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Volumn 19, Issue 16, 2000, Pages 4272-4280

Dynamin mediates caveolar sequestration of muscarinic cholinergic receptors and alteration in NO signaling

Author keywords

Caveolae; Caveolin; Dynamin; ENOS; mAchR

Indexed keywords

CARBACHOL; CHOLINERGIC RECEPTOR; DYNAMIN; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); MUSCARINIC RECEPTOR; NITRIC OXIDE SYNTHASE; RADIOLIGAND;

EID: 0034663763     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/19.16.4272     Document Type: Article
Times cited : (93)

References (29)
  • 1
    • 0031692336 scopus 로고    scopus 로고
    • The caveolae membrane system
    • Anderson, R.G.W. (1998) The caveolae membrane system. Annu. Rev. Biochem., 67, 199-225.
    • (1998) Annu. Rev. Biochem. , vol.67 , pp. 199-225
    • Anderson, R.G.W.1
  • 2
    • 0026545612 scopus 로고
    • Potocytosis: Sequestration and transport of small molecules by caveolae
    • Anderson, R.G., Kamen, B.A., Rothberg, K.G. and Lacey, S.W. (1992) Potocytosis: sequestration and transport of small molecules by caveolae. Science, 255, 410-411.
    • (1992) Science , vol.255 , pp. 410-411
    • Anderson, R.G.1    Kamen, B.A.2    Rothberg, K.G.3    Lacey, S.W.4
  • 3
  • 4
    • 0030895486 scopus 로고    scopus 로고
    • Regulation by cAMP on post-translational processing and subcellular targeting of endothelial nitric oxide synthase (type 3) in cardiac myocytes
    • Belhassen, L., Feron, O., Kaye, D.M., Michel, T., Smith, T.W. and Kelly, R.A. (1997) Regulation by cAMP on post-translational processing and subcellular targeting of endothelial nitric oxide synthase (type 3) in cardiac myocytes. J. Biol. Chem., 272, 11198-11204.
    • (1997) J. Biol. Chem. , vol.272 , pp. 11198-11204
    • Belhassen, L.1    Feron, O.2    Kaye, D.M.3    Michel, T.4    Smith, T.W.5    Kelly, R.A.6
  • 5
    • 0023191072 scopus 로고
    • Identification of a family of muscarinic acetylcholine receptor genes
    • Bonner, T.I., Buckley, N.J., Young, A.C. and Brann, M.R. (1987) Identification of a family of muscarinic acetylcholine receptor genes. Science, 237, 527-532.
    • (1987) Science , vol.237 , pp. 527-532
    • Bonner, T.I.1    Buckley, N.J.2    Young, A.C.3    Brann, M.R.4
  • 6
    • 0033605584 scopus 로고    scopus 로고
    • Regulation of G protein-coupled receptor kinases by caveolin
    • Carman, C.V., Lisanti, M.P. and Benovic, J.L. (1999) Regulation of G protein-coupled receptor kinases by caveolin. J. Biol. Chem., 274, 8858-8864.
    • (1999) J. Biol. Chem. , vol.274 , pp. 8858-8864
    • Carman, C.V.1    Lisanti, M.P.2    Benovic, J.L.3
  • 7
    • 0029787241 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase targeting to caveolae: Specific interactions with caveolin isoforms in cardiac myocytes and endothelial cells
    • Feron, O., Belhassen, L., Kobzik, L., Smith, T.W., Kelly, R.A. and Michel, T. (1996) Endothelial nitric oxide synthase targeting to caveolae: specific interactions with caveolin isoforms in cardiac myocytes and endothelial cells. J. Biol. Chem., 271, 22810-22814.
    • (1996) J. Biol. Chem. , vol.271 , pp. 22810-22814
    • Feron, O.1    Belhassen, L.2    Kobzik, L.3    Smith, T.W.4    Kelly, R.A.5    Michel, T.6
  • 8
    • 0030873019 scopus 로고    scopus 로고
    • Dynamic targeting of agonist-stimulated muscarinic cholinergic receptor to caveolae in cardiac myocytes
