Analgesia and central side-effects: Two separate dimensions of morphine response

British Journal of Clinical Pharmacology

Volumn 75, Issue 5, 2013, Pages 1340-1350

  Droney, Joanne M ^a,b   Gretton, Sophy K ^a,b   Sato, Hiroe ^a   Ross, Joy R ^a,b,c   Branford, Ruth ^a,b   Welsh, Kenneth I ^a   Cookson, William ^a   Riley, Julia ^a,b,c  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b ROYAL MARSDEN HOSPITAL   (United Kingdom)

^c ROYAL BROMPTON HOSPITAL   (United Kingdom)

Author keywords

Analgesia; Morphine; Opioid; Polymorphism; Principal components

Indexed keywords

MORPHINE; OPIATE RECEPTOR; OPRD1 PROTEIN; OPRK1 PROTEIN; OPRM1 PROTEIN; UNCLASSIFIED DRUG;

ADULT; AGED; ANALGESIA; ARTICLE; BREAST CANCER; CANCER PATIENT; CONFUSION; CONTROLLED STUDY; CORRELATION ANALYSIS; DIGESTIVE SYSTEM CANCER; DISEASE SEVERITY; DROWSINESS; DRUG DOSE TITRATION; DRUG TOLERABILITY; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENOTYPE; GYNECOLOGIC CANCER; HALLUCINATION; HEAD AND NECK CANCER; HUMAN; LUNG CANCER; MAJOR CLINICAL STUDY; MALE; NAUSEA; NIGHTMARE; OBSERVATIONAL STUDY; PAIN; PAIN ASSESSMENT; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROSTATE CANCER; RESIDUAL PAIN; SARCOMA; SINGLE NUCLEOTIDE POLYMORPHISM; SKIN CANCER; STATISTICAL MODEL; TREATMENT RESPONSE;

ADULT; AGED; AGED, 80 AND OVER; ANALGESIA; ANALGESICS, OPIOID; FEMALE; GENOTYPING TECHNIQUES; HUMANS; MALE; MIDDLE AGED; MORPHINE; NEOPLASMS; PAIN; PAIN MEASUREMENT; POLYMORPHISM, SINGLE NUCLEOTIDE; PRINCIPAL COMPONENT ANALYSIS; PROSPECTIVE STUDIES; RECEPTORS, OPIOID; RECEPTORS, OPIOID, DELTA; RECEPTORS, OPIOID, KAPPA; RECEPTORS, OPIOID, MU; REGRESSION ANALYSIS; YOUNG ADULT;

EID: 84876049293     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/bcp.12008     Document Type: Article

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