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Volumn 10, Issue 11, 2012, Pages 793-801

Dimethyl fumarate - Only an anti-psoriatic medication?;Dimethylfumarat "nur" ein Anti-Psoriatikum?

Author keywords

angiogenesis; dimethyl fumarate; multiple sclerosis; necrobiosis lipoidica; psoriasis; tumor

Indexed keywords

DERMATOLOGICAL AGENT; FUMARIC ACID DERIVATIVE; FUMARIC ACID DIMETHYL ESTER; IMMUNOSUPPRESSIVE AGENT;

EID: 84868329304     PISSN: 16100379     EISSN: 16100387     Source Type: Journal    
DOI: 10.1111/j.1610-0387.2012.07996.x     Document Type: Review
Times cited : (83)

References (66)
  • 1
    • 70449253356 scopus 로고
    • Behandlung der Psoriasis vulgaris
    • Schweckendiek W,. Behandlung der Psoriasis vulgaris. Med Monatsschr 1959; 13: 103-4.
    • (1959) Med Monatsschr , vol.13 , pp. 103-104
    • Schweckendiek, W.1
  • 3
    • 58149355788 scopus 로고    scopus 로고
    • Detection of metabolites of fumaric acid esters in human urine: Implications for their mode of action
    • Rostami-Yazdi M, Clement B, Schmidt TJ, Schinor D, Mrowietz U,. Detection of metabolites of fumaric acid esters in human urine: implications for their mode of action. J Invest Dermatol 2009; 129: 231-4.
    • (2009) J Invest Dermatol , vol.129 , pp. 231-234
    • Rostami-Yazdi, M.1    Clement, B.2    Schmidt, T.J.3    Schinor, D.4    Mrowietz, U.5
  • 4
    • 77955556405 scopus 로고    scopus 로고
    • Pharmacokinetics of anti-psoriatic fumaric acid esters in psoriasis patients
    • Rostami-Yazdi M, Clement B, Mrowietz U,. Pharmacokinetics of anti-psoriatic fumaric acid esters in psoriasis patients. Arch Dermatol Res 2010; 302: 531-8.
    • (2010) Arch Dermatol Res , vol.302 , pp. 531-538
    • Rostami-Yazdi, M.1    Clement, B.2    Mrowietz, U.3
  • 5
    • 68149087714 scopus 로고    scopus 로고
    • Wirksamkeit und Sicherheit von Fumarsäureestern in der Langzeittherapie der Psoriasis - Eine retrospektive Studie (FUTURE)
    • Reich K, Thaci D, Mrowietz U, Kamps A, Neureither M, Luger T,. Wirksamkeit und Sicherheit von Fumarsäureestern in der Langzeittherapie der Psoriasis-Eine retrospektive Studie (FUTURE). J Dtsch Dermatol Ges 2009; 7: 603-11.
    • (2009) J Dtsch Dermatol Ges , vol.7 , pp. 603-611
    • Reich, K.1    Thaci, D.2    Mrowietz, U.3    Kamps, A.4    Neureither, M.5    Luger, T.6
  • 6
    • 2642687679 scopus 로고    scopus 로고
    • Fumaric acid esters suppress peripheral CD4- and CD8-positive lymphocytes in psoriasis
    • Höxtermann S, Nuchel C, Altmeyer P,. Fumaric acid esters suppress peripheral CD4- and CD8-positive lymphocytes in psoriasis. Dermatology 1998; 196: 223-30.
    • (1998) Dermatology , vol.196 , pp. 223-230
    • Höxtermann, S.1    Nuchel, C.2    Altmeyer, P.3
  • 8
    • 33644922923 scopus 로고    scopus 로고
    • Glutathione regulates susceptibility to oxidant-induced mitochondrial DNA damage in human lymphocytes
    • Hollins DL, Suliman HB, Piantadosi CA, Carraway MS,. Glutathione regulates susceptibility to oxidant-induced mitochondrial DNA damage in human lymphocytes. Free Radic Biol Med 2006; 40: 1220-6.
