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Volumn 75, Issue 12, 2015, Pages 2553-2565

Lin28B/Let-7 regulates expression of Oct4 and Sox2 and reprograms oral squamous cell carcinoma cells to a stem-like state

Author keywords

[No Author keywords available]

Indexed keywords

HERMES ANTIGEN; HIGH MOBILITY GROUP A2 PROTEIN; MEMBRANE PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN ALDH1; PROTEIN ARID3B; PROTEIN LET7; PROTEIN LIN28B; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG; LIN28B PROTEIN, HUMAN; MICRORNA; MIRNLET7 MICRORNA, HUMAN; POU5F1 PROTEIN, HUMAN; RNA BINDING PROTEIN; SOX2 PROTEIN, HUMAN; TRANSCRIPTION FACTOR SOX;

EID: 84938659491     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-14-2215     Document Type: Article
Times cited : (115)

References (50)
  • 1
    • 33646568784 scopus 로고    scopus 로고
    • Patterns of cancer incidence, mortality, and prevalence across five continents: Defining priorities to reduce cancer disparities in different geographic regions of the world
    • Kamangar F, Dores GM, Anderson WF. Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world. J Clin Oncol 2006; 24: 2137-50.
    • (2006) J Clin Oncol , vol.24 , pp. 2137-2150
    • Kamangar, F.1    Dores, G.M.2    Anderson, W.F.3
  • 3
    • 18844392836 scopus 로고    scopus 로고
    • Ectopicexpression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues
    • Hochedlinger K, Yamada Y, Beard C, Jaenisch R. Ectopicexpression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues. Cell 2005; 121: 465-77.
    • (2005) Cell , vol.121 , pp. 465-477
    • Hochedlinger, K.1    Yamada, Y.2    Beard, C.3    Jaenisch, R.4
  • 4
    • 78650389774 scopus 로고    scopus 로고
    • Coexpression of oct4 and nanog enhances malignancy in lung adenocarcinoma by inducing cancer stem cell-like properties and epithelial-mesenchymal transdifferentiation
    • Chiou SH, Wang ML, Chou YT, Chen CJ, Hong CF, Hsieh WJ, et al. Coexpression of oct4 and nanog enhances malignancy in lung adenocarcinoma by inducing cancer stem cell-like properties and epithelial-mesenchymal transdifferentiation. Cancer Res 2010; 70: 10433-44.
    • (2010) Cancer Res , vol.70 , pp. 10433-10444
    • Chiou, S.H.1    Wang, M.L.2    Chou, Y.T.3    Chen, C.J.4    Hong, C.F.5    Hsieh, W.J.6
  • 5
    • 84894109473 scopus 로고    scopus 로고
    • Premature termination of reprogramming in vivo leads to cancer development through altered epigenetic regulation
    • Ohnishi K, Semi K, Yamamoto T, Shimizu M, Tanaka A, Mitsunaga K, et al. Premature termination of reprogramming in vivo leads to cancer development through altered epigenetic regulation. Cell 2014; 156: 663-77.
    • (2014) Cell , vol.156 , pp. 663-677
    • Ohnishi, K.1    Semi, K.2    Yamamoto, T.3    Shimizu, M.4    Tanaka, A.5    Mitsunaga, K.6
  • 6
    • 70349820140 scopus 로고    scopus 로고
    • Lin28 recruits the TUTase Zcchc11 to inhibit let-7 maturation in mouse embryonic stem cells
    • Hagan JP, Piskounova E, Gregory RI. Lin28 recruits the TUTase Zcchc11 to inhibit let-7 maturation in mouse embryonic stem cells. Nat Struct Mol Biol 2009; 16: 1021-5.
