Increased mesolimbic cue-reactivity in carriers of the mu-opioid-receptor gene OPRM1 A118G polymorphism predicts drinking outcome: A functional imaging study in alcohol dependent subjects

European Neuropsychopharmacology

Volumn 25, Issue 8, 2015, Pages 1128-1135

  Bach, Patrick ^a   Vollstardt Klein, Sabine ^a   Kirsch, Martina ^a   Hoffmann, Sabine ^a   Jorde, Anne ^a   Frank, Josef ^a   Charlet, Katrin ^b   Beck, Anne ^b   Heinz, Andreas ^b   Walter, Henrik ^b   Sommer, Wolfgang H ^a   Spanagel, Rainer ^a   Rietschel, Marcella ^a   Kiefer, Falk ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Alcoholism; Endogenous opioids; FMRI; OPRM1; Relapse; Single nucleotide polymorphism

Indexed keywords

ALANINE; ALCOHOL; GLYCINE; MU OPIATE RECEPTOR; OPRM1 PROTEIN; UNCLASSIFIED DRUG; OPRM1 PROTEIN, HUMAN;

ADULT; AGED; ALCOHOL ABSTINENCE; ALCOHOLISM; ALLELE; AMINO ACID SUBSTITUTION; ARTICLE; ASSOCIATION; BRAIN REGION; CONTROLLED STUDY; CORPUS STRIATUM; DETOXIFICATION; DRINKING BEHAVIOR; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; FUNCTIONAL NEUROIMAGING; GENE EXPRESSION; GENE FREQUENCY; GENOTYPE; HETEROZYGOTE; HUMAN; INSULA; LIMBIC CORTEX; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; NERVE POTENTIAL; NEUROFEEDBACK; PRIORITY JOURNAL; REINFORCEMENT; RELAPSE; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; WITHDRAWAL SYNDROME; ADOLESCENT; BRAIN; BRAIN MAPPING; FOLLOW UP; GENETICS; GENOTYPING TECHNIQUE; NEUROPSYCHOLOGICAL TEST; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; SURVIVAL ANALYSIS; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; ALCOHOL ABSTINENCE; ALCOHOL-RELATED DISORDERS; BRAIN; BRAIN MAPPING; CUES; FEMALE; FOLLOW-UP STUDIES; GENOTYPING TECHNIQUES; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, OPIOID, MU; SURVIVAL ANALYSIS; YOUNG ADULT;

EID: 84938740506     PISSN: 0924977X     EISSN: 18737862     Source Type: Journal    
DOI: 10.1016/j.euroneuro.2015.04.013     Document Type: Article

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