-
2
-
-
77955475870
-
Regulation of DNA repair through deSUMOylation and SUMOylation of replication protein A complex
-
Dou H., Huang C., Singh M., Carpenter P.B., Yeh E.T. Regulation of DNA repair through deSUMOylation and SUMOylation of replication protein A complex. Mol. Cell 2010, 39:333-345.
-
(2010)
Mol. Cell
, vol.39
, pp. 333-345
-
-
Dou, H.1
Huang, C.2
Singh, M.3
Carpenter, P.B.4
Yeh, E.T.5
-
3
-
-
79251587803
-
Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy
-
Egan D.F., Shackelford D.B., Mihaylova M.M., Gelino S., Kohnz R.A., Mair W., Vasquez D.S., Joshi A., Gwinn D.M., Taylor R., et al. Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy. Science 2011, 331:456-461.
-
(2011)
Science
, vol.331
, pp. 456-461
-
-
Egan, D.F.1
Shackelford, D.B.2
Mihaylova, M.M.3
Gelino, S.4
Kohnz, R.A.5
Mair, W.6
Vasquez, D.S.7
Joshi, A.8
Gwinn, D.M.9
Taylor, R.10
-
4
-
-
84861859600
-
The structural basis for control of eukaryotic protein kinases
-
Endicott J.A., Noble M.E., Johnson L.N. The structural basis for control of eukaryotic protein kinases. Annu. Rev. Biochem. 2012, 81:587-613.
-
(2012)
Annu. Rev. Biochem.
, vol.81
, pp. 587-613
-
-
Endicott, J.A.1
Noble, M.E.2
Johnson, L.N.3
-
6
-
-
84876320551
-
LKB1 and AMPK and the cancer-metabolism link - ten years after
-
Hardie D.G., Alessi D.R. LKB1 and AMPK and the cancer-metabolism link - ten years after. BMC Biol. 2013, 11:36.
-
(2013)
BMC Biol.
, vol.11
, pp. 36
-
-
Hardie, D.G.1
Alessi, D.R.2
-
7
-
-
33744940842
-
Specification of SUMO1- and SUMO2-interacting motifs
-
Hecker C.M., Rabiller M., Haglund K., Bayer P., Dikic I. Specification of SUMO1- and SUMO2-interacting motifs. J. Biol. Chem. 2006, 281:16117-16127.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 16117-16127
-
-
Hecker, C.M.1
Rabiller, M.2
Haglund, K.3
Bayer, P.4
Dikic, I.5
-
8
-
-
0032495530
-
A serine/threonine kinase gene defective in Peutz-Jeghers syndrome
-
Hemminki A., Markie D., Tomlinson I., Avizienyte E., Roth S., Loukola A., Bignell G., Warren W., Aminoff M., Höglund P., et al. A serine/threonine kinase gene defective in Peutz-Jeghers syndrome. Nature 1998, 391:184-187.
-
(1998)
Nature
, vol.391
, pp. 184-187
-
-
Hemminki, A.1
Markie, D.2
Tomlinson, I.3
Avizienyte, E.4
Roth, S.5
Loukola, A.6
Bignell, G.7
Warren, W.8
Aminoff, M.9
Höglund, P.10
-
9
-
-
84863763440
-
AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress
-
Jeon S.M., Chandel N.S., Hay N. AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress. Nature 2012, 485:661-665.
-
(2012)
Nature
, vol.485
, pp. 661-665
-
-
Jeon, S.M.1
Chandel, N.S.2
Hay, N.3
-
10
-
-
34547683267
-
SUMO junction-what's your function? New insights through SUMO-interacting motifs
-
Kerscher O. SUMO junction-what's your function? New insights through SUMO-interacting motifs. EMBO Rep. 2007, 8:550-555.
-
(2007)
EMBO Rep.
, vol.8
, pp. 550-555
-
-
Kerscher, O.1
-
11
-
-
55549096745
-
SIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1. Possible role in AMP-activated protein kinase activation
-
Lan F., Cacicedo J.M., Ruderman N., Ido Y. SIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1. Possible role in AMP-activated protein kinase activation. J. Biol. Chem. 2008, 283:27628-27635.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 27628-27635
-
-
Lan, F.1
Cacicedo, J.M.2
Ruderman, N.3
Ido, Y.4
-
12
-
-
84877578621
-
Rheb regulates mitophagy induced by mitochondrial energetic status
-
Melser S., Chatelain E.H., Lavie J., Mahfouf W., Jose C., Obre E., Goorden S., Priault M., Elgersma Y., Rezvani H.R., et al. Rheb regulates mitophagy induced by mitochondrial energetic status. Cell Metab. 2013, 17:719-730.
