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Volumn 45, Issue 12, 2015, Pages 2557-2569

Expression quantitative trait loci (eQTLs) in microRNA genes are enriched for schizophrenia and bipolar disorder association signals

Author keywords

Bipolar disorder; eQTLs; GWAS; miRNAs; schizophrenia

Indexed keywords

MICRORNA;

EID: 84938651346     PISSN: 00332917     EISSN: 14698978     Source Type: Journal    
DOI: 10.1017/S0033291715000483     Document Type: Article
Times cited : (13)

References (92)
  • 1
    • 84878799611 scopus 로고    scopus 로고
    • Predicting functional effect of human missense mutations using polyphen-2
    • 7.20.1-7.20.41
    • Adzhubei I, Jordan DM, Sunyaev SR. (2013). Predicting functional effect of human missense mutations using PolyPhen-2. Current Protocols in Human Genetics, 76, 7.20.1-7.20.41
    • (2013) Current Protocols in Human Genetics , vol.76
    • Adzhubei, I.1    Jordan, D.M.2    Sunyaev, S.R.3
  • 4
    • 72149086111 scopus 로고    scopus 로고
    • A coordinated local translational control point at the synapse involving relief from silencing and mov10 degradation
    • Banerjee S, Neveu P, Kosik KS. (2009). A coordinated local translational control point at the synapse involving relief from silencing and MOV10 degradation. Neuron 64, 871-884
    • (2009) Neuron , vol.64 , pp. 871-884
    • Banerjee, S.1    Neveu, P.2    Kosik, K.S.3
  • 9
    • 77955963884 scopus 로고    scopus 로고
    • Comprehensive modeling of microrna targets predicts functional non-conserved and non-canonical sites
    • Betel D, Koppal A, Agius P, Sander C, Leslie C. (2010). Comprehensive modeling of microRNA targets predicts functional non-conserved and non-canonical sites. Genome Biology 11, R90
    • (2010) Genome Biology , vol.11 , pp. R90
    • Betel, D.1    Koppal, A.2    Agius, P.3    Sander, C.4    Leslie, C.5
  • 11
  • 13
    • 53449093828 scopus 로고    scopus 로고
    • G-protein-coupled receptors: From classical modes of modulation to allosteric mechanisms
    • Bridges TM, Lindsley CW. (2008). G-protein-coupled receptors: from classical modes of modulation to allosteric mechanisms. ACS Chemical Biology 3, 530-541
    • (2008) ACS Chemical Biology , vol.3 , pp. 530-541
    • Bridges, T.M.1    Lindsley, C.W.2
  • 16
    • 84877113728 scopus 로고    scopus 로고
    • Neuregulin-1 signalling and antipsychotic treatment: Potential therapeutic targets in a schizophrenia candidate signalling pathway
    • Deng C, Pan B, Engel M, Huang XF. (2013). Neuregulin-1 signalling and antipsychotic treatment: potential therapeutic targets in a schizophrenia candidate signalling pathway. Psychopharmacology (Berlin) 226, 201-215
    • (2013) Psychopharmacology (Berlin , vol.226 , pp. 201-215
    • Deng, C.1    Pan, B.2    Engel, M.3    Huang, X.F.4
  • 17
    • 0036123111 scopus 로고    scopus 로고
    • Computational detection and location of transcription start sites in mammalian genomic DNA
    • Down TA, Hubbard TJ. (2002). Computational detection and location of transcription start sites in mammalian genomic DNA. Genome Research 12, 458-461
    • (2002) Genome Research , vol.12 , pp. 458-461
    • Down, T.A.1    Hubbard, T.J.2
  • 18
    • 79959805164 scopus 로고    scopus 로고
    • Mirwalk-database: Prediction of possible mirna binding sites by' walking' the genes of three genomes
    • Dweep H, Sticht C, Pandey P, Gretz N. (2011). miRWalk-database: prediction of possible miRNA binding sites by' walking' the genes of three genomes. Journal of Biomedical Informatics 44, 839-847
    • (2011) Journal of Biomedical Informatics , vol.44 , pp. 839-847
