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Volumn 29, Issue 38, 2010, Pages 5286-5298

Cell delivery of Met docking site peptides inhibit angiogenesis and vascular tumor growth

Author keywords

angiogenesis; Antennapedia; cancer; cell penetrating peptides; Met; Tat

Indexed keywords

5 (2,6 DICHLOROBENZYLSULFONYL) 3 [3,5 DIMETHYL 4 [2 (1 PYRROLIDINYLMETHYL) 1 PYRROLIDINYLCARBONYL] 1H PYRROL 2 YLMETHYLENE] 1,3 DIHYDRO 2H INDOL 2 ONE; ANTENNAPEDIA PROTEIN; SCATTER FACTOR; SCATTER FACTOR RECEPTOR; SYNTHETIC PEPTIDE; TRANSACTIVATOR PROTEIN; GROWTH FACTOR RECEPTOR; MET PROTEIN, HUMAN;

EID: 77957119630     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2010.267     Document Type: Article
Times cited : (21)

References (69)
  • 1
    • 34347234200 scopus 로고    scopus 로고
    • The chemoinvasion assay: A method to assess tumor and endothelial cell invasion and its modulation
    • Albini A, Benelli R. (2007). The chemoinvasion assay: a method to assess tumor and endothelial cell invasion and its modulation. Nat Protocol 2: 504-511.
    • (2007) Nat Protocol , vol.2 , pp. 504-511
    • Albini, A.1    Benelli, R.2
  • 2
    • 0027981273 scopus 로고
    • Angiogenic potential in vivo by Kaposi's sarcoma cell-free supernatants and HIV-1 tat product: Inhibition of KS-like lesions by tissue inhibitor of metalloproteinase-2
    • Albini A, Fontanini G, Masiello L, Tacchetti C, Bigini D, Luzzi P et al. (1994). Angiogenic potential in vivo by Kaposi's sarcoma cell-free supernatants and HIV-1 tat product: inhibition of KS-like lesions by tissue inhibitor of metalloproteinase-2. AIDS 8: 1237-1244.
    • (1994) AIDS , vol.8 , pp. 1237-1244
    • Albini, A.1    Fontanini, G.2    Masiello, L.3    Tacchetti, C.4    Bigini, D.5    Luzzi, P.6
  • 4
    • 0035890541 scopus 로고    scopus 로고
    • Inhibition of angiogenesis-driven Kaposi's sarcoma tumor growth in nude mice by oral N-acetylcysteine
    • Albini A, Morini M, D'Agostini F, Ferrari N, Campelli F, Arena G et al. (2001). Inhibition of angiogenesis-driven Kaposi's sarcoma tumor growth in nude mice by oral N-acetylcysteine. Cancer Res 61: 8171-8178.
    • (2001) Cancer Res , vol.61 , pp. 8171-8178
    • Albini, A.1    Morini, M.2    D'Agostini, F.3    Ferrari, N.4    Campelli, F.5    Arena, G.6
  • 5
    • 8244221004 scopus 로고    scopus 로고
    • The beta-core fragment of human chorionic gonadotrophin inhibits growth of Kaposi's sarcoma-derived cells and a new immortalized Kaposi's sarcoma cell line
    • Albini A, Paglieri I, Orengo G, Carlone S, Aluigi MG, DeMarchi R et al. (1997). The beta-core fragment of human chorionic gonadotrophin inhibits growth of Kaposi's sarcoma-derived cells and a new immortalized Kaposi's sarcoma cell line. AIDS 11: 713-721.
    • (1997) AIDS , vol.11 , pp. 713-721
    • Albini, A.1    Paglieri, I.2    Orengo, G.3    Carlone, S.4    Aluigi, M.G.5    Demarchi, R.6
  • 6
    • 0031005766 scopus 로고    scopus 로고
    • A natural hepatocyte growth factor/scatter factor autocrine loop in myoblast cells and the effect of the constitutive Met kinase activation on myogenic differentiation
    • Anastasi S, Giordano S, Sthandier O, Gambarotta G, Maione R, Comoglio P et al. (1997). A natural hepatocyte growth factor/scatter factor autocrine loop in myoblast cells and the effect of the constitutive Met kinase activation on myogenic differentiation. J Cell Biol 137: 1057-1068.
