메뉴 건너뛰기




Volumn 39, Issue 8, 2015, Pages 1300-1309

Aryl hydrocarbon receptor deficiency protects mice from diet-induced adiposity and metabolic disorders through increased energy expenditure

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC HYDROCARBON RECEPTOR; FAT; INSULIN; LIPID; MITOCHONDRIAL PROTEIN; UNCOUPLING PROTEIN 1; AHR PROTEIN, MOUSE; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR;

EID: 84938741067     PISSN: 03070565     EISSN: 14765497     Source Type: Journal    
DOI: 10.1038/ijo.2015.63     Document Type: Article
Times cited : (95)

References (38)
  • 1
    • 84896690513 scopus 로고    scopus 로고
    • Prevalence of childhood and adult obesity in the United States, 2011-2012
    • Ogden CL, Carroll MD, Kit BK, Flegal KM. Prevalence of childhood and adult obesity in the United States, 2011-2012. JAMA 2014; 311: 806-814
    • (2014) JAMA , vol.311 , pp. 806-814
    • Ogden, C.L.1    Carroll, M.D.2    Kit, B.K.3    Flegal, K.M.4
  • 3
    • 0036183630 scopus 로고    scopus 로고
    • The mechanisms of action of ppars
    • Berger J, Moller DE. The mechanisms of action of PPARs. Annu Rev Med 2002; 53: 409-435
    • (2002) Annu Rev Med , vol.53 , pp. 409-435
    • Berger, J.1    Moller, D.E.2
  • 4
    • 0037453718 scopus 로고    scopus 로고
    • Peroxisome-proliferatoractivated receptor delta activates fat metabolism to prevent obesity
    • Wang YX, Lee CH, Tiep S, Yu RT, Ham J, Kang H et al. Peroxisome-proliferatoractivated receptor delta activates fat metabolism to prevent obesity. Cell 2003; 113: 159-170
    • (2003) Cell , vol.113 , pp. 159-170
    • Wang, Y.X.1    Lee, C.H.2    Tiep, S.3    Yu, R.T.4    Ham, J.5    Kang, H.6
  • 5
    • 84877798556 scopus 로고    scopus 로고
    • PXR ablation alleviates diet-induced and genetic obesity and insulin resistance in mice
    • He J, Gao J, Xu M, Ren S, Stefanovic-Racic M, O'Doherty RM et al. PXR ablation alleviates diet-induced and genetic obesity and insulin resistance in mice. Diabetes 2013; 62: 1876-1887
    • (2013) Diabetes , vol.62 , pp. 1876-1887
    • He, J.1    Gao, J.2    Xu, M.3    Ren, S.4    Stefanovic-Racic, M.5    O'Doherty, R.M.6
  • 7
    • 0030983681 scopus 로고    scopus 로고
    • Serum dioxin and diabetes mellitus in veterans of operation ranch hand
    • Henriksen GL, Ketchum NS, Michalek JE, Swaby JA. Serum dioxin and diabetes mellitus in veterans of Operation Ranch Hand. Epidemiology 1997; 8: 252-258
    • (1997) Epidemiology , vol.8 , pp. 252-258
    • Henriksen, G.L.1    Ketchum, N.S.2    Michalek, J.E.3    Swaby, J.A.4
  • 8
    • 33750863486 scopus 로고    scopus 로고
    • Molecular epidemiologic evidence for diabetogenic effects of dioxin exposure in us air force veterans of the Vietnam war
    • Fujiyoshi PT, Michalek JE, Matsumura F. Molecular epidemiologic evidence for diabetogenic effects of dioxin exposure in U.S. Air force veterans of the Vietnam war. Environ Health Perspect 2006; 114: 1677-1683
    • (2006) Environ Health Perspect , vol.114 , pp. 1677-1683
    • Fujiyoshi, P.T.1    Michalek, J.E.2    Matsumura, F.3
  • 9
    • 84881007191 scopus 로고    scopus 로고
    • Diabetes, metabolic syndrome, and obesity in relation to serum dioxin concentrations: The seveso women's health study
    • Warner M, Mocarelli P, Brambilla P, Wesselink A, Samuels S, Signorini S et al. Diabetes, metabolic syndrome, and obesity in relation to serum dioxin concentrations: The Seveso Women's Health Study. Environ Health Perspect 2013; 121: 906-911
    • (2013) Environ Health Perspect , vol.121 , pp. 906-911
    • Warner, M.1    Mocarelli, P.2    Brambilla, P.3    Wesselink, A.4    Samuels, S.5    Signorini, S.6
  • 10
    • 84879557446 scopus 로고    scopus 로고