    • (2006) Free Radic Biol Med , vol.40 , pp. 1220-1226
    • Hollins, D.L.1    Suliman, H.B.2    Piantadosi, C.A.3    Carraway, M.S.4
  • 10
    • 0345732760 scopus 로고    scopus 로고
    • Dimethylfumarate is a potent inducer of apoptosis in human T cells
    • Treumer F, Zhu K, Glaser R, Mrowietz U,. Dimethylfumarate is a potent inducer of apoptosis in human T cells. J Invest Dermatol 2003; 121: 1383-8.
    • (2003) J Invest Dermatol , vol.121 , pp. 1383-1388
    • Treumer, F.1    Zhu, K.2    Glaser, R.3    Mrowietz, U.4
  • 12
    • 34247375995 scopus 로고    scopus 로고
    • Dimethylfumarate inhibits nuclear binding of nuclear factor kappaB but not of nuclear factor of activated T cells and CCAAT/enhancer binding protein beta in activated human T cells
    • Gerdes S, Shakery K, Mrowietz U,. Dimethylfumarate inhibits nuclear binding of nuclear factor kappaB but not of nuclear factor of activated T cells and CCAAT/enhancer binding protein beta in activated human T cells. Br J Dermatol 2007; 156: 838-42.
    • (2007) Br J Dermatol , vol.156 , pp. 838-842
    • Gerdes, S.1    Shakery, K.2    Mrowietz, U.3
  • 13
    • 0035725785 scopus 로고    scopus 로고
    • The antipsoriatic drug dimethylfumarate strongly suppresses chemokine production in human keratinocytes and peripheral blood mononuclear cells
    • Stoof TJ, Flier J, Sampat S, Nieboer C, Tensen CP, Boorsma DM,. The antipsoriatic drug dimethylfumarate strongly suppresses chemokine production in human keratinocytes and peripheral blood mononuclear cells. Br J Dermatol 2001; 144: 1114-20.
    • (2001) Br J Dermatol , vol.144 , pp. 1114-1120
    • Stoof, T.J.1    Flier, J.2    Sampat, S.3    Nieboer, C.4    Tensen, C.P.5    Boorsma, D.M.6
  • 14
    • 0031661686 scopus 로고    scopus 로고
    • The antipsoriatic agent dimethylfumarate immunomodulates T-cell cytokine secretion and inhibits cytokines of the psoriatic cytokine network
    • Ockenfels HM, Schultewolter T, Ockenfels G, Funk R, Goos M,. The antipsoriatic agent dimethylfumarate immunomodulates T-cell cytokine secretion and inhibits cytokines of the psoriatic cytokine network. Br J Dermatol 1998; 139: 390-5.
    • (1998) Br J Dermatol , vol.139 , pp. 390-395
    • Ockenfels, H.M.1    Schultewolter, T.2    Ockenfels, G.3    Funk, R.4    Goos, M.5
  • 15
    • 0031800707 scopus 로고    scopus 로고
    • The antipsoriatic dimethyl-fumarate suppresses interferon-gamma -induced ICAM-1 and HLA-DR expression on hyperproliferative keratinocytes. Quantification by a culture plate-directed APAAP-ELISA technique
    • Sebök B, Bonnekoh B, Vetter R, Schneider I, Gollnick H, Mahrle G,. The antipsoriatic dimethyl-fumarate suppresses interferon-gamma -induced ICAM-1 and HLA-DR expression on hyperproliferative keratinocytes. Quantification by a culture plate-directed APAAP-ELISA technique. Eur J Dermatol 1998; 8: 29-32.
