-
1
-
-
13144306071
-
Genome-wide association studies for common diseases and complex traits
-
DOI 10.1038/nrg1521
-
Hirschhorn, J. N. & Daly, M. J. Genome-wide association studies for common diseases and complex traits. Nature Rev. Genet. 6, 95-108 (2005). (Pubitemid 40179532)
-
(2005)
Nature Reviews Genetics
, vol.6
, Issue.2
, pp. 95-108
-
-
Hirschhorn, J.N.1
Daly, M.J.2
-
2
-
-
20244380171
-
Complement factor H polymorphism in age-related macular degeneration
-
DOI 10.1126/science.1109557
-
Klein, R. J. et al. Complement factor H polymorphism in age-related macular degeneration. Science 308, 385-389 (2005). (Pubitemid 40530070)
-
(2005)
Science
, vol.308
, Issue.5720
, pp. 385-389
-
-
Klein, R.J.1
Zeiss, C.2
Chew, E.Y.3
Tsai, J.-Y.4
Sackler, R.S.5
Haynes, C.6
Henning, A.K.7
SanGiovanni, J.P.8
Mane, S.M.9
Mayne, S.T.10
Bracken, M.B.11
Ferris, F.L.12
Ott, J.13
Barnstable, C.14
Hoh, J.15
-
3
-
-
70349956433
-
Finding the missing heritability of complex diseases
-
Manolio, T. A. et al. Finding the missing heritability of complex diseases. Nature 461, 747-753 (2009).
-
(2009)
Nature
, vol.461
, pp. 747-753
-
-
Manolio, T.A.1
-
4
-
-
79952262073
-
Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci
-
Zhernakova, A. et al. Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci. PLoS Genet. 7, e1002004 (2011).
-
(2011)
PLoS Genet.
, vol.7
-
-
Zhernakova, A.1
-
5
-
-
79955484414
-
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
-
Hollingworth, P. et al. Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nature Genet. 43, 429-435 (2011).
-
(2011)
Nature Genet.
, vol.43
, pp. 429-435
-
-
Hollingworth, P.1
-
6
-
-
79953204259
-
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
-
Schunkert, H. et al. Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nature Genet. 43, 333-338 (2011).
-
(2011)
Nature Genet.
, vol.43
, pp. 333-338
-
-
Schunkert, H.1
-
7
-
-
77955505564
-
Biological, clinical and population relevance of 95 loci for blood lipids
-
Teslovich, T. M. et al. Biological, clinical and population relevance of 95 loci for blood lipids. Nature 466, 707-713 (2010).
-
(2010)
Nature
, vol.466
, pp. 707-713
-
-
Teslovich, T.M.1
-
8
-
-
79955035027
-
Electronic medical records for genetic research: Results of the eMERGE consortium
-
Kho, A. N. et al. Electronic medical records for genetic research: results of the eMERGE consortium. Sci. Transl. Med. 3, 79re1 (2011).
-
(2011)
Sci. Transl. Med.
, vol.3
-
-
Kho, A.N.1
-
9
-
-
31744435871
-
Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies
-
DOI 10.1038/ng1706, PII NG1706
-
Skol, A. D., Scott, L. J., Abecasis, G. R. & Boehnke, M. Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies. Nature Genet. 38, 209-213 (2006). (Pubitemid 43177235)
-
(2006)
Nature Genetics
, vol.38
, Issue.2
, pp. 209-213
-
-
Skol, A.D.1
Scott, L.J.2
Abecasis, G.R.3
Boehnke, M.4
-
10
-
-
77953808087
-
Genotype imputation for genome-wide association studies
-
Marchini, J. & Howie, B. Genotype imputation for genome-wide association studies. Nature Rev. Genet. 11, 499-511 (2010).
-
(2010)
Nature Rev. Genet.
, vol.11
, pp. 499-511
-
-
Marchini, J.1
Howie, B.2
-
11
-
-
84975742565
-
A map of human genome variation from population-scale sequencing
-
Durbin, R. M. et al. A map of human genome variation from population-scale sequencing. Nature 467, 1061-1073 (2010).