    • (2009) Nat Struct Mol Biol , vol.16 , pp. 1021-1025
    • Hagan, J.P.1    Piskounova, E.2    Gregory, R.I.3
  • 8
    • 84881460310 scopus 로고    scopus 로고
    • The Lin28b-let-7-Hmga2 axis determines the higher self-renewal potential of fetal haematopoietic stem cells
    • Copley MR, Babovic S, Benz C, Knapp DJ, Beer PA, Kent DG, et al. The Lin28b-let-7-Hmga2 axis determines the higher self-renewal potential of fetal haematopoietic stem cells. Nat Cell Biol 2013; 15: 916-25.
    • (2013) Nat Cell Biol , vol.15 , pp. 916-925
    • Copley, M.R.1    Babovic, S.2    Benz, C.3    Knapp, D.J.4    Beer, P.A.5    Kent, D.G.6
  • 10
    • 84875933577 scopus 로고    scopus 로고
    • Lin28: Primal regulator of growth and metabolism in stem cells
    • Shyh-Chang N, Daley GQ. Lin28: primal regulator of growth and metabolism in stem cells. Cell Stem Cell 2013; 12: 395-406.
    • (2013) Cell Stem Cell , vol.12 , pp. 395-406
    • Shyh-Chang, N.1    Daley, G.Q.2
  • 12
    • 84874939831 scopus 로고    scopus 로고
    • LIN28/LIN28B: An emerging oncogenic driver in cancer stem cells
    • Zhou J, Ng SB, Chng WJ. LIN28/LIN28B: an emerging oncogenic driver in cancer stem cells. Int J Biochem Cell Biol 2013; 45: 973-8.
    • (2013) Int J Biochem Cell Biol , vol.45 , pp. 973-978
    • Zhou, J.1    Ng, S.B.2    Chng, W.J.3
  • 14
    • 84892610740 scopus 로고    scopus 로고
    • Lin28 induces epithelial-to-mesenchymal transition and stemness via downregulation of let-7a in breast cancer cells
    • Liu Y, Li H, Feng J, Cui X, Huang W, Li Y, et al. Lin28 induces epithelial-to-mesenchymal transition and stemness via downregulation of let-7a in breast cancer cells. PLoS ONE 2013; 8: e83083.
    • (2013) PLoS ONE , vol.8
    • Liu, Y.1    Li, H.2    Feng, J.3    Cui, X.4    Huang, W.5    Li, Y.6
  • 15
    • 84881395046 scopus 로고    scopus 로고
    • LIN28 expression in malignant germ cell tumors downregulates let-7 and increases oncogene levels
    • Murray MJ, Saini HK, Siegler CA, Hanning JE, Barker EM, van Dongen S, et al. LIN28 expression in malignant germ cell tumors downregulates let-7 and increases oncogene levels. Cancer Res 2013; 73: 4872-84.
    • (2013) Cancer Res , vol.73 , pp. 4872-4884
    • Murray, M.J.1    Saini, H.K.2    Siegler, C.A.3    Hanning, J.E.4    Barker, E.M.5    Van Dongen, S.6
  • 17
  • 18
    • 0344063368 scopus 로고    scopus 로고
    • Oct-3/4 is a dose-dependent oncogenic fate determinant
    • Gidekel S, Pizov G, Bergman Y, Pikarsky E. Oct-3/4 is a dose-dependent oncogenic fate determinant. Cancer Cell 2003; 4: 361-70.
    • (2003) Cancer Cell , vol.4 , pp. 361-370
    • Gidekel, S.1    Pizov, G.2    Bergman, Y.3    Pikarsky, E.4
  • 19
    • 84866559462 scopus 로고    scopus 로고
    • Hyaluronan-CD44v3 interaction with Oct4-Sox2-Nanog promotes miR-302 expression leading to self-renewal, clonal formation, and cisplatin resistance in cancer stem cells from head and neck squamous cell carcinoma
    • Bourguignon LY, Wong G, Earle C, Chen L. Hyaluronan-CD44v3 interaction with Oct4-Sox2-Nanog promotes miR-302 expression leading to self-renewal, clonal formation, and cisplatin resistance in cancer stem cells from head and neck squamous cell carcinoma. J Biol Chem 2012; 287: 32800-24.