    • (1998) Eur J Dermatol , vol.8 , pp. 29-32
    • Sebök, B.1    Bonnekoh, B.2    Vetter, R.3    Schneider, I.4    Gollnick, H.5    Mahrle, G.6
  • 16
    • 34547890303 scopus 로고    scopus 로고
    • Dimethylfumarate specifically inhibits the mitogen and stress-activated kinases 1 and 2 (MSK1/2): Possible role for its anti-psoriatic effect
    • Gesser B, Johansen C, Rasmussen MK, Funding AT, Otkjaer K, Kjellerup RB, Kragballe K, Iversen L,. Dimethylfumarate specifically inhibits the mitogen and stress-activated kinases 1 and 2 (MSK1/2): possible role for its anti-psoriatic effect. J Invest Dermatol 2007; 127: 2129-37.
    • (2007) J Invest Dermatol , vol.127 , pp. 2129-2137
    • Gesser, B.1    Johansen, C.2    Rasmussen, M.K.3    Funding, A.T.4    Otkjaer, K.5    Kjellerup, R.B.6    Kragballe, K.7    Iversen, L.8
  • 17
    • 80051666137 scopus 로고    scopus 로고
    • Dimethylfumarate inhibits MIF-induced proliferation of keratinocytes by inhibiting MSK1 and RSK1 activation and by inducing nuclear p-c-Jun (S63) and p-p53 (S15) expression
    • Gesser B, Rasmussen MK, Raaby L, Rosada C, Johansen C, Kjellerup RB, Kragballe K, Iversen L,. Dimethylfumarate inhibits MIF-induced proliferation of keratinocytes by inhibiting MSK1 and RSK1 activation and by inducing nuclear p-c-Jun (S63) and p-p53 (S15) expression. Inflamm Res 2011; 60: 643-53.
    • (2011) Inflamm Res , vol.60 , pp. 643-653
    • Gesser, B.1    Rasmussen, M.K.2    Raaby, L.3    Rosada, C.4    Johansen, C.5    Kjellerup, R.B.6    Kragballe, K.7    Iversen, L.8
  • 19
    • 0035113357 scopus 로고    scopus 로고
    • Inhibition of dendritic cell differentiation by fumaric acid esters
    • Zhu K, Mrowietz U,. Inhibition of dendritic cell differentiation by fumaric acid esters. J Invest Dermatol 2001; 116: 203-8.
    • (2001) J Invest Dermatol , vol.116 , pp. 203-208
    • Zhu, K.1    Mrowietz, U.2
  • 20
    • 81455154321 scopus 로고    scopus 로고
    • Downregulation of endothelial adhesion molecules by dimethylfumarate, but not monomethylfumarate, and impairment of dynamic lymphocyte-endothelial cell interactions
    • Wallbrecht K, Drick N, Hund AC, Schön MP,. Downregulation of endothelial adhesion molecules by dimethylfumarate, but not monomethylfumarate, and impairment of dynamic lymphocyte-endothelial cell interactions. Exp Dermatol 2011; 20: 980-5.
    • (2011) Exp Dermatol , vol.20 , pp. 980-985
    • Wallbrecht, K.1    Drick, N.2    Hund, A.C.3    Schön, M.P.4
  • 22
    • 74349131119 scopus 로고    scopus 로고
    • Treatment of severe, recalcitrant, chronic plaque psoriasis with fumaric acid esters: A prospective study
    • Wain EM, Darling MI, Pleass RD, Barker JN, Smith CH,. Treatment of severe, recalcitrant, chronic plaque psoriasis with fumaric acid esters: a prospective study. Br J Dermatol 2010; 162: 427-34.
    • (2010) Br J Dermatol , vol.162 , pp. 427-434
    • Wain, E.M.1    Darling, M.I.2    Pleass, R.D.3    Barker, J.N.4    Smith, C.H.5
  • 23
    • 85027958745 scopus 로고    scopus 로고
    • Long-term treatment with fumaric acid esters in an 11-year-old male child with psoriasis
    • Gerdes S, Domm S, Mrowietz U,. Long-term treatment with fumaric acid esters in an 11-year-old male child with psoriasis. Dermatology 2011; 222: 198-200.