    • Feron, O., Smith, T.W., Michel, T. and Kelly, R.A. (1997a) Dynamic targeting of agonist-stimulated muscarinic cholinergic receptor to caveolae in cardiac myocytes. J. Biol. Chem., 272, 17744-17748.
    • (1997) J. Biol. Chem. , vol.272 , pp. 17744-17748
    • Feron, O.1    Smith, T.W.2    Michel, T.3    Kelly, R.A.4
  • 9
    • 0342575825 scopus 로고    scopus 로고
    • Caveolar targeting and regulation of the muscarinic cholinergic receptor/eNOS pathway in cardiac myocytes and in a heterologous expression system
    • Feron, O., Michel, T. and Kelly, R.A. (1997b) Caveolar targeting and regulation of the muscarinic cholinergic receptor/eNOS pathway in cardiac myocytes and in a heterologous expression system. Circulation, 96, 1-297.
    • (1997) Circulation , vol.96 , pp. 1-297
    • Feron, O.1    Michel, T.2    Kelly, R.A.3
  • 10
    • 0032488594 scopus 로고    scopus 로고
    • Dynamic regulation of eNOS: Complementary roles of dual acylation and caveolin interactions
    • Feron, O., Michel, JB., Kazu, S. and Michel, T. (1998a) Dynamic regulation of eNOS: complementary roles of dual acylation and caveolin interactions. Biochemistry, 37, 193-200.
    • (1998) Biochemistry , vol.37 , pp. 193-200
    • Feron, O.1    Michel, J.B.2    Kazu, S.3    Michel, T.4
  • 11
    • 0032515154 scopus 로고    scopus 로고
    • Modulation of the eNOS-caveolin interactions in cardiac myocytes: Implications for the autonomic regulation of heart rate
    • Feron, O., Dessy, C., Opel, D.J., Arstall, M.A., Kelly, R.A. and Michel, T. (1998b) Modulation of the eNOS-caveolin interactions in cardiac myocytes: implications for the autonomic regulation of heart rate. J. Biol. Chem., 273, 30249-30254.
    • (1998) J. Biol. Chem. , vol.273 , pp. 30249-30254
    • Feron, O.1    Dessy, C.2    Opel, D.J.3    Arstall, M.A.4    Kelly, R.A.5    Michel, T.6
  • 13
    • 0033559692 scopus 로고    scopus 로고
    • High LDL cholesterol decreases endothelial cell production of nitric oxide by promoting caveolin/eNOS inhibitory interaction
    • Feron, O., Dessy, C., Moniotte, S., Desager, J.-P. and Balligand, J.-L. (1999) High LDL cholesterol decreases endothelial cell production of nitric oxide by promoting caveolin/eNOS inhibitory interaction. J. Clin. Invest., 103, 897-905.
    • (1999) J. Clin. Invest. , vol.103 , pp. 897-905
    • Feron, O.1    Dessy, C.2    Moniotte, S.3    Desager, J.-P.4    Balligand, J.-L.5
  • 14
    • 0039397709 scopus 로고    scopus 로고
    • Dissecting the interaction between nitric oxide synthase (NOS) and caveolin. Functional significance of the NOS/caveolin binding domain in vivo
    • Garcia-Cardena, G., Martasek, P., Masters, B.S.S., Skidd, P.M., Couet, J., Li, S., Lisanti, M.P. and Sessa, W.C. (1997) Dissecting the interaction between nitric oxide synthase (NOS) and caveolin. Functional significance of the NOS/caveolin binding domain in vivo. J. Biol. Chem., 272, 25437-25440.
    • (1997) J. Biol. Chem. , vol.272 , pp. 25437-25440
    • Garcia-Cardena, G.1    Martasek, P.2    Masters, B.S.S.3    Skidd, P.M.4    Couet, J.5    Li, S.6    Lisanti, M.P.7    Sessa, W.C.8
  • 16
    • 0032557450 scopus 로고    scopus 로고
    • Arrestin-independent internalization of the m1, m3, and m4 subtypes of muscarinic cholinergic receptors
    • Lee, K.B., Pals-Rylaarsdam, R., Benovic, J.L. and Hosey, M.M. (1998) Arrestin-independent internalization of the m1, m3, and m4 subtypes of muscarinic cholinergic receptors. J. Biol. Chem., 273, 12967-12972.
    • (1998) J. Biol. Chem. , vol.273 , pp. 12967-12972
    • Lee, K.B.1    Pals-Rylaarsdam, R.2    Benovic, J.L.3    Hosey, M.M.4