    • (2012) J Biol Chem , vol.287 , pp. 32800-32824
    • Bourguignon, L.Y.1    Wong, G.2    Earle, C.3    Chen, L.4
  • 20
    • 74949090477 scopus 로고    scopus 로고
    • Recurrent copy number gain of transcription factor SOX2 and corresponding high protein expression in oral squamous cell carcinoma
    • Freier K, Knoepfle K, Flechtenmacher C, Pungs S, Devens F, Toedt G, et al. Recurrent copy number gain of transcription factor SOX2 and corresponding high protein expression in oral squamous cell carcinoma. Genes Chromosomes Cancer 2010; 49: 9-16.
    • (2010) Genes Chromosomes Cancer , vol.49 , pp. 9-16
    • Freier, K.1    Knoepfle, K.2    Flechtenmacher, C.3    Pungs, S.4    Devens, F.5    Toedt, G.6
  • 21
    • 84878610693 scopus 로고    scopus 로고
    • miR145 targets the SOX9/ADAM17axistoinhibit tumor-initiatingcells and IL-6-mediated paracrine effects in head and neck cancer
    • Yu CC, Tsai LL, Wang ML, Yu CH, Lo WL, Chang YC, et al. miR145 targets the SOX9/ADAM17axistoinhibit tumor-initiatingcells and IL-6-mediated paracrine effects in head and neck cancer. Cancer Res 2013; 73: 3425-40.
    • (2013) Cancer Res , vol.73 , pp. 3425-3440
    • Yu, C.C.1    Tsai, L.L.2    Wang, M.L.3    Yu, C.H.4    Lo, W.L.5    Chang, Y.C.6
  • 22
    • 84055207487 scopus 로고    scopus 로고
    • IL-6 promotes head and neck tumor metastasis by inducing epithelial-mesenchymal transition via the JAK-STAT3-SNAIL signaling pathway
    • Yadav A, Kumar B, Datta J, Teknos TN, Kumar P. IL-6 promotes head and neck tumor metastasis by inducing epithelial-mesenchymal transition via the JAK-STAT3-SNAIL signaling pathway. Mol Cancer Res 2011; 9: 1658-67.
    • (2011) Mol Cancer Res , vol.9 , pp. 1658-1667
    • Yadav, A.1    Kumar, B.2    Datta, J.3    Teknos, T.N.4    Kumar, P.5
  • 23
    • 84865556569 scopus 로고    scopus 로고
    • Corneal repair by human corneal keratocyte-reprogrammed iPSCs and amphiphatic carboxymethyl-hexanoyl chitosan hydrogel
    • Chien Y, Liao YW, Liu DM, Lin HL, Chen SJ, Chen HL, et al. Corneal repair by human corneal keratocyte-reprogrammed iPSCs and amphiphatic carboxymethyl-hexanoyl chitosan hydrogel. Biomaterials 2012; 33: 8003-16.
    • (2012) Biomaterials , vol.33 , pp. 8003-8016
    • Chien, Y.1    Liao, Y.W.2    Liu, D.M.3    Lin, H.L.4    Chen, S.J.5    Chen, H.L.6
  • 24
    • 84920724975 scopus 로고    scopus 로고
    • Synergistic effects of carboxymethyl-hexanoyl chitosan, cationic polyurethane-short branch PEI in miR122 gene delivery: Accelerated differentiation of iPSCs into mature hepatocyte-like cells and improved stem cell therapy in a hepatic failure model
    • Chien Y, Chang YL, Li HY, Larsson M, Wu WW, Chien CS, et al. Synergistic effects of carboxymethyl-hexanoyl chitosan, cationic polyurethane-short branch PEI in miR122 gene delivery: accelerated differentiation of iPSCs into mature hepatocyte-like cells and improved stem cell therapy in a hepatic failure model. Acta Biomater 2015; 13: 228-44.