    • (2011) Dermatology , vol.222 , pp. 198-200
    • Gerdes, S.1    Domm, S.2    Mrowietz, U.3
  • 24
    • 1242269965 scopus 로고    scopus 로고
    • Erfolgreicher Einsatz von Fumarsäureestern bei einer 14-jährigen Patientin mit Psoriasis vulgaris
    • Günther C, Schmitt J, Wozel G,. Erfolgreicher Einsatz von Fumarsäureestern bei einer 14-jährigen Patientin mit Psoriasis vulgaris. Hautarzt 2004; 15: 28-30.
    • (2004) Hautarzt , vol.15 , pp. 28-30
    • Günther, C.1    Schmitt, J.2    Wozel, G.3
  • 25
    • 77956236570 scopus 로고    scopus 로고
    • Multiple sclerosis: A practical overview for clinicians
    • Rejdak K, Jackson S, Giovannoni G,. Multiple sclerosis: a practical overview for clinicians. Brit Med Bull 2010; 95: 79-104.
    • (2010) Brit Med Bull , vol.95 , pp. 79-104
    • Rejdak, K.1    Jackson, S.2    Giovannoni, G.3
  • 31
    • 79960992155 scopus 로고    scopus 로고
    • Trial watch: Phase III success for Biogen's oral multiple sclerosis therapy
    • Trial watch: Phase III success for Biogen's oral multiple sclerosis therapy. Nat Rev Drug Discov 2011; 10: 404.
    • (2011) Nat Rev Drug Discov , vol.10 , pp. 404
  • 32
    • 33845803652 scopus 로고    scopus 로고
    • Noninfectious granulomatous diseases: An update
    • Izikson L, English JC,. Noninfectious granulomatous diseases: an update. Adv Dermatol 2006; 22: 31-53.
    • (2006) Adv Dermatol , vol.22 , pp. 31-53
    • Izikson, L.1    English, J.C.2
  • 35
    • 21644463999 scopus 로고    scopus 로고
    • Therapy of noninfectious granulomatous skin diseases with fumaric acid esters
    • Breuer K, Gutzmer R, Volker B, Kapp A, Werfel T,. Therapy of noninfectious granulomatous skin diseases with fumaric acid esters. Brit J Dermatol 2005; 152: 1290-5.
    • (2005) Brit J Dermatol , vol.152 , pp. 1290-1295
    • Breuer, K.1    Gutzmer, R.2    Volker, B.3    Kapp, A.4    Werfel, T.5
  • 36
    • 76349094277 scopus 로고    scopus 로고
    • Fumaric acid esters in severe ulcerative necrobiosis lipoidica: A case report and evaluation of current therapies
    • Eberle FC, Ghoreschi K, Hertl M,. Fumaric acid esters in severe ulcerative necrobiosis lipoidica: a case report and evaluation of current therapies. Acta Derm-Venereol 2010; 90: 104-6.
    • (2010) Acta Derm-Venereol , vol.90 , pp. 104-106
    • Eberle, F.C.1    Ghoreschi, K.2    Hertl, M.3
  • 37
    • 33751216455 scopus 로고    scopus 로고
    • Diagnosis and management of granuloma annulare
    • Cyr PR,. Diagnosis and management of granuloma annulare. Am Fam Physician 2006; 74: 1729-34.
    • (2006) Am Fam Physician , vol.74 , pp. 1729-1734
    • Cyr, P.R.1
  • 38
    • 0033623408 scopus 로고    scopus 로고
    • Expression of IFN gamma, coexpression of TNF alpha and matrix metalloproteinases and apoptosis of T lymphocytes and macrophages in granuloma annulare
    • Fayyazi A, Schweyer S, Eichmeyer B, Herms J, Hemmerlein B, Radzun HJ, Berger H,. Expression of IFN gamma, coexpression of TNF alpha and matrix metalloproteinases and apoptosis of T lymphocytes and macrophages in granuloma annulare. Archives of Dermatological Research 2000; 292: 384-90.
