-
1
-
-
70449529433
-
Structure and function of the blood-brain barrier
-
Abbott, N. J., Patabendige, A. A. K., Dolman, D. E. M., Yusof, S. R. & Begley, D. J. Structure and function of the blood-brain barrier. Neurobiol. Dis. 37, 13-25 (2010).
-
(2010)
Neurobiol. Dis.
, vol.37
, pp. 13-25
-
-
Abbott, N.J.1
Patabendige, A.A.K.2
Dolman, D.E.M.3
Yusof, S.R.4
Begley, D.J.5
-
2
-
-
38149090292
-
The blood-brain barrier in health and chronic neurodegenerative disorders
-
Zlokovic, B. V. The blood-brain barrier in health and chronic neurodegenerative disorders. Neuron 57, 178-201 (2008).
-
(2008)
Neuron
, vol.57
, pp. 178-201
-
-
Zlokovic, B.V.1
-
3
-
-
12344273726
-
The blood-brain barrier: Bottleneck in brain drug development
-
Pardridge, W. M. The blood-brain barrier: bottleneck in brain drug development. NeuroRx 2, 3-14 (2005).
-
(2005)
NeuroRx
, vol.2
, pp. 3-14
-
-
Pardridge, W.M.1
-
4
-
-
84861233382
-
Stimuli-responsive polymeric nanocarriers for the controlled transport of active compounds: Concepts and applications
-
Fleige, E., Quadir, M. a & Haag, R. Stimuli-responsive polymeric nanocarriers for the controlled transport of active compounds: concepts and applications. Adv. Drug Deliv. Rev. 64, 866-884 (2012).
-
(2012)
Adv. Drug Deliv. Rev.
, vol.64
, pp. 866-884
-
-
Fleige, E.1
Quadir, M.A.2
Haag, R.3
-
5
-
-
36849067019
-
Nanocarriers as an emerging platform for cancer therapy
-
Peer, D. et al. Nanocarriers as an emerging platform for cancer therapy. Nat. Nanotechnol. 2, 751-760 (2007).
-
(2007)
Nat. Nanotechnol.
, vol.2
, pp. 751-760
-
-
Peer, D.1
-
6
-
-
56349166047
-
Applications of nanoparticles in biology
-
De, M., Ghosh, P. S. & Rotello, V. M. Applications of Nanoparticles in Biology. Adv. Mater. 20, 4225-4241 (2008).
-
(2008)
Adv. Mater.
, vol.20
, pp. 4225-4241
-
-
De, M.1
Ghosh, P.S.2
Rotello, V.M.3
-
7
-
-
67649592405
-
Conotoxins: Natural product drug leads
-
Halaia, R. & Craik, D. J. Conotoxins: natural product drug leads. Nat. Prod. Rep. 26, 526-536 (2009).
-
(2009)
Nat. Prod. Rep.
, vol.26
, pp. 526-536
-
-
Halaia, R.1
Craik, D.J.2
-
8
-
-
0347989461
-
Conus venoms: A rich source of novel ion channel-targeted peptides
-
Terlau, H. & Olivera, B. M. Conus venoms: a rich source of novel ion channel-targeted peptides. Physiol. Rev. 84, 41-68 (2004).
-
(2004)
Physiol. Rev.
, vol.84
, pp. 41-68
-
-
Terlau, H.1
Olivera, B.M.2
-
9
-
-
0036930324
-
Conus venom peptides: Reflections from the biology of clades and species
-
Olivera, B. M. Conus venom peptides: reflections from the biology of clades and species. Annu. Rev. Ecol. Syst. 33, 25-42 (2002).
-
(2002)
Annu. Rev. Ecol. Syst.
, vol.33
, pp. 25-42
-
-
Olivera, B.M.1
-
10
-
-
77957743713
-
The Terebridae and teretoxins: Combining phylogeny and anatomy for concerted discovery of bioactive compounds
-
Puillandre, N. & Holford, M. The Terebridae and teretoxins: combining phylogeny and anatomy for concerted discovery of bioactive compounds. BMC Chem. Biol. 10, 7 (2010).
-
(2010)
BMC Chem. Biol.