-
(2013)
Cell Metab.
, vol.17
, pp. 719-730
-
-
Melser, S.1
Chatelain, E.H.2
Lavie, J.3
Mahfouf, W.4
Jose, C.5
Obre, E.6
Goorden, S.7
Priault, M.8
Elgersma, Y.9
Rezvani, H.R.10
-
13
-
-
0034680441
-
Covalent modification of p73alpha by SUMO-1. Two-hybrid screening with p73 identifies novel SUMO-1-interacting proteins and a SUMO-1 interaction motif
-
Minty A., Dumont X., Kaghad M., Caput D. Covalent modification of p73alpha by SUMO-1. Two-hybrid screening with p73 identifies novel SUMO-1-interacting proteins and a SUMO-1 interaction motif. J. Biol. Chem. 2000, 275:36316-36323.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 36316-36323
-
-
Minty, A.1
Dumont, X.2
Kaghad, M.3
Caput, D.4
-
14
-
-
58249093939
-
How mitochondria produce reactive oxygen species
-
Murphy M.P. How mitochondria produce reactive oxygen species. Biochem. J. 2009, 417:1-13.
-
(2009)
Biochem. J.
, vol.417
, pp. 1-13
-
-
Murphy, M.P.1
-
15
-
-
0030588674
-
Protection against Fas/APO-1- and tumor necrosis factor-mediated cell death by a novel protein, sentrin
-
Okura T., Gong L., Kamitani T., Wada T., Okura I., Wei C.F., Chang H.M., Yeh E.T. Protection against Fas/APO-1- and tumor necrosis factor-mediated cell death by a novel protein, sentrin. J. Immunol. 1996, 157:4277-4281.
-
(1996)
J. Immunol.
, vol.157
, pp. 4277-4281
-
-
Okura, T.1
Gong, L.2
Kamitani, T.3
Wada, T.4
Okura, I.5
Wei, C.F.6
Chang, H.M.7
Yeh, E.T.8
-
16
-
-
67650720512
-
Systematic study of protein sumoylation: development of a site-specific predictor of SUMOsp 2.0
-
Ren J., Gao X., Jin C., Zhu M., Wang X., Shaw A., Wen L., Yao X., Xue Y. Systematic study of protein sumoylation: development of a site-specific predictor of SUMOsp 2.0. Proteomics 2009, 9:3409-3412.
-
(2009)
Proteomics
, vol.9
, pp. 3409-3412
-
-
Ren, J.1
Gao, X.2
Jin, C.3
Zhu, M.4
Wang, X.5
Shaw, A.6
Wen, L.7
Yao, X.8
Xue, Y.9
-
17
-
-
37149042642
-
A role for LKB1 gene in human cancer beyond the Peutz-Jeghers syndrome
-
Sanchez-Cespedes M. A role for LKB1 gene in human cancer beyond the Peutz-Jeghers syndrome. Oncogene 2007, 26:7825-7832.
-
(2007)
Oncogene
, vol.26
, pp. 7825-7832
-
-
Sanchez-Cespedes, M.1
-
18
-
-
67749111502
-
The LKB1-AMPK pathway: metabolism and growth control in tumour suppression
-
Shackelford D.B., Shaw R.J. The LKB1-AMPK pathway: metabolism and growth control in tumour suppression. Nat. Rev. Cancer 2009, 9:563-575.
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 563-575
-
-
Shackelford, D.B.1
Shaw, R.J.2
-
19
-
-
84873584845
-
LKB1 inactivation dictates therapeutic response of non-small cell lung cancer to the metabolism drug phenformin
-
Shackelford D.B., Abt E., Gerken L., Vasquez D.S., Seki A., Leblanc M., Wei L., Fishbein M.C., Czernin J., Mischel P.S., Shaw R.J. LKB1 inactivation dictates therapeutic response of non-small cell lung cancer to the metabolism drug phenformin. Cancer Cell 2013, 23:143-158.
