-
1
-
-
84890503612
-
The concise guide to pharmacology 2013/14: G protein-coupled receptors
-
Alexander SP, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Spedding M, et al. (2013). The concise guide to pharmacology 2013/14: G protein-coupled receptors. Br J Pharmacol 170: 1459-1581.
-
(2013)
Br J Pharmacol
, vol.170
, pp. 1459-1581
-
-
Alexander, S.P.1
Benson, H.E.2
Faccenda, E.3
Pawson, A.J.4
Sharman, J.L.5
Spedding, M.6
-
3
-
-
0027198566
-
Plasma from patients with the pruritus of cholestasis induces opioid receptor-mediated scratching in monkeys
-
Bergasa NV, Thomas DA, Vergalla J, Turner ML, Jones EA, (1993). Plasma from patients with the pruritus of cholestasis induces opioid receptor-mediated scratching in monkeys. Life Sci 53: 1253-1257.
-
(1993)
Life Sci
, vol.53
, pp. 1253-1257
-
-
Bergasa, N.V.1
Thomas, D.A.2
Vergalla, J.3
Turner, M.L.4
Jones, E.A.5
-
4
-
-
84938682173
-
Peripheral opioids
-
chapter 18. Carstens E. Akiyama T. (eds). CRC Press: Boca Raton, FL
-
Bigliardi PL, Bigliardi-Qi M, (2014). Peripheral opioids, chapter 18. In:, Carstens E, Akiyama T, (eds). Itch Mechanisms and Treatment. CRC Press: Boca Raton, FL, pp. 1-12.
-
(2014)
Itch Mechanisms and Treatment
, pp. 1-12
-
-
Bigliardi, P.L.1
Bigliardi-Qi, M.2
-
5
-
-
65249154034
-
Opioids and the skin - Where do we stand?
-
Bigliardi PL, Tobin DJ, Gaveriaux-Ruff C, Bigliardi-Qi M, (2009). Opioids and the skin-where do we stand? Exp Dermatol 18: 424-430.
-
(2009)
Exp Dermatol
, vol.18
, pp. 424-430
-
-
Bigliardi, P.L.1
Tobin, D.J.2
Gaveriaux-Ruff, C.3
Bigliardi-Qi, M.4
-
6
-
-
84893045073
-
Antinociceptive effects of novel melatonin receptor agonists in mouse models of abdominal pain
-
Chen C, Fichna J, Laudon M, Storr M, (2014). Antinociceptive effects of novel melatonin receptor agonists in mouse models of abdominal pain. World J Gastroenterol 20: 1298-1304.
-
(2014)
World J Gastroenterol
, vol.20
, pp. 1298-1304
-
-
Chen, C.1
Fichna, J.2
Laudon, M.3
Storr, M.4
-
7
-
-
32644464871
-
Butorphanol for treatment of intractable pruritus
-
Dawn AG, Yosipovitch G, (2006). Butorphanol for treatment of intractable pruritus. J Am Acad Dermatol 54: 527-531.
-
(2006)
J Am Acad Dermatol
, vol.54
, pp. 527-531
-
-
Dawn, A.G.1
Yosipovitch, G.2
-
8
-
-
72449132032
-
Selective natural kappa opioid and cannabinoid receptor agonists with a potential role in the treatment of gastrointestinal dysfunction
-
Fichna J, Schicho R, Janecka A, Zjawiony JK, Storr M, (2009a). Selective natural kappa opioid and cannabinoid receptor agonists with a potential role in the treatment of gastrointestinal dysfunction. Drug News Perspect 22: 383-392.
-
(2009)
Drug News Perspect
, vol.22
, pp. 383-392
-
-
Fichna, J.1
Schicho, R.2
Janecka, A.3
Zjawiony, J.K.4
Storr, M.5
-
9
-
-
72449196776
-
Salvinorin A inhibits colonic transit and neurogenic ion transport in mice by activating kappa-opioid and cannabinoid receptors
-
Fichna J, Schicho R, Andrews CN, Bashashati M, Klompus M, McKay DM, et al. (2009b). Salvinorin A inhibits colonic transit and neurogenic ion transport in mice by activating kappa-opioid and cannabinoid receptors. Neurogastroenterol Motil 21: 1326-e128.