, vol.10
, pp. 7
-
-
Puillandre, N.1
Holford, M.2
-
11
-
-
84908548800
-
A bioinformatics survey for conotoxin-like sequences in three turrid snail venom duct transcriptomes
-
Gonzales, D. T. T. & Saloma, C. P. A bioinformatics survey for conotoxin-like sequences in three turrid snail venom duct transcriptomes. Toxicon 92, 66-74 (2014).
-
(2014)
Toxicon
, vol.92
, pp. 66-74
-
-
Gonzales, D.T.T.1
Saloma, C.P.2
-
12
-
-
9144272640
-
Ziconotide: Neuronal calcium channel blocker for treating severe chronic pain
-
Miljanich, G. P. Ziconotide: neuronal calcium channel blocker for treating severe chronic pain. Curr. Med. Chem. 11, 3029-3040 (2004).
-
(2004)
Curr. Med. Chem.
, vol.11
, pp. 3029-3040
-
-
Miljanich, G.P.1
-
13
-
-
34249017949
-
Ziconotide: A review of its pharmacology and use in the treatment of pain
-
McGivern, J. G. Ziconotide: a review of its pharmacology and use in the treatment of pain. Neuropsychiatr. Dis. Treat. 3, 69-85 (2007).
-
(2007)
Neuropsychiatr. Dis. Treat.
, vol.3
, pp. 69-85
-
-
McGivern, J.G.1
-
14
-
-
84876049293
-
Analgesia and central side-effects: Two separate dimensions of morphine response
-
Droney, J. M. et al. Analgesia and central side-effects: two separate dimensions of morphine response. Br. J. Clin. Pharmacol. 75, 1340-1350 (2013).
-
(2013)
Br. J. Clin. Pharmacol.
, vol.75
, pp. 1340-1350
-
-
Droney, J.M.1
-
15
-
-
35748943212
-
Pharmacologic management of neuropathic pain: Evidence-based recommendations
-
Dworkin, R. H. et al. Pharmacologic management of neuropathic pain: evidence-based recommendations. Pain 132, 237-251 (2007).
-
(2007)
Pain
, vol.132
, pp. 237-251
-
-
Dworkin, R.H.1
-
16
-
-
77953823105
-
EFNS guidelines on the pharmacological treatment of neuropathic pain: 2010 revision
-
Attal, N. et al. EFNS guidelines on the pharmacological treatment of neuropathic pain: 2010 revision. Eur. J. Neurol. 17, 1113-e88 (2010).
-
(2010)
Eur. J. Neurol.
, vol.17
, pp. 1113-e88
-
-
Attal, N.1
-
17
-
-
65249157086
-
Conotoxins: Molecular and therapeutic targets
-
Lewis, R. J. Conotoxins: molecular and therapeutic targets. Prog. Mol. Subcell. Biol. 46, 45-65 (2009).
-
(2009)
Prog. Mol. Subcell. Biol.
, vol.46
, pp. 45-65
-
-
Lewis, R.J.1
-
18
-
-
52949118506
-
Conus venoms - A rich source of peptide-based therapeutics
-
Han, T. S., Teichert, R. W., Olivera, B. M. & Bulaj, G. Conus venoms - a rich source of peptide-based therapeutics. Curr. Pharm. Des. 14, 2462-2479 (2008).
-
(2008)
Curr. Pharm. Des.
, vol.14
, pp. 2462-2479
-
-
Han, T.S.1
Teichert, R.W.2
Olivera, B.M.3
Bulaj, G.4
-
19
-
-
84863462294
-
Conotoxins that confer therapeutic possibilities
-
Essack, M., Bajic, V. B. & Archer, J. a C. Conotoxins that confer therapeutic possibilities. Mar. Drugs 10, 1244-1265 (2012).
-
(2012)
Mar. Drugs
, vol.10
, pp. 1244-1265
-
-
Essack, M.1
Bajic, V.B.2
Archer, J.A.C.3
-
20
-
-
25444448796
-
Engineering stable peptide toxins by means of backbone cyclization: Stabilization of the alpha-conotoxin MII
-
Clark, R. J. et al. Engineering stable peptide toxins by means of backbone cyclization: stabilization of the alpha-conotoxin MII. Proc. Natl. Acad. Sci. USA. 102, 13767-13772 (2005).
-
(2005)
Proc. Natl. Acad. Sci. USA.
