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Volumn 464, Issue 3, 2015, Pages 748-754

MicroRNA-134 regulates lung cancer cell H69 growth and apoptosis by targeting WWOX gene and suppressing the ERK1/2 signaling pathway

Author keywords

ERK1 2; MicroRNA 134; Small cell lung cancer; WWOX

Indexed keywords

LACTATE DEHYDROGENASE; MICRORNA; MICRORNA 134; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OXIDOREDUCTASE; PROTEIN BCL 2; PROTEIN BCL XL; UNCLASSIFIED DRUG; WW DOMAIN CONTAINING OXIDOREDUCTASE; MIRN134 MICRORNA, HUMAN; RNA; TUMOR MARKER; TUMOR SUPPRESSOR PROTEIN; WWOX PROTEIN, HUMAN;

EID: 84938745657     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.07.021     Document Type: Article
Times cited : (23)

References (45)
  • 1
    • 35848945663 scopus 로고    scopus 로고
    • Skip mediastinal nodal metastases in the IIIa/N2 non-small cell lung cancer
    • N. Ilic, A. Petricevic, D. Arar, and et al. Skip mediastinal nodal metastases in the IIIa/N2 non-small cell lung cancer J. Thorac. Oncol. 2 2007 1018 1021
    • (2007) J. Thorac. Oncol. , vol.2 , pp. 1018-1021
    • Ilic, N.1    Petricevic, A.2    Arar, D.3
  • 3
    • 0030912190 scopus 로고    scopus 로고
    • Revisions in the international system for staging lung cancer
    • C.F. Mountain Revisions in the international system for staging lung cancer Chest J. 111 1997 1710 1717
    • (1997) Chest J. , vol.111 , pp. 1710-1717
    • Mountain, C.F.1
  • 4
    • 33750603100 scopus 로고    scopus 로고
    • Changing epidemiology of small-cell lung cancer in the United States over the last 30 years: analysis of the surveillance, epidemiologic, and end results database
    • R. Govindan, N. Page, D. Morgensztern, and et al. Changing epidemiology of small-cell lung cancer in the United States over the last 30 years: analysis of the surveillance, epidemiologic, and end results database J. Clin. Oncol. 24 2006 4539 4544
    • (2006) J. Clin. Oncol. , vol.24 , pp. 4539-4544
    • Govindan, R.1    Page, N.2    Morgensztern, D.3
  • 5
    • 0035872199 scopus 로고    scopus 로고
    • Akt/protein kinase B is constitutively active in non-small cell lung cancer cells and promotes cellular survival and resistance to chemotherapy and radiation
    • J. Brognard, A.S. Clark, Y. Ni, and et al. Akt/protein kinase B is constitutively active in non-small cell lung cancer cells and promotes cellular survival and resistance to chemotherapy and radiation Cancer Res. 61 2001 3986 3997
    • (2001) Cancer Res. , vol.61 , pp. 3986-3997
    • Brognard, J.1    Clark, A.S.2    Ni, Y.3
  • 6
    • 4644309196 scopus 로고    scopus 로고
    • The functions of animal microRNAs
    • V. Ambros The functions of animal microRNAs Nature 431 2004 350 355
    • (2004) Nature , vol.431 , pp. 350-355
    • Ambros, V.1
  • 7
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: target recognition and regulatory functions
    • D.P. Bartel MicroRNAs: target recognition and regulatory functions Cell 136 2009 215 233
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 8
    • 33750370444 scopus 로고    scopus 로고
    • MicroRNA signatures in human cancers
    • G.A. Calin, and C.M. Croce MicroRNA signatures in human cancers Nat. Rev. Cancer 6 2006 857 866
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 857-866
    • Calin, G.A.1    Croce, C.M.2
  • 9
    • 84867576424 scopus 로고    scopus 로고
    • miR-134 inhibits epithelial to mesenchymal transition by targeting FOXM1 in non-small cell lung cancer cells
    • J. Li, Y. Wang, J. Luo, and et al. miR-134 inhibits epithelial to mesenchymal transition by targeting FOXM1 in non-small cell lung cancer cells FEBS Lett. 586 2012 3761 3765
    • (2012) FEBS Lett. , vol.586 , pp. 3761-3765
    • Li, J.1    Wang, Y.2    Luo, J.3
  • 10
    • 77957028147 scopus 로고    scopus 로고
    • MicroRNAs as therapeutic targets for lung cancer
    • W.C. Cho MicroRNAs as therapeutic targets for lung cancer Expert Opin. Ther. Targets 14 2010 1005 1008
    • (2010) Expert Opin. Ther. Targets , vol.14 , pp. 1005-1008
    • Cho, W.C.1
  • 11
    • 84890123452 scopus 로고    scopus 로고
    • miR-134 induces oncogenicity and metastasis in head and neck carcinoma through targeting WWOX gene
    • C.J. Liu, W.G. Shen, S.Y. Peng, and et al. miR-134 induces oncogenicity and metastasis in head and neck carcinoma through targeting WWOX gene Int. J. Cancer 134 2014 811 821
    • (2014) Int. J. Cancer , vol.134 , pp. 811-821
    • Liu, C.J.1    Shen, W.G.2    Peng, S.Y.3
  • 12
    • 84925304784 scopus 로고    scopus 로고
    • Roles of the WWOX in pathogenesis and endocrine therapy of breast cancer
    • J. Li, J. Liu, Y. Ren, and et al. Roles of the WWOX in pathogenesis and endocrine therapy of breast cancer Exp. Biol. Med. 2014 10.1177/1535370214561587
    • (2014) Exp. Biol. Med.
