Up-regulation of micro-RNA765 in human failing hearts is associated with post-transcriptional regulation of protein phosphatase inhibitor-1 and depressed contractility

European Journal of Heart Failure

Volumn 17, Issue 8, 2015, Pages 782-793

  Cai, Wen Feng ^a   Liu, Guan Sheng ^a   Lam, Chi Keung ^a   Florea, Stela ^a   Qian, Jiang ^a   Zhao, Wen ^a   Pritchard, Tracy ^a   Haghighi, Kobra ^a   Lebeche, Djamel ^b   Lu, Long Jason ^c   Deng, Jingyuan ^c   Fan, Guo Chang ^a   Hajjar, Roger J ^b   Kranias, Evangelia G ^a,d  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c CINCINNATI CHILDREN S HOSPITAL RESEARCH FOUNDATION   (United States)

^d Academy of Athens Biomedical Research Foundation   (Greece)

Author keywords

Calcium cycling; Cardiomyocyte contractility; Heart failure; Inhibitor 1; MicroRNA 765; Protein phosphatase 1

Indexed keywords

CALCIUM ION; MESSENGER RNA; MICRORNA; MICRORNA 765; PHOSPHOLAMBAN; PHOSPHOPROTEIN PHOSPHATASE 1; PROTEIN PHOSPHATASE INHIBITOR 1; PROTEIN TYROSINE PHOSPHATASE INHIBITOR; TROPONIN I; UNCLASSIFIED DRUG; CALCIUM; MIRN765 MICRORNA, HUMAN; PROTEIN PHOSPHATASE INHIBITOR-1; SIGNAL PEPTIDE;

3' UNTRANSLATED REGION; ADULT; AGED; ANIMAL CELL; ARTICLE; BIOINFORMATICS; CALCIUM TRANSPORT; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; FEMALE; HEART FAILURE; HEART MUSCLE CONTRACTILITY; HEK293 CELL LINE; HUMAN; INOTROPISM; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; RAT; REAL TIME POLYMERASE CHAIN REACTION; RNA BINDING; SARCOPLASMIC RETICULUM; TRANSCRIPTION REGULATION; UPREGULATION; ANIMAL; CELL CULTURE; HEART CONTRACTION; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CALCIUM; CELLS, CULTURED; HEART FAILURE; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICRORNAS; MYOCARDIAL CONTRACTION; REAL-TIME POLYMERASE CHAIN REACTION; UP-REGULATION;

EID: 84938554619     PISSN: 13889842     EISSN: 18790844     Source Type: Journal    
DOI: 10.1002/ejhf.323     Document Type: Article

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