-
1
-
-
8844270812
-
Vascular risk factors, incidence of MCI, and rates of progression to dementia
-
Solfrizzi V, Panza F, Colacicco AM, et al. Vascular risk factors, incidence of MCI, and rates of progression to dementia. Neurology 2004;63:1882-91.
-
(2004)
Neurology
, vol.63
, pp. 1882-1891
-
-
Solfrizzi, V.1
Panza, F.2
Colacicco, A.M.3
-
2
-
-
28444491100
-
Cognitive decline and dementia in diabetes-systematic overview of prospective observational studies
-
Cukierman T, Gerstein HC, Williamson JD. Cognitive decline and dementia in diabetes-systematic overview of prospective observational studies. Diabetologia 2005;48:2460-9.
-
(2005)
Diabetologia
, vol.48
, pp. 2460-2469
-
-
Cukierman, T.1
Gerstein, H.C.2
Williamson, J.D.3
-
4
-
-
0028271689
-
The survival of rat cerebral cortical neurons in the presence of trophic APP peptide
-
Yamamoto KT, Miyoshi T, Yea K, et al. The survival of rat cerebral cortical neurons in the presence of trophic APP peptide. J Neurobiol 1994;25:585-94.
-
(1994)
J Neurobiol
, vol.25
, pp. 585-594
-
-
Yamamoto, K.T.1
Miyoshi, T.2
Yea, K.3
-
5
-
-
84869501606
-
Changes in insulin-signaling transduction pathway underlie learning/memory deficits in an Alzheimer's disease rat model
-
Han X, Ma Y, Liu X, et al. Changes in insulin-signaling transduction pathway underlie learning/memory deficits in an Alzheimer's disease rat model. J Neural Transm 2012;119:1407-16.
-
(2012)
J Neural Transm
, vol.119
, pp. 1407-1416
-
-
Han, X.1
Ma, Y.2
Liu, X.3
-
7
-
-
84885952847
-
Risk score for prediction of 10 year dementia risk in individuals with type 2 diabetes: A cohort study
-
Exalto LG, Biessels GJ, Karter AJ, et al. Risk score for prediction of 10 year dementia risk in individuals with type 2 diabetes: a cohort study. Lancet Diabetes Endocrinol 2013;1:164-5.
-
(2013)
Lancet Diabetes Endocrinol
, vol.1
, pp. 164-165
-
-
Exalto, L.G.1
Biessels, G.J.2
Karter, A.J.3
-
8
-
-
46749101381
-
The effects of rosiglitazone on oxidative stress and lipid profile in left ventricular muscles of diabetic rats
-
Kavak S, Ayaz L, Emre M, et al. The effects of rosiglitazone on oxidative stress and lipid profile in left ventricular muscles of diabetic rats. Cell Biochem Funct 2008;26:478-85.
-
(2008)
Cell Biochem Funct
, vol.26
, pp. 478-485
-
-
Kavak, S.1
Ayaz, L.2
Emre, M.3
-
9
-
-
13644271368
-
Peroxisome proliferator-activated receptor g is expressed in hippocampal neurons and its activation prevents b-amyloid neurodegeneration: Role of Wnt signaling
-
Inestrosa NC, Godoy JA, Quintanilla RA, et al. Peroxisome proliferator-activated receptor g is expressed in hippocampal neurons and its activation prevents b-amyloid neurodegeneration: role of Wnt signaling. Exp Cell Res 2005;304:91-104.
-
(2005)
Exp Cell Res
, vol.304
, pp. 91-104
-
-
Inestrosa, N.C.1
Godoy, J.A.2
Quintanilla, R.A.3
-
10
-
-
0034651101
-
Inflammatory mechanisms in Alzheimer's disease: Inhibition of beta-amyloid-stimulated proinflammatory responses and neurotoxicity by PPARgamma agonists
-
Combs CK, Johnson DE, Karlo JC, et al. Inflammatory mechanisms in Alzheimer's disease: inhibition of beta-amyloid-stimulated proinflammatory responses and neurotoxicity by PPARgamma agonists. J Neurosci 2000;20:558-67.