, vol.102
, pp. 13767-13772
-
-
Clark, R.J.1
-
21
-
-
33750460621
-
Cyclic MrIA: A stable and potent cyclic conotoxin with a novel topological fold that targets the norepinephrine transporter
-
Lovelace, E. S. et al. Cyclic MrIA: a stable and potent cyclic conotoxin with a novel topological fold that targets the norepinephrine transporter. J. Med. Chem. 49, 6561-6568 (2006).
-
(2006)
J. Med. Chem.
, vol.49
, pp. 6561-6568
-
-
Lovelace, E.S.1
-
22
-
-
34547106305
-
Oral absorption and in vivo biodistribution of alpha-conotoxin MII and a lipidic analogue
-
Blanchfield, J. T. et al. Oral absorption and in vivo biodistribution of alpha-conotoxin MII and a lipidic analogue. Biochem. Biophys. Res. Commun. 361, 97-102 (2007).
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.361
, pp. 97-102
-
-
Blanchfield, J.T.1
-
23
-
-
77956502216
-
The engineering of an orally active conotoxin for the treatment of neuropathic pain
-
Clark, R. J. et al. The engineering of an orally active conotoxin for the treatment of neuropathic pain. Angew. Chem. Int. Ed. Engl. 49, 6545-6548 (2010).
-
(2010)
Angew. Chem. Int. Ed. Engl.
, vol.49
, pp. 6545-6548
-
-
Clark, R.J.1
-
24
-
-
9144230737
-
Intrathecal ziconotide in the treatment of refractory pain in patients with cancer or AIDS: A randomized controlled trial
-
Staats, P. S. et al. Intrathecal ziconotide in the treatment of refractory pain in patients with cancer or AIDS: a randomized controlled trial. J. Am. Med. Assoc. 291, 63-70 (2004).
-
(2004)
J. Am. Med. Assoc.
, vol.291
, pp. 63-70
-
-
Staats, P.S.1
-
25
-
-
80855139469
-
Blood-brain barrier transport of Tat peptide and polyethylene glycol decorated gelatin-siloxane nanoparticle
-
Tian, X. et al. Blood-brain barrier transport of Tat peptide and polyethylene glycol decorated gelatin-siloxane nanoparticle. Mater. Lett. 68, 94-96 (2012).
-
(2012)
Mater. Lett.
, vol.68
, pp. 94-96
-
-
Tian, X.1
-
26
-
-
64749094374
-
Development of an antisense RNA delivery system using conjugates of the MS2 bacteriophage capsids and HIV-1 TAT cell-penetrating peptide
-
Wei, B. et al. Development of an antisense RNA delivery system using conjugates of the MS2 bacteriophage capsids and HIV-1 TAT cell-penetrating peptide. Biomed. Pharmacother. 63, 313-318 (2009).
-
(2009)
Biomed. Pharmacother.
, vol.63
, pp. 313-318
-
-
Wei, B.1
-
27
-
-
38549180565
-
Biologically active core/shell nanoparticles self-assembled from cholesterol-terminated PEG-TAT for drug delivery across the blood-brain barrier
-
Liu, L. et al. Biologically active core/shell nanoparticles self-assembled from cholesterol-terminated PEG-TAT for drug delivery across the blood-brain barrier. Biomaterials 29, 1509-1517 (2008).
-
(2008)
Biomaterials
, vol.29
, pp. 1509-1517
-
-
Liu, L.1
-
28
-
-
79960923510
-
Genetically programmed in vivo packaging of protein cargo and its controlled release from bacteriophage P22
-
O'Neil, A., Reichhardt, C., Johnson, B., Prevelige, P. E. & Douglas, T. Genetically programmed in vivo packaging of protein cargo and its controlled release from bacteriophage P22. Angew. Chem. Int. Ed. Engl. 50, 7425-7428 (2011).
-
(2011)
Angew. Chem. Int. Ed. Engl.
, vol.50
, pp. 7425-7428
-
-
O'Neil, A.1
Reichhardt, C.2
Johnson, B.3
Prevelige, P.E.4
Douglas, T.5
-
29
-
-
78650235303
-
Optimization of oxidative folding methods for cysteine-rich peptides: A study of conotoxins containing three disulfide bridges
-
Steiner, A. M. & Bulaj, G. Optimization of oxidative folding methods for cysteine-rich peptides: a study of conotoxins containing three disulfide bridges. J. Pept. Sci. 17, 1-7 (2011).