    • (2000) Archives of Dermatological Research , vol.292 , pp. 384-390
    • Fayyazi, A.1    Schweyer, S.2    Eichmeyer, B.3    Herms, J.4    Hemmerlein, B.5    Radzun, H.J.6    Berger, H.7
  • 40
    • 66749127919 scopus 로고    scopus 로고
    • Treatment of disseminated granuloma annulare with low-dose fumaric acid
    • Weber HO, Borelli C, Röcken M, Schaller M,. Treatment of disseminated granuloma annulare with low-dose fumaric acid. Acta Derm Venereol 2009; 89: 295-8.
    • (2009) Acta Derm Venereol , vol.89 , pp. 295-298
    • Weber, H.O.1    Borelli, C.2    Röcken, M.3    Schaller, M.4
  • 41
    • 0035106539 scopus 로고    scopus 로고
    • Granuloma annulare disseminatum: Erfolgreiche Therapie mit Fumarsäurester
    • Schulze-Dirks A, Petzoldt D,. Granuloma annulare disseminatum: erfolgreiche Therapie mit Fumarsäurester. Hautarzt 2001; 52: 228-30.
    • (2001) Hautarzt , vol.52 , pp. 228-230
    • Schulze-Dirks, A.1    Petzoldt, D.2
  • 42
    • 84866257378 scopus 로고    scopus 로고
    • Treatment of disseminated granuloma annulare recalcitrant to topical therapy: A retrospective 10-year analysis with comparison of photochemotherapy alone versus photochemotherapy plus oral fumaric acid esters
    • doi: 10.1111/j.1468-3083.2011.04320.x [Epub ahead of print]
    • Wollina U, Langner D,. Treatment of disseminated granuloma annulare recalcitrant to topical therapy: a retrospective 10-year analysis with comparison of photochemotherapy alone versus photochemotherapy plus oral fumaric acid esters. J Eur Acad Dermatol Venereol 2011; doi: 10.1111/j.1468-3083.2011. 04320.x [Epub ahead of print].
    • (2011) J Eur Acad Dermatol Venereol
    • Wollina, U.1    Langner, D.2
  • 44
    • 2942586808 scopus 로고    scopus 로고
    • Successful treatment of recalcitrant cutaneous sarcoidosis with fumaric acid esters
    • Nowack U, Gambichler T, Hanefeld C, Kastner U, Altmeyer P,. Successful treatment of recalcitrant cutaneous sarcoidosis with fumaric acid esters. BMC Dermatol 2002; 2: 15.
    • (2002) BMC Dermatol , vol.2 , pp. 15
    • Nowack, U.1    Gambichler, T.2    Hanefeld, C.3    Kastner, U.4    Altmeyer, P.5
  • 45
    • 3042521447 scopus 로고    scopus 로고
    • Erfolgreiche Therapie einer Haut- und Lungensarkoidose mit Fumarsäureestern
    • Gutzmer R, Kapp A, Werfel T,. Erfolgreiche Therapie einer Haut- und Lungensarkoidose mit Fumarsäureestern. Hautarzt 2004; 55: 553-7.
    • (2004) Hautarzt , vol.55 , pp. 553-557
    • Gutzmer, R.1    Kapp, A.2    Werfel, T.3
  • 46
    • 84857193135 scopus 로고    scopus 로고
    • Fumarsäureestertherapie bei einer jungen Patientin mit ausgeprägter Cheilitis granulomatosa
    • Kleine R, Brohl L, Amon U,. Fumarsäureestertherapie bei einer jungen Patientin mit ausgeprägter Cheilitis granulomatosa. Hautarzt 2011; 62: 940-2.
    • (2011) Hautarzt , vol.62 , pp. 940-942
    • Kleine, R.1    Brohl, L.2    Amon, U.3
  • 47
    • 79952842066 scopus 로고    scopus 로고
    • Treatment of recurrent aphthous stomatitis with fumaric acid esters
    • Guenova E, Hötzenecker W,. Treatment of recurrent aphthous stomatitis with fumaric acid esters. Arch Dermatol 2011; 147: 282-4.
