Low cytochrome oxidase 4I1 links mitochondrial dysfunction to obesity and type 2 diabetes in humans and mice

International Journal of Obesity

Volumn 39, Issue 8, 2015, Pages 1254-1263

  Van Der Schueren, B ^a   Vangoitsenhoven, R ^a   Geeraert, B ^a   De Keyzer, D ^a   Hulsmans, M ^a   Lannoo, M ^a   Huber, H J ^a   Mathieu, C ^a   Holvoet, P ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; ADIPONECTIN; BIOLOGICAL MARKER; C REACTIVE PROTEIN; CYCLOOXYGENASE 10; CYTOCHROME C OXIDASE; CYTOCHROME C OXIDASE 4I1; GLUCOSE; GLUCOSE TRANSPORTER 4; GLUTATHIONE PEROXIDASE 1; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 3; INTERLEUKIN 6; LEPTIN; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; OXYGENASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; SUPEROXIDE DISMUTASE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; COX10 PROTEIN, HUMAN; COX10 PROTEIN, MOUSE; COX4I1 PROTEIN, MOUSE; MEMBRANE PROTEIN; TRANSFERASE;

ADIPOSE TISSUE; ADULT; ANIMAL TISSUE; ARTICLE; BARIATRIC SURGERY; BODY MASS; BODY WEIGHT; CALORIC RESTRICTION; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DIABETIC OBESITY; DIASTOLIC BLOOD PRESSURE; DISEASE ASSOCIATION; DISORDERS OF MITOCHONDRIAL FUNCTIONS; FEMALE; FOOD INTAKE; GENE EXPRESSION; GLUCOSE TRANSPORT; HUMAN; HUMAN TISSUE; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; INSULIN SENSITIVITY; INTRAABDOMINAL FAT; MAJOR CLINICAL STUDY; MALE; MONOCYTE; MOUSE; NEGATIVE FEEDBACK; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; OXIDATIVE STRESS; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RANDOMIZED CONTROLLED TRIAL; SINGLE BLIND PROCEDURE; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; SYSTOLIC BLOOD PRESSURE; ANIMAL; ELECTRON TRANSPORT; EXPERIMENTAL DIABETES MELLITUS; GENETIC VARIATION; GENETICS; MITOCHONDRION; MORBID OBESITY; MOUSE MUTANT; PATHOLOGY; PATHOPHYSIOLOGY; WEIGHT REDUCTION;

MUS;

ALKYL AND ARYL TRANSFERASES; ANIMALS; BARIATRIC SURGERY; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; ELECTRON TRANSPORT; ELECTRON TRANSPORT COMPLEX IV; GENETIC VARIATION; HUMANS; INSULIN RESISTANCE; MEMBRANE PROTEINS; MICE; MICE, OBESE; MITOCHONDRIA; OBESITY, MORBID; WEIGHT LOSS;

EID: 84938741423     PISSN: 03070565     EISSN: 14765497     Source Type: Journal    
DOI: 10.1038/ijo.2015.58     Document Type: Article

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