-
(2009)
Neurogastroenterol Motil
, vol.21
, pp. 1326-e128
-
-
Fichna, J.1
Schicho, R.2
Andrews, C.N.3
Bashashati, M.4
Klompus, M.5
McKay, D.M.6
-
10
-
-
84861334183
-
Salvinorin A has antiinflammatory and antinociceptive effects in experimental models of colitis in mice mediated by KOR and CB1 receptors
-
Fichna J, Dicay M, Lewellyn K, Janecka A, Zjawiony JK, MacNaughton WK, et al. (2012). Salvinorin A has antiinflammatory and antinociceptive effects in experimental models of colitis in mice mediated by KOR and CB1 receptors. Inflamm Bowel Dis 18: 1137-1145.
-
(2012)
Inflamm Bowel Dis
, vol.18
, pp. 1137-1145
-
-
Fichna, J.1
Dicay, M.2
Lewellyn, K.3
Janecka, A.4
Zjawiony, J.K.5
MacNaughton, W.K.6
-
11
-
-
5044236418
-
Kappa opioid agonists suppress chloroquine-induced scratching in mice
-
Inan S, Cowan A, (2004). Kappa opioid agonists suppress chloroquine-induced scratching in mice. Eur J Pharmacol 502: 233-237.
-
(2004)
Eur J Pharmacol
, vol.502
, pp. 233-237
-
-
Inan, S.1
Cowan, A.2
-
12
-
-
68349137947
-
Nalfurafine prevents 5′-guanidinonaltrindole- and compound 48/80-induced spinal c-fos expression and attenuates 5′-guanidinonaltrindole-elicited scratching behavior in mice
-
Inan S, Dun NJ, Cowan A, (2009). Nalfurafine prevents 5′-guanidinonaltrindole- and compound 48/80-induced spinal c-fos expression and attenuates 5′-guanidinonaltrindole-elicited scratching behavior in mice. Neuroscience 163: 23-33.
-
(2009)
Neuroscience
, vol.163
, pp. 23-33
-
-
Inan, S.1
Dun, N.J.2
Cowan, A.3
-
13
-
-
84863084178
-
Nalfurafine hydrochloride for the treatment of pruritus
-
Inui S, (2012). Nalfurafine hydrochloride for the treatment of pruritus. Expert Opin Pharmacother 13: 1507-1513.
-
(2012)
Expert Opin Pharmacother
, vol.13
, pp. 1507-1513
-
-
Inui, S.1
-
14
-
-
0035917683
-
Norbinaltorphimine, a selective kappa-opioid receptor antagonist, induces an itch-associated response in mice
-
Kamei J, Nagase H, (2001). Norbinaltorphimine, a selective kappa-opioid receptor antagonist, induces an itch-associated response in mice. Eur J Pharmacol 418: 141-145.
-
(2001)
Eur J Pharmacol
, vol.418
, pp. 141-145
-
-
Kamei, J.1
Nagase, H.2
-
15
-
-
77954326944
-
Animal research: Reporting in vivo experiments: The ARRIVE guidelines
-
Kilkenny C, Browne W, Cuthill IC, Emerson M, Altman DG, (2010). Animal research: Reporting in vivo experiments: the ARRIVE guidelines. Br J Pharmacol 160: 1577-1579.
-
(2010)
Br J Pharmacol
, vol.160
, pp. 1577-1579
-
-
Kilkenny, C.1
Browne, W.2
Cuthill, I.C.3
Emerson, M.4
Altman, D.G.5
-
16
-
-
84978521515
-
Roles of central opioid receptor subtypes in regulating itch sensation. Peripheral opioids
-
chapter 25. Carstens E. Akiyama T. (eds). CRC Press: Boca Raton, FL
-
Ko MC, (2014). Roles of central opioid receptor subtypes in regulating itch sensation. Peripheral opioids, chapter 25. In:, Carstens E, Akiyama T, (eds). Itch Mechanisms and Treatment. CRC Press: Boca Raton, FL, pp. 1-10.
