The novel inhaled glucocorticoid receptor agonist GW870086X protects against adenosine-induced bronchoconstriction in asthma

Journal of Allergy and Clinical Immunology

Volumn 136, Issue 2, 2015, Pages 501-502.e6

  Leaker, Brian R ^a   O'Connor, Brian ^a   Singh, Dave ^b   Barnes, Peter J ^c  

^a RESPIRATORY CLINICAL TRIALS LTD   (United Kingdom)

^b MANCHESTER UNIVERSITY NHS FOUNDATION TRUST   (United Kingdom)

^c NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE PHOSPHATE; FLUTICASONE PROPIONATE; GW 870086; HYDROCORTISONE; NITRIC OXIDE; OSTEOCALCIN; PLACEBO; ANTIASTHMATIC AGENT; GLUCOCORTICOID RECEPTOR; STEROID;

ADENOSINE INDUCED BRONCHOCONSTRICTION; ANTIINFLAMMATORY ACTIVITY; ASTHMA; CLINICAL ARTICLE; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG ABSORPTION; DRUG ELIMINATION; DRUG POTENCY; DRY POWDER INHALER; EXPERIMENTAL BRONCHOCONSTRICTION; FORCED EXPIRATORY VOLUME; HUMAN; HYDROCORTISONE URINE LEVEL; LETTER; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RESPIRATORY TRACT ALLERGY; TRANSACTIVATION ASSAY; ADOLESCENT; ADULT; AGONISTS; ANTAGONISTS AND INHIBITORS; BLOOD; BRONCHOCONSTRICTION; DRUG EFFECTS; GENE EXPRESSION; GENETICS; IMMUNOLOGY; INHALATION TEST; INHALATIONAL DRUG ADMINISTRATION; MALE; MIDDLE AGED; PATHOLOGY; RANDOMIZED CONTROLLED TRIAL; URINE;

ADENOSINE MONOPHOSPHATE; ADMINISTRATION, INHALATION; ADOLESCENT; ADULT; ANTI-ASTHMATIC AGENTS; ASTHMA; BRONCHIAL PROVOCATION TESTS; BRONCHOCONSTRICTION; DOUBLE-BLIND METHOD; GENE EXPRESSION; HUMANS; HYDROCORTISONE; MALE; MIDDLE AGED; OSTEOCALCIN; RECEPTORS, GLUCOCORTICOID; STEROIDS;

EID: 84938739930     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2015.01.034     Document Type: Article

References (13)

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