    • Dweep, H.1    Sticht, C.2    Pandey, P.3    Gretz, N.4
  • 20
    • 38349169664 scopus 로고    scopus 로고
    • Mechanisms of post-Transcriptional regulation by micrornas: Are the answers in sight
    • Filipowicz W, Bhattacharyya SN, Sonenberg N. (2008). Mechanisms of post-Transcriptional regulation by microRNAs: are the answers in sight? Nature Reviews Genetics 9, 102-114
    • (2008) Nature Reviews Genetics , vol.9 , pp. 102-114
    • Filipowicz, W.1    Bhattacharyya, S.N.2    Sonenberg, N.3
  • 23
    • 84908043370 scopus 로고    scopus 로고
    • Increased g protein-coupled receptor kinase (grk) expression in the anterior cingulate cortex in schizophrenia
    • Funk AJ, Haroutunian V, Meador-Woodruff JH, McCullumsmith RE. (2014). Increased G protein-coupled receptor kinase (GRK) expression in the anterior cingulate cortex in schizophrenia. Schizophrenia Research 159, 130-135
    • (2014) Schizophrenia Research , vol.159 , pp. 130-135
    • Funk, A.J.1    Haroutunian, V.2    Meador-Woodruff, J.H.3    McCullumsmith, R.E.4
  • 27
    • 85019507551 scopus 로고    scopus 로고
    • Microrna and posttranscriptional dysregulation in psychiatry
    • Geaghan M, Cairns MJ. (2014). MicroRNA and Posttranscriptional Dysregulation in Psychiatry. Biological Psychiatry
    • (2014) Biological Psychiatry
    • Geaghan, M.1    Cairns, M.J.2
  • 29
    • 84864383515 scopus 로고    scopus 로고
    • Intronic micrornas: A crossroad in gene regulation
    • Gromak N. (2012). Intronic microRNAs: a crossroad in gene regulation. Biochemical Society Transactions 40, 759-761
    • (2012) Biochemical Society Transactions , vol.40 , pp. 759-761
    • Gromak, N.1
  • 30
    • 77949426688 scopus 로고    scopus 로고
    • A novel microrna and transcription factor mediated regulatory network in schizophrenia
    • Guo AY, Sun J, Jia P, Zhao Z. (2010). A Novel microRNA and transcription factor mediated regulatory network in schizophrenia. BMC System Biology 4, 10
    • (2010) BMC System Biology , vol.4 , pp. 10
    • Guo, A.Y.1    Sun, J.2    Jia, P.3    Zhao, Z.4
  • 32
    • 0036382428 scopus 로고    scopus 로고
    • Infection, treatment and immune response in patients with bipolar disorder versus patients with major depression, schizophrenia or healthy controls
    • Hinze-Selch D. (2002). Infection, treatment and immune response in patients with bipolar disorder versus patients with major depression, schizophrenia or healthy controls. Bipolar Disorders 4 (Suppl. 1), 81-83
    • (2002) Bipolar Disorders , vol.4 , pp. 81-83
    • Hinze-Selch, D.1
  • 35
    • 84906270754 scopus 로고    scopus 로고
    • Top associated snps in prostate cancer are significantly enriched in cis-expression quantitative trait loci and at transcription factor binding sites
    • Jiang J, Jia P, Shen B, Zhao Z. (2014). Top associated SNPs in prostate cancer are significantly enriched in cis-expression quantitative trait loci and at transcription factor binding sites. Oncotarget 5, 6168-6177
    • (2014) Oncotarget , vol.5 , pp. 6168-6177
    • Jiang, J.1    Jia, P.2    Shen, B.3    Zhao, Z.4
  • 40
    • 72449182114 scopus 로고    scopus 로고
    • The stanley neuropathology consortium integrative database: A novel, web-based tool for exploring neuropathological markers in psychiatric disorders and the biological processes associated with abnormalities of those markers
    • Kim S, Webster MJ. (2010). The stanley neuropathology consortium integrative database: a novel, web-based tool for exploring neuropathological markers in psychiatric disorders and the biological processes associated with abnormalities of those markers. Neuropsychopharmacology 35, 473-482