    • (2011) Arch Dermatol , vol.147 , pp. 282-284
    • Guenova, E.1    Hötzenecker, W.2
  • 49
    • 34247155666 scopus 로고    scopus 로고
    • Improvement of noninfectious uveitis with fumaric acid esters: Results of a pilot study
    • Heinz C, Heiligenhaus A,. Improvement of noninfectious uveitis with fumaric acid esters: results of a pilot study. Arch Ophthalmol 2007; 125: 569-71.
    • (2007) Arch Ophthalmol , vol.125 , pp. 569-571
    • Heinz, C.1    Heiligenhaus, A.2
  • 50
    • 0023877990 scopus 로고
    • Toxic effects of acute glutathione depletion by buthionine sulfoximine and dimethylfumarate on murine mammary carcinoma cells
    • Dethlefsen LA, Lehman CM, Biaglow JE, Peck VM,. Toxic effects of acute glutathione depletion by buthionine sulfoximine and dimethylfumarate on murine mammary carcinoma cells. Radiat Res 1988; 114: 215-24.
    • (1988) Radiat Res , vol.114 , pp. 215-224
    • Dethlefsen, L.A.1    Lehman, C.M.2    Biaglow, J.E.3    Peck, V.M.4
  • 51
    • 0032882988 scopus 로고    scopus 로고
    • Dietary compounds that induce cancer preventive phase 2 enzymes activate apoptosis at comparable doses in HT29 colon carcinoma cells
    • Kirlin WG, Cai J, DeLong MJ, Patten EJ, Jones DP,. Dietary compounds that induce cancer preventive phase 2 enzymes activate apoptosis at comparable doses in HT29 colon carcinoma cells. J Nutr 1999; 129: 1827-35.
    • (1999) J Nutr , vol.129 , pp. 1827-1835
    • Kirlin, W.G.1    Cai, J.2    Delong, M.J.3    Patten, E.J.4    Jones, D.P.5
  • 52
    • 13844281108 scopus 로고    scopus 로고
    • Enhanced cytotoxicity of bioreductive antitumor agents with dimethyl fumarate in human glioblastoma cells
    • Gu B, DeAngelis LM,. Enhanced cytotoxicity of bioreductive antitumor agents with dimethyl fumarate in human glioblastoma cells. Anticancer Drugs 2005; 16: 167-74.
    • (2005) Anticancer Drugs , vol.16 , pp. 167-174
    • Gu, B.1    Deangelis, L.M.2
  • 53
    • 79251613647 scopus 로고    scopus 로고
    • Transient alteration of cellular redox buffering before irradiation triggers apoptosis in head and neck carcinoma stem and non-stem cells
    • Boivin A, Hanot M, Malesys C, Maalouf M, Rousson R, Rodriguez-Lafrasse C, Ardail D,. Transient alteration of cellular redox buffering before irradiation triggers apoptosis in head and neck carcinoma stem and non-stem cells. PLoS One 2011; 6: e14558.
    • (2011) PLoS One , vol.6
    • Boivin, A.1    Hanot, M.2    Malesys, C.3    Maalouf, M.4    Rousson, R.5    Rodriguez-Lafrasse, C.6    Ardail, D.7
  • 57
    • 0037415596 scopus 로고    scopus 로고
    • Immunotherapy of cytotoxic T cell-resistant tumors by T helper 2 cells: An eotaxin and STAT6-dependent process
    • Mattes J, Hulett M, Xie W, Hogan S, Rothenberg ME, Foster P, Parish C,. Immunotherapy of cytotoxic T cell-resistant tumors by T helper 2 cells: an eotaxin and STAT6-dependent process. J Exp Med 2003; 197: 387-93.