    • (1997) J Cell Biol , vol.137 , pp. 1057-1068
    • Anastasi, S.1    Giordano, S.2    Sthandier, O.3    Gambarotta, G.4    Maione, R.5    Comoglio, P.6
  • 7
    • 0032832192 scopus 로고    scopus 로고
    • A peptide representing the carboxyl-terminal tail of the met receptor inhibits kinase activity and invasive growth
    • Bardelli A, Longati P, Williams TA, Benvenuti S, Comoglio PM. (1999). A peptide representing the carboxyl-terminal tail of the met receptor inhibits kinase activity and invasive growth. J Biol Chem 274: 29274-29281.
    • (1999) J Biol Chem , vol.274 , pp. 29274-29281
    • Bardelli, A.1    Longati, P.2    Williams, T.A.3    Benvenuti, S.4    Comoglio, P.M.5
  • 8
    • 23044500839 scopus 로고    scopus 로고
    • Agonist Met antibodies define the signalling threshold required for a full mitogenic and invasive program of Kaposi's sarcoma cells
    • Bardelli C, Sala M, Cavallazzi U, Prat M. (2005). Agonist Met antibodies define the signalling threshold required for a full mitogenic and invasive program of Kaposi's sarcoma cells. Biochem Biophys Res Commun 334: 1172-1179.
    • (2005) Biochem Biophys Res Commun , vol.334 , pp. 1172-1179
    • Bardelli, C.1    Sala, M.2    Cavallazzi, U.3    Prat, M.4
  • 9
    • 3142691273 scopus 로고    scopus 로고
    • The Met kinase inhibitor SU11274 exhibits a selective inhibition pattern toward different receptor mutated variants
    • Berthou S, Aebersold DM, Schmidt LS, Stroka D, Heigl C, Streit B et al. (2004). The Met kinase inhibitor SU11274 exhibits a selective inhibition pattern toward different receptor mutated variants. Oncogene 23: 5387-5393.
    • (2004) Oncogene , vol.23 , pp. 5387-5393
    • Berthou, S.1    Aebersold, D.M.2    Schmidt, L.S.3    Stroka, D.4    Heigl, C.5    Streit, B.6
  • 11
    • 0029134104 scopus 로고
    • Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud
    • Bladt F, Riethmacher D, Isenmann S, Aguzzi A, Birchmeier C. (1995). Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud. Nature 376: 768-771.
    • (1995) Nature , vol.376 , pp. 768-771
    • Bladt, F.1    Riethmacher, D.2    Isenmann, S.3    Aguzzi, A.4    Birchmeier, C.5
  • 12
    • 33746504571 scopus 로고    scopus 로고
    • Invasive growth: A MET-driven genetic programme for cancer and stem cells
    • Boccaccio C, Comoglio PM. (2006). Invasive growth: a MET-driven genetic programme for cancer and stem cells. Nat Rev Cancer 6: 637-645.
    • (2006) Nat Rev Cancer , vol.6 , pp. 637-645
    • Boccaccio, C.1    Comoglio, P.M.2
  • 13
    • 0026722243 scopus 로고
    • Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth
    • Bussolino F, Di Renzo MF, Ziche M, Bocchietto E, Olivero M, Naldini L et al. (1992). Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth. J Cell Biol 119: 629-641.
    • (1992) J Cell Biol , vol.119 , pp. 629-641
    • Bussolino, F.1    Di Renzo, M.F.2    Ziche, M.3    Bocchietto, E.4    Olivero, M.5    Naldini, L.6
  • 14
    • 0035912757 scopus 로고    scopus 로고
    • Neutralizing monoclonal antibodies to hepatocyte growth factor/scatter factor (HGF/SF) display antitumor activity in animal models
    • Cao B, Su Y, Oskarsson M, Zhao P, Kort EJ, Fisher RJ et al. (2001). Neutralizing monoclonal antibodies to hepatocyte growth factor/scatter factor (HGF/SF) display antitumor activity in animal models. Proc Natl Acad Sci USA 98: 7443-7448.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 7443-7448
    • Cao, B.1    Su, Y.2    Oskarsson, M.3    Zhao, P.4    Kort, E.J.5    Fisher, R.J.6
  • 15
    • 33646407806 scopus 로고    scopus 로고
    • Hepatocyte growth factor is a lymphangiogenic factor with an indirect mechanism of action
    • Cao R, Bjorndahl MA, Gallego MI, Chen S, Religa P, Hansen AJ et al. (2006). Hepatocyte growth factor is a lymphangiogenic factor with an indirect mechanism of action. Blood 107: 3531-3536.