-
(2014)
Itch Mechanisms and Treatment
, pp. 1-10
-
-
Ko, M.C.1
-
17
-
-
0034053493
-
An experimental itch model in monkeys: Characterization of intrathecal morphine-induced scratching and antinociception
-
Ko MC, Naughton NN, (2000). An experimental itch model in monkeys: characterization of intrathecal morphine-induced scratching and antinociception. Anesthesiology 92: 795-805.
-
(2000)
Anesthesiology
, vol.92
, pp. 795-805
-
-
Ko, M.C.1
Naughton, N.N.2
-
18
-
-
77950267997
-
Effect of a novel kappa-receptor agonist, nalfurafine hydrochloride, on severe itch in 337 haemodialysis patients: A phase III, randomized, double-blind, placebo-controlled study
-
Kumagai H, Ebata T, Takamori K, Muramatsu T, Nakamoto H, Suzuki H, (2010). Effect of a novel kappa-receptor agonist, nalfurafine hydrochloride, on severe itch in 337 haemodialysis patients: a phase III, randomized, double-blind, placebo-controlled study. Nephrol Dial Transplant 25: 1251-1257.
-
(2010)
Nephrol Dial Transplant
, vol.25
, pp. 1251-1257
-
-
Kumagai, H.1
Ebata, T.2
Takamori, K.3
Muramatsu, T.4
Nakamoto, H.5
Suzuki, H.6
-
19
-
-
0028926504
-
Scratching behavior induced by pruritogenic but not algesiogenic agents in mice
-
Kuraishi Y, Nagasawa T, Hayashi K, Satoh M, (1995). Scratching behavior induced by pruritogenic but not algesiogenic agents in mice. Eur J Pharmacol 275: 229-233.
-
(1995)
Eur J Pharmacol
, vol.275
, pp. 229-233
-
-
Kuraishi, Y.1
Nagasawa, T.2
Hayashi, K.3
Satoh, M.4
-
20
-
-
0034075959
-
Itch-scratch responses induced by opioids through central mu opioid receptors in mice
-
Kuraishi Y, Yamaguchi T, Miyamoto T, (2000). Itch-scratch responses induced by opioids through central mu opioid receptors in mice. J Biomed Sci 7: 248-252.
-
(2000)
J Biomed Sci
, vol.7
, pp. 248-252
-
-
Kuraishi, Y.1
Yamaguchi, T.2
Miyamoto, T.3
-
21
-
-
47749140066
-
In vitro and in vivo characterization of a novel liposomal butorphanol formulation for treatment of pruritus
-
Lim GJ, Ishiuji Y, Dawn A, Harrison B, Kim D, Atala A, et al. (2008). In vitro and in vivo characterization of a novel liposomal butorphanol formulation for treatment of pruritus. Acta Derm Venereol 88: 327-330.
-
(2008)
Acta Derm Venereol
, vol.88
, pp. 327-330
-
-
Lim, G.J.1
Ishiuji, Y.2
Dawn, A.3
Harrison, B.4
Kim, D.5
Atala, A.6
-
22
-
-
80054709876
-
Unidirectional cross-activation of GRPR by MOR1D uncouples itch and analgesia induced by opioids
-
Liu XY, Liu ZC, Sun YG, Ross M, Kim S, Tsai FF, et al. (2011). Unidirectional cross-activation of GRPR by MOR1D uncouples itch and analgesia induced by opioids. Cell 147: 447-458.
-
(2011)
Cell
, vol.147
, pp. 447-458
-
-
Liu, X.Y.1
Liu, Z.C.2
Sun, Y.G.3
Ross, M.4
Kim, S.5
Tsai, F.F.6
-
23
-
-
84877148871
-
Dose-related effects of salvinorin A in humans: Dissociative, hallucinogenic, and memory effects
-
MacLean KA, Johnson MW, Reissig CJ, Prisinzano TE, Griffiths RR, (2013). Dose-related effects of salvinorin A in humans: dissociative, hallucinogenic, and memory effects. Psychopharmacology (Berl) 226: 381-392.
