-
1
-
-
64049088018
-
Spindle orientation during asymmetric cell division
-
Siller, K. H. & Doe, C. Q. Spindle orientation during asymmetric cell division. Nat. Cell Biol. 11, 365-374 (2009
-
(2009)
Nat. Cell Biol
, vol.11
, pp. 365-374
-
-
Siller, K.H.1
Doe, C.Q.2
-
2
-
-
78649439321
-
Asymmetric cell division: Recent developments and their implications for tumour biology
-
Knoblich, J. A. Asymmetric cell division: recent developments and their implications for tumour biology. Nat. Rev. Mol. Cell Biol. 11, 849-860 (2010
-
(2010)
Nat. Rev. Mol. Cell Biol
, vol.11
, pp. 849-860
-
-
Knoblich, J.A.1
-
3
-
-
84875993287
-
Molecular pathways regulating mitotic spindle orientation in animal cells
-
Lu, M. S. & Johnston, C. A. Molecular pathways regulating mitotic spindle orientation in animal cells. Development 140, 1843-1856 (2013
-
(2013)
Development
, vol.140
, pp. 1843-1856
-
-
Lu, M.S.1
Johnston, C.A.2
-
4
-
-
33947596005
-
Integrin-mediated adhesion orients the spindle parallel to the substratum in an EB1-And myosin X-dependent manner
-
Toyoshima, F. & Nishida, E. Integrin-mediated adhesion orients the spindle parallel to the substratum in an EB1-And myosin X-dependent manner. EMBO J. 26, 1487-1498 (2007
-
(2007)
EMBO J.
, vol.26
, pp. 1487-1498
-
-
Toyoshima, F.1
Nishida, E.2
-
5
-
-
70149120831
-
Identification of an Aurora-A/PinsLINKER/ dlg spindle orientation pathway using induced cell polarity in S2 cells
-
Johnston, C. A., Hirono, K., Prehoda, K. E. & Doe, C. Q. Identification of an Aurora-A/PinsLINKER/ dlg spindle orientation pathway using induced cell polarity in S2 cells. Cell 138, 1150-1163 (2009
-
(2009)
Cell
, vol.138
, pp. 1150-1163
-
-
Johnston, C.A.1
Hirono, K.2
Prehoda, K.E.3
Doe, C.Q.4
-
6
-
-
84887625953
-
Mechanisms of spindle positioning: Cortical force generators in the limelight
-
Kotak, S. & Gönczy, P. Mechanisms of spindle positioning: cortical force generators in the limelight. Curr. Opin. Cell Biol. 25, 741-748 (2013
-
(2013)
Curr. Opin. Cell Biol
, vol.25
, pp. 741-748
-
-
Kotak, S.1
Gönczy, P.2
-
7
-
-
0028879986
-
Nucleation of microtubule assembly by a-Tubulin-containing ring complex
-
Zheng, Y., Wong, M. L., Alberts, B. & Mitchison, T. Nucleation of microtubule assembly by a-Tubulin-containing ring complex. Nature 378, 578-583 (1995
-
(1995)
Nature
, vol.378
, pp. 578-583
-
-
Zheng, Y.1
Wong, M.L.2
Alberts, B.3
Mitchison, T.4
-
8
-
-
0028973450
-
Microtubule nucleation by-Tubulin-containing rings in the centrosome
-
Moritz, M., Braunfeld, M. B., Sedat, J. W., Alberts, B. & Agard, D. A. Microtubule nucleation by-Tubulin-containing rings in the centrosome. Nature 378, 638-640 (1995
-
(1995)
Nature
, vol.378
, pp. 638-640
-
-
Moritz, M.1
Braunfeld, M.B.2
Sedat, J.W.3
Alberts, B.4
Agard, D.A.5
-
9
-
-
80054901400
-
Microtubule nucleation by-Tubulin complexes
-
Kollman, J. M., Merdes, A., Mourey, L. & Agard, D. A. Microtubule nucleation by-Tubulin complexes. Nat. Rev. Mol. Cell Biol. 12, 709-721 (2011
-
(2011)
Nat. Rev. Mol. Cell Biol
, vol.12
, pp. 709-721
-
-
Kollman, J.M.1
Merdes, A.2
Mourey, L.3
Agard, D.A.4
-
10
-
-
84872191338
-
The where, when and how of microtubule nucleation-one ring to rule them all