    • (2006) Blood , vol.107 , pp. 3531-3536
    • Cao, R.1    Bjorndahl, M.A.2    Gallego, M.I.3    Chen, S.4    Religa, P.5    Hansen, A.J.6
  • 16
    • 0034648765 scopus 로고    scopus 로고
    • Angiogenesis in cancer and other diseases
    • Carmeliet P, Jain RK. (2000). Angiogenesis in cancer and other diseases. Nature 407: 249-257.
    • (2000) Nature , vol.407 , pp. 249-257
    • Carmeliet, P.1    Jain, R.K.2
  • 18
    • 10744228765 scopus 로고    scopus 로고
    • A selective small molecule inhibitor of c-Met kinase inhibits c-Met-dependent phenotypes in vitro and exhibits cyto-reductive antitumor activity in vivo
    • Christensen JG, Schreck R, Burrows J, Kuruganti P, Chan E, Le P et al. (2003). A selective small molecule inhibitor of c-Met kinase inhibits c-Met-dependent phenotypes in vitro and exhibits cyto-reductive antitumor activity in vivo. Cancer Res 63: 7345-7355.
    • (2003) Cancer Res , vol.63 , pp. 7345-7355
    • Christensen, J.G.1    Schreck, R.2    Burrows, J.3    Kuruganti, P.4    Chan Le, E.P.5
  • 19
    • 66149135691 scopus 로고    scopus 로고
    • C-Met-targeted RNA interference inhibits growth and metastasis of glioma U251 cells in vitro
    • Chu SH, Feng DF, Zhang H, Chen ET, Duan ZX, Li XY et al. (2009). c-Met-targeted RNA interference inhibits growth and metastasis of glioma U251 cells in vitro. J Neurooncol 93: 183-189.
    • (2009) J Neurooncol , vol.93 , pp. 183-189
    • Chu, S.H.1    Feng, D.F.2    Zhang, H.3    Chen, E.T.4    Duan, Z.X.5    Li, X.Y.6
  • 20
    • 44449151030 scopus 로고    scopus 로고
    • Drug development of MET inhibitors: Targeting oncogene addiction and expedience
    • Comoglio PM, Giordano S, Trusolino L. (2008). Drug development of MET inhibitors: targeting oncogene addiction and expedience. Nat Rev Drug Discov 7: 504-516.
    • (2008) Nat Rev Drug Discov , vol.7 , pp. 504-516
    • Comoglio, P.M.1    Giordano, S.2    Trusolino, L.3
  • 21
    • 38549156012 scopus 로고    scopus 로고
    • Silencing the MET oncogene leads to regression of experimental tumors and metastases
    • Corso S, Migliore C, Ghiso E, De Rosa G, Comoglio PM, Giordano S. (2008). Silencing the MET oncogene leads to regression of experimental tumors and metastases. Oncogene 27: 684-693.
    • (2008) Oncogene , vol.27 , pp. 684-693
    • Corso, S.1    Migliore, C.2    Ghiso, E.3    De Rosa, G.4    Comoglio, P.M.5    Giordano, S.6
  • 22
    • 0038719721 scopus 로고    scopus 로고
    • CD40-dependent activation of phosphatidylinositol 3-kinase/Akt pathway mediates endothelial cell survival and in vitro angiogenesis
    • Deregibus MC, Buttiglieri S, Russo S, Bussolati B, Camussi G. (2003). CD40-dependent activation of phosphatidylinositol 3-kinase/Akt pathway mediates endothelial cell survival and in vitro angiogenesis. J Biol Chem 278: 18008-18014.
    • (2003) J Biol Chem , vol.278 , pp. 18008-18014
    • Deregibus, M.C.1    Buttiglieri, S.2    Russo, S.3    Bussolati, B.4    Camussi, G.5
  • 23
    • 23944483437 scopus 로고    scopus 로고
    • Cell-penetrating peptides: Tools for intracellular delivery of therapeutics
    • Deshayes S, Morris MC, Divita G, Heitz F. (2005). Cell-penetrating peptides: tools for intracellular delivery of therapeutics. Cell Mol Life Sci 62: 1839-1849.