    • (2015) Acta Biomater , vol.13 , pp. 228-244
    • Chien, Y.1    Chang, Y.L.2    Li, H.Y.3    Larsson, M.4    Wu, W.W.5    Chien, C.S.6
  • 26
    • 84890226018 scopus 로고    scopus 로고
    • Epigenetic regulation of the miR142-3p/interleukin-6 circuit in glioblastoma
    • Chiou GY, Chien CS, Wang ML, Chen MT, Yang YP, Yu YL, et al. Epigenetic regulation of the miR142-3p/interleukin-6 circuit in glioblastoma. Mol Cell 2013; 52: 693-706.
    • (2013) Mol Cell , vol.52 , pp. 693-706
    • Chiou, G.Y.1    Chien, C.S.2    Wang, M.L.3    Chen, M.T.4    Yang, Y.P.5    Yu, Y.L.6
  • 27
    • 34548316982 scopus 로고    scopus 로고
    • MicroRNA sponges: Competitive inhibitors of small RNAs in mammalian cells
    • Ebert MS, Neilson JR, Sharp PA. MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells. Nat Methods 2007; 4: 721-6.
    • (2007) Nat Methods , vol.4 , pp. 721-726
    • Ebert, M.S.1    Neilson, J.R.2    Sharp, P.A.3
  • 28
    • 78649648154 scopus 로고    scopus 로고
    • Cucurbitacin I suppressed stem-like property and enhanced radiation-induced apoptosis in head and neck squamous carcinoma-derived CD44(+)ALDH1(+) cells
    • Chen YW, Chen KH, Huang PI, Chen YC, Chiou GY, Lo WL, et al. Cucurbitacin I suppressed stem-like property and enhanced radiation-induced apoptosis in head and neck squamous carcinoma-derived CD44(+)ALDH1(+) cells. Mol Cancer Ther 2010; 9: 2879-92.
    • (2010) Mol Cancer Ther , vol.9 , pp. 2879-2892
    • Chen, Y.W.1    Chen, K.H.2    Huang, P.I.3    Chen, Y.C.4    Chiou, G.Y.5    Lo, W.L.6
  • 30
    • 79952275768 scopus 로고    scopus 로고
    • The ARID family transcription factor bright is required for both hematopoietic stem cell and B lineage development
    • Webb CF, Bryant J, Popowski M, Allred L, Kim D, Harriss J, et al. The ARID family transcription factor bright is required for both hematopoietic stem cell and B lineage development. Mol Cell Biol 2011; 31: 1041-53.
    • (2011) Mol Cell Biol , vol.31 , pp. 1041-1053
    • Webb, C.F.1    Bryant, J.2    Popowski, M.3    Allred, L.4    Kim, D.5    Harriss, J.6
  • 33
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006; 126: 663-76.
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 34
    • 79953058250 scopus 로고    scopus 로고
    • The tumorigenicity of human embryonic and induced pluripotent stem cells
    • Ben-David U, Benvenisty N. The tumorigenicity of human embryonic and induced pluripotent stem cells. Nat Rev Cancer 2011; 11: 268-77.
    • (2011) Nat Rev Cancer , vol.11 , pp. 268-277
    • Ben-David, U.1    Benvenisty, N.2
  • 35
    • 84866849548 scopus 로고    scopus 로고
    • Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer
    • Rudin CM, Durinck S, Stawiski EW, Poirier JT, Modrusan Z, Shames DS, et al. Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer. Nat Genet 2012; 44: 1111-6.
    • (2012) Nat Genet , vol.44 , pp. 1111-1116
    • Rudin, C.M.1    Durinck, S.2    Stawiski, E.W.3    Poirier, J.T.4    Modrusan, Z.5    Shames, D.S.6
  • 36
    • 70350641014 scopus 로고    scopus 로고
    • SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas
    • Bass AJ, Watanabe H, Mermel CH, Yu S, Perner S, Verhaak RG, et al. SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas. Nat Genet 2009; 41: 1238-42.