    • Li, J.1    Liu, J.2    Ren, Y.3
  • 13
    • 17444440946 scopus 로고    scopus 로고
    • Common chromosomal fragile site FRA16D sequence: identification of the FOR gene spanning FRA16D and homozygous deletions and translocation breakpoints in cancer cells
    • K. Ried, M. Finnis, L. Hobson, and et al. Common chromosomal fragile site FRA16D sequence: identification of the FOR gene spanning FRA16D and homozygous deletions and translocation breakpoints in cancer cells Hum. Mol. Genet. 9 2000 1651 1663
    • (2000) Hum. Mol. Genet. , vol.9 , pp. 1651-1663
    • Ried, K.1    Finnis, M.2    Hobson, L.3
  • 14
    • 0034655131 scopus 로고    scopus 로고
    • WWOX, a novel WW domain-containing protein mapping to human chromosome 16q23. 3-24.1, a region frequently affected in breast cancer
    • A.K. Bednarek, K.J. Laflin, R.L. Daniel, and et al. WWOX, a novel WW domain-containing protein mapping to human chromosome 16q23. 3-24.1, a region frequently affected in breast cancer Cancer Res. 60 2000 2140 2145
    • (2000) Cancer Res. , vol.60 , pp. 2140-2145
    • Bednarek, A.K.1    Laflin, K.J.2    Daniel, R.L.3
  • 15
    • 67749116085 scopus 로고    scopus 로고
    • WWOX, the tumour suppressor gene affected in multiple cancers
    • U. Lewandowska, M. Zelazowski, K. Seta, and et al. WWOX, the tumour suppressor gene affected in multiple cancers J. Physiol. Pharmacol. 60 2009 47 56
    • (2009) J. Physiol. Pharmacol. , vol.60 , pp. 47-56
    • Lewandowska, U.1    Zelazowski, M.2    Seta, K.3
  • 16
    • 31844432243 scopus 로고    scopus 로고
    • Characterization of the tumor suppressor gene WWOX in primary human oral squamous cell carcinomas
    • F.J. Pimenta, D.A. Gomes, P.F. Perdigão, and et al. Characterization of the tumor suppressor gene WWOX in primary human oral squamous cell carcinomas Int. J. Cancer 118 2006 1154 1158
    • (2006) Int. J. Cancer , vol.118 , pp. 1154-1158
    • Pimenta, F.J.1    Gomes, D.A.2    Perdigão, P.F.3
  • 17
    • 34347371806 scopus 로고    scopus 로고
    • WWOX in biological control and tumorigenesis
    • R.I. Aqeilan, and C.M. Croce WWOX in biological control and tumorigenesis J. Cell. Physiol. 212 2007 307 310
    • (2007) J. Cell. Physiol. , vol.212 , pp. 307-310
    • Aqeilan, R.I.1    Croce, C.M.2
  • 18
    • 70350463840 scopus 로고    scopus 로고
    • WWOX: its genomics, partners, and functions
    • S. Del Mare, Z. Salah, and R.I. Aqeilan WWOX: its genomics, partners, and functions J. Cell. Biochem. 108 2009 737 745
    • (2009) J. Cell. Biochem. , vol.108 , pp. 737-745
    • Del Mare, S.1    Salah, Z.2    Aqeilan, R.I.3
  • 19
    • 77953783825 scopus 로고    scopus 로고
    • Signaling from membrane receptors to tumor suppressor WW domain-containing oxidoreductase
    • J.-Y. Chang, R.-Y. He, H.-P. Lin, and et al. Signaling from membrane receptors to tumor suppressor WW domain-containing oxidoreductase Exp. Biol. Med. 235 2010 796 804
    • (2010) Exp. Biol. Med. , vol.235 , pp. 796-804
    • Chang, J.-Y.1    He, R.-Y.2    Lin, H.-P.3
  • 20
    • 34250826625 scopus 로고    scopus 로고
    • Inactivation of the Wwox gene accelerates forestomach tumor progression in vivo
    • R.I. Aqeilan, J.P. Hagan, H.A. Aqeilan, and et al. Inactivation of the Wwox gene accelerates forestomach tumor progression in vivo Cancer Res. 67 2007 5606 5610
    • (2007) Cancer Res. , vol.67 , pp. 5606-5610
    • Aqeilan, R.I.1    Hagan, J.P.2    Aqeilan, H.A.3
  • 21
    • 84855690496 scopus 로고    scopus 로고