    • (2005) Cell Mol Life Sci , vol.62 , pp. 1839-1849
    • Deshayes, S.1    Morris, M.C.2    Divita, G.3    Heitz, F.4
  • 25
    • 0035421326 scopus 로고    scopus 로고
    • Hepatocyte growth factor/scatter factor-induced activation of MEK and PI3K signal pathways contributes to expression of proangio-genic cytokines interleukin-8 and vascular endothelial growth factor in head and neck squamous cell carcinoma
    • Dong G, Chen Z, Li ZY, Yeh NT, Bancroft CC, Van Waes C. (2001). Hepatocyte growth factor/scatter factor-induced activation of MEK and PI3K signal pathways contributes to expression of proangio-genic cytokines interleukin-8 and vascular endothelial growth factor in head and neck squamous cell carcinoma. Cancer Res 61: 5911-5918.
    • (2001) Cancer Res , vol.61 , pp. 5911-5918
    • Dong, G.1    Chen, Z.2    Li, Z.Y.3    Yeh, N.T.4    Bancroft, C.C.5    Van Waes, C.6
  • 26
    • 1842360394 scopus 로고    scopus 로고
    • A general strategy for isolation of endothelial cells from murine tissues. Characterization of two endothelial cell lines from the murine lung and subcutaneous sponge implants
    • Dong QG, Bernasconi S, Lostaglio S, De Calmanovici RW, Martin-Padura I, Breviario F et al. (1997). A general strategy for isolation of endothelial cells from murine tissues. Characterization of two endothelial cell lines from the murine lung and subcutaneous sponge implants. Arterioscler Thromb Vasc Biol 17: 1599-1604.
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 1599-1604
    • Dong, Q.G.1    Bernasconi, S.2    Lostaglio, S.3    De Calmanovici, R.W.4    Martin-Padura, I.5    Breviario, F.6
  • 27
    • 0001517943 scopus 로고    scopus 로고
    • Hepatocyte growth factor/scatter factor is an axonal chemoattractant and a neurotrophic factor for spinal motor neurons
    • Ebens A, Brose K, Leonardo ED, Hanson Jr MG, Bladt F, Birchmeier C et al. (1996). Hepatocyte growth factor/scatter factor is an axonal chemoattractant and a neurotrophic factor for spinal motor neurons. Neuron 17: 1157-1172.
    • (1996) Neuron , vol.17 , pp. 1157-1172
    • Ebens, A.1    Brose, K.2    Leonardo, E.D.3    Hanson Jr., M.G.4    Bladt, F.5    Birchmeier, C.6
  • 29
    • 4143136640 scopus 로고    scopus 로고
    • Vascular endothelial growth factor: Basic science and clinical progress
    • Ferrara N. (2004). Vascular endothelial growth factor: basic science and clinical progress. Endocr Rev 25: 581-611.
    • (2004) Endocr Rev , vol.25 , pp. 581-611
    • Ferrara, N.1
  • 30
    • 56749174211 scopus 로고    scopus 로고
    • FLT1 and its ligands VEGFB and PlGF: Drug targets for anti-angiogenic therapy?
    • Fischer C, Mazzone M, Jonckx B, Carmeliet P. (2008). FLT1 and its ligands VEGFB and PlGF: drug targets for anti-angiogenic therapy? Nat Rev Cancer 8: 942-956.
    • (2008) Nat Rev Cancer , vol.8 , pp. 942-956
    • Fischer, C.1    Mazzone, M.2    Jonckx, B.3    Carmeliet, P.4
  • 31
    • 39049130647 scopus 로고    scopus 로고
    • Cell-penetrating peptides for drug delivery across membrane barriers
    • Foged C, Nielsen HM. (2008). Cell-penetrating peptides for drug delivery across membrane barriers. Expert Opin Drug Deliv 5: 105-117.
    • (2008) Expert Opin Drug Deliv , vol.5 , pp. 105-117
    • Foged, C.1    Nielsen, H.M.2
  • 32
    • 0021978223 scopus 로고
    • Tumor angiogenesis
    • Folkman J. (1985). Tumor angiogenesis. Adv Cancer Res 43: 175-203.