    • (2009) Nat Genet , vol.41 , pp. 1238-1242
    • Bass, A.J.1    Watanabe, H.2    Mermel, C.H.3    Yu, S.4    Perner, S.5    Verhaak, R.G.6
  • 37
    • 84904668706 scopus 로고    scopus 로고
    • The generation of induced pluripotent stem cells for macular degeneration as a drug screening platform: Identification of curcumin as a protective agent for retinal pigment epithelial cells against oxidative stress
    • Chang YC, Chang WC, Hung KH, Yang DM, Cheng YH, Liao YW, et al. The generation of induced pluripotent stem cells for macular degeneration as a drug screening platform: identification of curcumin as a protective agent for retinal pigment epithelial cells against oxidative stress. Front Aging Neurosci 2014; 6: 191.
    • (2014) Front Aging Neurosci , vol.6 , pp. 191
    • Chang, Y.C.1    Chang, W.C.2    Hung, K.H.3    Yang, D.M.4    Cheng, Y.H.5    Liao, Y.W.6
  • 38
    • 79958265710 scopus 로고    scopus 로고
    • Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast
    • Scheel C, Eaton EN, Li SH, Chaffer CL, Reinhardt F, Kah KJ, et al. Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast. Cell 2011; 145: 926-40.
    • (2011) Cell , vol.145 , pp. 926-940
    • Scheel, C.1    Eaton, E.N.2    Li, S.H.3    Chaffer, C.L.4    Reinhardt, F.5    Kah, K.J.6
  • 39
    • 84905036664 scopus 로고    scopus 로고
    • Cancer: Pathological nuclear reprogramming?
    • Goding CR, Pei D, Lu X. Cancer: pathological nuclear reprogramming? Nat Rev Cancer 2014; 14: 568-73.
    • (2014) Nat Rev Cancer , vol.14 , pp. 568-573
    • Goding, C.R.1    Pei, D.2    Lu, X.3
  • 40
    • 36849078711 scopus 로고    scopus 로고
    • Let-7 regulates self renewal and tumorigenicity of breast cancer cells
    • Yu F, Yao H, Zhu P, Zhang X, Pan Q, Gong C, et al. let-7 regulates self renewal and tumorigenicity of breast cancer cells. Cell 2007; 131: 1109-23.
    • (2007) Cell , vol.131 , pp. 1109-1123
    • Yu, F.1    Yao, H.2    Zhu, P.3    Zhang, X.4    Pan, Q.5    Gong, C.6
  • 41
    • 84891742725 scopus 로고    scopus 로고
    • The let-7/LIN-41 pathway regulates reprogramming to human induced pluripotent stem cells by controlling expression of prodifferentiation genes
    • Worringer KA, Rand TA, Hayashi Y, Sami S, Takahashi K, Tanabe K, et al. The let-7/LIN-41 pathway regulates reprogramming to human induced pluripotent stem cells by controlling expression of prodifferentiation genes. Cell Stem Cell 2014; 14: 40-52.
    • (2014) Cell Stem Cell , vol.14 , pp. 40-52
    • Worringer, K.A.1    Rand, T.A.2    Hayashi, Y.3    Sami, S.4    Takahashi, K.5    Tanabe, K.6
  • 43
    • 63049090064 scopus 로고    scopus 로고
    • A fresh look at iPS cells
    • Yamanaka S. A fresh look at iPS cells. Cell 2009; 137: 13-7.
    • (2009) Cell , vol.137 , pp. 13-17
    • Yamanaka, S.1
  • 44
    • 77955699082 scopus 로고    scopus 로고
    • Octamer 4 (Oct4) mediates chemotherapeutic drug resistance in liver cancer cells through a potential Oct4-AKT-ATP-binding cassette G2 pathway
    • Wang XQ, Ongkeko WM, Chen L, Yang ZF, Lu P, Chen KK, et al. Octamer 4 (Oct4) mediates chemotherapeutic drug resistance in liver cancer cells through a potential Oct4-AKT-ATP-binding cassette G2 pathway. Hepatology 2010; 52: 528-39.
