Encapsulation of Mentha Oil in Chitosan Polymer Matrix Alleviates Skin Irritation

AAPS PharmSciTech

Volumn 17, Issue 2, 2016, Pages 482-492

  Mishra, Nidhi ^a   Rai, Vineet Kumar ^a   Yadav, Kuldeep Singh ^a   Sinha, Priyam ^a   Kanaujia, Archana ^a   Chanda, Debabrata ^a   Jakhmola, Apurva ^a   Saikia, Dharmendra ^a   Yadav, Narayan Prasad ^a  

^a CSIR CENTRAL INSTITUTE OF MEDICINAL AND AROMATIC PLANTS   (India)

Author keywords

anti fungal; Candida; essential oil; microspheres; primary irritation index

Indexed keywords

ANTIFUNGAL AGENT; CHITOSAN; ESSENTIAL OIL; MACROGOL 400; MACROGOL 4000; MENTHA SPICATA L VAR VIRIDIS OIL; MICROSPHERE; UNCLASSIFIED DRUG; DELAYED RELEASE FORMULATION; OINTMENT; POLYMER; VEGETABLE OIL;

ADULT; ANIMAL EXPERIMENT; ARTICLE; COACERVATION; CONTROLLED STUDY; CROSS LINKING; DIFFERENTIAL SCANNING CALORIMETRY; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG RETENTION; FEMALE; GROWTH INHIBITION; IN VITRO STUDY; MALE; MICROENCAPSULATION; NONHUMAN; OINTMENT; PRIORITY JOURNAL; RESPONSE SURFACE METHOD; SCANNING ELECTRON MICROSCOPY; SKIN IRRITATION; ADMINISTRATION AND DOSAGE; ANIMAL; CHEMISTRY; DELAYED RELEASE FORMULATION; DRUG EFFECTS; DRUG FORMULATION; MEDICINAL CHEMISTRY; MENTHA; MICROBIOLOGY; PARTICLE SIZE; PROCEDURES; RABBIT; SKIN; TOPICAL DRUG ADMINISTRATION;

ADMINISTRATION, TOPICAL; ANIMALS; CALORIMETRY, DIFFERENTIAL SCANNING; CHEMISTRY, PHARMACEUTICAL; CHITOSAN; DELAYED-ACTION PREPARATIONS; DRUG COMPOUNDING; FEMALE; MALE; MENTHA; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; OINTMENTS; PARTICLE SIZE; PLANT OILS; POLYMERS; RABBITS; SKIN;

EID: 84938723383     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/s12249-015-0378-x     Document Type: Article

References (31)

