Culture medium from TNF-α-stimulated mesenchymal stem cells attenuates allergic conjunctivitis through multiple antiallergic mechanisms

Journal of Allergy and Clinical Immunology

Volumn 136, Issue 2, 2015, Pages 423-432.e8

  Su, Wenru ^a,b   Wan, Qian ^a   Huang, Jingwen ^a   Han, Longhui ^a   Chen, Xiaoqing ^a,c   Chen, Guihua ^b   Olsen, Nancy ^c   Zheng, Song Guo ^b,c   Liang, Dan ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b THE THIRD AFFILIATED HOSPITAL OF SUN YAT SEN UNIVERSITY   (China)

^c PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

allergic conjunctivitis; Allergy; B cells; histamine; mast cells; mesenchymal stem cells; stems cells

Indexed keywords

CYCLOOXYGENASE 2; HISTAMINE; IMMUNOGLOBULIN E; INTERLEUKIN 4; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; CULTURE MEDIUM; PTGS2 PROTEIN, MOUSE;

ALLERGIC CONJUNCTIVITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; BONE MARROW DERIVED MAST CELL; BONE MARROW DERIVED MESENCHYMAL STEM CELL; CONTROLLED STUDY; CULTURE MEDIUM; CYTOKINE PRODUCTION; ENDOTHELIUM CELL; EXPERIMENTAL ALLERGIC CONJUNCTIVITIS; HISTAMINE RELEASE; IN VITRO STUDY; INFLAMMATORY CELL; MESENCHYMAL STEM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAGWEED POLLEN; SPLEEN CELL; VASCULAR ENDOTHELIUM; ANIMAL; BAGG ALBINO MOUSE; BONE MARROW CELL; CAPILLARY PERMEABILITY; CELL DIFFERENTIATION; CHEMICALLY INDUCED; CHEMISTRY; CONJUNCTIVA; CONJUNCTIVITIS, ALLERGIC; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; MESENCHYMAL STROMA CELL; METABOLISM; PATHOLOGY; PHARMACOLOGY; POLLEN; PRIMARY CELL CULTURE; RAGWEED; SIGNAL TRANSDUCTION;

AMBROSIA; ANIMALS; B-LYMPHOCYTES; BONE MARROW CELLS; CAPILLARY PERMEABILITY; CELL DIFFERENTIATION; CONJUNCTIVA; CONJUNCTIVITIS, ALLERGIC; CULTURE MEDIA, CONDITIONED; CYCLOOXYGENASE 2; GENE EXPRESSION REGULATION; HISTAMINE; IMMUNOGLOBULIN E; INTERLEUKIN-4; MESENCHYMAL STROMAL CELLS; MICE; MICE, INBRED BALB C; POLLEN; PRIMARY CELL CULTURE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84938739715     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2014.12.1926     Document Type: Article

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