-
(2013)
Psychopharmacology (Berl)
, vol.226
, pp. 381-392
-
-
MacLean, K.A.1
Johnson, M.W.2
Reissig, C.J.3
Prisinzano, T.E.4
Griffiths, R.R.5
-
24
-
-
77954331629
-
Guidelines for reporting experiments involving animals: The ARRIVE guidelines
-
McGrath JC, Drummond GB, McLachlan EM, Kilkenny C, Wainwright CL, (2010). Guidelines for reporting experiments involving animals: the ARRIVE guidelines. Br J Pharmacol 160: 1573-1576.
-
(2010)
Br J Pharmacol
, vol.160
, pp. 1573-1576
-
-
McGrath, J.C.1
Drummond, G.B.2
McLachlan, E.M.3
Kilkenny, C.4
Wainwright, C.L.5
-
25
-
-
0023035581
-
Differentiation of neurochemical basis of stress-induced analgesia in mice by selective breeding
-
Panocka I, Marek P, Sadowski B, (1986). Differentiation of neurochemical basis of stress-induced analgesia in mice by selective breeding. Brain Res 397: 156-160.
-
(1986)
Brain Res
, vol.397
, pp. 156-160
-
-
Panocka, I.1
Marek, P.2
Sadowski, B.3
-
26
-
-
84891791940
-
The IUPHAR/BPS Guide to PHARMACOLOGY: An expert-driven knowledge base of drug targets and their ligands
-
NC-IUPHAR.
-
Pawson AJ, Sharman JL, Benson HE, Faccenda E, Alexander SP, Buneman OP, et al.; NC-IUPHAR (2014). The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledge base of drug targets and their ligands. Nucl Acids Res 42 (Database Issue): D1098-D1106.
-
(2014)
Nucl Acids Res
, vol.42
, Issue.DATABASE ISSUE
, pp. D1098-D1106
-
-
Pawson, A.J.1
Sharman, J.L.2
Benson, H.E.3
Faccenda, E.4
Alexander, S.P.5
Buneman, O.P.6
-
27
-
-
84865590838
-
Systemic kappa opioid receptor agonists in the treatment of chronic pruritus: A literature review
-
Phan NQ, Lotts T, Antal A, Bernhard JD, Stander S, (2012). Systemic kappa opioid receptor agonists in the treatment of chronic pruritus: a literature review. Acta Derm Venereol 92: 555-560.
-
(2012)
Acta Derm Venereol
, vol.92
, pp. 555-560
-
-
Phan, N.Q.1
Lotts, T.2
Antal, A.3
Bernhard, J.D.4
Stander, S.5
-
28
-
-
84876686778
-
Kappa-opioid receptor-selective dicarboxylic ester-derived salvinorin A ligands
-
Polepally PR, White K, Vardy E, Roth BL, Ferreira D, Zjawiony JK, (2013). Kappa-opioid receptor-selective dicarboxylic ester-derived salvinorin A ligands. Bioorg Med Chem Lett 23: 2860-2862.
-
(2013)
Bioorg Med Chem Lett
, vol.23
, pp. 2860-2862
-
-
Polepally, P.R.1
White, K.2
Vardy, E.3
Roth, B.L.4
Ferreira, D.5
Zjawiony, J.K.6
-
29
-
-
84930245171
-
Michael acceptor approach to the design of new salvinorin A-based high affinity ligands for the kappa-opioid receptor
-
Polepally PR, Huben K, Vardy E, Setola V, Mosier PD, Roth BL, et al. (2014). Michael acceptor approach to the design of new salvinorin A-based high affinity ligands for the kappa-opioid receptor. Eur J Med Chem 85: 818-829.
-
(2014)
Eur J Med Chem
, vol.85
, pp. 818-829
-
-
Polepally, P.R.1
Huben, K.2
Vardy, E.3
Setola, V.4
Mosier, P.D.5
Roth, B.L.6
-
30
-
-
84867746318
-
Dose-related behavioral, subjective, endocrine, and psychophysiological effects of the kappa opioid agonist salvinorin A in humans
-
Ranganathan M, Schnakenberg A, Skosnik PD, Cohen BM, Pittman B, Sewell RA, et al. (2012). Dose-related behavioral, subjective, endocrine, and psychophysiological effects of the kappa opioid agonist salvinorin A in humans. Biol Psychiatry 72: 871-879.