    • (1985) Adv Cancer Res , vol.43 , pp. 175-203
    • Folkman, J.1
  • 34
    • 0033950508 scopus 로고    scopus 로고
    • Different point mutations in the met oncogene elicit distinct biological properties
    • Giordano S, Maffe A, Williams TA, Artigiani S, Gual P, Bardelli A et al. (2000). Different point mutations in the met oncogene elicit distinct biological properties. FASEB J 14: 399-406.
    • (2000) FASEB J , vol.14 , pp. 399-406
    • Giordano, S.1    Maffe, A.2    Williams, T.A.3    Artigiani, S.4    Gual, P.5    Bardelli, A.6
  • 35
  • 37
    • 0024434199 scopus 로고
    • Two different laminin domains mediate the differentiation of human endothelial cells into capillary-like structures in vitro
    • Grant DS, Tashiro K, Segui-Real B, Yamada Y, Martin GR, Kleinman HK. (1989). Two different laminin domains mediate the differentiation of human endothelial cells into capillary-like structures in vitro. Cell 58: 933-943.
    • (1989) Cell , vol.58 , pp. 933-943
    • Grant, D.S.1    Tashiro, K.2    Segui-Real, B.3    Yamada, Y.4    Martin, G.R.5    Kleinman, H.K.6
  • 38
    • 0025788025 scopus 로고
    • The tyrosine-phosphorylated hepatocyte growth factor/scatter factor receptor associates with phosphatidylinositol 3-kinase
    • Graziani A, Gramaglia D, Cantley LC, Comoglio PM. (1991). The tyrosine-phosphorylated hepatocyte growth factor/scatter factor receptor associates with phosphatidylinositol 3-kinase. J Biol Chem 266: 22087-22090.
    • (1991) J Biol Chem , vol.266 , pp. 22087-22090
    • Graziani, A.1    Gramaglia, D.2    Cantley, L.C.3    Comoglio, P.M.4
  • 39
    • 13844298046 scopus 로고    scopus 로고
    • Intracellular delivery of large molecules and small particles by cell-penetrating proteins and peptides
    • Gupta B, Levchenko TS, Torchilin VP. (2005). Intracellular delivery of large molecules and small particles by cell-penetrating proteins and peptides. Adv Drug Deliv Rev 57: 637-651.
    • (2005) Adv Drug Deliv Rev , vol.57 , pp. 637-651
    • Gupta, B.1    Levchenko, T.S.2    Torchilin, V.P.3
  • 40
    • 36749042647 scopus 로고    scopus 로고
    • AMG 102, a fully human anti-hepatocyte growth factor/scatter factor neutralizing antibody, enhances the efficacy of temozolomide or docetaxel in U-87MG cells and xenografts
    • Jun HT, Sun J, Rex K, Radinsky R, Kendall R, Coxon A et al. (2007). AMG 102, a fully human anti-hepatocyte growth factor/scatter factor neutralizing antibody, enhances the efficacy of temozolomide or docetaxel in U-87MG cells and xenografts. Clin Cancer Res 13: 6735-6742.
    • (2007) Clin Cancer Res , vol.13 , pp. 6735-6742
    • Jun, H.T.1    Sun, J.2    Rex, K.3    Radinsky, R.4    Kendall, R.5    Coxon, A.6
  • 41
    • 0032563207 scopus 로고    scopus 로고
    • Phospho-inositide 3-kinase induces scattering and tubulogenesis in epithelial cells through a novel pathway
    • Khwaja A, Lehmann K, Marte BM, Downward J. (1998). Phospho-inositide 3-kinase induces scattering and tubulogenesis in epithelial cells through a novel pathway. J Biol Chem 273: 18793-18801.
    • (1998) J Biol Chem , vol.273 , pp. 18793-18801
    • Khwaja, A.1    Lehmann, K.2    Marte, B.M.3    Downward, J.4
  • 42
    • 33644769210 scopus 로고    scopus 로고
    • Systemic anti-hepatocyte growth factor monoclonal antibody therapy induces the regression of intracranial glioma xenografts
    • Kim KJ, Wang L, Su YC, Gillespie GY, Salhotra A, Lal B et al. (2006). Systemic anti-hepatocyte growth factor monoclonal antibody therapy induces the regression of intracranial glioma xenografts. Clin Cancer Res 12: 1292-1298.
