메뉴 건너뛰기




Volumn 22, Issue 1, 2015, Pages 100-108

Choosing blindly but wisely: Differentially private solicitation of DNA datasets for disease marker discovery

Author keywords

Differential privacy; Genome wide association studies; Haplotype blocks; Privacy preserving techniques; Single nucleotide polymorphisms (SNPs); Test statistics

Indexed keywords

ACCESS TO INFORMATION; ALGORITHM; ARTICLE; DISEASE MARKER; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC DATABASE; GENETIC PRIVACY; HUMAN GENOME; INFORMATION PROCESSING; PRIVACY PRESERVING TECHNIQUE; SINGLE NUCLEOTIDE POLYMORPHISM; CONFIDENTIALITY; GENETIC MARKER; GENOME-WIDE ASSOCIATION STUDY; HUMAN;

EID: 84938572122     PISSN: 10675027     EISSN: 1527974X     Source Type: Journal    
DOI: 10.1136/amiajnl-2014-003043     Document Type: Article
Times cited : (23)

References (26)
  • 1
    • 65949104586 scopus 로고    scopus 로고
    • Genomewide association studies and human disease
    • Hardy J, Singleton A. Genomewide association studies and human disease. N Engl J Med 2009;360:1759-68.
    • (2009) N Engl J Med , vol.360 , pp. 1759-1768
    • Hardy, J.1    Singleton, A.2
  • 3
    • 0025048275 scopus 로고
    • Frequency of three Hex A mutant alleles among Jewish and non-Jewish carriers identified in a Tay-Sachs screening program
    • Paw B, Tieu P, Kaback M, et al. Frequency of three Hex A mutant alleles among Jewish and non-Jewish carriers identified in a Tay-Sachs screening program. Am J Hum Genet 1990;47:698.
    • (1990) Am J Hum Genet , vol.47 , pp. 698
    • Paw, B.1    Tieu, P.2    Kaback, M.3
  • 4
    • 0027034365 scopus 로고
    • Mutations and sequence variations detected in the cystic fibrosis transmembrane conductance regulator (CFTR) gene: a report from the Cystic Fibrosis Genetic Analysis Consortium
    • Tsui LC. Mutations and sequence variations detected in the cystic fibrosis transmembrane conductance regulator (CFTR) gene: a report from the Cystic Fibrosis Genetic Analysis Consortium. Hum Mutat 1992;1:197-203.
    • (1992) Hum Mutat , vol.1 , pp. 197-203
    • Tsui, L.C.1
  • 5
    • 0842308839 scopus 로고    scopus 로고
    • Genetic insights into the clinical diversity of b thalassaemia
    • Thein SL. Genetic insights into the clinical diversity of b thalassaemia. Br J Haematol 2004;124:264-74.
    • (2004) Br J Haematol , vol.124 , pp. 264-274
    • Thein, S.L.1
  • 6
    • 50849101381 scopus 로고    scopus 로고
    • Resolving individuals contributing trace amounts of DNA to highly complex mixtures using high-density SNP genotyping microarrays
    • Homer N, Szelinger S, Redman M, et al. Resolving individuals contributing trace amounts of DNA to highly complex mixtures using high-density SNP genotyping microarrays. PLoS Genet 2008;4:e1000167.
    • (2008) PLoS Genet , vol.4 , pp. e1000167
    • Homer, N.1    Szelinger, S.2    Redman, M.3
  • 7
    • 69349086735 scopus 로고    scopus 로고
    • Genomic privacy and limits of individual detection in a pool
    • Sankararaman S, Obozinski G, Jordan MI, et al. Genomic privacy and limits of individual detection in a pool. Nat Genet 2009;41:965-7.
    • (2009) Nat Genet , vol.41 , pp. 965-967
    • Sankararaman, S.1    Obozinski, G.2    Jordan, M.I.3
  • 8
    • 84979854037 scopus 로고    scopus 로고
    • Policy for Sharing of Data Obtained in NIH Supported or Conducted Genome-Wide Association Studies (GWAS). http://grants.nih.gov/grants/guide/notice-files/NOT-OD-07-088.html
  • 10
    • 84872040426 scopus 로고    scopus 로고
    • Genome-wide association studies
    • Bush WS, Moore JH. Genome-wide association studies. PLoS Comput Biol 2012;8:e1002822.
    • (2012) PLoS Comput Biol , vol.8 , pp. e1002822
    • Bush, W.S.1    Moore, J.H.2
  • 11
    • 77953811255 scopus 로고    scopus 로고
    • New approaches to population stratification in genome-wide association studies
    • Price AL, Zaitlen NA, Reich D, et al. New approaches to population stratification in genome-wide association studies. Nat Rev Genet 2010;11:459-63.
    • (2010) Nat Rev Genet , vol.11 , pp. 459-463
    • Price, A.L.1    Zaitlen, N.A.2    Reich, D.3
  • 15
    • 80052999290 scopus 로고    scopus 로고
    • Assessing and managing risk when sharing aggregate genetic variant data