    • (2010) Neuropsychopharmacology , vol.35 , pp. 473-482
    • Kim, S.1    Webster, M.J.2
  • 41
    • 84891818318 scopus 로고    scopus 로고
    • Mirbase: Annotating high confidence micrornas using deep sequencing data
    • Kozomara A, Griffiths-Jones S. (2014). miRBase: annotating high confidence microRNAs using deep sequencing data. Nucleic Acids Research 42, D68-D73
    • (2014) Nucleic Acids Research , vol.42 , pp. D68-D73
    • Kozomara, A.1    Griffiths-Jones, S.2
  • 43
    • 84871270974 scopus 로고    scopus 로고
    • Validation of schizophrenia-Associated genes csmd1, c10orf26, cacna1c and tcf4 as MIR-137 targets
    • Kwon E, Wang W, Tsai LH. (2013). Validation of schizophrenia-Associated genes CSMD1, C10orf26, CACNA1C and TCF4 as miR-137 targets. Molecular Psychiatry 18, 11-12
    • (2013) Molecular Psychiatry , vol.18 , pp. 11-12
    • Kwon, E.1    Wang, W.2    Tsai, L.H.3
  • 45
    • 84908450350 scopus 로고    scopus 로고
    • Investigating the functional implications of reinforcing feedback loops in transcriptional regulatory networks
    • Li Y, Liang C, Easterbrook S, Luo J, Zhang Z. (2014). Investigating the functional implications of reinforcing feedback loops in transcriptional regulatory networks. Molecular Biosystems 10, 3238-3248
    • (2014) Molecular Biosystems , vol.10 , pp. 3238-3248
    • Li, Y.1    Liang, C.2    Easterbrook, S.3    Luo, J.4    Zhang, Z.5
  • 47
    • 76749102887 scopus 로고    scopus 로고
    • E2f1-inducible microrna 449a/b suppresses cell proliferation and promotes apoptosis
    • Lize M, Pilarski S, Dobbelstein M. (2010). E2F1-inducible microRNA 449a/b suppresses cell proliferation and promotes apoptosis. Cell Death and Differentiation 17, 452-458
    • (2010) Cell Death and Differentiation , vol.17 , pp. 452-458
    • Lize, M.1    Pilarski, S.2    Dobbelstein, M.3
  • 50
    • 55249091422 scopus 로고    scopus 로고
    • Schizophrenia: A concise overview of incidence, prevalence, and mortality
    • McGrath J, Saha S, Chant D, Welham J. (2008). Schizophrenia: a concise overview of incidence, prevalence, and mortality. Epidemiological Reviews 30, 67-76
    • (2008) Epidemiological Reviews , vol.30 , pp. 67-76
    • McGrath, J.1    Saha, S.2    Chant, D.3    Welham, J.4
  • 53
    • 84876180068 scopus 로고    scopus 로고
    • Chronological changes in microrna expression in the developing human brain
    • Moreau MP, Bruse SE, Jornsten R, Liu Y, Brzustowicz LM. (2013). Chronological changes in microRNA expression in the developing human brain. PLoS One 8, e60480
    • (2013) PLoS One , vol.8 , pp. e60480
    • Moreau, M.P.1    Bruse, S.E.2    Jornsten, R.3    Liu, Y.4    Brzustowicz, L.M.5
  • 54
    • 33847013040 scopus 로고    scopus 로고
    • In vivo administration of epidermal growth factor and its homologue attenuates developmental maturation of functional excitatory synapses in cortical gabaergic neurons
    • Nagano T, Namba H, Abe Y, Aoki H, Takei N, Nawa H. (2007). In vivo administration of epidermal growth factor and its homologue attenuates developmental maturation of functional excitatory synapses in cortical GABAergic neurons. European Journal of Neuroscience 25, 380-390
    • (2007) European Journal of Neuroscience , vol.25 , pp. 380-390
    • Nagano, T.1    Namba, H.2    Abe, Y.3    Aoki, H.4    Takei, N.5    Nawa, H.6
  • 55
    • 84920591399 scopus 로고    scopus 로고
    • Drugs targeting snprs35753505 of the nrg1 gene may prevent the association of neurological disorder schizophrenia in a pakistani population
