Divergent Urinary Metabolic Phenotypes between Major Depressive Disorder and Bipolar Disorder Identified by a Combined GC-MS and NMR Spectroscopic Metabonomic Approach

Journal of Proteome Research

Volumn 14, Issue 8, 2015, Pages 3382-3389

  Chen, Jian Jun ^a   Zhou, Chan Juan ^a   Liu, Zhao ^a,b   Fu, Yu Ying ^a,b   Zheng, Peng ^a,b   Yang, De Yu ^a   Li, Qi ^a,b   Mu, Jun ^a,b   Wei, You Dong ^a,b   Zhou, Jing Jing ^a,b   Huang, Hua ^a,b   Xie, Peng ^a,b  

^a CHONGQING MEDICAL UNIVERSITY   (China)

^b THE FIRST AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

BD; biomarker; bipolar disorder; gas chromatography mass spectrometry; GC MS; major depressive disorder; MDD; metabonomic; NMR; nuclear magnetic resonance

Indexed keywords

2,3 DIHYDROXYBUTANOIC ACID; 3 AMINO 2 METHYLPROPIONIC ACID; 4 HYDROXYBENZOIC ACID; 5 HYDROXYHEXANOIC ACID; ACETONE; ADIPIC ACID; ALPHA HYDROXYBUTYRIC ACID; ARABINITOL; AZELAIC ACID; BETA ALANINE; BIOLOGICAL MARKER; BUTYRIC ACID DERIVATIVE; FORMIC ACID; GLYCINE; GLYCOLIC ACID; HEXANOIC ACID DERIVATIVE; HYDROXYBUTYRIC ACID; LACTIC ACID; MANNITOL; METHYLMALONIC ACID; PHENYLALANINE; PROPIONIC ACID; PYROGLUTAMIC ACID; UNCLASSIFIED DRUG; URACIL; 2,4-DIHYDROXYPYRIMIDINE; 3,4-DIHYDROXYBUTANOIC ACID; FORMIC ACID DERIVATIVE; PROPIONIC ACID DERIVATIVE; PYRIMIDINE DERIVATIVE;

ADULT; ARTICLE; BIPOLAR DISORDER; BIPOLAR I DISORDER; BIPOLAR II DISORDER; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; DIVERGENT URINARY METABOLIC PHENOTYPE; FEMALE; GAS CHROMATOGRAPH; HUMAN; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; MASS FRAGMENTOGRAPHY; MASS SPECTROMETER; METABOLIC PARAMETERS; METABOLOMICS; METABONOMICS; NUCLEAR MAGNETIC RESONANCE SPECTROMETER; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHENOTYPE; PRIORITY JOURNAL; RECEIVER OPERATING CHARACTERISTIC; SENSITIVITY AND SPECIFICITY; UROGENITAL SYSTEM PARAMETERS; DEPRESSIVE DISORDER, MAJOR; DIFFERENTIAL DIAGNOSIS; METABOLISM; METABOLOME; PROCEDURES; REPRODUCIBILITY; URINE; YOUNG ADULT;

ADULT; BETA-ALANINE; BIOMARKERS; BIPOLAR DISORDER; DEPRESSIVE DISORDER, MAJOR; DIAGNOSIS, DIFFERENTIAL; FEMALE; FORMATES; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; HYDROXYBUTYRATES; MAGNETIC RESONANCE SPECTROSCOPY; MALE; METABOLOME; METABOLOMICS; PHENYLALANINE; PROPIONATES; PYRIMIDINES; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; YOUNG ADULT;

EID: 84938809162     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/acs.jproteome.5b00434     Document Type: Article

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