    • Evaluation of the association between persistent organic pollutants (pops) and diabetes in epidemiological studies: A national toxicology program workshop review
    • Taylor KW, Novak RF, Anderson HA, Birnbaum LS, Blystone C, Devito M et al. Evaluation of the association between persistent organic pollutants (POPs) and diabetes in epidemiological studies: a national toxicology program workshop review. Environ Health Perspect 2013; 121: 774-783
    • (2013) Environ Health Perspect , vol.121 , pp. 774-783
    • Taylor, K.W.1    Novak, R.F.2    Anderson, H.A.3    Birnbaum, L.S.4    Blystone, C.5    Devito, M.6
  • 11
    • 84863489454 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and insulin resistance: The contribution of dioxin-like substances
    • Lee HK. Mitochondrial dysfunction and insulin resistance: the contribution of dioxin-like substances. Diabetes Metab J 2011; 35: 207-215
    • (2011) Diabetes Metab J , vol.35 , pp. 207-215
    • Lee, H.K.1
  • 12
    • 77954070319 scopus 로고    scopus 로고
    • 2, 3, 7, 8-tetrachlorodibenzop- dioxin impairs an insulin signaling pathway through the induction of tumor necrosis factor-alpha in adipocytes
    • Nishiumi S, Yoshida M, Azuma T, Yoshida K, Ashida H. 2, 3, 7, 8-tetrachlorodibenzop- dioxin impairs an insulin signaling pathway through the induction of tumor necrosis factor-alpha in adipocytes. Toxicol Sci 2010; 115: 482-491
    • (2010) Toxicol Sci , vol.115 , pp. 482-491
    • Nishiumi, S.1    Yoshida, M.2    Azuma, T.3    Yoshida, K.4    Ashida, H.5
  • 13
    • 84878971275 scopus 로고    scopus 로고
    • Activation of the aryl hydrocarbon receptor sensitizes mice to nonalcoholic steatohepatitis by deactivating mitochondrial sirtuin deacetylase Sirt3
    • He J, Hu B, Shi X, Weidert ER, Lu P, Xu M et al. Activation of the aryl hydrocarbon receptor sensitizes mice to nonalcoholic steatohepatitis by deactivating mitochondrial sirtuin deacetylase Sirt3. Mol Cell Biol 2013; 33: 2047-2055
    • (2013) Mol Cell Biol , vol.33 , pp. 2047-2055
    • He, J.1    Hu, B.2    Shi, X.3    Weidert, E.R.4    Lu, P.5    Xu, M.6
  • 14
    • 46749092580 scopus 로고    scopus 로고
    • Polychlorinated biphenyl-77 induces adipocyte differentiation and proinflammatory adipokines and promotes obesity and atherosclerosis
    • Arsenescu V, Arsenescu RI, King V, Swanson H, Cassis LA. Polychlorinated biphenyl-77 induces adipocyte differentiation and proinflammatory adipokines and promotes obesity and atherosclerosis. Environ Health Perspect 2008; 116: 761-768
    • (2008) Environ Health Perspect , vol.116 , pp. 761-768
    • Arsenescu, V.1    Arsenescu, R.I.2    King, V.3    Swanson, H.4    Cassis, L.A.5
  • 16
    • 0030015421 scopus 로고    scopus 로고
    • Characterization of a murine ahr null allele: Involvement of the ah receptor in hepatic growth and development
    • Schmidt JV, Su GH, Reddy JK, Simon MC, Bradfield CA. Characterization of a murine Ahr null allele: involvement of the Ah receptor in hepatic growth and development. Proc Natl Acad Sci USA 1996; 93: 6731-6736
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 6731-6736
    • Schmidt, J.V.1    Su, G.H.2    Reddy, J.K.3    Simon, M.C.4    Bradfield, C.A.5
  • 18
    • 77951918926 scopus 로고    scopus 로고
    • Macrophages, inflammation, and insulin resistance
    • Olefsky JM, Glass CK. Macrophages, inflammation, and insulin resistance. Annu Rev Physiol 2010; 72: 219-246
    • (2010) Annu Rev Physiol , vol.72 , pp. 219-246
    • Olefsky, J.M.1    Glass, C.K.2
  • 20
    • 84879044408 scopus 로고    scopus 로고
    • What about non-alcoholic fatty liver disease as a new criterion to define metabolic syndrome
    • Tarantino G, Finelli C. What about non-alcoholic fatty liver disease as a new criterion to define metabolic syndrome? World J Gastroenterol 2013; 19: 3375-3384
