A Novel Antiviral Target Structure Involved in the RNA Binding, Dimerization, and Nuclear Export Functions of the Influenza A Virus Nucleoprotein

PLoS Pathogens

Volumn 11, Issue 7, 2015, Pages

  Kakisaka, Michinori ^a   Sasaki, Yutaka ^a   Yamada, Kazunori ^a,b   Kondoh, Yasumitsu ^c   Hikono, Hirokazu ^d   Osada, Hiroyuki ^c   Tomii, Kentaro ^b   Saito, Takehiko ^d   Aida, Yoko ^a  

^a RIKEN   (Japan)

^b NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^c RIKEN Center for Sustainable Resource Science   (Japan)

^d NATIONAL INSTITUTE OF ANIMAL HEALTH   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; OSELTAMIVIR; RIBONUCLEOPROTEIN; RK424; UNCLASSIFIED DRUG; VIRUS NUCLEOPROTEIN; CORE PROTEIN; NP PROTEIN, INFLUENZA A VIRUS; RNA BINDING PROTEIN; VIRUS RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIVIRAL ACTIVITY; ANTIVIRAL THERAPY; ARTICLE; AVIAN INFLUENZA VIRUS; COMPUTER MODEL; CONTROLLED STUDY; CYTOTOXICITY ASSAY; DIMERIZATION; DRUG BINDING; FLUORESCENCE IN SITU HYBRIDIZATION; GEL PERMEATION CHROMATOGRAPHY; GENETIC ANALYSIS; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; MOLECULAR DOCKING; NONHUMAN; NUCLEAR EXPORT SIGNAL; OLIGOMERIZATION; PLAQUE ASSAY; PLASMID; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN TARGETING; RNA BINDING; SEQUENCE ANALYSIS; STRUCTURE ACTIVITY RELATION; SURFACE PLASMON RESONANCE; SYNTHESIS; VIRUS RECOMBINANT; VIRUS REPLICATION; WESTERN BLOTTING; ACTIVE TRANSPORT; ANIMAL; DRUG EFFECTS; INFLUENZA A VIRUS; METABOLISM; MOUSE; PROTEIN MULTIMERIZATION;

AVES; INFLUENZA A VIRUS; MUS; ORTHOMYXOVIRIDAE; SWINE INFLUENZA VIRUS;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; ANTIVIRAL AGENTS; HUMANS; INFLUENZA A VIRUS; MICE; PROTEIN MULTIMERIZATION; RNA, VIRAL; RNA-BINDING PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; VIRAL CORE PROTEINS;

EID: 84938795420     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1005062     Document Type: Article

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