-
(2013)
Cancer Cell
, vol.23
, pp. 143-158
-
-
Shackelford, D.B.1
Abt, E.2
Gerken, L.3
Vasquez, D.S.4
Seki, A.5
Leblanc, M.6
Wei, L.7
Fishbein, M.C.8
Czernin, J.9
Mischel, P.S.10
Shaw, R.J.11
-
20
-
-
84863393395
-
SUMO-specific protease 1 is critical for early lymphoid development through regulation of STAT5 activation
-
Van Nguyen T., Angkasekwinai P., Dou H., Lin F.M., Lu L.S., Cheng J., Chin Y.E., Dong C., Yeh E.T. SUMO-specific protease 1 is critical for early lymphoid development through regulation of STAT5 activation. Mol. Cell 2012, 45:210-221.
-
(2012)
Mol. Cell
, vol.45
, pp. 210-221
-
-
Van Nguyen, T.1
Angkasekwinai, P.2
Dou, H.3
Lin, F.M.4
Lu, L.S.5
Cheng, J.6
Chin, Y.E.7
Dong, C.8
Yeh, E.T.9
-
21
-
-
77952566949
-
Mechanisms, regulation and consequences of protein SUMOylation
-
Wilkinson K.A., Henley J.M. Mechanisms, regulation and consequences of protein SUMOylation. Biochem. J. 2010, 428:133-145.
-
(2010)
Biochem. J.
, vol.428
, pp. 133-145
-
-
Wilkinson, K.A.1
Henley, J.M.2
-
22
-
-
23044437445
-
Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells
-
Woods A., Dickerson K., Heath R., Hong S.P., Momcilovic M., Johnstone S.R., Carlson M., Carling D. Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells. Cell Metab. 2005, 2:21-33.
-
(2005)
Cell Metab.
, vol.2
, pp. 21-33
-
-
Woods, A.1
Dickerson, K.2
Heath, R.3
Hong, S.P.4
Momcilovic, M.5
Johnstone, S.R.6
Carlson, M.7
Carling, D.8
-
23
-
-
79954517977
-
Structure of mammalian AMPK and its regulation by ADP
-
Xiao B., Sanders M.J., Underwood E., Heath R., Mayer F.V., Carmena D., Jing C., Walker P.A., Eccleston J.F., Haire L.F., et al. Structure of mammalian AMPK and its regulation by ADP. Nature 2011, 472:230-233.
-
(2011)
Nature
, vol.472
, pp. 230-233
-
-
Xiao, B.1
Sanders, M.J.2
Underwood, E.3
Heath, R.4
Mayer, F.V.5
Carmena, D.6
Jing, C.7
Walker, P.A.8
Eccleston, J.F.9
Haire, L.F.10
-
24
-
-
84890963021
-
Structural basis of AMPK regulation by small molecule activators
-
Xiao B., Sanders M.J., Carmena D., Bright N.J., Haire L.F., Underwood E., Patel B.R., Heath R.B., Walker P.A., Hallen S., et al. Structural basis of AMPK regulation by small molecule activators. Nat. Commun. 2013, 4:3017.
-
(2013)
Nat. Commun.
, vol.4
, pp. 3017
-
-
Xiao, B.1
Sanders, M.J.2
Carmena, D.3
Bright, N.J.4
Haire, L.F.5
Underwood, E.6
Patel, B.R.7
Heath, R.B.8
Walker, P.A.9
Hallen, S.10
-
25
-
-
63549129144
-
SUMOylation and De-SUMOylation: wrestling with life's processes
-
Yeh E.T. SUMOylation and De-SUMOylation: wrestling with life's processes. J. Biol. Chem. 2009, 284:8223-8227.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 8223-8227
-
-
Yeh, E.T.1
-
26
-
-
0034595239
-
Ubiquitin-like proteins: new wines in new bottles
-
Yeh E.T., Gong L., Kamitani T. Ubiquitin-like proteins: new wines in new bottles. Gene 2000, 248:1-14.
-
(2000)
Gene
, vol.248
, pp. 1-14
-
-
Yeh, E.T.1
Gong, L.2
Kamitani, T.3
|