1. Cevher E, Acma A, Sinani G, Aksu B, Zloh M, Mulazimoglu L. Bioadhesive tablets containing cyclodextrin complex of itraconazole for the treatment of vaginal candidiasis. Int J Biol Macromol. 2014;69C:124–36.
2. Simonetti G, Santamaria AR, D’Auria FD, Mulinacci N, Innocenti M, Cecchini F, et al. Evaluation of anti-candida activity of Vitis vinifera L. seed extracts obtained from wine and table cultivars. Biomed Res Int. 2014;2014, Article ID 127021, 11 pages.
3. Dhawan S, Pal A, Ancha R, Bawankule D, Yadav N, Darokar M, et al. Efficacy of CIM 1166, a combination of compounds derived from Mentha spp. in alleviating experimental vulvovaginal candidiasis in mice. World J Microbiol Biotechnol. 2009;25(1):161–3.
4. Khanuja SPS, Kumar S, Shasany AK, Dhawan S, Darokar MP, Tripathy AK, et al. Mint plant Mentha spicata L. var. viridis christened as ‘Ganga’. US Patents no. US2005/0044600 P1, 2006.
5. Hsieh WC, Chang CP, Gao YL. Controlled release properties of chitosan encapsulated volatile citronella oil microcapsules by thermal treatments. Colloid Surface B. 2006;53(2):209–14.
6. Beirão da Costa S, Duarte C, Bourbon AI, Pinheiro AC, Serra AT, Moldão Martins M, et al. Effect of the matrix system in the delivery and in vitro bioactivity of microencapsulated oregano essential oil. J Food Eng. 2012;110(2):190–9.
7. Kumar MN, Muzzarelli RA, Muzzarelli C, Sashiwa H, Domb AJ. Chitosan chemistry and pharmaceutical perspectives. Chem Rev. 2004;104(12):6017–84.
8. Dai T, Tanaka M, Huang YY, Hamblin MR. Chitosan preparations for wounds and burns: antimicrobial and wound-healing effects. Expert Rev Anti-Infect Ther. 2011;9(7):857–79.
9. Ridolfi DM, Marcato PD, Justo GZ, Cordi L, Machado D, Duran N. Chitosan-solid lipid nanoparticles as carriers for topical delivery of tretinoin. Colloid Surface B. 2012;93:36–40.
10. Muzzarelli RAA. Nanochitins and nanochitosans, paving the way to eco-friendly and energy-saving exploitation of marine resources. In: Matyjaszewski K, Möller M, editors. Polymer Science: A Comprehensive Reference. Amsterdam: Elsevier; 2012. p. 153–64.
11. Rinaudo M. Physical properties of chitosan and derivatives in sol and gel states. In: Chitosan-based systems for biopharmaceuticals. Wiley; 2012. p. 23–43.
12. Averina E, Allémann E. Encapsulation of alimentary bioactive oils of the Baikal Lake area into pH-sensitive micro- and nanoparticles. LWT Food Sci Technol. 2013;53(1):271–7.
13. Solomon B, Sahle FF, Gebre-Mariam T, Asres K, Neubert RH. Microencapsulation of citronella oil for mosquito-repellent application: formulation and in vitro permeation studies. Eur J Pharm Biopharm. 2012;80(1):61–6.
14. Maji TK, Baruah I, Dube S, Hussain MR. Microencapsulation of Zanthoxylum limonella oil (ZLO) in glutaraldehyde crosslinked gelatin for mosquito repellent application. Bioresour Technol. 2007;98(4):840–4.
15. Chung SK, Seo JY, Lim JH, Park HH, Yea MJ, Park HJ. Microencapsulation of essential oil for insect repellent in food packaging system. J Food Sci. 2013;78(5):E709–14.
16. Songkro S, Hayook N, Jaisawang J, Maneenuan D, Chuchome T, Kaewnopparat N. Investigation of inclusion complexes of citronella oil, citronellal and citronellol with β-cyclodextrin for mosquito repellent. J Incl Phenom Macrocycl Chem. 2012;72(3-4):339–55.
17. Bagheri KS, Mirzadeh H, Etrati-Khosroshahi M, Shokrgozar MA. Particle size modeling and morphology study of chitosan/gelatin/nanohydroxyapatite nanocomposite microspheres for bone tissue engineering. J Biomed Mater Res A. 2013;101(6):1758–67.
18. Rai VK, Yadav NP, Sinha P, Mishra N, Luqman S, Dwivedi H, et al. Development of cellulosic polymer based gel of novel ternary mixture of miconazole nitrate for buccal delivery. Carbohydr Polym. 2014;103:126–33.
19. Yenilmez E, Başaran E, Yazan Y. Release characteristics of vitamin E incorporated chitosan microspheres and in vitro–in vivo evaluation for topical application. Carbohydr Polym. 2011;84(2):807–11.
20. Bai C, Peng H, Xiong H, Liu Y, Zhao L, Xiao X. Carboxymethylchitosan-coated proliposomes containing coix seed oil: characterisation, stability and in vitro release evaluation. Food Chem. 2011;129(4):1695–702.
21. Arya P, Pathak K. Assessing the viability of microsponges as gastro retentive drug delivery system of curcumin: optimization and pharmacokinetics. Int J Pharm. 2014;460(1–2):1–12.
22. Carović-Stanko K, Orlić S, Politeo O, Strikić F, Kolak I, Milos M, et al. Composition and antibacterial activities of essential oils of seven Ocimum taxa. Food Chem. 2010;119(1):196–201.
23. Zhang H, Cui Y, Zhu S, Feng F, Zheng X. Characterization and antimicrobial activity of a pharmaceutical microemulsion. Int J Pharm. 2010;395(1-2):154–60.
24. OECD, Test No. 404: Acute dermal irritation/corrosion. OECD guidelines for the testing of chemicals, section 4, OECD Publishing, Paris (2002).
25. Kojic Z, Stojanovic D, Popadic S, Jokanovic M, Janackovic D. The irritative property of alpha-tricalcium phosphate to the rabbit skin. Gen Physiol Biophys. 2009;28 Spec No:168-73.
26. Yadav NP, Meher JG, Pandey N, Luqman S, Yadav KS, Chanda D. Enrichment, development, and assessment of Indian basil oil based antiseptic cream formulation utilizing hydrophilic-lipophilic balance approach. Biomed Res Int. 2013;2013, Article ID 410686, 9 pages.
27. Sarkar S, Gupta S, Variyar PS, Sharma A, Singhal RS. Hydrophobic derivatives of guar gum hydrolyzate and gum arabic as matrices for microencapsulation of mint oil. Carbohydr Polym. 2013;95(1):177–82.
28. Mokhtari-Hosseini ZB, Vasheghani-Farahani E, Heidarzadeh-Vazifekhoran A, Shojaosadati SA, Karimzadeh R, Khosravi Darani K. Statistical media optimization for growth and PHB production from methanol by a methylotrophic bacterium. Bioresour Technol. 2009;100(8):2436–43.
29. Muzzarelli RAA. Biomedical exploitation of chitin and chitosan via mechano-chemical disassembly, electrospinning, dissolution in imidazolium ionic liquids, and supercritical drying. Mar Drugs. 2011;9(9):1510–33.
30. Shojaee-Aliabadi S, Hosseini H, Mohammadifar MA, Mohammadi A, Ghasemlou M, Hosseini SM, et al. Characterization of kappa-carrageenan films incorporated plant essential oils with improved antimicrobial activity. Carbohydr Polym. 2014;101:582–91.
31. Teshome K, Gebre-Mariam T, Asres K, Perry F, Engidawork E. Toxicity studies on dermal application of plant extract of Plumbago zeylanica used in Ethiopian traditional medicine. J Ethnopharmacol. 2008;117(2):236–48.