-
(2010)
Nature
, vol.467
, pp. 1061-1073
-
-
Durbin, R.M.1
-
12
-
-
40049098166
-
Cumulative association of five genetic variants with prostate cancer
-
DOI 10.1056/NEJMoa075819
-
Zheng, S. L. et al. Cumulative association of five genetic variants with prostate cancer. N. Engl. J. Med. 358, 910-919 (2008). (Pubitemid 351397090)
-
(2008)
New England Journal of Medicine
, vol.358
, Issue.9
, pp. 910-919
-
-
Zheng, S.L.1
Sun, J.2
Wiklund, F.3
Smith, S.4
Stattin, P.5
Li, G.6
Adami, H.-O.7
Hsu, F.-C.8
Zhu, Y.9
Balter, K.10
Kader, A.K.11
Turner, A.R.12
Liu, W.13
Bleecker, E.R.14
Meyers, D.A.15
Duggan, D.16
Carpten, J.D.17
Chang, B.-L.18
Isaacs, W.B.19
Xu, J.20
Gronberg, H.21
more..
-
13
-
-
79953057217
-
Duplications of the neuropeptide receptor gene VIPR2 confer significant risk for schizophrenia
-
Vacic, V. et al. Duplications of the neuropeptide receptor gene VIPR2 confer significant risk for schizophrenia. Nature 471, 499-503 (2011).
-
(2011)
Nature
, vol.471
, pp. 499-503
-
-
Vacic, V.1
-
14
-
-
78650415869
-
Assessing the privacy risks of data sharing in genomics
-
Heeney, C., Hawkins, N., de Vries, J., Boddington, P. & Kaye, J. Assessing the privacy risks of data sharing in genomics. Public Health Genomics 14, 17-25 (2011).
-
(2011)
Public Health Genomics
, vol.14
, pp. 17-25
-
-
Heeney, C.1
Hawkins, N.2
De Vries, J.3
Boddington, P.4
Kaye, J.5
-
15
-
-
73449112365
-
Public access to genome-wide data: Five views on balancing research with privacy and protection
-
Church, G. et al. Public access to genome-wide data: five views on balancing research with privacy and protection. PLoS Genet. 5, e1000665 (2009).
-
(2009)
PLoS Genet.
, vol.5
-
-
Church, G.1
-
16
-
-
78649374846
-
Design of the Coronary ARtery DIsease Genome-Wide Replication and Meta-Analysis (CARDIoGRAM) Study: A genome-wide association meta-analysis involving more than 22 000 cases and 60 000 controls
-
Preuss, M. et al. Design of the Coronary ARtery DIsease Genome-Wide Replication And Meta-Analysis (CARDIoGRAM) Study: a genome-wide association meta-analysis involving more than 22 000 cases and 60 000 controls. Circ. Cardiovasc. Genet. 3, 475-483 (2010).
-
(2010)
Circ. Cardiovasc. Genet.
, vol.3
, pp. 475-483
-
-
Preuss, M.1
-
17
-
-
78049337953
-
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
-
Speliotes, E. K. et al. Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nature Genet. 42, 937-948 (2010).
-
(2010)
Nature Genet.
, vol.42
, pp. 937-948
-
-
Speliotes, E.K.1
-
18
-
-
77951468653
-
The gene, environment association studies consortium (GENEVA): Maximizing the knowledge obtained from GWAS by collaboration across studies of multiple conditions
-
Cornelis, M. C. et al. The gene, environment association studies consortium (GENEVA): maximizing the knowledge obtained from GWAS by collaboration across studies of multiple conditions. Genet. Epidemiol. 34, 364-372 (2010)
-
(2010)
Genet. Epidemiol.
, vol.34
, pp. 364-372
-
-
Cornelis, M.C.1
-
19
-
-
58049194158
-
A framework for interpreting genome-wide association studies of psychiatric disorders
-
The Psychiatric GWAS Consortium Steering Committee
-
The Psychiatric GWAS Consortium Steering Committee. A framework for interpreting genome-wide association studies of psychiatric disorders. Mol. Psychiatry 14, 10-17 (2009).