    • (2013) World J Gastroenterol , vol.19 , pp. 3375-3384
    • Tarantino, G.1    Finelli, C.2
  • 22
    • 77955488532 scopus 로고    scopus 로고
    • A novel role for the dioxin receptor in fatty acid metabolism and hepatic steatosis
    • Lee JH, Wada T, Febbraio M, He J, Matsubara T, Lee MJ et al. A novel role for the dioxin receptor in fatty acid metabolism and hepatic steatosis. Gastroenterology 2010; 139: 653-663
    • (2010) Gastroenterology , vol.139 , pp. 653-663
    • Lee, J.H.1    Wada, T.2    Febbraio, M.3    He, J.4    Matsubara, T.5    Lee, M.J.6
  • 23
    • 82755192186 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor deficiency enhances insulin sensitivity and reduces PPAR-alpha pathway activity in mice
    • Wang C, Xu CX, Krager SL, Bottum KM, Liao DF, Tischkau SA. Aryl hydrocarbon receptor deficiency enhances insulin sensitivity and reduces PPAR-alpha pathway activity in mice. Environ Health Perspect 2011; 119: 1739-1744
    • (2011) Environ Health Perspect , vol.119 , pp. 1739-1744
    • Wang, C.1    Xu, C.X.2    Krager, S.L.3    Bottum, K.M.4    Liao, D.F.5    Tischkau, S.A.6
  • 24
    • 68349150756 scopus 로고    scopus 로고
    • CD8+ effector t cells contribute to macrophage recruitment and adipose tissue inflammation in obesity
    • Nishimura S, Manabe I, Nagasaki M, Eto K, Yamashita H, Ohsugi M et al. CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity. Nat Med 2009; 15: 914-920
    • (2009) Nat Med , vol.15 , pp. 914-920
    • Nishimura, S.1    Manabe, I.2    Nagasaki, M.3    Eto, K.4    Yamashita, H.5    Ohsugi, M.6
  • 25
    • 68349137821 scopus 로고    scopus 로고
    • Normalization of obesity-associated insulin resistance through immunotherapy
    • Winer S, Chan Y, Paltser G, Truong D, Tsui H, Bahrami J et al. Normalization of obesity-associated insulin resistance through immunotherapy. Nat Med 2009; 15: 921-929
    • (2009) Nat Med , vol.15 , pp. 921-929
    • Winer, S.1    Chan, Y.2    Paltser, G.3    Truong, D.4    Tsui, H.5    Bahrami, J.6
  • 26
    • 68349160704 scopus 로고    scopus 로고
    • Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice
    • Liu J, Divoux A, Sun J, Zhang J, Clement K, Glickman JN et al. Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice. Nat Med 2009; 15: 940-945
    • (2009) Nat Med , vol.15 , pp. 940-945
    • Liu, J.1    Divoux, A.2    Sun, J.3    Zhang, J.4    Clement, K.5    Glickman, J.N.6
  • 27
    • 84868671526 scopus 로고    scopus 로고
    • Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase
    • Talukdar S, Oh da Y, Bandyopadhyay G, Li D, Xu J, McNelis J et al. Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase. Nat Med 2012; 18: 1407-1412
    • (2012) Nat Med , vol.18 , pp. 1407-1412
    • Talukdar, S.1    Oh Da, Y.2    Bandyopadhyay, G.3    Li, D.4    Xu, J.5    McNelis, J.6
  • 28
    • 85027938385 scopus 로고    scopus 로고
    • B cells promote insulin resistance through modulation of t cells and production of pathogenic igg antibodies
    • Winer DA, Winer S, Shen L, Wadia PP, Yantha J, Paltser G et al. B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies. Nat Med 2011; 17: 610-617
    • (2011) Nat Med , vol.17 , pp. 610-617
    • Winer, D.A.1    Winer, S.2    Shen, L.3    Wadia, P.P.4    Yantha, J.5    Paltser, G.6
  • 29
    • 84879181079 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor controls murine mast cell homeostasis
    • Zhou Y, Tung HY, Tsai YM, Hsu SC, Chang HW, Kawasaki H et al. Aryl hydrocarbon receptor controls murine mast cell homeostasis. Blood 2013; 121: 3195-3204
    • (2013) Blood , vol.121 , pp. 3195-3204
    • Zhou, Y.1    Tung, H.Y.2    Tsai, Y.M.3    Hsu, S.C.4    Chang, H.W.5    Kawasaki, H.6
  • 30
