Synthesis and anticancer activity of novel curcumin-quinolone hybrids

Bioorganic and Medicinal Chemistry Letters

Volumn 25, Issue 17, 2015, Pages 3601-3605

  Raghavan, Saiharish ^a   Manogaran, Prasath ^a   Gadepalli Narasimha, Krishna Kumari ^a   Kalpattu Kuppusami, Balasubramanian ^a,b   Mariyappan, Palanivelu ^a   Gopalakrishnan, Anjana ^a   Venkatraman, Ganesh ^a  

^a SRI RAMACHANDRA UNIVERSITY   (India)

^b INDIAN INSTITUTE OF TECHNOLOGY MADRAS   (India)

Author keywords

Annexin V; Cell cycle analysis; Curcumin quinolone hybrids; MTT assay

Indexed keywords

3 FORMYL 2 QUINOLONE DERIVATIVE; ANTINEOPLASTIC AGENT; CISPLATIN; CURCUMIN; QUINOLONE DERIVATIVE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; VANILLIN;

A549 CELL LINE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL LINE; CELL CYCLE PROGRESSION; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; CYTOLOGY; CYTOTOXICITY; DRUG MECHANISM; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; FLOW CYTOMETRY; G2 PHASE CELL CYCLE CHECKPOINT; IC50; IN VITRO STUDY; MCF 7 CELL LINE; MTT ASSAY; OXIDATIVE STRESS; PHASE CONTRAST MICROSCOPY; S PHASE CELL CYCLE CHECKPOINT; ANALOGS AND DERIVATIVES; CELL CYCLE; CHEMISTRY; DRUG EFFECTS; HUMAN; METABOLISM; NEOPLASMS; SYNTHESIS; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; CURCUMIN; HUMANS; NEOPLASMS; QUINOLONES; REACTIVE OXYGEN SPECIES;

EID: 84938423704     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2015.06.068     Document Type: Article

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