-
(2009)
Mol. Psychiatry
, vol.14
, pp. 10-17
-
-
-
20
-
-
50949096560
-
The Population Reference Sample, POPRES: A resource for population, disease, and pharmacological genetics research
-
Nelson, M. R. et al. The Population Reference Sample, POPRES: a resource for population, disease, and pharmacological genetics research. Am. J. Hum. Genet. 83, 347-358 (2008).
-
(2008)
Am. J. Hum. Genet.
, vol.83
, pp. 347-358
-
-
Nelson, M.R.1
-
21
-
-
79959503826
-
The International HapMap Project
-
The International HapMap Consortium
-
The International HapMap Consortium. The International HapMap Project. Nature 426, 789-796 (2003).
-
(2003)
Nature
, vol.426
, pp. 789-796
-
-
-
22
-
-
0035173378
-
DbSNP: The NCBI database of genetic variation
-
Sherry, S. T. et al. dbSNP: the NCBI database of genetic variation. Nucleic Acids Res. 29, 308-311 (2001). (Pubitemid 32054478)
-
(2001)
Nucleic Acids Research
, vol.29
, Issue.1
, pp. 308-311
-
-
Sherry, S.T.1
Ward, M.-H.2
Kholodov, M.3
Baker, J.4
Phan, L.5
Smigielski, E.M.6
Sirotkin, K.7
-
23
-
-
34748848639
-
The NCBI dbGaP database of genotypes and phenotypes
-
DOI 10.1038/ng1007-1181, PII NG10071181
-
Mailman, M. D. et al. The NCBI dbGaP database of genotypes and phenotypes. Nature Genet. 39, 1181-1186 (2007). (Pubitemid 47482671)
-
(2007)
Nature Genetics
, vol.39
, Issue.10
, pp. 1181-1186
-
-
Mailman, M.D.1
Feolo, M.2
Jin, Y.3
Kimura, M.4
Tryka, K.5
Bagoutdinov, R.6
Hao, L.7
Kiang, A.8
Paschall, J.9
Phan, L.10
Popova, N.11
Pretel, S.12
Ziyabari, L.13
Lee, M.14
Shao, Y.15
Wang, Z.Y.16
Sirotkin, K.17
Ward, M.18
Kholodov, M.19
Zbicz, K.20
Beck, J.21
Kimelman, M.22
Shevelev, S.23
Preuss, D.24
Yaschenko, E.25
Graeff, A.26
Ostell, J.27
Sherry, S.T.28
more..
-
24
-
-
78651317925
-
The European Nucleotide Archive
-
Leinonen, R. et al. The European Nucleotide Archive. Nucleic Acids Res. 39, D28-D31 (2011).
-
(2011)
Nucleic Acids Res.
, vol.39
-
-
Leinonen, R.1
-
25
-
-
38649091333
-
A navigator for human genome epidemiology
-
Yu, W., Gwinn, M., Clyne, M., Yesupriya, A. & Khoury, M. J. A navigator for human genome epidemiology. Nature Genet. 40, 124-125 (2008).
-
(2008)
Nature Genet.
, vol.40
, pp. 124-125
-
-
Yu, W.1
Gwinn, M.2
Clyne, M.3
Yesupriya, A.4
Khoury, M.J.5
-
26
-
-
58149186476
-
HGVbaseG2P: A central genetic association database
-
Thorisson, G. A. et al. HGVbaseG2P: a central genetic association database. Nucleic Acids Res. 37, D797-D802 (2009).
-
(2009)
Nucleic Acids Res.