    • 0842263981 scopus 로고    scopus 로고
    • The biology of peroxisome proliferator-activated receptors: Relationship with lipid metabolism and insulin sensitivity
    • Ferre P. The biology of peroxisome proliferator-activated receptors: relationship with lipid metabolism and insulin sensitivity. Diabetes 2004; 53: S43-S50
    • (2004) Diabetes , vol.53 , pp. S43-S50
    • Ferre, P.1
  • 31
    • 0035937174 scopus 로고    scopus 로고
    • Liporegulation in diet-induced obesity the antisteatotic role of hyperleptinemia
    • Lee Y, Wang MY, Kakuma T, Wang ZW, Babcock E, McCorkle K et al. Liporegulation in diet-induced obesity. The antisteatotic role of hyperleptinemia. J Biol Chem 2001; 276: 5629-5635
    • (2001) J Biol Chem , vol.276 , pp. 5629-5635
    • Lee, Y.1    Wang, M.Y.2    Kakuma, T.3    Wang, Z.W.4    Babcock, E.5    McCorkle, K.6
  • 32
    • 22544480378 scopus 로고    scopus 로고
    • New hepatic fat activates PPARalpha to maintain glucose, lipid, and cholesterol homeostasis
    • Chakravarthy MV, Pan Z, Zhu Y, Tordjman K, Schneider JG, Coleman T et al. 'New' hepatic fat activates PPARalpha to maintain glucose, lipid, and cholesterol homeostasis. Cell Metab 2005; 1: 309-322
    • (2005) Cell Metab , vol.1 , pp. 309-322
    • Chakravarthy, M.V.1    Pan, Z.2    Zhu, Y.3    Tordjman, K.4    Schneider, J.G.5    Coleman, T.6
  • 33
    • 77950245008 scopus 로고    scopus 로고
    • Transcriptional control of brown fat development
    • Kajimura S, Seale P, Spiegelman BM. Transcriptional control of brown fat development. Cell Metab 2010; 11: 257-262
    • (2010) Cell Metab , vol.11 , pp. 257-262
    • Kajimura, S.1    Seale, P.2    Spiegelman, B.M.3
  • 34
    • 84894132767 scopus 로고    scopus 로고
    • A new era in brown adipose tissue biology: Molecular control of brown fat development and energy homeostasis
    • Kajimura S, Saito M. A new era in brown adipose tissue biology: molecular control of brown fat development and energy homeostasis. Annu Rev Physiol 2014; 76: 225-249
    • (2014) Annu Rev Physiol , vol.76 , pp. 225-249
    • Kajimura, S.1    Saito, M.2
  • 35
    • 33846572931 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor is activated by modified low-density lipoprotein
    • McMillan BJ, Bradfield CA. The aryl hydrocarbon receptor is activated by modified low-density lipoprotein. Proc Natl Acad Sci USA 2007; 104: 1412-1417
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 1412-1417
    • McMillan, B.J.1    Bradfield, C.A.2
  • 36
    • 84918781195 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor meets immunology: Friend or foe a little of both
    • Julliard W, Fechner JH, Mezrich JD. The aryl hydrocarbon receptor meets immunology: friend or foe? A little of both. Front Immunol 2014; 5: 458
    • (2014) Front Immunol , vol.5 , pp. 458
    • Julliard, W.1    Fechner, J.H.2    Mezrich, J.D.3
  • 37
    • 84922481111 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor ligands in cancer: Friend and foe
    • Murray IA, Patterson AD, Perdew GH. Aryl hydrocarbon receptor ligands in cancer: friend and foe. Nat Rev Cancer 2014; 14: 801-814
    • (2014) Nat Rev Cancer , vol.14 , pp. 801-814
    • Murray, I.A.1    Patterson, A.D.2    Perdew, G.H.3
  • 38
    • 84903744439 scopus 로고    scopus 로고
    • Interplay between dioxin-mediated signaling and circadian clock: A possible determinant in metabolic homeostasis
    • Wang C, Zhang ZM, Xu CX, Tischkau SA. Interplay between Dioxin-mediated signaling and circadian clock: a possible determinant in metabolic homeostasis. Int J Mol Sci 2014; 15: 11700-11712
    • (2014) J Mol Sci , vol.15 , pp. 11700-11712
    • Wang, C.1    Zhang, Z.M.2    Xu, C.X.3    Tischkau, S.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.