    • Craig DW, Goor RM, Wang Z, et al. Assessing and managing risk when sharing aggregate genetic variant data. Nat Rev Genet 2011;12:730-6.
    • (2011) Nat Rev Genet , vol.12 , pp. 730-736
    • Craig, D.W.1    Goor, R.M.2    Wang, Z.3
  • 16
    • 67349132836 scopus 로고    scopus 로고
    • Data sharing in genomics-re-shaping scientific practice
    • Kaye J, Heeney C, Hawkins N, et al. Data sharing in genomics-re-shaping scientific practice. Nat Rev Genet 2009; 10:331-5.
    • (2009) Nat Rev Genet , vol.10 , pp. 331-335
    • Kaye, J.1    Heeney, C.2    Hawkins, N.3
  • 17
    • 64849088864 scopus 로고    scopus 로고
    • Subtyping obesity with microarrays: implications for the diagnosis and treatment of obesity
    • Wang S, Sparks L, Xie H, et al. Subtyping obesity with microarrays: implications for the diagnosis and treatment of obesity. Int J Obes 2009;33:481-9.
    • (2009) Int J Obes , vol.33 , pp. 481-489
    • Wang, S.1    Sparks, L.2    Xie, H.3
  • 18
    • 33746335051 scopus 로고    scopus 로고
    • Differential privacy
    • Burkhard M, auf der Heide FM, eds. Springer
    • Dwork C. Differential privacy. In: Automata, languages and programming. Burkhard M, auf der Heide FM, eds. Springer, 2006:1-12.
    • (2006) Automata, languages and programming , pp. 1-12
    • Dwork, C.1
  • 19
    • 18444369013 scopus 로고    scopus 로고
    • The structure of haplotype blocks in the human genome
    • Gabriel SB, Schaffner SF, Nguyen H, et al. The structure of haplotype blocks in the human genome. Science 2002;296: 2225-9.
    • (2002) Science , vol.296 , pp. 2225-2229
    • Gabriel, S.B.1    Schaffner, S.F.2    Nguyen, H.3
  • 20
    • 2442658957 scopus 로고    scopus 로고
    • Haplotype block partitioning and tag SNP selection using genotype data and their applications to association studies
    • Zhang K, Qin ZS, Liu JS, et al. Haplotype block partitioning and tag SNP selection using genotype data and their applications to association studies. Genome Res 2004;14: 908-16.
    • (2004) Genome Res , vol.14 , pp. 908-916
    • Zhang, K.1    Qin, Z.S.2    Liu, J.S.3
  • 21
    • 77954774385 scopus 로고    scopus 로고
    • A Validation Study of Type 2 Diabetes-related Variants of the TCF7L2, HHEX, KCNJ11, and ADIPOQ Genes in one Endogamous Ethnic Group of North India
    • Gupta V, Khadgawat R, Ng HKT, et al. A Validation Study of Type 2 Diabetes-related Variants of the TCF7L2, HHEX, KCNJ11, and ADIPOQ Genes in one Endogamous Ethnic Group of North India. Ann Hum Genet 2010;74:361-8.
    • (2010) Ann Hum Genet , vol.74 , pp. 361-368
    • Gupta, V.1    Khadgawat, R.2    Ng, H.K.T.3
  • 22
    • 84855321526 scopus 로고    scopus 로고
    • Independent validation of genes and polymorphisms reported to be associated with radiation toxicity: a prospective analysis study
    • Barnett GC, Coles CE, Elliott RM, et al. Independent validation of genes and polymorphisms reported to be associated with radiation toxicity: a prospective analysis study. Lancet Oncol 2012;13:65-77.
    • (2012) Lancet Oncol , vol.13 , pp. 65-77
    • Barnett, G.C.1    Coles, C.E.2    Elliott, R.M.3
  • 23
    • 84969213492 scopus 로고    scopus 로고
    • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
    • Burton PR, Clayton DG, Cardon LR, et al. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007;447:661-78.
    • (2007) Nature , vol.447 , pp. 661-678
    • Burton, P.R.1    Clayton, D.G.2    Cardon, L.R.3
  • 24
    • 79952797423 scopus 로고    scopus 로고
    • Transforming growth factor-b signaling pathway in patients with Kawasaki disease
    • Shimizu C, Jain S, Davila S, et al. Transforming growth factor-b signaling pathway in patients with Kawasaki disease. Circulation 2011;4:16-25.
    • (2011) Circulation , vol.4 , pp. 16-25
    • Shimizu, C.1    Jain, S.2    Davila, S.3
  • 25
    • 4043121005 scopus 로고    scopus 로고
    • Kawasaki syndrome
    • Burns JC, GlodéMP. Kawasaki syndrome. Lancet 2004; 364:533-44.
    • (2004) Lancet , vol.364 , pp. 533-544
    • Burns, J.C.1    Glodé, M.P.2
  • 26
    • 0001287271 scopus 로고    scopus 로고
    • Regression shrinkage and selection via the lasso
    • Tibshirani R. Regression shrinkage and selection via the lasso. J R Stat Soc B 1996;58:267-88.
    • (1996) J R Stat Soc B , vol.58 , pp. 267-288
    • Tibshirani, R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.