-
(2000)
J Neurosci
, vol.20
, pp. 558-567
-
-
Combs, C.K.1
Johnson, D.E.2
Karlo, J.C.3
-
11
-
-
0242609178
-
Nonsteroidal antiinflammatory drugs and peroxisome proliferator-activated receptorgamma agonists modulate immunostimulated processing of amyloid precursor protein through regulation of beta-secretase
-
Sastre M, Dewachter I, Landreth GE, et al. Nonsteroidal antiinflammatory drugs and peroxisome proliferator-activated receptorgamma agonists modulate immunostimulated processing of amyloid precursor protein through regulation of beta-secretase. J Neurosci 2003;23:9796-804.
-
(2003)
J Neurosci
, vol.23
, pp. 9796-9804
-
-
Sastre, M.1
Dewachter, I.2
Landreth, G.E.3
-
12
-
-
0034603858
-
Roles for insulin receptor, PI3-kinase, and Akt in insulin-signaling pathways related to production of nitric oxide in human vascular endothelial cells
-
Zeng G, Nystrom FH, Ravichandran LV, et al. Roles for insulin receptor, PI3-kinase, and Akt in insulin-signaling pathways related to production of nitric oxide in human vascular endothelial cells. Circulation 2000;101:1539-45.
-
(2000)
Circulation
, vol.101
, pp. 1539-1545
-
-
Zeng, G.1
Nystrom, F.H.2
Ravichandran, L.V.3
-
13
-
-
33644592598
-
Preserved cognition in patients with early Alzheimer disease and amnestic mild cognitive impairment during treatment with rosiglitazone: A preliminary study
-
Watson GS, Cholerton BA, Reger MA, et al. Preserved cognition in patients with early Alzheimer disease and amnestic mild cognitive impairment during treatment with rosiglitazone: a preliminary study. Am J Geriatr Psychiatry 2005;13:950-8.
-
(2005)
Am J Geriatr Psychiatry
, vol.13
, pp. 950-958
-
-
Watson, G.S.1
Cholerton, B.A.2
Reger, M.A.3
-
14
-
-
0015384891
-
Determination of protein: A modification of the Lowry method that gives a linear photometric response
-
Hartree EF. Determination of protein: a modification of the Lowry method that gives a linear photometric response. Anal Biochem 1972; 48:422-7.
-
(1972)
Anal Biochem
, vol.48
, pp. 422-427
-
-
Hartree, E.F.1
-
15
-
-
84857640868
-
The insulin and insulin-like growth factor receptor family in neoplasia: An update
-
Pollak M. The insulin and insulin-like growth factor receptor family in neoplasia: an update. Nat Rev Cancer 2012;12:159-69.
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 159-169
-
-
Pollak, M.1
-
16
-
-
84875228139
-
Alpha-synuclein elicits glucose uptake and utilization in adipocytes through the Gab1/PI3K/Akt transduction pathway
-
Rodriguez-Araujo G, Nakagami H, Hayashi H, et al. Alpha-synuclein elicits glucose uptake and utilization in adipocytes through the Gab1/PI3K/Akt transduction pathway. Cell Mol Life Sci 2013;70:1123-33.
-
(2013)
Cell Mol Life Sci
, vol.70
, pp. 1123-1133
-
-
Rodriguez-Araujo, G.1
Nakagami, H.2
Hayashi, H.3
-
17
-
-
0031019043
-
Insulin and insulin-like growth factor in normal and pathological cardiovascular physiology
-
Sowers JR. Insulin and insulin-like growth factor in normal and pathological cardiovascular physiology. Hypertension 1997;29:691-9.
-
(1997)
Hypertension
, vol.29
, pp. 691-699
-
-
Sowers, J.R.1
-
18
-
-
68949089312
-
Alzheimer's disease is type 3 diabetesevidence reviewed
-
de la Monte SM, Wands JR. Alzheimer's disease is type 3 diabetesevidence reviewed. J Diabetes Sci Technol 2008;2:1101-13.