-
(2011)
J. Pept. Sci.
, vol.17
, pp. 1-7
-
-
Steiner, A.M.1
Bulaj, G.2
-
30
-
-
84862951933
-
An in vitro transport model for rapid screening and predicting the permeability of candidate compounds at blood-brain barrier
-
Yang, Z.-H. et al. An in vitro transport model for rapid screening and predicting the permeability of candidate compounds at blood-brain barrier. J. Asian Nat. Prod. Res. 13, 1087-1097 (2011).
-
(2011)
J. Asian Nat. Prod. Res.
, vol.13
, pp. 1087-1097
-
-
Yang, Z.-H.1
-
31
-
-
17644364387
-
Rat brain endothelial cell lines for the study of blood-brain barrier permeability and transport functions
-
Roux, F. & Couraud, P.-O. Rat Brain Endothelial Cell Lines for the Study of Blood-Brain Barrier Permeability and Transport Functions. Cell. Mol. Neurobiol. 25, 41-57 (2005).
-
(2005)
Cell. Mol. Neurobiol.
, vol.25
, pp. 41-57
-
-
Roux, F.1
Couraud, P.-O.2
-
32
-
-
84873098624
-
Rapid method of quantification of tight-junction organization using image analysis
-
Terryn, C. et al. Rapid method of quantification of tight-junction organization using image analysis. Cytometry. A 83, 235-241 (2013).
-
(2013)
Cytometry. A
, vol.83
, pp. 235-241
-
-
Terryn, C.1
-
33
-
-
84877944837
-
Epithelial barrier assembly requires coordinated activity of multiple domains of the tight junction protein ZO-1
-
Rodgers, L. S., Beam, M. T., Anderson, J. M. & Fanning, A. S. Epithelial barrier assembly requires coordinated activity of multiple domains of the tight junction protein ZO-1. J. Cell Sci. 126, 1565-1575 (2013).
-
(2013)
J. Cell Sci.
, vol.126
, pp. 1565-1575
-
-
Rodgers, L.S.1
Beam, M.T.2
Anderson, J.M.3
Fanning, A.S.4
-
34
-
-
79952159138
-
The Role of P-Glycoprotein in Transport of Danshensu across the Blood-Brain Barrier
-
Yu, P.-F. et al. The Role of P-Glycoprotein in Transport of Danshensu across the Blood-Brain Barrier. Evid. Based. Complement. Alternat. Med. 2011, 713523 (2011).
-
(2011)
Evid. Based. Complement. Alternat. Med.
, vol.2011
, pp. 713523
-
-
Yu, P.-F.1
-
35
-
-
3242785620
-
Importance of P-glycoprotein at blood-tissue barriers
-
Fromm, M. F. Importance of P-glycoprotein at blood-tissue barriers. Trends Pharmacol. Sci. 25, 423-429 (2004).
-
(2004)
Trends Pharmacol. Sci.
, vol.25
, pp. 423-429
-
-
Fromm, M.F.1
-
36
-
-
84878024482
-
Functionalization with TAT-Peptide Enhances Blood-Brain Barrier Crossing in vitro of Nanoliposomes Carrying a Curcumin-Derivative to Bind Amyloid-β Peptide
-
Sancini, G. et al. Functionalization with TAT-Peptide Enhances Blood-Brain Barrier Crossing In vitro of Nanoliposomes Carrying a Curcumin-Derivative to Bind Amyloid-β Peptide. J. Nanomed. Nanotechnol. 4, 171 (2013).
-
(2013)
J. Nanomed. Nanotechnol.
, vol.4
, pp. 171
-
-
Sancini, G.1
-
37
-
-
84862951933
-
An in vitro transport model for rapid screening and predicting the permeability of candidate compounds at blood - Brain barrier
-
Yang, Z.-H., Sun, X., Mei, C. & Al, E. An in vitro transport model for rapid screening and predicting the permeability of candidate compounds at blood - brain barrier. J. Asian Nat. Prod. Res. 13, 1087-1097 (2011).