    • Role of the WWOX tumor suppressor gene in bone homeostasis and the pathogenesis of osteosarcoma
    • S. Del Mare, K.C. Kurek, G.S. Stein, and et al. Role of the WWOX tumor suppressor gene in bone homeostasis and the pathogenesis of osteosarcoma Am. J. Cancer Res. 1 2011 585
    • (2011) Am. J. Cancer Res. , vol.1 , pp. 585
    • Del Mare, S.1    Kurek, K.C.2    Stein, G.S.3
  • 22
    • 66349110227 scopus 로고    scopus 로고
    • WWOX gene expression abolishes ovarian cancer tumorigenicity in vivo and decreases attachment to fibronectin via integrin α3
    • C. Gourley, A.J. Paige, K.J. Taylor, and et al. WWOX gene expression abolishes ovarian cancer tumorigenicity in vivo and decreases attachment to fibronectin via integrin α3 Cancer Res. 69 2009 4835 4842
    • (2009) Cancer Res. , vol.69 , pp. 4835-4842
    • Gourley, C.1    Paige, A.J.2    Taylor, K.J.3
  • 23
    • 33845879138 scopus 로고    scopus 로고
    • WW domain-containing oxidoreductase: a candidate tumor suppressor
    • N.-S. Chang, L.-J. Hsu, Y.-S. Lin, and et al. WW domain-containing oxidoreductase: a candidate tumor suppressor Trends Mol. Med. 13 2007 12 22
    • (2007) Trends Mol. Med. , vol.13 , pp. 12-22
    • Chang, N.-S.1    Hsu, L.-J.2    Lin, Y.-S.3
  • 24
    • 12144289659 scopus 로고    scopus 로고
    • Functional association between Wwox tumor suppressor protein and p73, a p53 homolog
    • R.I. Aqeilan, Y. Pekarsky, J.J. Herrero, and et al. Functional association between Wwox tumor suppressor protein and p73, a p53 homolog Proc. Natl. Acad. Sci. U. S. A. 101 2004 4401 4406
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 4401-4406
    • Aqeilan, R.I.1    Pekarsky, Y.2    Herrero, J.J.3
  • 25
    • 84932091996 scopus 로고    scopus 로고
    • Tumor suppressor WWOX regulates glucose metabolism via HIF1α modulation
    • M. Abu-Remaileh, and R. Aqeilan Tumor suppressor WWOX regulates glucose metabolism via HIF1α modulation Cell Death Differ. 21 2014 1805 1814
    • (2014) Cell Death Differ. , vol.21 , pp. 1805-1814
    • Abu-Remaileh, M.1    Aqeilan, R.2
  • 26
    • 33847375923 scopus 로고    scopus 로고
    • WWOX expression in different histologic types and subtypes of non-small cell lung cancer
    • V. Donati, G. Fontanini, M. Dell'Omodarme, and et al. WWOX expression in different histologic types and subtypes of non-small cell lung cancer Clin. Cancer Res. 13 2007 884 891
    • (2007) Clin. Cancer Res. , vol.13 , pp. 884-891
    • Donati, V.1    Fontanini, G.2    Dell'omodarme, M.3
  • 28
    • 20144372911 scopus 로고    scopus 로고
    • Fragile genes as biomarkers: epigenetic control of WWOX and FHIT in lung, breast and bladder cancer
    • D. Iliopoulos, G. Guler, S.-Y. Han, and et al. Fragile genes as biomarkers: epigenetic control of WWOX and FHIT in lung, breast and bladder cancer Oncogene 24 2005 1625 1633
    • (2005) Oncogene , vol.24 , pp. 1625-1633
    • Iliopoulos, D.1    Guler, G.2    Han, S.-Y.3
  • 29
    • 79952836454 scopus 로고    scopus 로고
    • Multi-walled carbon nanotubes induce oxidative stress and apoptosis in human lung cancer cell line-A549
    • R.K. Srivastava, A.B. Pant, M.P. Kashyap, and et al. Multi-walled carbon nanotubes induce oxidative stress and apoptosis in human lung cancer cell line-A549 Nanotoxicology 5 2011 195 207
    • (2011) Nanotoxicology , vol.5 , pp. 195-207
    • Srivastava, R.K.1    Pant, A.B.2    Kashyap, M.P.3
  • 30
    • 0034653456 scopus 로고    scopus 로고
    • Comparison of the LDH and MTT assays for quantifying cell death: validity for neuronal apoptosis?