, vol.37
-
-
Thorisson, G.A.1
-
27
-
-
0036087166
-
JSNP: A database of common gene variations in the Japanese population
-
Hirakawa, M. et al. JSNP: a database of common gene variations in the Japanese population. Nucleic Acids Res. 30, 158-162 (2002). (Pubitemid 34679529)
-
(2002)
Nucleic Acids Research
, vol.30
, Issue.1
, pp. 158-162
-
-
Hirakawa, M.1
Tanaka, T.2
Hashimoto, Y.3
Kuroda, M.4
Takagi, T.5
Nakamura, Y.6
-
28
-
-
84859542951
-
PheGenI: An integrated resource for browsing genetic association data
-
[online]
-
Hindorff, L. A. et al. PheGenI: an integrated resource for browsing genetic association data. Proc. of the 2011 AMIA Summit on Translational Bioinformatics [online], http://proceedings.amia. org/16pcs7/16pcs7/1 (2011).
-
(2011)
Proc. of the 2011 AMIA Summit on Translational Bioinformatics
-
-
Hindorff, L.A.1
-
29
-
-
50849101381
-
Resolving individuals contributing trace amounts of DNA to highly complex mixtures using high-density SNP genotyping microarrays
-
Homer, N. et al. Resolving individuals contributing trace amounts of DNA to highly complex mixtures using high-density SNP genotyping microarrays. PLoS Genet. 4, e1000167 (2008).
-
(2008)
PLoS Genet.
, vol.4
-
-
Homer, N.1
-
30
-
-
69349086735
-
Genomic privacy and limits of individual detection in a pool
-
Sankararaman, S., Obozinski, G., Jordan, M. I. & Halperin, E. Genomic privacy and limits of individual detection in a pool. Nature Genet. 41, 965-967 (2009).
-
(2009)
Nature Genet.
, vol.41
, pp. 965-967
-
-
Sankararaman, S.1
Obozinski, G.2
Jordan, M.I.3
Halperin, E.4
-
31
-
-
70350632730
-
A new statistic and its power to infer membership in a genome-wide association study using genotype frequencies
-
Jacobs, K. B. et al. A new statistic and its power to infer membership in a genome-wide association study using genotype frequencies. Nature Genet. 41, 1253-1257 (2009).
-
(2009)
Nature Genet.
, vol.41
, pp. 1253-1257
-
-
Jacobs, K.B.1
-
32
-
-
0000776754
-
On the problem of the most efficient tests of statistical hypotheses
-
Neyman, J. & Pearson, E. On the problem of the most efficient tests of statistical hypotheses. Phil. Trans. R. Soc. Lond. A 231, 289-337 (1933).
-
(1933)
Phil. Trans. R. Soc. Lond. A
, vol.231
, pp. 289-337
-
-
Neyman, J.1
Pearson, E.2
-
33
-
-
73449120797
-
Needles in the haystack: Identifying individuals present in pooled genomic data
-
Braun, R., Rowe, W., Schaefer, C., Zhang, J. & Buetow, K. Needles in the haystack: identifying individuals present in pooled genomic data. PLoS Genet. 5, e1000668 (2009).
-
(2009)
PLoS Genet.
, vol.5
-
-
Braun, R.1
Rowe, W.2
Schaefer, C.3
Zhang, J.4
Buetow, K.5
-
34
-
-
74049130896
-
Learning your identity and disease from research papers: Information leaks in genome wide association study
-
Wang, R., Li, Y. F., Wang, X., Tang, H. & Zhou, X. Learning your identity and disease from research papers: information leaks in genome wide association study. Proc. of the 16th ACM Conf. on Computer and Communications Security, 534-544 (2009).
-
(2009)
Proc. of the 16th ACM. Conf. on Computer and Communications Security
, pp. 534-544
-
-
Wang, R.1
Li, Y.F.2
Wang, X.3
Tang, H.4
Zhou, X.5
-
35
-
-
73449105071
-
The limits of individual identification from sample allele frequencies: Theory and statistical analysis
-
Visscher, P. M. & Hill, W. G. The limits of individual identification from sample allele frequencies: theory and statistical analysis. PLoS Genet. 5, e1000628 (2009).
-
(2009)
PLoS Genet.