-
(2008)
J Diabetes Sci Technol
, vol.2
, pp. 1101-1113
-
-
De La Monte, S.M.1
Wands, J.R.2
-
20
-
-
84862852400
-
Network-level and population genetics analysis of the insulin/TOR signal transduction pathway across human populations
-
Luisi P, Alvarez-Ponce D, Dall'Olio GM, et al. Network-level and population genetics analysis of the insulin/TOR signal transduction pathway across human populations. Mol Biol Evol 2012;29:1379-92.
-
(2012)
Mol Biol Evol
, vol.29
, pp. 1379-1392
-
-
Luisi, P.1
Alvarez-Ponce, D.2
Dall'Olio, G.M.3
-
21
-
-
1542289063
-
Amino acids and insulin control autophagic proteolysis through different signaling pathways in relation to mTOR in isolated rat hepatocytes
-
Kanazawa T, Taneike I, Akaishi R, et al. Amino acids and insulin control autophagic proteolysis through different signaling pathways in relation to mTOR in isolated rat hepatocytes. J Biol Chem 2004;279: 8452-9.
-
(2004)
J Biol Chem
, vol.279
, pp. 8452-8459
-
-
Kanazawa, T.1
Taneike, I.2
Akaishi, R.3
-
22
-
-
0000664619
-
Expression of two glucose transporters, GLUT1 and GLUT3, in cultured cerebellar neurons: Evidence for neuron-specific expression of GLUT3
-
Maher F, Davies-Hill TM, Lysko PG, et al. Expression of two glucose transporters, GLUT1 and GLUT3, in cultured cerebellar neurons: evidence for neuron-specific expression of GLUT3. Mol Cell Neurosci 1991;2:351-60.
-
(1991)
Mol Cell Neurosci
, vol.2
, pp. 351-360
-
-
Maher, F.1
Davies-Hill, T.M.2
Lysko, P.G.3
-
23
-
-
9444237919
-
Phosphatidylinositol 3-kinase and Akt effectors mediate insulin-like growth factor-I neuroprotection in dorsal root ganglia neurons
-
Leinninger GM, Backus C, Uhler MD, et al. Phosphatidylinositol 3-kinase and Akt effectors mediate insulin-like growth factor-I neuroprotection in dorsal root ganglia neurons. FASEB J 2004;18:1544-6.
-
(2004)
FASEB J
, vol.18
, pp. 1544-1546
-
-
Leinninger, G.M.1
Backus, C.2
Uhler, M.D.3
-
24
-
-
20444394386
-
Inhibition of GSK3b is a common event in neuroprotection by different survival factors
-
Chin PC, Majdzadeh N, D'Mello SR. Inhibition of GSK3b is a common event in neuroprotection by different survival factors. Mol Brain Res 2005;137:193-201.
-
(2005)
Mol Brain Res
, vol.137
, pp. 193-201
-
-
Chin, P.C.1
Majdzadeh, N.2
D'Mello, S.R.3
-
25
-
-
12144290448
-
Role for neuronal insulin resistance in neurodegenerative diseases
-
U S A
-
Schubert M, Gautam D, Surjo D, et al. Role for neuronal insulin resistance in neurodegenerative diseases. Proc Natl Acad Sci U S A 2004;101:3100-5.
-
(2004)
Proc Natl Acad Sci
, vol.101
, pp. 3100-3105
-
-
Schubert, M.1
Gautam, D.2
Surjo, D.3
-
26
-
-
59049094829
-
Nutrient deprivation induces neuronal autophagy and implicates reduced insulin signaling in neuroprotective autophagy activation
-
Young JE, Martinez RA, La Spada AR. Nutrient deprivation induces neuronal autophagy and implicates reduced insulin signaling in neuroprotective autophagy activation. J Biol Chem 2009;284:2363-73.
-
(2009)
J Biol Chem
, vol.284
, pp. 2363-2373
-
-
Young, J.E.1
Martinez, R.A.2
La Spada, A.R.3
-
27
-
-
84880726942
-
Beta-amyloid monomer and insulin/IGF-1 signaling in Alzheimer's disease
-
Giuffrida ML, Tomasello F, Caraci F, et al. Beta-amyloid monomer and insulin/IGF-1 signaling in Alzheimer's disease. Mol Neurobiol 2012;46:605-13.