    • D. Lobner Comparison of the LDH and MTT assays for quantifying cell death: validity for neuronal apoptosis? J. Neurosci. Methods 96 2000 147 152
    • (2000) J. Neurosci. Methods , vol.96 , pp. 147-152
    • Lobner, D.1
  • 31
    • 79955519053 scopus 로고    scopus 로고
    • Overexpression of miR-200c induces chemoresistance in esophageal cancers mediated through activation of the Akt signaling pathway
    • R. Hamano, H. Miyata, M. Yamasaki, and et al. Overexpression of miR-200c induces chemoresistance in esophageal cancers mediated through activation of the Akt signaling pathway Clin. Cancer Res. 17 2011 3029 3038
    • (2011) Clin. Cancer Res. , vol.17 , pp. 3029-3038
    • Hamano, R.1    Miyata, H.2    Yamasaki, M.3
  • 32
    • 27344455410 scopus 로고    scopus 로고
    • WWOX gene restoration prevents lung cancer growth in vitro and in vivo
    • M. Fabbri, D. Iliopoulos, F. Trapasso, and et al. WWOX gene restoration prevents lung cancer growth in vitro and in vivo Proc. Natl. Acad. Sci. U. S. A. 102 2005 15611 15616
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , pp. 15611-15616
    • Fabbri, M.1    Iliopoulos, D.2    Trapasso, F.3
  • 33
    • 33846274591 scopus 로고    scopus 로고
    • Inhibition of breast cancer cell growth in vitro and in vivo: effect of restoration of Wwox expression
    • D. Iliopoulos, M. Fabbri, T. Druck, and et al. Inhibition of breast cancer cell growth in vitro and in vivo: effect of restoration of Wwox expression Clin. Cancer Res. 13 2007 268 274
    • (2007) Clin. Cancer Res. , vol.13 , pp. 268-274
    • Iliopoulos, D.1    Fabbri, M.2    Druck, T.3
  • 34
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method
    • K.J. Livak, and T.D. Schmittgen Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method Methods 25 2001 402 408
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 35
    • 80052000657 scopus 로고    scopus 로고
    • Tumor suppressor WWOX interacts with MEK2 and activates ERK pathway
    • S. Cho Tumor suppressor WWOX interacts with MEK2 and activates ERK pathway Bull. Korean Chem. Soc. 32 2011 2817 2819
    • (2011) Bull. Korean Chem. Soc. , vol.32 , pp. 2817-2819
    • Cho, S.1
  • 36
    • 0034997845 scopus 로고    scopus 로고
    • Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions 1
    • G. Pearson, F. Robinson, T. Beers Gibson, and et al. Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions 1 Endocr. Rev. 22 2001 153 183
    • (2001) Endocr. Rev. , vol.22 , pp. 153-183
    • Pearson, G.1    Robinson, F.2    Beers Gibson, T.3
  • 37
    • 0034098405 scopus 로고    scopus 로고
    • Signaling angiogenesis via p42/p44 MAP kinase cascade
    • J. Milanini, D.E. Richard, E. Berra, and et al. Signaling angiogenesis via p42/p44 MAP kinase cascade Ann. N. Y. Acad. Sci. 902 2000 187 200
    • (2000) Ann. N. Y. Acad. Sci. , vol.902 , pp. 187-200
    • Milanini, J.1    Richard, D.E.2    Berra, E.3
  • 38
    • 36249012382 scopus 로고    scopus 로고
    • EGF-receptor-mediated mammary epithelial cell migration is driven by sustained ERK signaling from autocrine stimulation
