HOTAIR long non-coding RNA is a negative prognostic factor not only in primary tumors, but also in the blood of colorectal cancer patients

Carcinogenesis

Volumn 35, Issue 7, 2014, Pages

  Svoboda, Miroslav ^a,b   Slyskova, Jana ^a,b   Schneiderova, Michaela ^c   Makovicky, Peter ^d   Bielik, Ludovit ^a,b   Levy, Miroslav ^e   Lipska, Ludmila ^e   Hemmelova, Beata ^f   Kala, Zdenek ^f   Protivankova, Marketa ^f   Vycital, Ondrej ^b   Liska, Vaclav ^b   Schwarzova, Lucie ^b   Vodickova, Ludmila ^a,b   Vodicka, Pavel ^a,b  

^a INSTITUTE OF EXPERIMENTAL MEDICINE   (Czech Republic)

^b CHARLES UNIVERSITY   (Czech Republic)

^c CHARLES UNIVERSITY   (Czech Republic)

^d CZECH UNIVERSITY OF LIFE SCIENCES PRAGUE   (Czech Republic)

^e FAKULTNÍ THOMAYEROVA NEMOCNICE   (Czech Republic)

^f UNIVERSITY HOSPITAL BRNO   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

HOMEOBOX TRANSCRIPT ANTISENSE INTERGENIC RNA; LONG UNTRANSLATED RNA; UNCLASSIFIED DRUG; HOTAIR LONG UNTRANSLATED RNA, HUMAN; MESSENGER RNA; TUMOR MARKER;

ADULT; AGED; ARTICLE; BLOOD DONOR; BLOOD SAMPLING; CANCER LOCALIZATION; CANCER MORTALITY; CANCER PROGNOSIS; CANCER STAGING; CANCER TISSUE; CHEMORADIOTHERAPY; COLORECTAL CANCER; CONTROLLED STUDY; FEMALE; GENE OVEREXPRESSION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MALE; MICROSATELLITE INSTABILITY; OVERALL SURVIVAL; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIMARY TUMOR; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; BLOOD; CANCER GRADING; CASE CONTROL STUDY; COLON; COLORECTAL TUMOR; COMPARATIVE STUDY; FOLLOW UP; GENETICS; METABOLISM; MIDDLE AGED; MORTALITY; PROGNOSIS; REAL TIME POLYMERASE CHAIN REACTION; RECTUM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SURVIVAL RATE; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; CASE-CONTROL STUDIES; COLON; COLORECTAL NEOPLASMS; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; NEOPLASM GRADING; NEOPLASM STAGING; PROGNOSIS; REAL-TIME POLYMERASE CHAIN REACTION; RECTUM; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, LONG NONCODING; RNA, MESSENGER; SURVIVAL RATE; TUMOR MARKERS, BIOLOGICAL;

EID: 84904015674     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgu055     Document Type: Article

References (18)

1. Bertone, P. et al. (2004) Global identification of human transcribed sequences with genome tiling arrays. Science, 306, 2242-2246.
2. Carninci, P. et al.; FANTOM Consortium; RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group). (2005) The transcriptional landscape of the mammalian genome. Science, 309, 1559-1563.
3. Derrien, T. et al. (2012) The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression. Genome Res., 22, 1775-1789.
4. Wapinski, O. et al. (2011) Long noncoding RNAs and human disease. Trends Cell Biol., 21, 354-361.
5. Zeng, X. et al. (2011) Phosphorylation of EZH2 by CDK1 and CDK2: a possible regulatory mechanism of transmission of the H3K27me3 epigenetic mark through cell divisions. Cell Cycle, 10, 579-583.
6. Niinuma, T. et al. (2012) Upregulation of miR-196a and HOTAIR drive malignant character in gastrointestinal stromal tumors. Cancer Res., 72, 1126-1136.
7. Gupta, R.A. et al. (2010) Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis. Nature, 464, 1071-1076.
8. Kim, K. et al. (2013) HOTAIR is a negative prognostic factor and exhibits pro-oncogenic activity in pancreatic cancer. Oncogene, 32, 1616-1625.
9. Geng, Y.J. et al. (2011) Large intervening non-coding RNA HOTAIR is associated with hepatocellular carcinoma progression. J. Int. Med. Res., 39, 2119-2128.
10. Kogo, R. et al. (2011) Long noncoding RNA HOTAIR regulates polycombdependent chromatin modification and is associated with poor prognosis in colorectal cancers. Cancer Res., 71, 6320-6326.
11. Ahnen, D.J. (2011) The American College of Gastroenterology Emily Couric Lecture-the adenoma-carcinoma sequence revisited: has the era of genetic tailoring finally arrived? Am. J. Gastroenterol., 106, 190-198.
12. Edge, S.B. et al. (2010) The American Joint Committee on Cancer: the 7th edition of the AJCC cancer staging manual and the future of TNM. Ann. Surg. Oncol., 17, 1471-1474.
13. Buhard, O. et al. (2006) Multipopulation analysis of polymorphisms in five mononucleotide repeats used to determine the microsatellite instability status of human tumors. J. Clin. Oncol., 24, 241-251.
14. Rinn, J.L. et al. (2007) Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs. Cell, 129, 1311-1323.
15. Chisholm, K.M. et al. (2012) Detection of long non-coding RNA in archival tissue: correlation with polycomb protein expression in primary and metastatic breast carcinoma. PLoS One, 7, e47998.
16. Suetsugu, A. et al. (2013) Imaging exosome transfer from breast cancer cells to stroma at metastatic sites in orthotopic nude-mouse models. Adv. Drug Deliv. Rev., 65, 383-390.
17. Nie, Y. et al. (2013) Long non-coding RNA HOTAIR is an independent prognostic marker for nasopharyngeal carcinoma progression and survival. Cancer Sci., 104, 458-464.
18. Pritchard, C.C. et al. (2011) Colorectal cancer molecular biology moves into clinical practice. Gut, 60, 116-129.