-
(2011)
J. Asian Nat. Prod. Res.
, vol.13
, pp. 1087-1097
-
-
Yang, Z.-H.1
Sun, X.2
Mei, C.3
-
38
-
-
79952188400
-
Transport of Poly(n-butylcyano-acrylate) nanoparticles across the blood-brain barrier in vitro and their influence on barrier integrity
-
Rempe, R., Cramer, S., Hüwel, S. & Galla, H.-J. Transport of Poly(n-butylcyano-acrylate) nanoparticles across the blood-brain barrier in vitro and their influence on barrier integrity. Biochem. Biophys. Res. Commun. 406, 64-69 (2011).
-
(2011)
Biochem. Biophys. Res. Commun.
, vol.406
, pp. 64-69
-
-
Rempe, R.1
Cramer, S.2
Hüwel, S.3
Galla, H.-J.4
-
39
-
-
84886037433
-
Uptake and transport of superparamagnetic iron oxide nanoparticles through human brain capillary endothelial cells
-
Thomsen, L. B. et al. Uptake and transport of superparamagnetic iron oxide nanoparticles through human brain capillary endothelial cells. ACS Chem. Neurosci. 4, 1352-1360 (2013).
-
(2013)
ACS Chem. Neurosci.
, vol.4
, pp. 1352-1360
-
-
Thomsen, L.B.1
-
40
-
-
33748648777
-
Cargo-dependent mode of uptake and bioavailability of TAT-containing proteins and peptides in living cells
-
Tünnemann, G. et al. Cargo-dependent mode of uptake and bioavailability of TAT-containing proteins and peptides in living cells. FASEB J. 20, 1775-1784 (2006).
-
(2006)
FASEB J.
, vol.20
, pp. 1775-1784
-
-
Tünnemann, G.1
-
41
-
-
0030948209
-
Structure-internalization relationship for absorptive-mediated endocytosis of basic peptides at the blood-brain barrier
-
Tamai, I. et al. Structure-internalization relationship for absorptive-mediated endocytosis of basic peptides at the blood-brain barrier. J. Pharmacol. Exp. Ther. 280, 410-415 (1997).
-
(1997)
J. Pharmacol. Exp. Ther.
, vol.280
, pp. 410-415
-
-
Tamai, I.1
-
42
-
-
57149110011
-
CNS delivery via adsorptive transcytosis
-
Hervé, F., Ghinea, N. & Scherrmann, J.-M. CNS delivery via adsorptive transcytosis. AAPS J. 10, 455-472 (2008).
-
(2008)
AAPS J.
, vol.10
, pp. 455-472
-
-
Hervé, F.1
Ghinea, N.2
Scherrmann, J.-M.3
-
43
-
-
0024595608
-
Hypertonic media inhibit receptor-mediated endocytosis by blocking clathrin-coated pit formation
-
Heuser, J. E. & Anderson, R. G. Hypertonic media inhibit receptor-mediated endocytosis by blocking clathrin-coated pit formation. J. Cell Biol. 108, 389-400 (1989).
-
(1989)
J. Cell Biol.
, vol.108
, pp. 389-400
-
-
Heuser, J.E.1
Anderson, R.G.2
-
44
-
-
84867014546
-
Rab11 regulates exocytosis of recycling vesicles at the plasma membrane
-
Takahashi, S. et al. Rab11 regulates exocytosis of recycling vesicles at the plasma membrane. J. Cell Sci. 125, 4049-4057 (2012).
-
(2012)
J. Cell Sci.
, vol.125
, pp. 4049-4057
-
-
Takahashi, S.1
-
45
-
-
0021061819
-
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
-
Mosmann, T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 65, 55-63 (1983).
-
(1983)
J. Immunol. Methods
, vol.65
, pp. 55-63
-
-
Mosmann, T.1
-
46
-
-
82755187264
-
Applications of viral nanoparticles in medicine
-
Yildiz, I., Shukla, S. & Steinmetz, N. F. Applications of viral nanoparticles in medicine. Curr. Opin. Biotechnol. 22, 901-908 (2011).
-
(2011)
Curr. Opin. Biotechnol.
, vol.22
, pp. 901-908
-
-
Yildiz, I.1
Shukla, S.2
Steinmetz, N.F.3
|