Ex vivo immunosuppressive effects of mesenchymal stem cells on Crohn's disease mucosal T cells are largely dependent on indoleamine 2,3-dioxygenase activity and cell-cell contact

Stem Cell Research and Therapy

Volumn 6, Issue 1, 2015, Pages

  Ciccocioppo, Rachele ^a   Cangemi, Giuseppina C ^a   Kruzliak, Peter ^b   Gallia, Alessandra ^a   Betti, Elena ^a   Badulli, Carla ^a   Martinetti, Miryam ^a   Cervio, Marila ^a   Pecci, Alessandro ^a   Bozzi, Valeria ^a   Dionigi, Paolo ^a   Visai, Livia ^a   Gurrado, Antonella ^c   Alvisi, Costanza ^a   Picone, Cristina ^c   Monti, Manuela ^c   Bernardo, Maria E ^d   Gobbi, Paolo ^a   Corazza, Gino R ^a  

^a UNIVERSITY OF PAVIA   (Italy)

^b ST ANNE S UNIVERSITY HOSPITAL   (Czech Republic)

^c FONDAZIONE IRCCS POLICLINICO SAN MATTEO   (Italy)

^d BAMBINO GESÙ CHILDREN S HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INDOLEAMINE 2,3 DIOXYGENASE; INTERLEUKIN 17; INTERLEUKIN 21; INTERLEUKIN 6; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; 1-METHYLTRYPTOPHAN; CYTOKINE; HLA G ANTIGEN; MEMBRANE ANTIGEN; N ACETYLMURAMYLALANYL DEXTRO ISOGLUTAMINE; TRYPTOPHAN;

ADULT; AGED; APOPTOSIS; ARTICLE; CD4+ CD25+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL CONTACT; CELL COUNT; CELL PROLIFERATION; CELL VIABILITY; CLINICAL ARTICLE; CROHN DISEASE; CYTOKINE PRODUCTION; ENZYME ACTIVITY; FEMALE; HUMAN; IMMUNOMODULATION; IMMUNOPHENOTYPING; LYMPHOCYTE SUBPOPULATION; MALE; MESENCHYMAL STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE; UPREGULATION; VERY ELDERLY; ADOLESCENT; ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; BONE MARROW CELL; CELL CULTURE; CELL SURVIVAL; COCULTURE; CYTOLOGY; DRUG EFFECTS; GENETICS; IMMUNOLOGY; INTESTINE MUCOSA; MESENCHYMAL STROMA CELL; METABOLISM; MIDDLE AGED; PATHOLOGY; RNA INTERFERENCE; TIME LAPSE IMAGING; YOUNG ADULT;

ACETYLMURAMYL-ALANYL-ISOGLUTAMINE; ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, SURFACE; APOPTOSIS; BONE MARROW CELLS; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; COCULTURE TECHNIQUES; CROHN DISEASE; CYTOKINES; FEMALE; HLA-G ANTIGENS; HUMANS; IMMUNOPHENOTYPING; INDOLEAMINE-PYRROLE 2,3,-DIOXYGENASE; INTESTINAL MUCOSA; MALE; MESENCHYMAL STROMAL CELLS; MIDDLE AGED; RNA INTERFERENCE; RNA, SMALL INTERFERING; T-LYMPHOCYTES; TIME-LAPSE IMAGING; TRYPTOPHAN; YOUNG ADULT;

EID: 84938701181     PISSN: None     EISSN: 17576512     Source Type: Journal    
DOI: 10.1186/s13287-015-0122-1     Document Type: Article

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