    • (2010) Hepatology , vol.52 , pp. 528-539
    • Wang, X.Q.1    Ongkeko, W.M.2    Chen, L.3    Yang, Z.F.4    Lu, P.5    Chen, K.K.6
  • 45
    • 33749026967 scopus 로고    scopus 로고
    • ARID3B induces malignant transformation of mouse embryonic fibroblasts and is strongly associated with malignant neuroblastoma
    • Kobayashi K, Era T, Takebe A, Jakt LM, Nishikawa S. ARID3B induces malignant transformation of mouse embryonic fibroblasts and is strongly associated with malignant neuroblastoma. Cancer Res 2006; 66: 8331-6.
    • (2006) Cancer Res , vol.66 , pp. 8331-8336
    • Kobayashi, K.1    Era, T.2    Takebe, A.3    Jakt, L.M.4    Nishikawa, S.5
  • 46
    • 79955137548 scopus 로고    scopus 로고
    • Apical ectodermal ridge morphogenesis in limb development is controlled by Arid3b-mediated regulation of cell movements
    • Casanova JC, Uribe V, Badia-Careaga C, Giovinazzo G, Torres M, Sanz-Ezquerro JJ. Apical ectodermal ridge morphogenesis in limb development is controlled by Arid3b-mediated regulation of cell movements. Development 2011; 138: 1195-205.
    • (2011) Development , vol.138 , pp. 1195-1205
    • Casanova, J.C.1    Uribe, V.2    Badia-Careaga, C.3    Giovinazzo, G.4    Torres, M.5    Sanz-Ezquerro, J.J.6
  • 47
    • 33646048037 scopus 로고    scopus 로고
    • Microarray analysis of PDGFR alpha+ populations in ES cell differentiation culture identifies genes involved indifferentiation of mesoderm and mesenchyme including ARID3b that is essential for development of embryonic mesenchymal cells
    • Takebe A, Era T, Okada M, Martin Jakt L, Kuroda Y, Nishikawa S. Microarray analysis of PDGFR alpha+ populations in ES cell differentiation culture identifies genes involved indifferentiation of mesoderm and mesenchyme including ARID3b that is essential for development of embryonic mesenchymal cells. Dev Biol 2006; 293: 25-37.
    • (2006) Dev Biol , vol.293 , pp. 25-37
    • Takebe, A.1    Era, T.2    Okada, M.3    Martin Jakt, L.4    Kuroda, Y.5    Nishikawa, S.6
  • 48
    • 84878223532 scopus 로고    scopus 로고
    • Epigenetic regulation of the neuroblastoma genes, Arid3b and Mycn
    • Kobayashi K, Jakt LM, Nishikawa SI. Epigenetic regulation of the neuroblastoma genes, Arid3b and Mycn. Oncogene 2013; 32: 2640-8.
    • (2013) Oncogene , vol.32 , pp. 2640-2648
    • Kobayashi, K.1    Jakt, L.M.2    Nishikawa, S.I.3
  • 49
    • 84899638378 scopus 로고    scopus 로고
    • Differential expression of ARID3B in normal adult tissue and carcinomas
    • Samyesudhas SJ, Roy L, Cowden Dahl KD Differential expression of ARID3B in normal adult tissue and carcinomas. Gene 2014; 543: 174-80.
    • (2014) Gene , vol.543 , pp. 174-180
    • Samyesudhas, S.J.1    Roy, L.2    Cowden Dahl, K.D.3
  • 50
    • 84883377444 scopus 로고    scopus 로고
    • Nuclear reprogramming and the cancer genome
    • Nuclear reprogramming and the cancer genome. Nat Genet 2013; 45: 963.
    • (2013) Nat Genet , vol.45 , pp. 963


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