, vol.5
-
-
Visscher, P.M.1
Hill, W.G.2
-
36
-
-
77956200024
-
On inferring presence of an individual in a mixture: A Bayesian approach
-
Clayton, D. On inferring presence of an individual in a mixture: a Bayesian approach. Biostatistics 11, 661-673 (2010).
-
(2010)
Biostatistics
, vol.11
, pp. 661-673
-
-
Clayton, D.1
-
37
-
-
70350449693
-
Identifying individuals in a complex mixture of DNA with unknown ancestry
-
Sampson, J. & Zhao, H. Identifying individuals in a complex mixture of DNA with unknown ancestry. Stat. Appl. Genet. Mol. Biol. 8, 37 (2009).
-
(2009)
Stat. Appl. Genet. Mol. Biol.
, vol.8
, pp. 37
-
-
Sampson, J.1
Zhao, H.2
-
38
-
-
53349117782
-
Protecting aggregate genomic data
-
Zerhouni, E. A. & Nabel, E. G. Protecting aggregate genomic data. Science 322, 44 (2008).
-
(2008)
Science
, vol.322
, pp. 44
-
-
Zerhouni, E.A.1
Nabel, E.G.2
-
39
-
-
79953907273
-
Is the NIH policy for sharing GWAS data running the risk of being counterproductive?
-
Krawczak, M., Goebel, J. W. & Cooper, D. N. Is the NIH policy for sharing GWAS data running the risk of being counterproductive? Investig. Genet. 1, 3 (2010).
-
(2010)
Investig. Genet.
, vol.1
, pp. 3
-
-
Krawczak, M.1
Goebel, J.W.2
Cooper, D.N.3
-
40
-
-
80053386296
-
Public perspectives regarding data-sharing practices in genomics research
-
24 Mar 2011 doi:10.1159/000324705
-
Haga, S. B. & O'Daniel, J. Public perspectives regarding data-sharing practices in genomics research. Public Health Genomics 24 Mar 2011 (doi:10.1159/000324705).
-
Public Health Genomics
-
-
Haga, S.B.1
O'Daniel, J.2
-
41
-
-
74249091457
-
Technical and policy approaches to balancing patient privacy and data sharing in clinical and translational research
-
Malin, B., Karp, D. & Scheuermann, R. H. Technical and policy approaches to balancing patient privacy and data sharing in clinical and translational research. J. Investig. Med. 58, 11-18 (2010).
-
(2010)
J. Investig. Med.
, vol.58
, pp. 11-18
-
-
Malin, B.1
Karp, D.2
Scheuermann, R.H.3
-
42
-
-
80052639545
-
Predictive value of APOE-ε4 allele for progression from MCI to AD-type dementia: A meta-analysis
-
14 Apr 2011 doi:10.1136/jnnp.2010.231555
-
Elias-Sonnenschein, L. S., Viechtbauer, W., Ramakers, I. H., Verhey, F. R. & Visser, P. J. Predictive value of APOE-ε4 allele for progression from MCI to AD-type dementia: a meta-analysis. J. Neurol. Neurosurg. Psychiatry 14 Apr 2011 (doi:10.1136/jnnp.2010.231555).
-
J. Neurol. Neurosurg. Psychiatry
-
-
Elias-Sonnenschein, L.S.1
Viechtbauer, W.2
Ramakers, I.H.3
Verhey, F.R.4
Visser, P.J.5
-
43
-
-
34548292504
-
PLINK: A tool set for whole-genome association and population-based linkage analyses
-
DOI 10.1086/519795
-
Purcell, S. et al. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am. J. Hum. Genet. 81, 559-575 (2007). (Pubitemid 47330214)
-
(2007)
American Journal of Human Genetics
, vol.81
, Issue.3
, pp. 559-575
-
-
Purcell, S.1
Neale, B.2
Todd-Brown, K.3
Thomas, L.4
Ferreira, M.A.R.5
Bender, D.6
Maller, J.7
Sklar, P.8
De Bakker, P.I.W.9
Daly, M.J.10
Sham, P.C.11
|