    • (2003) J Exp Med , vol.197 , pp. 387-393
    • Mattes, J.1    Hulett, M.2    Xie, W.3    Hogan, S.4    Rothenberg, M.E.5    Foster, P.6    Parish, C.7
  • 58
    • 0027310177 scopus 로고
    • Posttranscriptional down-regulation of ras oncogene expression by inhibitors of cellular glutathione
    • Miller AC, Gafner J, Clark EP, Samid D,. Posttranscriptional down-regulation of ras oncogene expression by inhibitors of cellular glutathione. Mol Cell Biol 1993; 13: 4416-22.
    • (1993) Mol Cell Biol , vol.13 , pp. 4416-4422
    • Miller, A.C.1    Gafner, J.2    Clark, E.P.3    Samid, D.4
  • 59
    • 79952207507 scopus 로고    scopus 로고
    • Malignant melanoma during treatment with fumaric acid esters - Coincidence or treatment-related
    • Barth D, Simon JC, Wetzig T,. Malignant melanoma during treatment with fumaric acid esters-coincidence or treatment-related J Dtsch Dermatol Ges 2011; 9: 223-5.
    • (2011) J Dtsch Dermatol Ges , vol.9 , pp. 223-225
    • Barth, D.1    Simon, J.C.2    Wetzig, T.3
  • 60
    • 70449473464 scopus 로고    scopus 로고
    • Squamous cell carcinoma as a complication of fumaric acid ester immunosuppression
    • Jennings L, Murphy G,. Squamous cell carcinoma as a complication of fumaric acid ester immunosuppression. J Eur Acad Dermatol Venereol 2009; 23: 1451.
    • (2009) J Eur Acad Dermatol Venereol , vol.23 , pp. 1451
    • Jennings, L.1    Murphy, G.2
  • 63
    • 81455135889 scopus 로고    scopus 로고
    • Dimethyl fumarate, an immune modulator and inducer of the antioxidant response, suppresses HIV replication and macrophage-mediated neurotoxicity: A novel candidate for HIV neuroprotection
    • Cross SA, Cook DR, Chi AW, Vance PJ, Kolson LL, Wong BJ, Jordan-Sciutto KL, Kolson DL,. Dimethyl fumarate, an immune modulator and inducer of the antioxidant response, suppresses HIV replication and macrophage-mediated neurotoxicity: a novel candidate for HIV neuroprotection. J Immunol 2011; 187: 5015-25.
    • (2011) J Immunol , vol.187 , pp. 5015-5025
    • Cross, S.A.1    Cook, D.R.2    Chi, A.W.3    Vance, P.J.4    Kolson, L.L.5    Wong, B.J.6    Jordan-Sciutto, K.L.7    Kolson, D.L.8
  • 64
    • 77958010498 scopus 로고    scopus 로고
    • DMF inhibits PDGF-BB induced airway smooth muscle cell proliferation through induction of heme-oxygenase-1
    • Seidel P, Goulet S, Hostettler K, Tamm M, Roth M,. DMF inhibits PDGF-BB induced airway smooth muscle cell proliferation through induction of heme-oxygenase-1. Respir Res 2010; 11: 145.
    • (2010) Respir Res , vol.11 , pp. 145
    • Seidel, P.1    Goulet, S.2    Hostettler, K.3    Tamm, M.4    Roth, M.5
  • 66
    • 67651236354 scopus 로고    scopus 로고
    • Dimethylfumarate inhibits NF-I°B function at multiple levels to limit airway smooth muscle cell cytokine secretion
    • Seidel P, Merfort I, Hughes JM, Oliver BG, Tamm M, Roth M,. Dimethylfumarate inhibits NF-I°B function at multiple levels to limit airway smooth muscle cell cytokine secretion. Am J Physiol Lung Cell Mol Physiol 2009; 297: 326-39.
    • (2009) Am J Physiol Lung Cell Mol Physiol , vol.297 , pp. 326-339
    • Seidel, P.1    Merfort, I.2    Hughes, J.M.3    Oliver, B.G.4    Tamm, M.5    Roth, M.6


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