  • 17
    • 0032563291 scopus 로고    scopus 로고
    • G protein-coupled receptors. III. New roles for receptor kinases and β-arrestins in receptor signaling and desensitization
    • Lefkowitz, R.J. (1998) G protein-coupled receptors. III. New roles for receptor kinases and β-arrestins in receptor signaling and desensitization. J. Biol. Chem., 273, 18677-18680.
    • (1998) J. Biol. Chem. , vol.273 , pp. 18677-18680
    • Lefkowitz, R.J.1
  • 18
    • 0032489880 scopus 로고    scopus 로고
    • Dynamin at the neck of caveolae mediates their budding to form transport vesicles by GTP-driven fission from the plasma membrane of endothelium
    • Oh, P., McIntosh, D.P. and Schnitzer, J.E. (1998) Dynamin at the neck of caveolae mediates their budding to form transport vesicles by GTP-driven fission from the plasma membrane of endothelium. J. Cell Biol., 141, 101-114.
    • (1998) J. Cell Biol. , vol.141 , pp. 101-114
    • Oh, P.1    McIntosh, D.P.2    Schnitzer, J.E.3
  • 19
    • 0032489443 scopus 로고    scopus 로고
    • Caveolins, a family of scaffolding proteins for organizing 'preassembled signaling complexes' at the plasma membrane
    • Okamoto, T., Schlegel, A., Scherer, P.E. and Lisanti, M.P. (1998) Caveolins, a family of scaffolding proteins for organizing 'preassembled signaling complexes' at the plasma membrane. J. Biol. Chem., 273, 5419-5422.
    • (1998) J. Biol. Chem. , vol.273 , pp. 5419-5422
    • Okamoto, T.1    Schlegel, A.2    Scherer, P.E.3    Lisanti, M.P.4
  • 20
    • 0031750101 scopus 로고    scopus 로고
    • Filipin-dependent inhibition of cholera toxin: Evidence for toxin internalization and activation through caveolae-like domains
    • Orlandi, P.A. and Fishman, P.H. (1998) Filipin-dependent inhibition of cholera toxin: evidence for toxin internalization and activation through caveolae-like domains. J. Cell Biol., 141, 905-915.
    • (1998) J. Cell Biol. , vol.141 , pp. 905-915
    • Orlandi, P.A.1    Fishman, P.H.2
  • 21
    • 0028829471 scopus 로고
    • Desensitization and internalization of the m2 muscarinic acetylcholine receptor are directed by independent mechanisms
    • Pals-Rylaarsdam, R., Xu, Y., Witt-Enderby, P., Benovic, J.L. and Hosey, M.M. (1995) Desensitization and internalization of the m2 muscarinic acetylcholine receptor are directed by independent mechanisms. J. Biol. Chem., 270, 29004-29011.
    • (1995) J. Biol. Chem. , vol.270 , pp. 29004-29011
    • Pals-Rylaarsdam, R.1    Xu, Y.2    Witt-Enderby, P.3    Benovic, J.L.4    Hosey, M.M.5
  • 22
    • 0030863054 scopus 로고    scopus 로고
    • Internalization of the m2 muscarinic acetylcholine receptor. Arrestin-independent and -dependent pathways
    • Pals-Rylaarsdam, R., Gurevich, V.V., Lee, K.B., Ptasienski, J.A., Benovic, J.L. and Hosey, M.M. (1997) Internalization of the m2 muscarinic acetylcholine receptor. Arrestin-independent and -dependent pathways. J. Biol. Chem., 272, 23682-23689.
    • (1997) J. Biol. Chem. , vol.272 , pp. 23682-23689
    • Pals-Rylaarsdam, R.1    Gurevich, V.V.2    Lee, K.B.3    Ptasienski, J.A.4    Benovic, J.L.5    Hosey, M.M.6
  • 23
    • 0029003932 scopus 로고
    • Caveolin isoforms differ in their N-terminal protein sequence and subcellular distribution. Identification and epitope mapping of an isoform-specific monoclonal antibody probe
    • Scherer, P.E., Tang, Z., Chun, M., Sargiacomo, M., Lodish, H.F. and Lisanti, M.P. (1995) Caveolin isoforms differ in their N-terminal protein sequence and subcellular distribution. Identification and epitope mapping of an isoform-specific monoclonal antibody probe. J. Biol. Chem., 270, 16395-16401.