-
Teixidó-Travesa, N., Roig, J. & Lüders, J. The where, when and how of microtubule nucleation-one ring to rule them all. J. Cell Sci. 125, 4445-4456 (2012
-
(2012)
J. Cell Sci
, vol.125
, pp. 4445-4456
-
-
Teixidó-Travesa, N.1
Roig, J.2
Lüders, J.3
-
11
-
-
84856290771
-
The centrosome in cells and organisms
-
Bornens, M. The centrosome in cells and organisms. Science 335, 422-426 (2012
-
(2012)
Science
, vol.335
, pp. 422-426
-
-
Bornens, M.1
-
12
-
-
43049151493
-
Polo on the rise-from mitotic entry to cytokinesis with Plk1
-
Petronczki, M., Lénárt, P. & Peters, J.-M. Polo on the rise-from mitotic entry to cytokinesis with Plk1. Dev. Cell 14, 646-659 (2008
-
(2008)
Dev. Cell
, vol.14
, pp. 646-659
-
-
Petronczki, M.1
Lénárt, P.2
Peters, J.-M.3
-
13
-
-
62849123093
-
Polo-like kinases: Conservation and divergence in their functions and regulation
-
Archambault, V. & Glover, D. M. Polo-like kinases: conservation and divergence in their functions and regulation. Nat. Rev. Mol. Cell Biol. 10, 265-275 (2009
-
(2009)
Nat. Rev. Mol. Cell Biol
, vol.10
, pp. 265-275
-
-
Archambault, V.1
Glover, D.M.2
-
14
-
-
84870061337
-
Switching Polo-like kinase-1 on and off in time and space
-
Bruinsma, W., Raaijmakers, J. A. & Medema, R. H. Switching Polo-like kinase-1 on and off in time and space. Trends Biochem. Sci. 37, 534-542 (2012
-
(2012)
Trends Biochem. Sci
, vol.37
, pp. 534-542
-
-
Bruinsma, W.1
Raaijmakers, J.A.2
Medema, R.H.3
-
15
-
-
54749133489
-
A genome-wide RNAi screen to dissect centriole duplication and centrosome maturation in Drosophila
-
Dobbelaere, J. et al. A genome-wide RNAi screen to dissect centriole duplication and centrosome maturation in Drosophila. PLoS Biol. 6, e224 (2008
-
(2008)
PLoS Biol
, vol.6
, pp. e224
-
-
Dobbelaere, J.1
-
16
-
-
38349078475
-
Cep68 and Cep215 (Cdk5rap2) are required for centrosome cohesion
-
Graser, S., Stierhof, Y.-D. & Nigg, E. A. Cep68 and Cep215 (Cdk5rap2) are required for centrosome cohesion. J. Cell Sci. 120, 4321-4331 (2007
-
(2007)
J. Cell Sci
, vol.120
, pp. 4321-4331
-
-
Graser, S.1
Stierhof, Y.-D.2
Nigg, E.A.3
-
17
-
-
38749152785
-
CDK5RAP2 is a pericentriolar protein that functions in centrosomal attachment of the-Tubulin ring complex
-
Fong, K.-W., Choi, Y.-K., Rattner, J. B. & Qi, R. Z. CDK5RAP2 is a pericentriolar protein that functions in centrosomal attachment of the-Tubulin ring complex. Mol. Biol. Cell 19, 115-125 (2008
-
(2008)
Mol. Biol. Cell
, vol.19
, pp. 115-125
-
-
Fong, K.-W.1
Choi, Y.-K.2
Rattner, J.B.3
Qi, R.Z.4
-
18
-
-
79960921403
-
Cdk5rap2 exposes the centrosomal root of microcephaly syndromes
-
Megraw, T. L., Sharkey, J. T. & Nowakowski, R. S. Cdk5rap2 exposes the centrosomal root of microcephaly syndromes. Trends Cell Biol. 21, 470-480 (2011
-
(2011)
Trends Cell Biol
, vol.21
, pp. 470-480
-
-
Megraw, T.L.1
Sharkey, J.T.2
Nowakowski, R.S.3
-
19
-
-
77958462847
-
A Wnt signalling component, is involved in mitotic progression in cooperation with Plk1
-
Kikuchi, K., Niikura, Y., Kitagawa, K. & Kikuchi, A. Dishevelled, a Wnt signalling component, is involved in mitotic progression in cooperation with Plk1. EMBO J. 29, 3470-3483 (2010
-
(2010)
EMBO J.