    • Nawaz R, Asif H, Khan A, Ishtiaq H, Shad F, Siddiqui S. (2014). Drugs targeting SNPrs35753505 of the NRG1 gene may prevent the association of neurological disorder schizophrenia in a Pakistani population. CNS Neurolologial Disorders and Drug Targets 13, 1604-1614
    • (2014) CNS Neurolologial Disorders and Drug Targets , vol.13 , pp. 1604-1614
    • Nawaz, R.1    Asif, H.2    Khan, A.3    Ishtiaq, H.4    Shad, F.5    Siddiqui, S.6
  • 56
    • 77951439152 scopus 로고    scopus 로고
    • Trait-Associated snps are more likely to be eqtls: Annotation to enhance discovery from gwas
    • Nicolae DL, Gamazon E, Zhang W, Duan S, Dolan ME, Cox NJ. (2010). Trait-Associated SNPs are more likely to be eQTLs: annotation to enhance discovery from GWAS. PLoS Genetics 6, e1000888
    • (2010) PLoS Genetics , vol.6 , pp. e1000888
    • Nicolae, D.L.1    Gamazon, E.2    Zhang, W.3    Duan, S.4    Dolan, M.E.5    Cox, N.J.6
  • 57
    • 70350217340 scopus 로고    scopus 로고
    • Micrornas show mutually exclusive expression patterns in the brain of adult male rats
    • Olsen L, Klausen M, Helboe L, Nielsen FC, Werge T. (2009). MicroRNAs show mutually exclusive expression patterns in the brain of adult male rats. PLoS ONE 4, e7225
    • (2009) PLoS ONE , vol.4 , pp. e7225
    • Olsen, L.1    Klausen, M.2    Helboe, L.3    Nielsen, F.C.4    Werge, T.5
  • 63
    • 84928649426 scopus 로고    scopus 로고
    • Integrating microrna target predictions for the discovery of gene regulatory networks: A semi-supervised ensemble learning approach
    • Pio G, Malerba D, D'Elia D, Ceci M. (2014). Integrating microRNA target predictions for the discovery of gene regulatory networks: a semi-supervised ensemble learning approach. BMC Bioinformatics 15 (Suppl. 1), S4
    • (2014) BMC Bioinformatics , vol.15 , pp. S4
    • Pio, G.1    Malerba, D.2    D'elia, D.3    Ceci, M.4
  • 64
    • 80053384370 scopus 로고    scopus 로고
    • Genome-wide association study identifies five new schizophrenia loci
    • Psychiatric Genetics Consortium (PGC
    • Psychiatric Genetics Consortium (PGC) (2011). Genome-wide association study identifies five new schizophrenia loci. Nature Genetics 43, 969-976
    • (2011) Nature Genetics , vol.43 , pp. 969-976
  • 68
    • 4644237189 scopus 로고    scopus 로고
    • Fast and effective prediction of microrna/target duplexes
    • Rehmsmeier M, Steffen P, Hochsmann M, Giegerich R. (2004). Fast and effective prediction of microRNA/target duplexes. RNA 10, 1507-1517
    • (2004) RNA , vol.10 , pp. 1507-1517
    • Rehmsmeier, M.1    Steffen, P.2    Hochsmann, M.3    Giegerich, R.4
  • 74
    • 78650511568 scopus 로고    scopus 로고
    • Upregulation of dicer and microrna expression in the dorsolateral prefrontal cortex brodmann area 46 in schizophrenia
    • Santarelli DM, Beveridge NJ, Tooney PA, Cairns MJ. (2011). Upregulation of dicer and microRNA expression in the dorsolateral prefrontal cortex Brodmann area 46 in schizophrenia. Biological Psychiatry 69, 180-187
    • (2011) Biological Psychiatry , vol.69 , pp. 180-187
    • Santarelli, D.M.1    Beveridge, N.J.2    Tooney, P.A.3    Cairns, M.J.4
  • 75
    • 84861153094 scopus 로고    scopus 로고
    • Matrix eqtl: Ultra fast eqtl analysis via large matrix operations
    • Shabalin AA. (2012). Matrix eQTL: ultra fast eQTL analysis via large matrix operations. Bioinformatics 28, 1353-1358
    • (2012) Bioinformatics , vol.28 , pp. 1353-1358
    • Shabalin, A.A.1
  • 76
    • 84906935783 scopus 로고    scopus 로고
    • Regulation of microrna function in somatic stem cell proliferation and differentiation
    • Shenoy A, Blelloch RH. (2014). Regulation of microRNA function in somatic stem cell proliferation and differentiation. Nature Reviews Molecular Cell Biology 15, 565-576
