZS, Akino H, Yokoyama O, Muramatsu I (2008) Assessment of muscarinic receptor subtypes in human and rat lower urinary tract by tissue segment binding assay. J Pharmacol Sci 106:271–279
-
(2008)
J Pharmacol Sci
, vol.106
, pp. 271-279
-
-
Anisuzzaman, A.1
Morishima, S.2
Suzuki, F.3
Tanaka, T.4
Yoshiki, H.5
Sathi, Z.S.6
Akino, H.7
Yokoyama, O.8
Muramatsu, I.9
-
24
-
-
84904285226
-
Intracellular localization of M1 muscarinic acetylcholine receptor through clathrin-dependent constitutive internalization via a C-terminal tryptophan-based motif
-
Uwada J, Yoshiki H, Masuoka T, Nishio M, Muramatsu I (2014) Intracellular localization of M1 muscarinic acetylcholine receptor through clathrin-dependent constitutive internalization via a C-terminal tryptophan-based motif. J Cell Sci 127:3131–3140
-
(2014)
J Cell Sci
, vol.127
, pp. 3131-3140
-
-
Uwada, J.1
Yoshiki, H.2
Masuoka, T.3
Nishio, M.4
Muramatsu, I.5
-
25
-
-
0037406701
-
Regulation of muscarinic acetylcholine receptor signaling
-
Van Koppen CJ, Kaiser B (2003) Regulation of muscarinic acetylcholine receptor signaling. Pharmacol Ther 98:197–220
-
(2003)
Pharmacol Ther
, vol.98
, pp. 197-220
-
-
Van Koppen, C.J.1
Kaiser, B.2
-
26
-
-
84954358440
-
Identifi cation of M1 muscarinic receptor subtype in rat stomach using a tissue segment binding method, and the effects of immobilization stress on the muscarinic receptors
-
Anisuzzaman ASM, Morishima S, Suzuki F, Tanaka T, Muramatsu I (2008) Identifi cation of M1 muscarinic receptor subtype in rat stomach using a tissue segment binding method, and the effects of immobilization stress on the muscarinic receptors. Eur J Pharmacol 599:146–151
-
(2008)
Eur J Pharmacol
, vol.599
, pp. 146-151
-
-
Anisuzzaman, A.1
Morishima, S.2
Suzuki, F.3
Tanaka, T.4
Muramatsu, I.5
-
27
-
-
84863197414
-
Regional quantifi cation of muscarinic acetylcholine receptors and β-adrenoceptors in human airway
-
Ikeda T, Anisuzzaman AMS, Yoshiki H, Sasaki M, Koshiji T, Nishimune A, Muramatsu I (2012) Regional quantifi cation of muscarinic acetylcholine receptors and β-adrenoceptors in human airway. Br J Pharmacol 166:1804–1814
-
(2012)
Br J Pharmacol
, vol.166
, pp. 1804-1814
-
-
Ikeda, T.1
Anisuzzaman, A.2
Yoshiki, H.3
Sasaki, M.4
Koshiji, T.5
Nishimune, A.6
Muramatsu, I.7
-
28
-
-
84884356794
-
M1 is a major subtype of muscarinic acetylcholine receptors on mouse epithelial cells
-
Khan RIM, Anisuzzaman AMS, Semba S, Ma Y, Uwada J et al (2013) M1 is a major subtype of muscarinic acetylcholine receptors on mouse epithelial cells. J Gastroenterol 48:885–896
-
(2013)
J Gastroenterol
, vol.48
, pp. 885-896
-
-
Khan, R.1
Anisuzzaman, A.2
Semba, S.3
Ma, Y.4
Uwada, J.5
-
29
-
-
84863192608
-
Re-evaluation of nicotinic acetylcholine receptors in rat brain by a tissuesegment binding assay
-
Wang MH, Yoshiki H, Anisuzzaman ASM, Uwada J, Nishimune A, Lee KS, Taniguchi T, Muramatsu I (2011) Re-evaluation of nicotinic acetylcholine receptors in rat brain by a tissuesegment binding assay. Front Pharmacol 2:65. doi: 10.3389/fphar.2011.00065
-
(2011)
Front Pharmacol
, vol.2
, pp. 65
-
-
Wang, M.H.1
Yoshiki, H.2
Anisuzzaman, A.3