, vol.29
, pp. 3470-3483
-
-
Kikuchi, K.1
Niikura, Y.2
Kitagawa, K.3
Dishevelled, K.A.4
-
20
-
-
77952201222
-
Cdk5rap2 regulates centrosome function and chromosome segregation in neuronal progenitors
-
Lizarraga, S. B. et al. Cdk5rap2 regulates centrosome function and chromosome segregation in neuronal progenitors. Development 137, 1907-1917 (2010
-
(2010)
Development
, vol.137
, pp. 1907-1917
-
-
Lizarraga, S.B.1
-
21
-
-
84857788913
-
Chromosome-And spindle-pole-derived signals generate an intrinsic code for spindle position and orientation
-
Kiyomitsu, T. & Cheeseman, I. M. Chromosome-And spindle-pole-derived signals generate an intrinsic code for spindle position and orientation. Nat. Cell Biol. 14, 311-317 (2012
-
(2012)
Nat. Cell Biol
, vol.14
, pp. 311-317
-
-
Kiyomitsu, T.1
Cheeseman, I.M.2
-
22
-
-
84876330632
-
MISP is a novel Plk1 substrate required for proper spindle orientation and mitotic progression
-
Zhu, M. et al. MISP is a novel Plk1 substrate required for proper spindle orientation and mitotic progression. J. Cell Biol. 200, 773-787 (2013
-
(2013)
J. Cell Biol
, vol.200
, pp. 773-787
-
-
Zhu, M.1
-
23
-
-
84897030805
-
The centrosome-specific phosphorylation of Cnn by Polo/Plk1 drives cnn scaffold assembly and centrosome maturation
-
Conduit, P. T. et al. The centrosome-specific phosphorylation of Cnn by Polo/Plk1 drives cnn scaffold assembly and centrosome maturation. Dev. Cell 28, 659-669 (2014
-
(2014)
Dev. Cell
, vol.28
, pp. 659-669
-
-
Conduit, P.T.1
-
24
-
-
84863046015
-
ABL1 regulates spindle orientation in adherent cells and mammalian skin
-
Matsumura, S. et al. ABL1 regulates spindle orientation in adherent cells and mammalian skin. Nat. Commun. 3, 626 (2012
-
(2012)
Nat. Commun
, vol.3
, pp. 626
-
-
Matsumura, S.1
-
26
-
-
78751627951
-
Leucine-rich repeat kinase LRRK1 regulates endosomal trafficking of the EGF receptor
-
Hanafusa, H. et al. Leucine-rich repeat kinase LRRK1 regulates endosomal trafficking of the EGF receptor. Nat. Commun. 2, 158 (2011
-
(2011)
Nat. Commun
, vol.2
, pp. 158
-
-
Hanafusa, H.1
-
27
-
-
84859415103
-
EGFR-dependent phosphorylation of leucine-rich repeat kinase LRRK1 is important for proper endosomal trafficking of EGFR
-
Ishikawa, K., Nara, A., Matsumoto, K. & Hanafusa, H. EGFR-dependent phosphorylation of leucine-rich repeat kinase LRRK1 is important for proper endosomal trafficking of EGFR. Mol. Biol. Cell 23, 1294-1306 (2012
-
(2012)
Mol. Biol. Cell
, vol.23
, pp. 1294-1306
-
-
Ishikawa, K.1
Nara, A.2
Matsumoto, K.3
Hanafusa, H.4
-
28
-
-
84921396317
-
LRRK1-phosphorylated CLIP-170 regulates EGFR trafficking by recruiting p150Glued to microtubule plus ends
-
Kedashiro, S. et al. LRRK1-phosphorylated CLIP-170 regulates EGFR trafficking by recruiting p150Glued to microtubule plus ends. J. Cell Sci. 128, 385-396 (2015
-
(2015)
J. Cell Sci
, vol.128
, pp. 385-396
-
-
Kedashiro, S.1
-
29
-
-
0029993727
-
Active and inactive protein kinases: Structural basis for regulation
-
Johnson, L. N., Noble, M. E. M. & Owen, D. J. Active and inactive protein kinases: structural basis for regulation. Cell 85, 149-158 (1996
-
(1996)
Cell
, vol.85
, pp. 149-158
-
-
Johnson, L.N.1
Noble, M.E.M.2
Owen, D.J.3
-
31
-
-
10744221449
-
The molecular basis for phosphodependent substrate targeting and regulation of Plks by the Polo-box domain
-
Elia, A. E. H. et al. The molecular basis for phosphodependent substrate targeting and regulation of Plks by the Polo-box domain. Cell 115, 83-95 (2003
-
(2003)
Cell
, vol.115
, pp. 83-95
-
-
Elia, A.E.H.1
-
32
-
-
0242556820
-
The crystal structure of the human polo-like kinase-1 polo box domain and its phospho-peptide complex
-
Cheng, K.-Y., Lowe, E. D., Sinclair, J., Nigg, E. A. & Johnson, L. N. The crystal structure of the human polo-like kinase-1 polo box domain and its phospho-peptide complex. EMBO J. 22, 5757-5768 (2003
-
(2003)
EMBO J.
