Engineering activated protein C to maximize therapeutic efficacy

Biochemical Society Transactions

Volumn 43, Issue , 2015, Pages 691-695

  Quinn, Louise M ^a,b   Drakeford, Clive ^a,b   O'Donnell, James S ^a   Preston, Roger J S ^a,b  

^a TRINITY COLLEGE DUBLIN   (Ireland)

^b OUR LADY S CHILDREN S HOSPITAL   (Ireland)

Author keywords

Activated protein C; Anti coagulant; Inflammation; Protease activated receptor 1; Sepsis

Indexed keywords

DROTRECOGIN; ANTIINFLAMMATORY AGENT; PROTEIN C; RECOMBINANT PROTEIN;

ANTICOAGULATION; ARTICLE; BLEEDING; BLOOD CLOTTING; BLOOD VESSEL INJURY; CHRONIC INFLAMMATION; DISEASE SEVERITY; DRUG EFFICACY; DRUG SAFETY; DRUG TREATMENT FAILURE; HUMAN; INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ENGINEERING; RISK ASSESSMENT; RISK REDUCTION; SEPSIS; SIGNAL TRANSDUCTION; THERAPY EFFECT; ANIMAL; GENETICS; METABOLISM; PROCEDURES;

ANIMALIA;

ANIMALS; ANTI-INFLAMMATORY AGENTS; HUMANS; INFLAMMATION; PROTEIN C; PROTEIN ENGINEERING; RECOMBINANT PROTEINS;

EID: 84938677855     PISSN: 03005127     EISSN: 14708752     Source Type: Journal    
DOI: 10.1042/BST20140312     Document Type: Article

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