-
(2012)
Mol Neurobiol
, vol.46
, pp. 605-613
-
-
Giuffrida, M.L.1
Tomasello, F.2
Caraci, F.3
-
28
-
-
15244351255
-
Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease-is this type 3 diabetes
-
Steen E, Terry BM, Rivera EJ, et al. Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease-is this type 3 diabetes? J Alzheimers Dis 2005;7:63-80.
-
(2005)
J Alzheimers Dis
, vol.7
, pp. 63-80
-
-
Steen, E.1
Terry, B.M.2
Rivera, E.J.3
-
29
-
-
84858336588
-
Ab-induced formation of autophagosomes is mediated by RAGE-CaMKKb-AMPK signaling
-
Son SM, Jung ES, Shin HJ, et al. Ab-induced formation of autophagosomes is mediated by RAGE-CaMKKb-AMPK signaling. Neurobiol Aging 2012;33:11-23.
-
(2012)
Neurobiol Aging
, vol.33
, pp. 11-23
-
-
Son, S.M.1
Jung, E.S.2
Shin, H.J.3
-
30
-
-
79957902168
-
Cytokine production and inflammation drive autophagy in the tumor microenvironment: Role of stromal caveolin-1 as a key regulator
-
Martinez-Outschoorn UE, Whitaker-Menezes D, Lin Z, et al. Cytokine production and inflammation drive autophagy in the tumor microenvironment: role of stromal caveolin-1 as a key regulator. Cell Cycle 2011;10:1784-93.
-
(2011)
Cell Cycle
, vol.10
, pp. 1784-1793
-
-
Martinez-Outschoorn, U.E.1
Whitaker-Menezes, D.2
Lin, Z.3
-
31
-
-
60949108484
-
Protective effect of berberine on beta cells in streptozotocin-and high-carbohydrate/high-fat diet-induced diabetic rats
-
Zhou J, Zhou S, Tang J, et al. Protective effect of berberine on beta cells in streptozotocin-and high-carbohydrate/high-fat diet-induced diabetic rats. Eur J Pharmacol 2009;606:262-8.
-
(2009)
Eur J Pharmacol
, vol.606
, pp. 262-268
-
-
Zhou, J.1
Zhou, S.2
Tang, J.3
-
32
-
-
0037221379
-
The role of insulin-resistance in the pathogenesis of Alzheimer's disease: Implications for treatment
-
Watson GS, Craft S. The role of insulin-resistance in the pathogenesis of Alzheimer's disease: implications for treatment. CNS Drugs 2003;17:27-45.
-
(2003)
CNS Drugs
, vol.17
, pp. 27-45
-
-
Watson, G.S.1
Craft, S.2
-
33
-
-
78650236128
-
Microdialysis combined blood sampling technique for the determination of rosiglitazone and glucose in brain and blood of gerbils subjected to cerebral ischemia
-
Sheu WH, Chuang HC, Cheng SM, et al. Microdialysis combined blood sampling technique for the determination of rosiglitazone and glucose in brain and blood of gerbils subjected to cerebral ischemia. J Pharm Biomed Anal 2011;54:759-64.
-
(2011)
J Pharm Biomed Anal
, vol.54
, pp. 759-764
-
-
Sheu, W.H.1
Chuang, H.C.2
Cheng, S.M.3
-
34
-
-
84455185141
-
PPAR,gamma agonist improves neuronal insulin receptor function in hippocampus and brain mitochondria function in rats with insulin resistance induced by long term high-fat diets
-
Noppamas P, Wasana P, Nipon C, et al. PPAR,gamma. Agonist improves neuronal insulin receptor function in hippocampus and brain mitochondria function in rats with insulin resistance induced by long term high-fat diets. Endocrinology 2012;153:329-38.