, vol.22
, pp. 5757-5768
-
-
Cheng, K.-Y.1
Lowe, E.D.2
Sinclair, J.3
Nigg, E.A.4
Johnson, L.N.5
-
33
-
-
33846931644
-
The small-molecule inhibitor BI 2536 reveals novel insights into mitotic roles of polo-like kinase 1
-
Lénárt, P. et al. The small-molecule inhibitor BI 2536 reveals novel insights into mitotic roles of polo-like kinase 1. Curr. Biol. 17, 304-315 (2007
-
(2007)
Curr. Biol
, vol.17
, pp. 304-315
-
-
Lénárt, P.1
-
34
-
-
33846933218
-
BI 2536, a potent and selective inhibitor of polo-like kinase 1, inhibits tumor growth in vivo
-
Steegmaier, M. et al. BI 2536, a potent and selective inhibitor of polo-like kinase 1, inhibits tumor growth in vivo. Curr. Biol. 17, 316-322 (2007
-
(2007)
Curr. Biol
, vol.17
, pp. 316-322
-
-
Steegmaier, M.1
-
35
-
-
4644266184
-
Roles of polo-like kinase 1 in the assembly of functional mitotic spindles
-
Sumara, I. et al. Roles of polo-like kinase 1 in the assembly of functional mitotic spindles. Curr. Biol. 14, 1712-1722 (2004
-
(2004)
Curr. Biol
, vol.14
, pp. 1712-1722
-
-
Sumara, I.1
-
36
-
-
0033615357
-
Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen
-
Mayer, T. U. et al. Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen. Science 286, 971-974 (1999
-
(1999)
Science
, vol.286
, pp. 971-974
-
-
Mayer, T.U.1
-
37
-
-
33746094659
-
Selective small-molecule inhibitor reveals critical mitotic functions of human CDK1
-
Vassilev, L. T. et al. Selective small-molecule inhibitor reveals critical mitotic functions of human CDK1. Proc. Natl Acad. Sci. USA 103, 10660-10665 (2006
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 10660-10665
-
-
Vassilev, L.T.1
-
38
-
-
36448980590
-
PtdIns 3 4, 5)P3 regulates spindle orientation in adherent cells
-
Toyoshima, F., Matsumura, S., Morimoto, H., Mitsushima, M. & Nishida, E. PtdIns(3, 4, 5)P3 regulates spindle orientation in adherent cells. Dev. Cell 13, 796-811 (2007
-
(2007)
Dev. Cell
, vol.13
, pp. 796-811
-
-
Toyoshima, F.1
Matsumura, S.2
Morimoto, H.3
Mitsushima, M.4
Nishida, E.5
-
39
-
-
78650115459
-
CDK5RAP2 stimulates microtubule nucleation by the-Tubulin ring complex
-
Choi, Y.-K., Liu, P., Sze, S. K., Dai, C. & Qi, R. Z. CDK5RAP2 stimulates microtubule nucleation by the-Tubulin ring complex. J. Cell Biol. 191, 1089-1095 (2010
-
(2010)
J. Cell Biol
, vol.191
, pp. 1089-1095
-
-
Choi, Y.-K.1
Liu, P.2
Sze, S.K.3
Dai, C.4
Qi, R.Z.5
-
40
-
-
34948859423
-
Proper recruitment of-Tubulin and D-TACC/Msps to embryonic Drosophila centrosomes requires centrosomin motif 1
-
Zhang, J. & Megraw, T. L. Proper recruitment of-Tubulin and D-TACC/Msps to embryonic Drosophila centrosomes requires centrosomin motif 1. Mol. Biol. Cell 18, 4037-4049 (2007
-
(2007)
Mol. Biol. Cell