    • E.J. Joslin, L.K. Opresko, A. Wells, and et al. EGF-receptor-mediated mammary epithelial cell migration is driven by sustained ERK signaling from autocrine stimulation J. Cell Sci. 120 2007 3688 3699
    • (2007) J. Cell Sci. , vol.120 , pp. 3688-3699
    • Joslin, E.J.1    Opresko, L.K.2    Wells, A.3
  • 39
    • 20144373433 scopus 로고    scopus 로고
    • Reduced expression of Dicer associated with poor prognosis in lung cancer patients
    • Y. Karube, H. Tanaka, H. Osada, and et al. Reduced expression of Dicer associated with poor prognosis in lung cancer patients Cancer Sci. 96 2005 111 115
    • (2005) Cancer Sci. , vol.96 , pp. 111-115
    • Karube, Y.1    Tanaka, H.2    Osada, H.3
  • 40
    • 42749093490 scopus 로고    scopus 로고
    • MicroRNA signatures of TRAIL resistance in human non-small cell lung cancer
    • M. Garofalo, C. Quintavalle, G. Di Leva, and et al. MicroRNA signatures of TRAIL resistance in human non-small cell lung cancer Oncogene 27 2008 3845 3855
    • (2008) Oncogene , vol.27 , pp. 3845-3855
    • Garofalo, M.1    Quintavalle, C.2    Di Leva, G.3
  • 41
    • 79952603697 scopus 로고    scopus 로고
    • Prognostic implications of miR-16 expression levels in resected non-small-cell lung cancer
    • A. Navarro, T. Diaz, E. Gallardo, and et al. Prognostic implications of miR-16 expression levels in resected non-small-cell lung cancer J. Surg. Oncol. 103 2011 411 415
    • (2011) J. Surg. Oncol. , vol.103 , pp. 411-415
    • Navarro, A.1    Diaz, T.2    Gallardo, E.3
  • 42
    • 77952583481 scopus 로고    scopus 로고
    • Gene expression profiling of drug-resistant small cell lung cancer cells by combining microRNA and cDNA expression analysis
    • L. Guo, Y. Liu, Y. Bai, and et al. Gene expression profiling of drug-resistant small cell lung cancer cells by combining microRNA and cDNA expression analysis Eur. J. Cancer 46 2010 1692 1702
    • (2010) Eur. J. Cancer , vol.46 , pp. 1692-1702
    • Guo, L.1    Liu, Y.2    Bai, Y.3
  • 43
    • 84862791275 scopus 로고    scopus 로고
    • MiR-134 functions as a regulator of cell proliferation, apoptosis, and migration involving lung septation
    • X. Zhang, H. Wang, S. Zhang, and et al. MiR-134 functions as a regulator of cell proliferation, apoptosis, and migration involving lung septation In Vitro Cell. Dev. Biol. Anim. 48 2012 131 136
    • (2012) In Vitro Cell. Dev. Biol. Anim. , vol.48 , pp. 131-136
    • Zhang, X.1    Wang, H.2    Zhang, S.3
  • 44
    • 84876012922 scopus 로고    scopus 로고
    • MiR-134 regulates the proliferation and invasion of glioblastoma cells by reducing Nanog expression
    • C.S. Niu, Y. Yang, and C.-D. Cheng MiR-134 regulates the proliferation and invasion of glioblastoma cells by reducing Nanog expression Int. J. Oncol. 42 2013 1533 1540
    • (2013) Int. J. Oncol. , vol.42 , pp. 1533-1540
    • Niu, C.S.1    Yang, Y.2    Cheng, C.-D.3
  • 45
    • 0036716281 scopus 로고    scopus 로고
    • The Bcl2 family: regulators of the cellular life-or-death switch
    • S. Cory, and J.M. Adams The Bcl2 family: regulators of the cellular life-or-death switch Nat. Rev. Cancer 2 2002 647 656
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 647-656
    • Cory, S.1    Adams, J.M.2


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