    • (2006) Clin Cancer Res , vol.12 , pp. 1292-1298
    • Kim, K.J.1    Wang, L.2    Su, Y.C.3    Gillespie, G.Y.4    Salhotra, A.5    Lal, B.6
  • 44
    • 0042030799 scopus 로고    scopus 로고
    • Grb2-independent recruitment of Gab1 requires the C-terminal lobe and structural integrity of the Met receptor kinase domain
    • Lock LS, Frigault MM, Saucier C, Park M. (2003). Grb2-independent recruitment of Gab1 requires the C-terminal lobe and structural integrity of the Met receptor kinase domain. J Biol Chem 278: 30083-30090.
    • (2003) J Biol Chem , vol.278 , pp. 30083-30090
    • Lock, L.S.1    Frigault, M.M.2    Saucier, C.3    Park, M.4
  • 45
    • 60649116477 scopus 로고    scopus 로고
    • Silencing or fueling metastasis with VEGF inhibitors: Antiangiogenesis revisited
    • Loges S, Mazzone M, Hohensinner P, Carmeliet P. (2009). Silencing or fueling metastasis with VEGF inhibitors: antiangiogenesis revisited. Cancer Cell 15: 167-170.
    • (2009) Cancer Cell , vol.15 , pp. 167-170
    • Loges, S.1    Mazzone, M.2    Hohensinner, P.3    Carmeliet, P.4
  • 46
    • 0028181118 scopus 로고
    • Tyrosines1234-1235 are critical for activation of the tyrosine kinase encoded by the MET proto-oncogene (HGF receptor)
    • Longati P, Bardelli A, Ponzetto C, Naldini L, Comoglio PM. (1994). Tyrosines1234-1235 are critical for activation of the tyrosine kinase encoded by the MET proto-oncogene (HGF receptor). Oncogene 9: 49-57.
    • (1994) Oncogene , vol.9 , pp. 49-57
    • Longati, P.1    Bardelli, A.2    Ponzetto, C.3    Naldini, L.4    Comoglio, P.M.5
  • 47
    • 66849125889 scopus 로고    scopus 로고
    • Inhibition of the met receptor tyrosine kinase signaling enhances the chemosensitivity of glioma cell lines to CDDP through activation of p38 MAPK pathway
    • Lou X, Zhou Q, Yin Y, Zhou C, Shen Y. (2009). Inhibition of the met receptor tyrosine kinase signaling enhances the chemosensitivity of glioma cell lines to CDDP through activation of p38 MAPK pathway. Mol Cancer Ther 8: 1126-1136.
    • (2009) Mol Cancer Ther , vol.8 , pp. 1126-1136
    • Lou, X.1    Zhou, Q.2    Yin, Y.3    Zhou, C.4    Shen, Y.5
  • 48
    • 0037850880 scopus 로고    scopus 로고
    • NK4 (HGF-antagonist/angio-genesis inhibitor) in cancer biology and therapeutics
    • Matsumoto K, Nakamura T. (2003). NK4 (HGF-antagonist/angio-genesis inhibitor) in cancer biology and therapeutics. Cancer Sci 94: 321-327.
    • (2003) Cancer Sci , vol.94 , pp. 321-327
    • Matsumoto, K.1    Nakamura, T.2
  • 49
    • 85047689927 scopus 로고    scopus 로고
    • An uncleavable form of pro-scatter factor suppresses tumor growth and dissemination in mice
    • Mazzone M, Basilico C, Cavassa S, Pennacchietti S, Risio M, Naldini L et al. (2004). An uncleavable form of pro-scatter factor suppresses tumor growth and dissemination in mice. J Clin Invest 114: 1418-1432.
    • (2004) J Clin Invest , vol.114 , pp. 1418-1432
    • Mazzone, M.1    Basilico, C.2    Cavassa, S.3    Pennacchietti, S.4    Risio, M.5    Naldini, L.6
  • 50
  • 51
    • 0037173756 scopus 로고    scopus 로고
    • K252a inhibits the oncogenic properties of Met, the HGF receptor
    • Morotti A, Mila S, Accornero P, Tagliabue E, Ponzetto C. (2002). K252a inhibits the oncogenic properties of Met, the HGF receptor. Oncogene 21: 4885-4893.
    • (2002) Oncogene , vol.21 , pp. 4885-4893
    • Morotti, A.1    Mila, S.2    Accornero, P.3    Tagliabue, E.4    Ponzetto, C.5
  • 52
    • 42049095153 scopus 로고    scopus 로고
    • Cell-penetrating peptides: From molecular mechanisms to therapeutics
    • Morris MC, Deshayes S, Heitz F, Divita G. (2008). Cell-penetrating peptides: from molecular mechanisms to therapeutics. Biol Cell 100: 201-217.
