Arf6 regulates tumour angiogenesis and growth through HGF-induced endothelial β1 integrin recycling

Nature Communications

Volumn 6, Issue , 2015, Pages

  Hongu, Tsunaki ^a   Funakoshi, Yuji ^a   Fukuhara, Shigetomo ^b   Suzuki, Teruhiko ^a,d   Sakimoto, Susumu ^c,e   Takakura, Nobuyuki ^c   Ema, Masatsugu ^a,f   Takahashi, Satoru ^a   Itoh, Susumu ^a,g   Kato, Mitsuyasu ^a   Hasegawa, Hiroshi ^a   Mochizuki, Naoki ^b   Kanaho, Yasunori ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^c OSAKA UNIVERSITY   (Japan)

^d TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^e SCRIPPS RESEARCH INSTITUTE   (United States)

^f SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

^g SHOWA PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE RIBOSYLATION FACTOR 6; BETA1 INTEGRIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; SCATTER FACTOR; ADENOSINE DIPHOSPHATE RIBOSYLATION FACTOR; ADP-RIBOSYLATION FACTOR 6; CELL RECEPTOR; HGF PROTEIN, MOUSE; MESSENGER RNA; PHOSPHATIDYLINOSITOL RECEPTORS; SCATTER FACTOR RECEPTOR;

CELLS AND CELL COMPONENTS; ENZYME ACTIVITY; GROWTH; INHIBITION; PHARMACEUTICAL INDUSTRY; RECYCLING; RODENT; SIGNALING; TUMOR;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIANGIOGENIC ACTIVITY; ARTICLE; CANCER INHIBITION; CELL SPREADING; CONTROLLED STUDY; EMBRYO; ENDOTHELIUM CELL; ENZYME INHIBITION; FEMALE; FOCAL ADHESION; GENE DELETION; GROWTH REGULATION; HUMAN; HUMAN CELL; KNOCKOUT MOUSE; LEWIS CARCINOMA; MALE; MELANOMA B16; MOUSE; NONHUMAN; RECYCLING; SIGNAL TRANSDUCTION; TARGET CELL; TUMOR GROWTH; TUMOR VASCULARIZATION; ANIMAL; ANTAGONISTS AND INHIBITORS; CANCER TRANSPLANTATION; CELL MEMBRANE; CELL MIGRATION ASSAY; ENZYME LINKED IMMUNOSORBENT ASSAY; EXPERIMENTAL MELANOMA; GENETICS; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; METABOLISM; NEOVASCULARIZATION (PATHOLOGY); RETINA; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSGENIC MOUSE; TUMOR CELL LINE; VASCULARIZATION; WESTERN BLOTTING;

MUS;

ADP-RIBOSYLATION FACTORS; ANIMALS; ANTIGENS, CD29; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL MEMBRANE; CELL MIGRATION ASSAYS; ENDOTHELIAL CELLS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FOCAL ADHESIONS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HEPATOCYTE GROWTH FACTOR; IMMUNOHISTOCHEMISTRY; IN VITRO TECHNIQUES; MELANOMA, EXPERIMENTAL; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; NEOPLASM TRANSPLANTATION; NEOVASCULARIZATION, PATHOLOGIC; PROTO-ONCOGENE PROTEINS C-MET; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RETINA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 84938634250     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms8925     Document Type: Article

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