, vol.18
, pp. 4037-4049
-
-
Zhang, J.1
Megraw, T.L.2
-
41
-
-
77954615930
-
Conserved motif of CDK5RAP2 mediates its localization to centrosomes and the Golgi complex
-
Wang, Z. et al. Conserved motif of CDK5RAP2 mediates its localization to centrosomes and the Golgi complex. J. Biol. Chem. 285, 22658-22665 (2010
-
(2010)
J. Biol. Chem
, vol.285
, pp. 22658-22665
-
-
Wang, Z.1
-
42
-
-
33244490241
-
Complex formation of Plk1 and INCENP required for metaphase- Anaphase transition
-
Goto, H. et al. Complex formation of Plk1 and INCENP required for metaphase- Anaphase transition. Nat. Cell Biol. 8, 180-187 (2006
-
(2006)
Nat. Cell Biol
, vol.8
, pp. 180-187
-
-
Goto, H.1
-
43
-
-
36349025888
-
Cdk1 phosphorylation of BubR1 controls spindle checkpoint arrest and Plk1-mediated formation of the 3F3/2 epitope
-
Wong, O. K. & Fang, G. Cdk1 phosphorylation of BubR1 controls spindle checkpoint arrest and Plk1-mediated formation of the 3F3/2 epitope. J. Cell Biol. 179, 611-617 (2007
-
(2007)
J. Cell Biol
, vol.179
, pp. 611-617
-
-
Wong, O.K.1
Fang, G.2
-
44
-
-
8844266996
-
Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease
-
Paisán-Ruíz, C. et al. Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease. Neuron 44, 595-600 (2004
-
(2004)
Neuron
, vol.44
, pp. 595-600
-
-
Paisán-Ruíz, C.1
-
45
-
-
8844233579
-
Mutations in LRRK2 cause autosomal-dominant Parkinsonism with pleomorphic pathology
-
Zimprich, A. et al. Mutations in LRRK2 cause autosomal-dominant Parkinsonism with pleomorphic pathology. Neuron 44, 601-607 (2004
-
(2004)
Neuron
, vol.44
, pp. 601-607
-
-
Zimprich, A.1
-
46
-
-
0035936578
-
Zygotic development without functional mitotic centrosomes
-
Megraw, T. L., Kao, L.-R. & Kaufman, T. C. Zygotic development without functional mitotic centrosomes. Curr. Biol. 11, 116-120 (2001
-
(2001)
Curr. Biol
, vol.11
, pp. 116-120
-
-
Megraw, T.L.1
Kao, L.-R.2
Kaufman, T.C.3
-
47
-
-
77649258853
-
NudC-like protein 2 regulates the LIS1/dynein pathway by stabilizing LIS1 with Hsp90
-
Yang, Y. et al. NudC-like protein 2 regulates the LIS1/dynein pathway by stabilizing LIS1 with Hsp90. Proc. Natl Acad. Sci. USA 107, 3499-3504 (2010
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 3499-3504
-
-
Yang, Y.1
-
48
-
-
0038492408
-
Identification of a consensus motif for Plk (polo-like kinase) phosphorylation reveals Myt1 as a Plk1 substrate
-
Nakajima, H., Toyoshima-Morimoto, F., Taniguchi, E. & Nishida, E. Identification of a consensus motif for Plk (polo-like kinase) phosphorylation reveals Myt1 as a Plk1 substrate. J. Biol. Chem. 278, 25277-25280 (2003
-
(2003)
J. Biol. Chem
, vol.278
, pp. 25277-25280
-
-
Nakajima, H.1
Toyoshima-Morimoto, F.2
Taniguchi, E.3
Nishida, E.4
|