Inhibition of DPP-4 reduces acute mortality after myocardial infarction with restoration of autophagic response in type 2 diabetic rats

Cardiovascular Diabetology

Volumn 14, Issue 1, 2015, Pages

  Murase, Hiromichi ^a   Kuno, Atsushi ^a   Miki, Takayuki ^a   Tanno, Masaya ^a   Yano, Toshiyuki ^a   Kouzu, Hidemichi ^a   Ishikawa, Satoko ^a   Tobisawa, Toshiyuki ^a   Ogasawara, Makoto ^a   Nishizawa, Keitaro ^a   Miura, Tetsuji ^a  

^a SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Autophagy; DPP 4 inhibitor; Mortality; Myocardial infarction; Type 2 diabetes

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; ADENYLATE KINASE; BECLIN 1; CHLOROQUINE; DIPEPTIDYL PEPTIDASE IV; EXENDIN 4; GLUCAGON LIKE PEPTIDE 1; LC3 II PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; PEPTIDES AND PROTEINS; PROTEIN BCL 2; PROTEIN KINASE B; PROTEIN S6; ULK 1 PROTEIN; UNCLASSIFIED DRUG; VILDAGLIPTIN; VINCULIN; ADAMANTANE; APOPTOSIS REGULATORY PROTEIN; BECN1 PROTEIN, RAT; DIPEPTIDYL PEPTIDASE IV INHIBITOR; DPP4 PROTEIN, RAT; LC3 PROTEIN, RAT; MICROTUBULE ASSOCIATED PROTEIN; NITRILE; PYRROLIDINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; BLOOD PRESSURE; CARDIOVASCULAR MORTALITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GLUCOSE BLOOD LEVEL; HEART INFARCTION; HEART INFARCTION SIZE; HEART LEFT VENTRICLE CONTRACTION; HEART LEFT VENTRICLE EJECTION FRACTION; HEART PROTECTION; HEART RATE; INSULIN BLOOD LEVEL; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PROTEIN PROTEIN INTERACTION; RAT; SURVIVAL RATE; ANALOGS AND DERIVATIVES; ANIMAL; BLOOD; CARDIAC MUSCLE; DIABETES MELLITUS, TYPE 2; DISEASE MODEL; DRUG ADMINISTRATION; DRUG EFFECTS; ENZYMOLOGY; HEART LEFT VENTRICLE FUNCTION; METABOLISM; MYOCARDIAL INFARCTION; OTSUKA LONG EVANS TOKUSHIMA FATTY RAT; PATHOLOGY; PATHOPHYSIOLOGY; SIGNAL TRANSDUCTION; SUBCUTANEOUS DRUG ADMINISTRATION; TIME FACTOR;

ADAMANTANE; ANIMALS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; BECLIN-1; CHLOROQUINE; DIABETES MELLITUS, TYPE 2; DIPEPTIDYL PEPTIDASE 4; DIPEPTIDYL-PEPTIDASE IV INHIBITORS; DISEASE MODELS, ANIMAL; DRUG ADMINISTRATION SCHEDULE; INJECTIONS, SUBCUTANEOUS; MALE; MICROTUBULE-ASSOCIATED PROTEINS; MYOCARDIAL INFARCTION; MYOCARDIUM; NITRILES; PROTO-ONCOGENE PROTEINS C-BCL-2; PYRROLIDINES; RATS, INBRED OLETF; SIGNAL TRANSDUCTION; TIME FACTORS; VENTRICULAR FUNCTION, LEFT;

EID: 84938791685     PISSN: None     EISSN: 14752840     Source Type: Journal    
DOI: 10.1186/s12933-015-0264-6     Document Type: Article

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