Uwada, J.4
Nishimune, A.5
Lee, K.S.6
Taniguchi, T.7
Muramatsu, I.8
-
30
-
-
0019378908
-
Regulation of the postsynaptic alphaadrenergic receptor in rat mesenteric artery. Effects of chemical sympathectomy and epinephrine treatment
-
Colucci WS, Gimbrone JRMA, Alexander RW (1981) Regulation of the postsynaptic alphaadrenergic receptor in rat mesenteric artery. Effects of chemical sympathectomy and epinephrine treatment. Circ Res 48:104–111
-
(1981)
Circ Res
, vol.48
, pp. 104-111
-
-
Colucci, W.S.1
Gimbrone, J.2
Alexander, R.W.3
-
31
-
-
0034912630
-
Expression of a-adrenoceptor subtypes by smooth muscle cell and adventitial fi broblast in rat aorta and in cell culture
-
Faber JE, Yang N, Xin XH (2001) Expression of a-adrenoceptor subtypes by smooth muscle cell and adventitial fi broblast in rat aorta and in cell culture. J Pharmacol Exp Ther 298:441–452
-
(2001)
J Pharmacol Exp Ther
, vol.298
, pp. 441-452
-
-
Faber, J.E.1
Yang, N.2
Xin, X.H.3
-
32
-
-
4243084362
-
Identifi cation of alpha-1L adrenoceptor in rabbit ear artery
-
Hiraizumi-Hiraoka Y, Tanaka T, Yamamoto H, Suzuki F, Muramatsu I (2004) Identifi cation of alpha-1L adrenoceptor in rabbit ear artery. J Pharmacol Exp Ther 310:995–1002
-
(2004)
J Pharmacol Exp Ther
, vol.310
, pp. 995-1002
-
-
Hiraizumi-Hiraoka, Y.1
Tanaka, T.2
Yamamoto, H.3
Suzuki, F.4
Muramatsu, I.5
-
33
-
-
33745957756
-
Pharmacological evaluation of plasma membrane β-adrenoceptors in rat hearts using the tissue segment binding method
-
Horinouchi T, Morishima S, Tanaka T, Suzuki F, Tanaka Y, Kioke K, Muramatsu I (2006) Pharmacological evaluation of plasma membrane β-adrenoceptors in rat hearts using the tissue segment binding method. Life Sci 79: 941–948
-
(2006)
Life Sci
, vol.79
, pp. 941-948
-
-
Horinouchi, T.1
Morishima, S.2
Tanaka, T.3
Suzuki, F.4
Tanaka, Y.5
Kioke, K.6
Muramatsu, I.7
-
34
-
-
0024489928
-
Affi nity of muscarinic receptor antagonists for three putative muscarinic receptor binding sites
-
Delmendo RE, Michel AD, Whiting RL (1989) Affi nity of muscarinic receptor antagonists for three putative muscarinic receptor binding sites. Br J Pharmacol 96:457–464
-
(1989)
Br J Pharmacol
, vol.96
, pp. 457-464
-
-
Delmendo, R.E.1
Michel, A.D.2
Whiting, R.L.3
-
35
-
-
0025632856
-
Regional distribution of M1, M2 and non-M1, non-M2 subtypes of muscarinic binding sites in rat brain
-
Ehlert FJ, Tran LP (1990) Regional distribution of M1, M2 and non-M1, non-M2 subtypes of muscarinic binding sites in rat brain. J Pharmacol Exp Ther 255:1148–1157
-
(1990)
J Pharmacol Exp Ther
, vol.255
, pp. 1148-1157
-
-
Ehlert, F.J.1
Tran, L.P.2
-
36
-
-
41349102130
-
Different affi nities of native α1Badrenoceptors for ketanserin between intact tissue segments and membrane preparation
-
Sathi ZS, Anisuzzaman ASM, Morishima S, Suzuki F, Tanaka T, Yoshiki H, Muramatsu I (2008) Different affi nities of native α1Badrenoceptors for ketanserin between intact tissue segments and membrane preparation. Eur J Pharmacol 584:22–228
-
(2008)
Eur J Pharmacol
, vol.584
, pp. 22-228
-
-
Sathi, Z.S.1
Anisuzzaman, A.2
Morishima, S.3
Suzuki, F.4
Tanaka, T.5
Yoshiki, H.6
Muramatsu, I.7
|