    • (1995) J. Biol. Chem. , vol.270 , pp. 16395-16401
    • Scherer, P.E.1    Tang, Z.2    Chun, M.3    Sargiacomo, M.4    Lodish, H.F.5    Lisanti, M.P.6
  • 24
    • 0030872410 scopus 로고    scopus 로고
    • Synergistic regulation of m2 muscarinic acetylcholine receptor desensitization and sequestration by G protein-coupled receptor kinase-2 and β-arrestin-1
    • Schlador, M.L. and Nathanson, N.M. (1997) Synergistic regulation of m2 muscarinic acetylcholine receptor desensitization and sequestration by G protein-coupled receptor kinase-2 and β-arrestin-1. J. Biol. Chem., 272, 18882-18890.
    • (1997) J. Biol. Chem. , vol.272 , pp. 18882-18890
    • Schlador, M.L.1    Nathanson, N.M.2
  • 25
    • 0029809310 scopus 로고    scopus 로고
    • Role of GTP hydrolysis in fission of caveolae directly from plasma membranes
    • Schnitzer, J.E., Oh, P. and McIntosh, D.P. (1996) Role of GTP hydrolysis in fission of caveolae directly from plasma membranes. Science, 274, 239-242.
    • (1996) Science , vol.274 , pp. 239-242
    • Schnitzer, J.E.1    Oh, P.2    McIntosh, D.P.3
  • 26
    • 0028125208 scopus 로고
    • Caveolin moves from caveolae to the Golgi apparatus in response to cholesterol oxidation
    • Smart, E.J., Ying, Y.S., Conrad, P.A. and Anderson, R.G. (1994) Caveolin moves from caveolae to the Golgi apparatus in response to cholesterol oxidation. J. Cell Biol., 127, 1185-1197.
    • (1994) J. Cell Biol. , vol.127 , pp. 1185-1197
    • Smart, E.J.1    Ying, Y.S.2    Conrad, P.A.3    Anderson, R.G.4
  • 27
    • 0028568644 scopus 로고
    • Sequestration of muscarinic acetylcholine receptor m2 subtypes. Facilitation by G protein-coupled receptor kinase (GRK2) and attenuation by a dominant-negative mutant of GRK2
    • Tsuga, H., Kameyama, K., Haga, T., Kurose, H. and Nagao, T. (1994) Sequestration of muscarinic acetylcholine receptor m2 subtypes. Facilitation by G protein-coupled receptor kinase (GRK2) and attenuation by a dominant-negative mutant of GRK2. J. Biol. Chem., 269, 32522-32527.
    • (1994) J. Biol. Chem. , vol.269 , pp. 32522-32527
    • Tsuga, H.1    Kameyama, K.2    Haga, T.3    Kurose, H.4    Nagao, T.5
  • 28
    • 0032524334 scopus 로고    scopus 로고
    • Receptor subtype-specific regulation of muscarinic acetylcholine receptor sequestration by dynamin. Distinct sequestration of m2 receptors
    • Vögler, O., Bogatkewitsch, S., Wriske, C., Krummenerl, P., Jakobs, K.H. and van Koppen, C.J. (1998) Receptor subtype-specific regulation of muscarinic acetylcholine receptor sequestration by dynamin. Distinct sequestration of m2 receptors. J. Biol. Chem., 273, 12155-12160.
    • (1998) J. Biol. Chem. , vol.273 , pp. 12155-12160
    • Vögler, O.1    Bogatkewitsch, S.2    Wriske, C.3    Krummenerl, P.4    Jakobs, K.H.5    Van Koppen, C.J.6
  • 29
    • 0040017536 scopus 로고    scopus 로고
    • Regulation of muscarinic acetylcholine receptor sequestration and function by β-arrestin
    • Vögler, O., Nolte, B., Voss, M., Scmidt, M., Jakobs, K.H. and van Koppen, C.J. (1999) Regulation of muscarinic acetylcholine receptor sequestration and function by β-arrestin. J. Biol. Chem., 274, 12333-12338.
    • (1999) J. Biol. Chem. , vol.274 , pp. 12333-12338
    • Vögler, O.1    Nolte, B.2    Voss, M.3    Scmidt, M.4    Jakobs, K.H.5    Van Koppen, C.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.