-
(2012)
Biol Psychiatry
, vol.72
, pp. 871-879
-
-
Ranganathan, M.1
Schnakenberg, A.2
Skosnik, P.D.3
Cohen, B.M.4
Pittman, B.5
Sewell, R.A.6
-
31
-
-
84881163458
-
Inhibition of proteases as a novel therapeutic strategy in the treatment of metabolic, inflammatory and functional diseases of the gastrointestinal tract
-
Salaga M, Sobczak M, Fichna J, (2013). Inhibition of proteases as a novel therapeutic strategy in the treatment of metabolic, inflammatory and functional diseases of the gastrointestinal tract. Drug Discov Today 18: 708-715.
-
(2013)
Drug Discov Today
, vol.18
, pp. 708-715
-
-
Salaga, M.1
Sobczak, M.2
Fichna, J.3
-
32
-
-
84906790983
-
Experimental colitis in mice is attenuated by changes in the levels of endocannabinoid metabolites induced by selective inhibition of fatty acid amide hydrolase (FAAH)
-
Salaga M, Mokrowiecka A, Zakrzewski PK, Cygankiewicz A, Leishman E, Sobczak M, et al. (2014a). Experimental colitis in mice is attenuated by changes in the levels of endocannabinoid metabolites induced by selective inhibition of fatty acid amide hydrolase (FAAH). J Crohns Colitis 8: 998-1009.
-
(2014)
J Crohns Colitis
, vol.8
, pp. 998-1009
-
-
Salaga, M.1
Mokrowiecka, A.2
Zakrzewski, P.K.3
Cygankiewicz, A.4
Leishman, E.5
Sobczak, M.6
-
33
-
-
84903532606
-
Novel orally available salvinorin A analog PR-38 inhibits gastrointestinal motility and reduces abdominal pain in mouse models mimicking irritable bowel syndrome
-
Salaga M, Polepally PR, Sobczak M, Grzywacz D, Kamysz W, Sibaev A, et al. (2014b). Novel orally available salvinorin A analog PR-38 inhibits gastrointestinal motility and reduces abdominal pain in mouse models mimicking irritable bowel syndrome. J Pharmacol Exp Ther 350: 69-78.
-
(2014)
J Pharmacol Exp Ther
, vol.350
, pp. 69-78
-
-
Salaga, M.1
Polepally, P.R.2
Sobczak, M.3
Grzywacz, D.4
Kamysz, W.5
Sibaev, A.6
-
34
-
-
84912083696
-
Novel orally available salvinorin A analog PR-38 protects against experimental colitis and reduces abdominal pain in mice by interaction with opioid and cannabinoid receptors
-
Salaga M, Polepally PR, Zakrzewski PK, Cygankiewicz A, Sobczak M, Kordek R, et al. (2014c). Novel orally available salvinorin A analog PR-38 protects against experimental colitis and reduces abdominal pain in mice by interaction with opioid and cannabinoid receptors. Biochem Pharmacol 92: 618-626.
-
(2014)
Biochem Pharmacol
, vol.92
, pp. 618-626
-
-
Salaga, M.1
Polepally, P.R.2
Zakrzewski, P.K.3
Cygankiewicz, A.4
Sobczak, M.5
Kordek, R.6
-
35
-
-
84895075426
-
Physiology, signaling, and pharmacology of opioid receptors and their ligands in the gastrointestinal tract: Current concepts and future perspectives
-
Sobczak M, Salaga M, Storr MA, Fichna J, (2014). Physiology, signaling, and pharmacology of opioid receptors and their ligands in the gastrointestinal tract: current concepts and future perspectives. J Gastroenterol 49: 24-45.
-
(2014)
J Gastroenterol
, vol.49
, pp. 24-45
-
-
Sobczak, M.1
Salaga, M.2
Storr, M.A.3
Fichna, J.4
-
36
-
-
84920183889
-
Anti-nociception mediated by a kappa opioid receptor agonist is blocked by a delta receptor agonist
-
Taylor AM, Roberts KW, Pradhan AA, Akbari HA, Walwyn W, Lutfy K, et al. (2014). Anti-nociception mediated by a kappa opioid receptor agonist is blocked by a delta receptor agonist. Br J Pharmacol 172: 691-703.