    • (2008) Biol Cell , vol.100 , pp. 201-217
    • Morris, M.C.1    Deshayes, S.2    Heitz, F.3    Divita, G.4
  • 53
    • 0029052214 scopus 로고
    • Hepatocyte growth factor as a hematopoietic regulator
    • Nishino T, Hisha H, Nishino N, Adachi M, Ikehara S. (1995). Hepatocyte growth factor as a hematopoietic regulator. Blood 85: 3093-3100.
    • (1995) Blood , vol.85 , pp. 3093-3100
    • Nishino, T.1    Hisha, H.2    Nishino, N.3    Adachi, M.4    Ikehara, S.5
  • 54
    • 60649106195 scopus 로고    scopus 로고
    • Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis
    • Paez-Ribes M, Allen E, Hudock J, Takeda T, Okuyama H, Vinals F et al. (2009). Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis. Cancer Cell 15: 220-231.
    • (2009) Cancer Cell , vol.15 , pp. 220-231
    • Paez-Ribes, M.1    Allen, E.2    Hudock, J.3    Takeda, T.4    Okuyama, H.5    Vinals, F.6
  • 55
    • 34250312451 scopus 로고    scopus 로고
    • Cell cycle effects resulting from inhibition of hepatocyte growth factor and its receptor c-Met in regenerating rat livers by RNA interference
    • Paranjpe S, Bowen WC, Bell AW, Nejak-Bowen K, Luo JH, Michalopoulos GK. (2007). Cell cycle effects resulting from inhibition of hepatocyte growth factor and its receptor c-Met in regenerating rat livers by RNA interference. Hepatology 45: 1471-1477.
    • (2007) Hepatology , vol.45 , pp. 1471-1477
    • Paranjpe, S.1    Bowen, W.C.2    Bell, A.W.3    Nejak-Bowen, K.4    Luo, J.H.5    Michalopoulos, G.K.6
  • 57
    • 0027219258 scopus 로고
    • A novel recognition motif for phosphatidylinositol 3-kinase binding mediates its association with the hepatocyte growth factor/scatter factor receptor
    • Ponzetto C, Bardelli A, Maina F, Longati P, Panayotou G, Dhand R et al. (1993). A novel recognition motif for phosphatidylinositol 3-kinase binding mediates its association with the hepatocyte growth factor/scatter factor receptor. Mol Cell Biol 13: 4600-4608.
    • (1993) Mol Cell Biol , vol.13 , pp. 4600-4608
    • Ponzetto, C.1    Bardelli, A.2    Maina, F.3    Longati, P.4    Panayotou, G.5    Dhand, R.6
  • 58
    • 0028351702 scopus 로고
    • A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family
    • Ponzetto C, Bardelli A, Zhen Z, Maina F, dalla Zonca P, Giordano S et al. (1994). A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family. Cell 77: 261-271.
    • (1994) Cell , vol.77 , pp. 261-271
    • Ponzetto, C.1    Bardelli, A.2    Zhen, Z.3    Maina, F.4    Dalla Zonca, P.5    Giordano, S.6
  • 59
    • 0031906957 scopus 로고    scopus 로고
    • Agonistic monoclonal antibodies against the Met receptor dissect the biological responses to HGF
    • Prat M, Crepaldi T, Pennacchietti S, Bussolino F, Comoglio PM. (1998). Agonistic monoclonal antibodies against the Met receptor dissect the biological responses to HGF. J Cell Sci 111(Part 2): 237-247.
    • (1998) J Cell Sci , vol.111 , Issue.PART 2 , pp. 237-247
    • Prat, M.1    Crepaldi, T.2    Pennacchietti, S.3    Bussolino, F.4    Comoglio, P.M.5
  • 60
    • 0025954574 scopus 로고
    • The receptor encoded by the human c-MET oncogene is expressed in hepatocytes, epithelial cells and solid tumors
    • Prat M, Narsimhan RP, Crepaldi T, Nicotra MR, Natali PG, Comoglio PM. (1991). The receptor encoded by the human c-MET oncogene is expressed in hepatocytes, epithelial cells and solid tumors. Int J Cancer 49: 323-328.