-
(2012)
Endocrinology
, vol.153
, pp. 329-338
-
-
Noppamas, P.1
Wasana, P.2
Nipon, C.3
-
35
-
-
39549091493
-
Rosiglitazone increases dendritic spine density and rescues spine loss caused by apolipoprotein E4 in primary cortical neurons
-
U S A
-
Brodbeck J, Balestra ME, Saunders AM, et al. Rosiglitazone increases dendritic spine density and rescues spine loss caused by apolipoprotein E4 in primary cortical neurons. Proc Natl Acad Sci U S A 2008;105:1343-6.
-
(2008)
Proc Natl Acad Sci
, vol.105
, pp. 1343-1346
-
-
Brodbeck, J.1
Balestra, M.E.2
Saunders, A.M.3
-
36
-
-
57049125529
-
Defective insulin signaling pathway and increased glycogen synthase kinase-3 activity in the brain of diabetic mice: Parallels with Alzheimer's disease and correction by insulin
-
Jolivalt CG, Lee CA, Beiswenger KK, et al. Defective insulin signaling pathway and increased glycogen synthase kinase-3 activity in the brain of diabetic mice: parallels with Alzheimer's disease and correction by insulin. J Neurosci Res 2008;86:3265-74.
-
(2008)
J Neurosci Res
, vol.86
, pp. 3265-3274
-
-
Jolivalt, C.G.1
Lee, C.A.2
Beiswenger, K.K.3
-
37
-
-
33745234766
-
Rosiglitazone attenuates learning and memory deficits in Tg2576 Alzheimer mice
-
Pedersen WA, McMillan PJ, Kulstad JJ, et al. Rosiglitazone attenuates learning and memory deficits in Tg2576 Alzheimer mice. Exp Neurol 2006;199:265-73.
-
(2006)
Exp Neurol
, vol.199
, pp. 265-273
-
-
Pedersen, W.A.1
McMillan, P.J.2
Kulstad, J.J.3
-
38
-
-
9644268167
-
Insulin resistance contributes to aberrant stress responses in the Tg2576 mouse model of Alzheimer's disease
-
Pedersen WA, Flynn ER. Insulin resistance contributes to aberrant stress responses in the Tg2576 mouse model of Alzheimer's disease. Neurobiol Dis 2004;17:500-6.
-
(2004)
Neurobiol Dis
, vol.17
, pp. 500-506
-
-
Pedersen, W.A.1
Flynn, E.R.2
-
39
-
-
84868282388
-
Insulin in central nervous system: More than just a peripheral hormone
-
Duarte AI, Moreira PI, Oliveira CR. Insulin in central nervous system: more than just a peripheral hormone. J Aging Res 2012;2012: 384017.
-
(2012)
J Aging Res
, vol.2012
, pp. 384017
-
-
Duarte, A.I.1
Moreira, P.I.2
Oliveira, C.R.3
-
40
-
-
43549087343
-
Insulin neuroprotection against oxidative stress is mediated by Akt and GSK-3b signaling pathways and changes in protein expression
-
Duarte AI, Santos P, Oliveira CR, et al. Insulin neuroprotection against oxidative stress is mediated by Akt and GSK-3b signaling pathways and changes in protein expression. Biochim Biophys Acta 2008; 1783:994-1002.
-
(2008)
Biochim Biophys Acta
, vol.1783
, pp. 994-1002
-
-
Duarte, A.I.1
Santos, P.2
Oliveira, C.R.3
-
41
-
-
33750882488
-
Insulin restores metabolic function in cultured cortical neurons subjected to oxidative stress
-
Duarte AI, Proença T, Oliveira CR, et al. Insulin restores metabolic function in cultured cortical neurons subjected to oxidative stress. Diabetes 2006;55:2863-70.
-
(2006)
Diabetes
, vol.55
, pp. 2863-2870
-
-
Duarte, A.I.1
Proença, T.2
Oliveira, C.R.3
-
42
-
-
0037303635
-
Brain insulin: Regulation, mechanisms of action and functions
-
Gerozissis K. Brain insulin: regulation, mechanisms of action and functions. Cell Mol Neurobiol 2003;23:1-25.
-
(2003)
Cell Mol Neurobiol
, vol.23
, pp. 1-25
-
-
Gerozissis, K.1
|