-
(2014)
Br J Pharmacol
, vol.172
, pp. 691-703
-
-
Taylor, A.M.1
Roberts, K.W.2
Pradhan, A.A.3
Akbari, H.A.4
Walwyn, W.5
Lutfy, K.6
-
37
-
-
0037169176
-
Antipruritic activity of the kappa-opioid receptor agonist, TRK-820
-
Togashi Y, Umeuchi H, Okano K, Ando N, Yoshizawa Y, Honda T, et al. (2002). Antipruritic activity of the kappa-opioid receptor agonist, TRK-820. Eur J Pharmacol 435: 259-264.
-
(2002)
Eur J Pharmacol
, vol.435
, pp. 259-264
-
-
Togashi, Y.1
Umeuchi, H.2
Okano, K.3
Ando, N.4
Yoshizawa, Y.5
Honda, T.6
-
38
-
-
34547922417
-
Possible roles of epidermal opioid systems in pruritus of atopic dermatitis
-
Tominaga M, Ogawa H, Takamori K, (2007). Possible roles of epidermal opioid systems in pruritus of atopic dermatitis. J Invest Dermatol 127: 2228-2235.
-
(2007)
J Invest Dermatol
, vol.127
, pp. 2228-2235
-
-
Tominaga, M.1
Ogawa, H.2
Takamori, K.3
-
39
-
-
1642408015
-
Involvement of central mu-opioid system in the scratching behavior in mice, and the suppression of it by the activation of kappa-opioid system
-
Umeuchi H, Togashi Y, Honda T, Nakao K, Okano K, Tanaka T, et al. (2003). Involvement of central mu-opioid system in the scratching behavior in mice, and the suppression of it by the activation of kappa-opioid system. Eur J Pharmacol 477: 29-35.
-
(2003)
Eur J Pharmacol
, vol.477
, pp. 29-35
-
-
Umeuchi, H.1
Togashi, Y.2
Honda, T.3
Nakao, K.4
Okano, K.5
Tanaka, T.6
-
40
-
-
77955299009
-
Automated quantitative gait analysis in animal models of movement disorders
-
Vandeputte C, Taymans JM, Casteels C, Coun F, Ni Y, Van LK, et al. (2010). Automated quantitative gait analysis in animal models of movement disorders. BMC Neurosci 11: 92.
-
(2010)
BMC Neurosci
, vol.11
, pp. 92
-
-
Vandeputte, C.1
Taymans, J.M.2
Casteels, C.3
Coun, F.4
Ni, Y.5
Van, L.K.6
-
41
-
-
19944426642
-
Comparison of pharmacological activities of three distinct kappa ligands (salvinorin A, TRK-820 and 3FLB) on kappa opioid receptors in vitro and their antipruritic and antinociceptive activities in vivo
-
Wang Y, Tang K, Inan S, Siebert D, Holzgrabe U, Lee DY, et al. (2005). Comparison of pharmacological activities of three distinct kappa ligands (salvinorin A, TRK-820 and 3FLB) on kappa opioid receptors in vitro and their antipruritic and antinociceptive activities in vivo. J Pharmacol Exp Ther 312: 220-230.
-
(2005)
J Pharmacol Exp Ther
, vol.312
, pp. 220-230
-
-
Wang, Y.1
Tang, K.2
Inan, S.3
Siebert, D.4
Holzgrabe, U.5
Lee, D.Y.6
-
42
-
-
33645952393
-
Kappa-opioid system in uremic pruritus: Multicenter, randomized, double-blind, placebo-controlled clinical studies
-
Wikstrom B, Gellert R, Ladefoged SD, Danda Y, Akai M, Ide K, et al. (2005). Kappa-opioid system in uremic pruritus: multicenter, randomized, double-blind, placebo-controlled clinical studies. J Am Soc Nephrol 16: 3742-3747.
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 3742-3747
-
-
Wikstrom, B.1
Gellert, R.2
Ladefoged, S.D.3
Danda, Y.4
Akai, M.5
Ide, K.6
|