    • (1991) Int J Cancer , vol.49 , pp. 323-328
    • Prat, M.1    Narsimhan, R.P.2    Crepaldi, T.3    Nicotra, M.R.4    Natali, P.G.5    Comoglio, P.M.6
  • 61
    • 0028899952 scopus 로고
    • Scatter factor/hepatocyte growth factor is essential for liver development
    • Schmidt C, Bladt F, Goedecke S, Brinkmann V, Zschiesche W, Sharpe M et al. (1995). Scatter factor/hepatocyte growth factor is essential for liver development. Nature 373: 699-702.
    • (1995) Nature , vol.373 , pp. 699-702
    • Schmidt, C.1    Bladt, F.2    Goedecke, S.3    Brinkmann, V.4    Zschiesche, W.5    Sharpe, M.6
  • 63
    • 0028842753 scopus 로고
    • In vivo activation of met tyrosine kinase by heterodimeric hepatocyte growth factor molecule promotes angiogenesis
    • Silvagno F, Follenzi A, Arese M, Prat M, Giraudo E, Gaudino G et al. (1995). In vivo activation of met tyrosine kinase by heterodimeric hepatocyte growth factor molecule promotes angiogenesis. Arter-ioscler Thromb Vasc Biol 15: 1857-1865.
    • (1995) Arter-ioscler Thromb Vasc Biol , vol.15 , pp. 1857-1865
    • Silvagno, F.1    Follenzi, A.2    Arese, M.3    Prat, M.4    Giraudo, E.5    Gaudino, G.6
  • 64
    • 45749120326 scopus 로고    scopus 로고
    • Cell-penetrating peptides as delivery vehicles for biology and medicine
    • Stewart KM, Horton KL, Kelley SO. (2008). Cell-penetrating peptides as delivery vehicles for biology and medicine. Org Biomol Chem 6: 2242-2255.
    • (2008) Org Biomol Chem , vol.6 , pp. 2242-2255
    • Stewart, K.M.1    Horton, K.L.2    Kelley, S.O.3
  • 65
    • 0028911690 scopus 로고
    • Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor
    • Uehara Y, Minowa O, Mori C, Shiota K, Kuno J, Noda T et al. (1995). Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor. Nature 373: 702-705.
    • (1995) Nature , vol.373 , pp. 702-705
    • Uehara, Y.1    Minowa, O.2    Mori, C.3    Shiota, K.4    Kuno, J.5    Noda, T.6
  • 67
    • 58149346173 scopus 로고    scopus 로고
    • The hepatocyte growth factor/c-Met signaling pathway as a therapeutic target to inhibit angiogenesis
    • You WK, McDonald DM. (2008). The hepatocyte growth factor/c-Met signaling pathway as a therapeutic target to inhibit angiogenesis. BMB Rep 41: 833-839.
    • (2008) BMB Rep , vol.41 , pp. 833-839
    • You, W.K.1    McDonald, D.M.2
  • 68
    • 0242331653 scopus 로고    scopus 로고
    • Hepatocyte growth factor/scatter factor mediates angiogenesis through positive VEGF and negative thrombospondin 1 regulation
    • Zhang YW, Su Y, Volpert OV, Vande Woude GF. (2003). Hepatocyte growth factor/scatter factor mediates angiogenesis through positive VEGF and negative thrombospondin 1 regulation. Proc Natl Acad Sci USA 100: 12718-12723.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 12718-12723
    • Zhang, Y.W.1    Su, Y.2    Volpert, O.V.3    Vande Woude, G.F.4
  • 69
    • 34249324494 scopus 로고    scopus 로고
    • An orally available small-molecule inhibitor of c-Met, PF-2341066, exhibits cytoreductive antitumor efficacy through antiproliferative and antiangiogenic mechanisms
    • Zou HY, Li Q, Lee JH, Arango ME, McDonnell SR, Yamazaki S et al. (2007). An orally available small-molecule inhibitor of c-Met, PF-2341066, exhibits cytoreductive antitumor efficacy through antiproliferative and antiangiogenic mechanisms. Cancer Res 67: 4408-4417.
    • (2007) Cancer Res , vol.67 , pp. 4408-4417
    • Zou, H.Y.1    Li, Q.2    Lee, J.H.3    Arango, M.E.4    McDonnell, S.R.5    Yamazaki, S.6


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