    • (2014) Nature Reviews Molecular Cell Biology , vol.15 , pp. 565-576
    • Shenoy, A.1    Blelloch, R.H.2
  • 80
    • 77950348609 scopus 로고    scopus 로고
    • Genomewide dissection of microrna functions and cotargeting networks using gene set signatures
    • Tsang JS, Ebert MS, van Oudenaarden A. (2010). Genomewide dissection of microRNA functions and cotargeting networks using gene set signatures. Molecular Cell 38, 140-153
    • (2010) Molecular Cell , vol.38 , pp. 140-153
    • Tsang, J.S.1    Ebert, M.S.2    Van Oudenaarden, A.3
  • 82
    • 84881308928 scopus 로고    scopus 로고
    • Mirmap web: Comprehensive microrna target prediction online
    • Vejnar CE, Blum M, Zdobnov EM. (2013). miRmap web: comprehensive microRNA target prediction online. Nucleic Acids Research 41, W165-W168
    • (2013) Nucleic Acids Research , vol.41 , pp. W165-W168
    • Vejnar, C.E.1    Blum, M.2    Zdobnov, E.M.3
  • 83
    • 38849145861 scopus 로고    scopus 로고
    • Prediction of both conserved and nonconserved microrna targets in animals
    • Wang X, El Naqa IM. (2008). Prediction of both conserved and nonconserved microRNA targets in animals. Bioinformatics 24, 325-332
    • (2008) Bioinformatics , vol.24 , pp. 325-332
    • Wang, X.1    El Naqa, I.M.2
  • 85
  • 86
    • 34249294856 scopus 로고    scopus 로고
    • Energizing mirna research: A review of the role of mirnas in lipid metabolism, with a prediction that MIR-103/107 regulates human metabolic pathways
    • Wilfred BR, Wang WX, Nelson PT. (2007). Energizing miRNA research: a review of the role of miRNAs in lipid metabolism, with a prediction that miR-103/107 regulates human metabolic pathways. Molecular Genetics and Metabolism 91, 209-217
    • (2007) Molecular Genetics and Metabolism , vol.91 , pp. 209-217
    • Wilfred, B.R.1    Wang, W.X.2    Nelson, P.T.3
  • 88
    • 67849101182 scopus 로고    scopus 로고
    • Snpinfo: Integrating gwas and candidate gene information into functional snp selection for genetic association studies
    • Xu Z, Taylor JA. (2009). SNPinfo: integrating GWAS and candidate gene information into functional SNP selection for genetic association studies. Nucleic Acids Research 37, W600-W605
    • (2009) Nucleic Acids Research , vol.37 , pp. W600-W605
    • Xu, Z.1    Taylor, J.A.2
  • 89
    • 84927128873 scopus 로고    scopus 로고
    • Ensemble learning can significantly improve human microrna target prediction
    • Yu S, Kim J, Min H, Yoon S. (2014). Ensemble learning can significantly improve human microRNA target prediction. Methods 69, 220-229
    • (2014) Methods , vol.69 , pp. 220-229
    • Yu, S.1    Kim, J.2    Min, H.3    Yoon, S.4
  • 91
    • 77954504259 scopus 로고    scopus 로고
    • Comparison and integration of target prediction algorithms for microrna studies
    • Zhang Y, Verbeek FJ. (2010). Comparison and integration of target prediction algorithms for microRNA studies. Journal of Integrative Bioinformatics 7(3), 127
    • (2010) Journal of Integrative Bioinformatics , vol.7 , Issue.3 , pp. 127
    • Zhang, Y.1    Verbeek, F.J.2
  • 92
    • 64049095014 scopus 로고    scopus 로고
    • A feedback regulatory loop involving microrna-9 and nuclear receptor tlx in neural stem cell fate determination
    • Zhao C, Sun G, Li S, Shi Y. (2009). A feedback regulatory loop involving microRNA-9 and nuclear receptor TLX in neural stem cell fate determination. Nature Structural and Molecular Biology 16, 365-371
    • (2009) Nature Structural and Molecular Biology , vol.16 , pp. 365-371
    • Zhao, C.1    Sun, G.2    Li, S.3    Shi, Y.4


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